메뉴 건너뛰기




Volumn 8, Issue November, 2014, Pages 1-13

Abnormal emotional learning in a rat model of autism exposed to valproic acid in utero

Author keywords

Amygdala; Autism; Emotion; Learning; Memory; Pavlovian fear conditioning; Valproic acid

Indexed keywords

VALPROIC ACID;

EID: 84927524054     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.0038     Document Type: Article
Times cited : (45)

References (74)
  • 1
    • 65249109439 scopus 로고    scopus 로고
    • MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome
    • Adachi, M., Autry, A. E., Covington, H. E. 3rd., and Monteggia, L. M. (2009). MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J. Neurosci. 29, 4218-4227. doi: 10.1523/JNEUROSCI.4225-08.2009.
    • (2009) J. Neurosci , vol.29 , pp. 4218-4227
    • Adachi, M.1    Autry, A.E.2    Covington, H.E.3    Monteggia, L.M.4
  • 2
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir, R. E., Van Den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U., and Zoghbi, H. Y. (1999). Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23, 185-188. doi: 10.1038/13810.
    • (1999) Nat. Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 4
    • 28844435811 scopus 로고    scopus 로고
    • The orbitofrontal-amygdala circuit and self-regulation of social-emotional behavior in autism
    • Bachevalier, J., and Loveland, K. A. (2006). The orbitofrontal-amygdala circuit and self-regulation of social-emotional behavior in autism. Neurosci. Biobehav. Rev. 30, 97-117. doi: 10.1016/j.neubiorev.2005.07.002.
    • (2006) Neurosci. Biobehav. Rev , vol.30 , pp. 97-117
    • Bachevalier, J.1    Loveland, K.A.2
  • 5
    • 0028906338 scopus 로고
    • Autism as a strongly genetic disorder: Evidence from a British twin study
    • Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., et al. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychol. Med. 25, 63-77. doi: 10.1017/S0033291700028099.
    • (1995) Psychol. Med , vol.25 , pp. 63-77
    • Bailey, A.1    Le Couteur, A.2    Gottesman, I.3    Bolton, P.4    Simonoff, E.5    Yuzda, E.6
  • 6
    • 80051491682 scopus 로고    scopus 로고
    • Animal model of autism induced by prenatal exposure to valproate: Behavioral changes and liver parameters
    • Bambini-Junior, V., Rodrigues, L., Behr, G. A., Moreira, J. C., Riesgo, R., and Gottfried, C. (2011). Animal model of autism induced by prenatal exposure to valproate: behavioral changes and liver parameters. Brain Res. 1408, 8-16. doi: 10.1016/j.brainres.2011.06.015.
    • (2011) Brain Res , vol.1408 , pp. 8-16
    • Bambini-Junior, V.1    Rodrigues, L.2    Behr, G.A.3    Moreira, J.C.4    Riesgo, R.5    Gottfried, C.6
  • 7
    • 33644938580 scopus 로고    scopus 로고
    • Individuals with autism spectrum disorder show normal responses to a fear potential startle paradigm
    • Bernier, R., Dawson, G., Panagiotides, H., and Webb, S. (2005). Individuals with autism spectrum disorder show normal responses to a fear potential startle paradigm. J. Autism Dev. Disord. 35, 575-583. doi: 10.1007/s10803-005-0002-0.
    • (2005) J. Autism Dev. Disord , vol.35 , pp. 575-583
    • Bernier, R.1    Dawson, G.2    Panagiotides, H.3    Webb, S.4
  • 8
    • 77957183374 scopus 로고
    • Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats
    • Binkerd, P. E., Rowland, J. M., Nau, H., and Hendrickx, A. G. (1988). Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats. Fundam. Appl. Toxicol. 11, 485-493. doi: 10.1016/0272-0590(88)90112-1.
    • (1988) Fundam. Appl. Toxicol , vol.11 , pp. 485-493
    • Binkerd, P.E.1    Rowland, J.M.2    Nau, H.3    Hendrickx, A.G.4
  • 9
    • 84902482281 scopus 로고    scopus 로고
    • Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex
    • Centanni, T. M., Booker, A. B., Sloan, A. M., Chen, F., Maher, B. J., Carraway, R. S., et al. (2014). Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex. Cereb. Cortex 24, 1753-1766. doi: 10.1093/cercor/bht028.
    • (2014) Cereb. Cortex , vol.24 , pp. 1753-1766
    • Centanni, T.M.1    Booker, A.B.2    Sloan, A.M.3    Chen, F.4    Maher, B.J.5    Carraway, R.S.6
  • 10
    • 79952314858 scopus 로고    scopus 로고
    • IQ in children with autism spectrum disorders: Data from the Special Needs and Autism Project (SNAP)
    • Charman, T., Pickles, A., Simonoff, E., Chandler, S., Loucas, T., and Baird, G. (2011). IQ in children with autism spectrum disorders: data from the Special Needs and Autism Project (SNAP). Psychol. Med. 41, 619-627. doi: 10.1017/S0033291710000991.
    • (2011) Psychol. Med , vol.41 , pp. 619-627
    • Charman, T.1    Pickles, A.2    Simonoff, E.3    Chandler, S.4    Loucas, T.5    Baird, G.6
  • 12
    • 84897519705 scopus 로고    scopus 로고
    • Auditory-cued sensorimotor task reveals disengagement deficits in rats exposed to the autism-associated teratogen valproic acid
    • Chomiak, T., Hung, J., Cihal, A., Dhaliwal, J., Baghdadwala, M. I., Dzwonek, A., et al. (2014). Auditory-cued sensorimotor task reveals disengagement deficits in rats exposed to the autism-associated teratogen valproic acid. Neuroscience 268, 212-220. doi: 10.1016/j.neuroscience.2014.02.049.
    • (2014) Neuroscience , vol.268 , pp. 212-220
    • Chomiak, T.1    Hung, J.2    Cihal, A.3    Dhaliwal, J.4    Baghdadwala, M.I.5    Dzwonek, A.6
  • 13
    • 0028220791 scopus 로고
    • Fetal valproate syndrome: Clinical and neuro-developmental features in two sibling pairs
    • Christianson, A. L., Chesler, N., and Kromberg, J. G. (1994). Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs. Dev. Med. Child Neurol. 36, 361-369. doi: 10.1111/j.1469-8749.1994.tb11858.x.
    • (1994) Dev. Med. Child Neurol , vol.36 , pp. 361-369
    • Christianson, A.L.1    Chesler, N.2    Kromberg, J.G.3
  • 14
    • 84885761570 scopus 로고    scopus 로고
    • Acute prenatal exposure to a moderate dose of valproic acid increases social behavior and alters gene expression in rats
    • Cohen, O. S., Varlinskaya, E. I., Wilson, C. A., Glatt, S. J., and Mooney, S. M. (2013). Acute prenatal exposure to a moderate dose of valproic acid increases social behavior and alters gene expression in rats. Int. J. Dev. Neurosci. 31, 740-750. doi: 10.1016/j.ijdevneu.2013.09.002.
    • (2013) Int. J. Dev. Neurosci , vol.31 , pp. 740-750
    • Cohen, O.S.1    Varlinskaya, E.I.2    Wilson, C.A.3    Glatt, S.J.4    Mooney, S.M.5
  • 15
    • 77955073408 scopus 로고    scopus 로고
    • Genetic and maternal effects on valproic acid teratogenesis in C57BL/6J and DBA/2J mice
    • Downing, C., Biers, J., Larson, C., Kimball, A., Wright, H., Ishii, T., et al. (2010). Genetic and maternal effects on valproic acid teratogenesis in C57BL/6J and DBA/2J mice. Toxicol. Sci. 116, 632-639. doi: 10.1093/toxsci/kfq140.
    • (2010) Toxicol. Sci , vol.116 , pp. 632-639
    • Downing, C.1    Biers, J.2    Larson, C.3    Kimball, A.4    Wright, H.5    Ishii, T.6
  • 16
    • 84880920223 scopus 로고    scopus 로고
    • Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism
    • Edalatmanesh, M. A., Nikfarjam, H., Vafaee, F., and Moghadas, M. (2013). Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism. Brain Res. 1526, 15-25. doi: 10.1016/j.brainres.2013.06.024.
    • (2013) Brain Res , vol.1526 , pp. 15-25
    • Edalatmanesh, M.A.1    Nikfarjam, H.2    Vafaee, F.3    Moghadas, M.4
  • 17
    • 84927570150 scopus 로고    scopus 로고
    • Degraded auditory processing in a rat model of autism limits the speech representation in non-primary auditory cortex
    • Engineer, C. T., Centanni, T. M., Im, K. W., Borland, M. S., Moreno, N. A., Carraway, R. S., et al. (2014a). Degraded auditory processing in a rat model of autism limits the speech representation in non-primary auditory cortex. Dev. Neurobiol. 74, 972-986. doi: 10.1002/dneu.22175.
    • (2014) Dev. Neurobiol , vol.74 , pp. 972-986
    • Engineer, C.T.1    Centanni, T.M.2    Im, K.W.3    Borland, M.S.4    Moreno, N.A.5    Carraway, R.S.6
  • 18
    • 84899920392 scopus 로고    scopus 로고
    • Degraded speech sound processing in a rat model of fragile X syndrome
    • Engineer, C. T., Centanni, T. M., Im, K. W., Rahebi, K. C., Buell, E. P., and Kilgard, M. P. (2014b). Degraded speech sound processing in a rat model of fragile X syndrome. Brain Res. 1564, 72-84. doi: 10.1016/j.brainres.2014.03.049.
    • (2014) Brain Res , vol.1564 , pp. 72-84
    • Engineer, C.T.1    Centanni, T.M.2    Im, K.W.3    Rahebi, K.C.4    Buell, E.P.5    Kilgard, M.P.6
  • 19
    • 23644450062 scopus 로고    scopus 로고
    • The fears, phobias and anxieties of children with autism spectrum disorders and Down syndrome: Comparisons with developmentally and chronologically age matched children
    • Evans, D. W., Canavera, K., Kleinpeter, F. L., Maccubbin, E., and Taga, K. (2005). The fears, phobias and anxieties of children with autism spectrum disorders and Down syndrome: comparisons with developmentally and chronologically age matched children. Child Psychiatry Hum. Dev. 36, 3-26. doi: 10.1007/s10578-004-3619-x.
    • (2005) Child Psychiatry Hum. Dev , vol.36 , pp. 3-26
    • Evans, D.W.1    Canavera, K.2    Kleinpeter, F.L.3    Maccubbin, E.4    Taga, K.5
  • 20
    • 3042859183 scopus 로고    scopus 로고
    • The activity of antiepileptic drugs as histone deacetylase inhibitors
    • Eyal, S., Yagen, B., Sobol, E., Altschuler, Y., Shmuel, M., and Bialer, M. (2004). The activity of antiepileptic drugs as histone deacetylase inhibitors. Epilepsia 45, 737-744. doi: 10.1111/j.0013-9580.2004.00104.x.
    • (2004) Epilepsia , vol.45 , pp. 737-744
    • Eyal, S.1    Yagen, B.2    Sobol, E.3    Altschuler, Y.4    Shmuel, M.5    Bialer, M.6
  • 22
    • 52049126390 scopus 로고    scopus 로고
    • Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors
    • Fernandez, S. M., Lewis, M. C., Pechenino, A. S., Harburger, L. L., Orr, P. T., Gresack, J. E., et al. (2008). Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors. J. Neurosci. 28, 8660-8667. doi: 10.1523/JNEUROSCI.1968-08.2008.
    • (2008) J. Neurosci , vol.28 , pp. 8660-8667
    • Fernandez, S.M.1    Lewis, M.C.2    Pechenino, A.S.3    Harburger, L.L.4    Orr, P.T.5    Gresack, J.E.6
  • 23
    • 0346995345 scopus 로고    scopus 로고
    • Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice
    • Frick, K. M., and Gresack, J. E. (2003). Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice. Behav. Neurosci. 117, 1283-1291. doi: 10.1037/0735-7044.117.6.1283.
    • (2003) Behav. Neurosci , vol.117 , pp. 1283-1291
    • Frick, K.M.1    Gresack, J.E.2
  • 24
    • 66849138564 scopus 로고    scopus 로고
    • Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat
    • Frisch, C., Husch, K., Angenstein, F., Kudin, A., Kunz, W., Elger, C. E., et al. (2009). Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat. Epilepsia 50, 1432-1441. doi: 10.1111/j.1528-1167.2008.01943.x.
    • (2009) Epilepsia , vol.50 , pp. 1432-1441
    • Frisch, C.1    Husch, K.2    Angenstein, F.3    Kudin, A.4    Kunz, W.5    Elger, C.E.6
  • 25
    • 34247512211 scopus 로고    scopus 로고
    • Differential fear conditioning in Asperger's syndrome: Implications for an amygdala theory of autism
    • Gaigg, S. B., and Bowler, D. M. (2007). Differential fear conditioning in Asperger's syndrome: implications for an amygdala theory of autism. Neuropsychologia 45, 2125-2134. doi: 10.1016/j.neuropsychologia.2007.01.012.
    • (2007) Neuropsychologia , vol.45 , pp. 2125-2134
    • Gaigg, S.B.1    Bowler, D.M.2
  • 26
    • 80053589736 scopus 로고    scopus 로고
    • A standardized protocol for repeated social defeat stress in mice
    • Golden, S. A., Covington, H. E. 3rd., Berton, O., and Russo, S. J. (2011). A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 6, 1183-1191. doi: 10.1038/nprot.2011.361.
    • (2011) Nat. Protoc , vol.6 , pp. 1183-1191
    • Golden, S.A.1    Covington, H.E.2    Berton, O.3    Russo, S.J.4
  • 27
    • 4243196940 scopus 로고    scopus 로고
    • Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers
    • Gould, T. D., Quiroz, J. A., Singh, J., Zarate, C. A., and Manji, H. K. (2004). Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Mol. Psychiatry 9, 734-755. doi: 10.1038/sj.mp.4001518.
    • (2004) Mol. Psychiatry , vol.9 , pp. 734-755
    • Gould, T.D.1    Quiroz, J.A.2    Singh, J.3    Zarate, C.A.4    Manji, H.K.5
  • 28
    • 84886088928 scopus 로고    scopus 로고
    • Social instability stress in adolescence increases anxiety and reduces social interactions in adulthood in male Long-Evans rats
    • Green, M. R., Barnes, B., and Mccormick, C. M. (2013a). Social instability stress in adolescence increases anxiety and reduces social interactions in adulthood in male Long-Evans rats. Dev. Psychobiol. 55, 849-859. doi: 10.1002/dev.21077.
    • (2013) Dev. Psychobiol , vol.55 , pp. 849-859
    • Green, M.R.1    Barnes, B.2    McCormick, C.M.3
  • 30
    • 57749170458 scopus 로고    scopus 로고
    • The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
    • Haberland, M., Montgomery, R. L., and Olson, E. N. (2009). The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet. 10, 32-42. doi: 10.1038/nrg2485.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 32-42
    • Haberland, M.1    Montgomery, R.L.2    Olson, E.N.3
  • 31
    • 80051944739 scopus 로고    scopus 로고
    • Genetic heritability and shared environmental factors among twin pairs with autism
    • Hallmayer, J., Cleveland, S., Torres, A., Phillips, J., Cohen, B., Torigoe, T., et al. (2011). Genetic heritability and shared environmental factors among twin pairs with autism. Arch. Gen. Psychiatry 68, 1095-1102. doi: 10.1001/archgenpsychiatry.2011.76.
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 1095-1102
    • Hallmayer, J.1    Cleveland, S.2    Torres, A.3    Phillips, J.4    Cohen, B.5    Torigoe, T.6
  • 32
    • 0034612151 scopus 로고    scopus 로고
    • Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism
    • Ingram, J. L., Peckham, S. M., Tisdale, B., and Rodier, P. M. (2000). Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. Neurotoxicol. Teratol. 22, 319-324. doi: 10.1016/S0892-0362(99)00083-5.
    • (2000) Neurotoxicol. Teratol , vol.22 , pp. 319-324
    • Ingram, J.L.1    Peckham, S.M.2    Tisdale, B.3    Rodier, P.M.4
  • 33
    • 61349131471 scopus 로고    scopus 로고
    • Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects
    • Jergil, M., Kultima, K., Gustafson, A. L., Dencker, L., and Stigson, M. (2009). Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects. Toxicol. Sci. 108, 132-148. doi: 10.1093/toxsci/kfp002.
    • (2009) Toxicol. Sci , vol.108 , pp. 132-148
    • Jergil, M.1    Kultima, K.2    Gustafson, A.L.3    Dencker, L.4    Stigson, M.5
  • 34
    • 84871490248 scopus 로고    scopus 로고
    • Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid
    • Kataoka, S., Takuma, K., Hara, Y., Maeda, Y., Ago, Y., and Matsuda, T. (2013). Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid. Int. J. Neuropsychopharmacol. 16, 91-103. doi: 10.1017/S1461145711001714.
    • (2013) Int. J. Neuropsychopharmacol , vol.16 , pp. 91-103
    • Kataoka, S.1    Takuma, K.2    Hara, Y.3    Maeda, Y.4    Ago, Y.5    Matsuda, T.6
  • 35
    • 0031812364 scopus 로고    scopus 로고
    • Neuropathology of infantile autism
    • Kemper, T. L., and Bauman, M. (1998). Neuropathology of infantile autism. J. Neuropathol. Exp. Neurol. 57, 645-652. doi: 10.1097/00005072-199807000-00001.
    • (1998) J. Neuropathol. Exp. Neurol , vol.57 , pp. 645-652
    • Kemper, T.L.1    Bauman, M.2
  • 36
    • 84878136965 scopus 로고    scopus 로고
    • Alterations in the endocannabinoid system in the rat valproic acid model of autism
    • Kerr, D. M., Downey, L., Conboy, M., Finn, D. P., and Roche, M. (2013). Alterations in the endocannabinoid system in the rat valproic acid model of autism. Behav. Brain Res. 249, 124-132. doi: 10.1016/j.bbr.2013.04.043.
    • (2013) Behav. Brain Res , vol.249 , pp. 124-132
    • Kerr, D.M.1    Downey, L.2    Conboy, M.3    Finn, D.P.4    Roche, M.5
  • 37
    • 0032867215 scopus 로고    scopus 로고
    • Distributed representation of spectral and temporal information in rat primary auditory cortex
    • Kilgard, M. P., and Merzenich, M. M. (1999). Distributed representation of spectral and temporal information in rat primary auditory cortex. Hear. Res. 134, 16-28. doi: 10.1016/S0378-5955(99)00061-1.
    • (1999) Hear. Res , vol.134 , pp. 16-28
    • Kilgard, M.P.1    Merzenich, M.M.2
  • 38
    • 79651474341 scopus 로고    scopus 로고
    • The critical period of valproate exposure to induce autistic symptoms in Sprague-Dawley rats
    • Kim, K. C., Kim, P., Go, H. S., Choi, C. S., Yang, S. I., Cheong, J. H., et al. (2011). The critical period of valproate exposure to induce autistic symptoms in Sprague-Dawley rats. Toxicol. Lett. 201, 137-142. doi: 10.1016/j.toxlet.2010.12.018.
    • (2011) Toxicol. Lett , vol.201 , pp. 137-142
    • Kim, K.C.1    Kim, P.2    Go, H.S.3    Choi, C.S.4    Yang, S.I.5    Cheong, J.H.6
  • 39
    • 77956442714 scopus 로고    scopus 로고
    • Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity
    • Kultima, K., Jergil, M., Salter, H., Gustafson, A. L., Dencker, L., and Stigson, M. (2010). Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity. Reprod. Toxicol. 30, 457-468. doi: 10.1016/j.reprotox.2010.05.014.
    • (2010) Reprod. Toxicol , vol.30 , pp. 457-468
    • Kultima, K.1    Jergil, M.2    Salter, H.3    Gustafson, A.L.4    Dencker, L.5    Stigson, M.6
  • 40
    • 0034935392 scopus 로고    scopus 로고
    • The mechanisms of action of commonly used antiepileptic drugs
    • Kwan, P., Sills, G. J., and Brodie, M. J. (2001). The mechanisms of action of commonly used antiepileptic drugs. Pharmacol. Ther. 90, 21-34. doi: 10.1016/S0163-7258(01)00122-X.
    • (2001) Pharmacol. Ther , vol.90 , pp. 21-34
    • Kwan, P.1    Sills, G.J.2    Brodie, M.J.3
  • 41
    • 84875155821 scopus 로고    scopus 로고
    • Improving basic and translational science by accounting for litter-to-litter variation in animal models
    • Lazic, S. E., and Essioux, L. (2013). Improving basic and translational science by accounting for litter-to-litter variation in animal models. BMC Neurosci. 14:37. doi: 10.1186/1471-2202-14-37.
    • (2013) BMC Neurosci , vol.14 , pp. 37
    • Lazic, S.E.1    Essioux, L.2
  • 42
    • 84873832901 scopus 로고    scopus 로고
    • The amygdala excitatory/inhibitory balance in a valproate-induced rat autism model
    • Lin, H. C., Gean, P. W., Wang, C. C., Chan, Y. H., and Chen, P. S. (2013). The amygdala excitatory/inhibitory balance in a valproate-induced rat autism model. PLoS ONE 8:e55248. doi: 10.1371/journal.pone.0055248.
    • (2013) PLoS ONE , vol.8
    • Lin, H.C.1    Gean, P.W.2    Wang, C.C.3    Chan, Y.H.4    Chen, P.S.5
  • 43
    • 77949375239 scopus 로고    scopus 로고
    • Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons
    • Mao, R., Page, D. T., Merzlyak, I., Kim, C., Tecott, L. H., Janak, P. H., et al. (2009). Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons. J. Neurodev. Disord. 1, 224-236. doi: 10.1007/s11689-009-9025-8.
    • (2009) J. Neurodev. Disord , vol.1 , pp. 224-236
    • Mao, R.1    Page, D.T.2    Merzlyak, I.3    Kim, C.4    Tecott, L.H.5    Janak, P.H.6
  • 44
    • 39149089652 scopus 로고    scopus 로고
    • Abnormal fear conditioning and amygdala processing in an animal model of autism
    • Markram, K., Rinaldi, T., La Mendola, D., Sandi, C., and Markram, H. (2008). Abnormal fear conditioning and amygdala processing in an animal model of autism. Neuropsychopharmacology 33, 901-912. doi: 10.1038/sj.npp.1301453.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 901-912
    • Markram, K.1    Rinaldi, T.2    La Mendola, D.3    Sandi, C.4    Markram, H.5
  • 45
    • 40749089626 scopus 로고    scopus 로고
    • Structural variation of chromosomes in autism spectrum disorder
    • Marshall, C. R., Noor, A., Vincent, J. B., Lionel, A. C., Feuk, L., Skaug, J., et al. (2008). Structural variation of chromosomes in autism spectrum disorder. Am. J. Hum. Genet. 82, 477-488. doi: 10.1016/j.ajhg.2007.12.009.
    • (2008) Am. J. Hum. Genet , vol.82 , pp. 477-488
    • Marshall, C.R.1    Noor, A.2    Vincent, J.B.3    Lionel, A.C.4    Feuk, L.5    Skaug, J.6
  • 46
    • 84928153724 scopus 로고    scopus 로고
    • Late onset deficits in synaptic plasticity in the valproic acid rat model of autism
    • Martin, H. G., and Manzoni, O. J. (2014). Late onset deficits in synaptic plasticity in the valproic acid rat model of autism. Front. Cell. Neurosci. 8:23. doi: 10.3389/fncel.2014.00023.
    • (2014) Front. Cell. Neurosci , vol.8 , pp. 23
    • Martin, H.G.1    Manzoni, O.J.2
  • 47
    • 0033868288 scopus 로고    scopus 로고
    • The external validity of Asperger disorder: Lack of evidence from the domain of neuropsychology
    • Miller, J. N., and Ozonoff, S. (2000). The external validity of Asperger disorder: lack of evidence from the domain of neuropsychology. J. Abnorm. Psychol. 109, 227-238. doi: 10.1037/0021-843X.109.2.227.
    • (2000) J. Abnorm. Psychol , vol.109 , pp. 227-238
    • Miller, J.N.1    Ozonoff, S.2
  • 48
    • 84886404961 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice
    • Moldrich, R. X., Leanage, G., She, D., Dolan-Evans, E., Nelson, M., Reza, N., et al. (2013). Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice. Behav. Brain Res. 257, 253-264. doi: 10.1016/j.bbr.2013.09.049.
    • (2013) Behav. Brain Res , vol.257 , pp. 253-264
    • Moldrich, R.X.1    Leanage, G.2    She, D.3    Dolan-Evans, E.4    Nelson, M.5    Reza, N.6
  • 49
    • 66049101024 scopus 로고    scopus 로고
    • Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
    • Montgomery, R. L., Hsieh, J., Barbosa, A. C., Richardson, J. A., and Olson, E. N. (2009). Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc. Natl. Acad. Sci. U.S.A. 106, 7876-7881. doi: 10.1073/pnas.0902750106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A , vol.106 , pp. 7876-7881
    • Montgomery, R.L.1    Hsieh, J.2    Barbosa, A.C.3    Richardson, J.A.4    Olson, E.N.5
  • 50
    • 0033934755 scopus 로고    scopus 로고
    • A clinical study of 57 children with fetal anticonvulsant syndromes
    • Moore, S. J., Turnpenny, P., Quinn, A., Glover, S., Lloyd, D. J., Montgomery, T., et al. (2000). A clinical study of 57 children with fetal anticonvulsant syndromes. J. Med. Genet. 37, 489-497. doi: 10.1136/jmg.37.7.489.
    • (2000) J. Med. Genet , vol.37 , pp. 489-497
    • Moore, S.J.1    Turnpenny, P.2    Quinn, A.3    Glover, S.4    Lloyd, D.J.5    Montgomery, T.6
  • 51
    • 56649098806 scopus 로고    scopus 로고
    • Evidence for latent classes of IQ in young children with autism spectrum disorder
    • Munson, J., Dawson, G., Sterling, L., Beauchaine, T., Zhou, A., Elizabeth, K., et al. (2008). Evidence for latent classes of IQ in young children with autism spectrum disorder. Am. J. Ment. Retard. 113, 439-452. doi: 10.1352/2008.113:439-452.
    • (2008) Am. J. Ment. Retard , vol.113 , pp. 439-452
    • Munson, J.1    Dawson, G.2    Sterling, L.3    Beauchaine, T.4    Zhou, A.5    Elizabeth, K.6
  • 52
    • 35348974094 scopus 로고    scopus 로고
    • Valproate-induced developmental neurotoxicity is affected by maternal conditions including shipping stress and environmental change during early pregnancy
    • Ogawa, T., Kuwagata, M., Hori, Y., and Shioda, S. (2007). Valproate-induced developmental neurotoxicity is affected by maternal conditions including shipping stress and environmental change during early pregnancy. Toxicol. Lett. 174, 18-24. doi: 10.1016/j.toxlet.2007.08.006.
    • (2007) Toxicol. Lett , vol.174 , pp. 18-24
    • Ogawa, T.1    Kuwagata, M.2    Hori, Y.3    Shioda, S.4
  • 53
    • 84877789398 scopus 로고    scopus 로고
    • Comparative gene expression analysis of the amygdala in autistic rat models produced by pre-and post-natal exposures to valproic acid
    • Oguchi-Katayama, A., Monma, A., Sekino, Y., Moriguchi, T., and Sato, K. (2013). Comparative gene expression analysis of the amygdala in autistic rat models produced by pre-and post-natal exposures to valproic acid. J. Toxicol. Sci. 38, 391-402. doi: 10.2131/jts.38.391.
    • (2013) J. Toxicol. Sci , vol.38 , pp. 391-402
    • Oguchi-Katayama, A.1    Monma, A.2    Sekino, Y.3    Moriguchi, T.4    Sato, K.5
  • 55
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel, C. J., Zhang, F., Huang, E. Y., Guenther, M. G., Lazar, M. A., and Klein, P. S. (2001). Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J. Biol. Chem. 276, 36734-36741. doi: 10.1074/jbc.M101287200.
    • (2001) J. Biol. Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 56
    • 34447323087 scopus 로고    scopus 로고
    • Multiparametric auditory receptive field organization across five cortical fields in the albino rat
    • Polley, D. B., Read, H. L., Storace, D. A., and Merzenich, M. M. (2007). Multiparametric auditory receptive field organization across five cortical fields in the albino rat. J. Neurophysiol. 97, 3621-3638. doi: 10.1152/jn.01298.2006.
    • (2007) J. Neurophysiol , vol.97 , pp. 3621-3638
    • Polley, D.B.1    Read, H.L.2    Storace, D.A.3    Merzenich, M.M.4
  • 58
    • 0031104734 scopus 로고    scopus 로고
    • Linking etiologies in humans and animal models: Studies of autism
    • Rodier, P. M., Ingram, J. L., Tisdale, B., and Croog, V. J. (1997). Linking etiologies in humans and animal models: studies of autism. Reprod. Toxicol. 11, 417-422. doi: 10.1016/S0890-6238(97)80001-U.
    • (1997) Reprod. Toxicol , vol.11 , pp. 417-422
    • Rodier, P.M.1    Ingram, J.L.2    Tisdale, B.3    Croog, V.J.4
  • 59
    • 0029990539 scopus 로고    scopus 로고
    • Embryological origin for autism: Developmental anomalies of the cranial nerve motor nuclei
    • Rodier, P. M., Ingram, J. L., Tisdale, B., Nelson, S., and Romano, J. (1996). Embryological origin for autism: developmental anomalies of the cranial nerve motor nuclei. J. Comp. Neurol. 370, 247-261.
    • (1996) J. Comp. Neurol , vol.370 , pp. 247-261
    • Rodier, P.M.1    Ingram, J.L.2    Tisdale, B.3    Nelson, S.4    Romano, J.5
  • 60
    • 11144259318 scopus 로고    scopus 로고
    • Behavioral alterations in rats prenatally exposed to valproic acid: Animal model of autism
    • Schneider, T., and Przewlocki, R. (2005). Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism. Neuropsychopharmacology 30, 80-89. doi: 10.1038/sj.npp.1300518.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 80-89
    • Schneider, T.1    Przewlocki, R.2
  • 61
    • 46249109052 scopus 로고    scopus 로고
    • Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid
    • Schneider, T., Roman, A., Basta-Kaim, A., Kubera, M., Budziszewska, B., Schneider, K., et al. (2008). Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid. Psychoneuroendocrinology 33, 728-740. doi: 10.1016/j.psyneuen.2008.02.011.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 728-740
    • Schneider, T.1    Roman, A.2    Basta-Kaim, A.3    Kubera, M.4    Budziszewska, B.5    Schneider, K.6
  • 62
    • 34447626496 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism
    • Schneider, T., Ziolkowska, B., Gieryk, A., Tyminska, A., and Przewlocki, R. (2007). Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism. Psychopharmacology (Berl) 193, 547-555. doi: 10.1007/s00213-007-0795-y.
    • (2007) Psychopharmacology (Berl) , vol.193 , pp. 547-555
    • Schneider, T.1    Ziolkowska, B.2    Gieryk, A.3    Tyminska, A.4    Przewlocki, R.5
  • 63
    • 14644396233 scopus 로고    scopus 로고
    • Developmental deficits in social perception in autism: The role of the amygdala and fusiform face area
    • Schultz, R. T. (2005). Developmental deficits in social perception in autism: the role of the amygdala and fusiform face area. Int. J. Dev. Neurosci. 23, 125-141. doi: 10.1016/j.ijdevneu.2004.12.012.
    • (2005) Int. J. Dev. Neurosci , vol.23 , pp. 125-141
    • Schultz, R.T.1
  • 64
    • 50549086376 scopus 로고    scopus 로고
    • Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling
    • Shaked, M., Weissmuller, K., Svoboda, H., Hortschansky, P., Nishino, N., Wolfl, S., et al. (2008). Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling. PLoS ONE 3:e2668. doi: 10.1371/journal.pone.0002668.
    • (2008) PLoS ONE , vol.3
    • Shaked, M.1    Weissmuller, K.2    Svoboda, H.3    Hortschansky, P.4    Nishino, N.5    Wolfl, S.6
  • 65
    • 83355175804 scopus 로고    scopus 로고
    • Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders
    • South, M., Larson, M. J., White, S. E., Dana, J., and Crowley, M. J. (2011). Better fear conditioning is associated with reduced symptom severity in autism spectrum disorders. Autism Res. 4, 412-421. doi: 10.1002/aur.221.
    • (2011) Autism Res , vol.4 , pp. 412-421
    • South, M.1    Larson, M.J.2    White, S.E.3    Dana, J.4    Crowley, M.J.5
  • 66
    • 84871435749 scopus 로고    scopus 로고
    • Delayed reversal learning and association with repetitive behavior in autism spectrum disorders
    • South, M., Newton, T., and Chamberlain, P. D. (2012). Delayed reversal learning and association with repetitive behavior in autism spectrum disorders. Autism Res. 5, 398-406. doi: 10.1002/aur.1255.
    • (2012) Autism Res , vol.5 , pp. 398-406
    • South, M.1    Newton, T.2    Chamberlain, P.D.3
  • 67
    • 84862810515 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories
    • Sui, L., and Chen, M. (2012). Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories. Brain Res. Bull. 87, 556-563. doi: 10.1016/j.brainresbull.2012.01.011.
    • (2012) Brain Res. Bull , vol.87 , pp. 556-563
    • Sui, L.1    Chen, M.2
  • 69
    • 7444266950 scopus 로고    scopus 로고
    • Critical relationship between sodium valproate dose and human teratogenicity: Results of the Australian register of anti-epileptic drugs in pregnancy
    • Vajda, F. J., O'brien, T. J., Hitchcock, A., Graham, J., Cook, M., Lander, C., et al. (2004). Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy. J. Clin. Neurosci. 11, 854-858. doi: 10.1016/j.jocn.2004.05.003.
    • (2004) J. Clin. Neurosci , vol.11 , pp. 854-858
    • Vajda, F.J.1    O'brien, T.J.2    Hitchcock, A.3    Graham, J.4    Cook, M.5    Lander, C.6
  • 70
    • 0023257580 scopus 로고
    • Behavioral teratogenicity of valproic acid: Selective effects on behavior after prenatal exposure to rats
    • Vorhees, C. V. (1987). Behavioral teratogenicity of valproic acid: selective effects on behavior after prenatal exposure to rats. Psychopharmacology (Berl) 92, 173-179. doi: 10.1007/BF00177911.
    • (1987) Psychopharmacology (Berl) , vol.92 , pp. 173-179
    • Vorhees, C.V.1
  • 71
    • 84883428397 scopus 로고    scopus 로고
    • 5-HT1A-receptor agonist modified amygdala activity and amygdala-associated social behavior in a valproate-induced rat autism model
    • Wang, C. C., Lin, H. C., Chan, Y. H., Gean, P. W., Yang, Y. K., and Chen, P. S. (2013). 5-HT1A-receptor agonist modified amygdala activity and amygdala-associated social behavior in a valproate-induced rat autism model. Int. J. Neuropsychopharmacol. 16, 2027-2039. doi: 10.1017/S1461145713000473.
    • (2013) Int. J. Neuropsychopharmacol , vol.16 , pp. 2027-2039
    • Wang, C.C.1    Lin, H.C.2    Chan, Y.H.3    Gean, P.W.4    Yang, Y.K.5    Chen, P.S.6
  • 72
    • 23944472097 scopus 로고    scopus 로고
    • The presentation of anxiety in children with pervasive developmental disorders
    • Weisbrot, D. M., Gadow, K. D., Devincent, C. J., and Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 15, 477-496. doi: 10.1089/cap.2005.15.477.
    • (2005) J. Child Adolesc. Psychopharmacol , vol.15 , pp. 477-496
    • Weisbrot, D.M.1    Gadow, K.D.2    Devincent, C.J.3    Pomeroy, J.4
  • 73
    • 84879026339 scopus 로고    scopus 로고
    • An evaluation of multi-component exposure treatment of needle phobia in an adult with autism and intellectual disability
    • Wolff, J. J., and Symons, F. J. (2013). An evaluation of multi-component exposure treatment of needle phobia in an adult with autism and intellectual disability. J. Appl. Res. Intellect. Disabil. 26, 344-348. doi: 10.1111/jar.12002.
    • (2013) J. Appl. Res. Intellect. Disabil , vol.26 , pp. 344-348
    • Wolff, J.J.1    Symons, F.J.2
  • 74
    • 23744492534 scopus 로고    scopus 로고
    • Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome
    • Zhao, M. G., Toyoda, H., Ko, S. W., Ding, H. K., Wu, L. J., and Zhuo, M. (2005). Deficits in trace fear memory and long-term potentiation in a mouse model for fragile X syndrome. J. Neurosci. 25, 7385-7392. doi: 10.1523/JNEUROSCI.1520-05.2005.
    • (2005) J. Neurosci , vol.25 , pp. 7385-7392
    • Zhao, M.G.1    Toyoda, H.2    Ko, S.W.3    Ding, H.K.4    Wu, L.J.5    Zhuo, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.