메뉴 건너뛰기




Volumn , Issue JUL, 2013, Pages

General developmental health in the VPA-rat model of autism

Author keywords

Animal model; Autism; Development; Rat; Teratogen; Valproic acid; VPA

Indexed keywords

VALPROIC ACID;

EID: 84879701809     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2013.00088     Document Type: Article
Times cited : (97)

References (101)
  • 2
    • 80051491682 scopus 로고    scopus 로고
    • Animal model of autism induced by prenatal exposure to valproate: Behavioral changes and liver parameters
    • Bambini-Junior, V., Rodrigues, L., Behr, G. A., Moreira, J. C., Riesgo, R. and Gottfried, C. (2011). "Animal model of autism induced by prenatal exposure to valproate: Behavioral changes and liver parameters. " Brain Res 1408: 8-16.
    • (2011) Brain Res , vol.1408 , pp. 8-16
    • Bambini-Junior, V.1    Rodrigues, L.2    Behr, G.A.3    Moreira, J.C.4    Riesgo, R.5    Gottfried, C.6
  • 3
    • 0038699285 scopus 로고    scopus 로고
    • Autism and mobius sequence: An exploratory study of children in northeastern brazil
    • Bandim, J. M., Ventura, L. O., Miller, M. T., Almeida, H. C. and Costa, A. E. (2003). "Autism and mobius sequence: An exploratory study of children in northeastern brazil. " Arq Neuropsiquiatr 61(2A): 181-185.
    • (2003) Arq Neuropsiquiatr , vol.61 , Issue.2 A , pp. 181-185
    • Bandim, J.M.1    Ventura, L.O.2    Miller, M.T.3    Almeida, H.C.4    Costa, A.E.5
  • 4
    • 33644938580 scopus 로고    scopus 로고
    • Individuals with autism spectrum disorder show normal responses to a fear potential startle paradigm
    • Bernier, R., Dawson, G., Panagiotides, H. and Webb, S. (2005). "Individuals with autism spectrum disorder show normal responses to a fear potential startle paradigm. " J Autism Dev Disord 35(5): 575-583.
    • (2005) J Autism Dev Disord , vol.35 , Issue.5 , pp. 575-583
    • Bernier, R.1    Dawson, G.2    Panagiotides, H.3    Webb, S.4
  • 5
    • 79952313620 scopus 로고    scopus 로고
    • Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting
    • Betancur, C. (2011). "Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting. " Brain Res 1380: 42-77.
    • (2011) Brain Res , vol.1380 , pp. 42-77
    • Betancur, C.1
  • 6
    • 77957183374 scopus 로고
    • Evaluation of valproic acid (vpa) developmental toxicity and pharmacokinetics in sprague-dawley rats
    • Binkerd, P. E., Rowland, J. M., Nau, H. and Hendrickx, A. G. (1988). "Evaluation of valproic acid (vpa) developmental toxicity and pharmacokinetics in sprague-dawley rats. " Fundam Appl Toxicol 11(3): 485-493.
    • (1988) Fundam Appl Toxicol , vol.11 , Issue.3 , pp. 485-493
    • Binkerd, P.E.1    Rowland, J.M.2    Nau, H.3    Hendrickx, A.G.4
  • 7
    • 33646824434 scopus 로고    scopus 로고
    • Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare, and handleability: A cross-laboratory study
    • Burn, C. C., Peters, A., Day, M. J. and Mason, G. J. (2006). "Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare, and handleability: A cross-laboratory study. " Lab Anim 40(4): 353-370.
    • (2006) Lab Anim , vol.40 , Issue.4 , pp. 353-370
    • Burn, C.C.1    Peters, A.2    Day, M.J.3    Mason, G.J.4
  • 8
    • 35148841101 scopus 로고    scopus 로고
    • The neuropathology of autism
    • Casanova, M. F. (2007). "The neuropathology of autism. " Brain Pathol 17(4): 422-433.
    • (2007) Brain Pathol , vol.17 , Issue.4 , pp. 422-433
    • Casanova, M.F.1
  • 9
    • 70349453570 scopus 로고    scopus 로고
    • The impact of light, noise, cage cleaning and in-house transport on welfare and stress of laboratory rats
    • Castelhano-Carlos, M. J. and Baumans, V. (2009). "The impact of light, noise, cage cleaning and in-house transport on welfare and stress of laboratory rats. " Laboratory Animals 43(4): 311-327.
    • (2009) Laboratory Animals , vol.43 , Issue.4 , pp. 311-327
    • Castelhano-Carlos, M.J.1    Baumans, V.2
  • 10
    • 0021194157 scopus 로고
    • Sodium valproate: Effects on social behaviour and physical development in the mouse
    • Chapman, J. B. and Cutler, M. G. (1984). "Sodium valproate: Effects on social behaviour and physical development in the mouse. " Psychopharmacology (Berl) 83(4): 390-396.
    • (1984) Psychopharmacology (Berl) , vol.83 , Issue.4 , pp. 390-396
    • Chapman, J.B.1    Cutler, M.G.2
  • 11
    • 0014970976 scopus 로고
    • Autism in children with congenital rubella
    • Chess, S. (1971). "Autism in children with congenital rubella. " J Autism Child Schizophr 1(1): 33-47.
    • (1971) J Autism Child Schizophr , vol.1 , Issue.1 , pp. 33-47
    • Chess, S.1
  • 12
    • 84879724601 scopus 로고    scopus 로고
    • Alterations of neocortical development and maturation in autism: Insight from valproic acid exposure and animal models of autism
    • Chomiak, T. and Hu, B. (2012). "Alterations of neocortical development and maturation in autism: Insight from valproic acid exposure and animal models of autism. " Neurotoxicol Teratol.
    • (2012) Neurotoxicol Teratol
    • Chomiak, T.1    Hu, B.2
  • 13
    • 77955669611 scopus 로고    scopus 로고
    • Altering the trajectory of early postnatal cortical development can lead to structural and behavioural features of autism
    • Chomiak, T., Karnik, V., Block, E. and Hu, B. (2010). "Altering the trajectory of early postnatal cortical development can lead to structural and behavioural features of autism. " BMC Neurosci 11: 102.
    • (2010) BMC Neurosci , vol.11 , pp. 102
    • Chomiak, T.1    Karnik, V.2    Block, E.3    Hu, B.4
  • 15
    • 0029087724 scopus 로고
    • Fetal valproate syndrome
    • Clayton-Smith, J. and Donnai, D. (1995). "Fetal valproate syndrome. " J Med Genet 32(9): 724-727.
    • (1995) J Med Genet , vol.32 , Issue.9 , pp. 724-727
    • Clayton-Smith, J.1    Donnai, D.2
  • 16
    • 79952313504 scopus 로고    scopus 로고
    • Brain growth across the life span in autism: Age-specific changes in anatomical pathology
    • Courchesne, E., Campbell, K. and Solso, S. (2011). "Brain growth across the life span in autism: Age-specific changes in anatomical pathology. " Brain Res 1380: 138-145.
    • (2011) Brain Res , vol.1380 , pp. 138-145
    • Courchesne, E.1    Campbell, K.2    Solso, S.3
  • 17
    • 79953699287 scopus 로고    scopus 로고
    • Harderian gland of wistar rats revised as a protoporphyrin ix producer
    • dos Reis, E. R., Nicola, E. M. D. and Nicola, J. H. (2005). "Harderian gland of wistar rats revised as a protoporphyrin ix producer. " Braz. J. morphol. Sci 22(1): 43-51.
    • (2005) Braz. J. morphol. Sci , vol.22 , Issue.1 , pp. 43-51
    • dos Reis, E.R.1    Nicola, E.M.D.2    Nicola, J.H.3
  • 19
    • 77955475711 scopus 로고    scopus 로고
    • Feeding symptoms, dietary patterns, and growth in young children with autism spectrum disorders
    • Emond, A., Emmett, P., Steer, C. and Golding, J. (2010). "Feeding symptoms, dietary patterns, and growth in young children with autism spectrum disorders. " Pediatrics 126(2): e337-342.
    • (2010) Pediatrics , vol.126 , Issue.2
    • Emond, A.1    Emmett, P.2    Steer, C.3    Golding, J.4
  • 20
    • 23644450062 scopus 로고    scopus 로고
    • The fears, phobias and anxieties of children with autism spectrum disorders and down syndrome: Comparisons with developmentally and chronologically age matched children
    • Evans, D. W., Canavera, K., Kleinpeter, F. L., Maccubbin, E. and Taga, K. (2005). "The fears, phobias and anxieties of children with autism spectrum disorders and down syndrome: Comparisons with developmentally and chronologically age matched children. " Child Psychiatry Hum Dev 36(1): 3-26.
    • (2005) Child Psychiatry Hum Dev , vol.36 , Issue.1 , pp. 3-26
    • Evans, D.W.1    Canavera, K.2    Kleinpeter, F.L.3    McCubbin, E.4    Taga, K.5
  • 22
    • 84863613962 scopus 로고    scopus 로고
    • Class i histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder
    • Foley, A. G., Gannon, S., Rombach-Mullan, N., Prendergast, A., Barry, C., Cassidy, A. W. and Regan, C. M. (2012). "Class i histone deacetylase inhibition ameliorates social cognition and cell adhesion molecule plasticity deficits in a rodent model of autism spectrum disorder. " Neuropharmacology 63(4): 750-760.
    • (2012) Neuropharmacology , vol.63 , Issue.4 , pp. 750-760
    • Foley, A.G.1    Gannon, S.2    Rombach-Mullan, N.3    Prendergast, A.4    Barry, C.5    Cassidy, A.W.6    Regan, C.M.7
  • 23
    • 84878001307 scopus 로고    scopus 로고
    • The involvement of reelin in neurodevelopmental disorders
    • Folsom, T. D. and Hossein Fatemi, S. (2012). "The involvement of reelin in neurodevelopmental disorders. " Neuropharmacology.
    • (2012) Neuropharmacology
    • Folsom, T.D.1    Hossein Fatemi, S.2
  • 24
    • 67049118065 scopus 로고    scopus 로고
    • Epidemiology of pervasive developmental disorders
    • Fombonne, E. (2009). "Epidemiology of pervasive developmental disorders. " Pediatr Res 65(6): 591-598.
    • (2009) Pediatr Res , vol.65 , Issue.6 , pp. 591-598
    • Fombonne, E.1
  • 25
    • 66849138564 scopus 로고    scopus 로고
    • Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat
    • Frisch, C., Husch, K., Angenstein, F., Kudin, A., Kunz, W., Elger, C. E. and Helmstaedter, C. (2009). "Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat. " Epilepsia 50(6): 1432-1441.
    • (2009) Epilepsia , vol.50 , Issue.6 , pp. 1432-1441
    • Frisch, C.1    Husch, K.2    Angenstein, F.3    Kudin, A.4    Kunz, W.5    Elger, C.E.6    Helmstaedter, C.7
  • 26
    • 34247512211 scopus 로고    scopus 로고
    • Differential fear conditioning in asperger's syndrome: Implications for an amygdala theory of autism
    • Gaigg, S. B. and Bowler, D. M. (2007). "Differential fear conditioning in asperger's syndrome: Implications for an amygdala theory of autism. " Neuropsychologia 45(9): 2125-2134.
    • (2007) Neuropsychologia , vol.45 , Issue.9 , pp. 2125-2134
    • Gaigg, S.B.1    Bowler, D.M.2
  • 27
    • 78649838895 scopus 로고    scopus 로고
    • Validating gamma oscillations and delayed auditory responses as translational biomarkers of autism
    • Gandal, M. J., Edgar, J. C., Ehrlichman, R. S., Mehta, M., Roberts, T. P. and Siegel, S. J. (2010). "Validating gamma oscillations and delayed auditory responses as translational biomarkers of autism. " Biol Psychiatry 68(12): 1100-1106.
    • (2010) Biol Psychiatry , vol.68 , Issue.12 , pp. 1100-1106
    • Gandal, M.J.1    Edgar, J.C.2    Ehrlichman, R.S.3    Mehta, M.4    Roberts, T.P.5    Siegel, S.J.6
  • 28
    • 84865268274 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the gsk-3beta/beta-catenin pathway
    • Go, H. S., Kim, K. C., Choi, C. S., Jeon, S. J., Kwon, K. J., Han, S. H., Lee, J., Cheong, J. H., Ryu, J. H., Kim, C. H., Ko, K. H. and Shin, C. Y. (2012). "Prenatal exposure to valproic acid increases the neural progenitor cell pool and induces macrocephaly in rat brain via a mechanism involving the gsk-3beta/beta-catenin pathway. " Neuropharmacology 63(6): 1028-1041.
    • (2012) Neuropharmacology , vol.63 , Issue.6 , pp. 1028-1041
    • Go, H.S.1    Kim, K.C.2    Choi, C.S.3    Jeon, S.J.4    Kwon, K.J.5    Han, S.H.6    Lee, J.7    Cheong, J.H.8    Ryu, J.H.9    Kim, C.H.10    Ko, K.H.11    Shin, C.Y.12
  • 29
    • 77953545864 scopus 로고    scopus 로고
    • The role of mecp2 in brain development and neurodevelopmental disorders
    • Gonzales, M. L. and LaSalle, J. M. (2010). "The role of mecp2 in brain development and neurodevelopmental disorders. " Curr Psychiatry Rep 12(2): 127-134.
    • (2010) Curr Psychiatry Rep , vol.12 , Issue.2 , pp. 127-134
    • Gonzales, M.L.1    LaSalle, J.M.2
  • 31
    • 84867205632 scopus 로고    scopus 로고
    • Effect of prenatal valproic acid exposure on cortical morphology in female mice
    • Hara, Y., Maeda, Y., Kataoka, S., Ago, Y., Takuma, K. and Matsuda, T. (2012). "Effect of prenatal valproic acid exposure on cortical morphology in female mice. " J Pharmacol Sci 118(4): 543-546.
    • (2012) J Pharmacol Sci , vol.118 , Issue.4 , pp. 543-546
    • Hara, Y.1    Maeda, Y.2    Kataoka, S.3    Ago, Y.4    Takuma, K.5    Matsuda, T.6
  • 32
    • 0019293547 scopus 로고
    • Chromodacryorrhea in laboratory rats (rattus norvegicus): Etiologic considerations
    • Harkness, J. E. and Ridgway, M. D. (1980). "Chromodacryorrhea in laboratory rats (rattus norvegicus): Etiologic considerations. " Lab Anim Sci 30(5): 841-844.
    • (1980) Lab Anim Sci , vol.30 , Issue.5 , pp. 841-844
    • Harkness, J.E.1    Ridgway, M.D.2
  • 33
    • 0023697903 scopus 로고
    • Valproic acid developmental toxicity and pharmacokinetics in the rhesus monkey: An interspecies comparison
    • Hendrickx, A. G., Nau, H., Binkerd, P., Rowland, J. M., Rowland, J. R., Cukierski, M. J. and Cukierski, M. A. (1988). "Valproic acid developmental toxicity and pharmacokinetics in the rhesus monkey: An interspecies comparison. " Teratology 38(4): 329-345.
    • (1988) Teratology , vol.38 , Issue.4 , pp. 329-345
    • Hendrickx, A.G.1    Nau, H.2    Binkerd, P.3    Rowland, J.M.4    Rowland, J.R.5    Cukierski, M.J.6    Cukierski, M.A.7
  • 35
    • 0023389888 scopus 로고
    • Secretory response to light in rat harderian gland: Possible photoprotective role of harderian porphyrin
    • Hugo, J., Krijt, J., Vokurka, M. and Janousek, V. (1987). "Secretory response to light in rat harderian gland: Possible photoprotective role of harderian porphyrin. " Gen Physiol Biophys 6(4): 401-404.
    • (1987) Gen Physiol Biophys , vol.6 , Issue.4 , pp. 401-404
    • Hugo, J.1    Krijt, J.2    Vokurka, M.3    Janousek, V.4
  • 36
    • 0034612151 scopus 로고    scopus 로고
    • Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism
    • Ingram, J. L., Peckham, S. M., Tisdale, B. and Rodier, P. M. (2000). "Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism. " Neurotoxicology and Teratology 22: 319-324.
    • (2000) Neurotoxicology and Teratology , vol.22 , pp. 319-324
    • Ingram, J.L.1    Peckham, S.M.2    Tisdale, B.3    Rodier, P.M.4
  • 37
    • 84856328957 scopus 로고    scopus 로고
    • New frontiers in animal research of psychiatric illness
    • Kaffman, A. and Krystal, J. H. (2012). "New frontiers in animal research of psychiatric illness. " Methods Mol Biol 829: 3-30.
    • (2012) Methods Mol Biol , vol.829 , pp. 3-30
    • Kaffman, A.1    Krystal, J.H.2
  • 38
    • 84868616944 scopus 로고    scopus 로고
    • A review of the evidence for the canonical wnt pathway in autism spectrum disorders
    • Kalkman, H. O. (2012). "A review of the evidence for the canonical wnt pathway in autism spectrum disorders. " Mol Autism 3(1): 10.
    • (2012) Mol Autism , vol.3 , Issue.1 , pp. 10
    • Kalkman, H.O.1
  • 39
    • 0000984981 scopus 로고
    • Autistic disturbances of affective contact
    • Kanner, L. (1943). "Autistic disturbances of affective contact. " Nervous Child 2: 217-250.
    • (1943) Nervous Child , vol.2 , pp. 217-250
    • Kanner, L.1
  • 40
    • 84865185136 scopus 로고    scopus 로고
    • Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid
    • Kataoka, S., Takuma, K., Hara, Y., Maeda, Y., Ago, Y. and Matsuda, T. (2011). "Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid. " Int J Neuropsychopharmacol: 1-13.
    • (2011) Int J Neuropsychopharmacol , pp. 1-13
    • Kataoka, S.1    Takuma, K.2    Hara, Y.3    Maeda, Y.4    Ago, Y.5    Matsuda, T.6
  • 42
    • 0038635882 scopus 로고    scopus 로고
    • Meal pattern changes associated with temporomandibular joint inflammation/pain in rats; analgesic effects
    • Kerins, C. A., Carlson, D. S., McIntosh, J. E. and Bellinger, L. L. (2003). "Meal pattern changes associated with temporomandibular joint inflammation/pain in rats; analgesic effects. " Pharmacol Biochem Behav 75(1): 181-189.
    • (2003) Pharmacol Biochem Behav , vol.75 , Issue.1 , pp. 181-189
    • Kerins, C.A.1    Carlson, D.S.2    McIntosh, J.E.3    Bellinger, L.L.4
  • 43
    • 84874702940 scopus 로고    scopus 로고
    • Male-specific alteration in excitatory post-synaptic development and social interaction in pre-natal valproic acid exposure model of autism spectrum disorder
    • Kim, K. C., Kim, P., Go, H. S., Choi, C. S., Park, J. H., Kim, H. J., Jeon, S. J., Dela Pena, I. C., Han, S. H., Cheong, J. H., Ryu, J. H. and Shin, C. Y. (2013). "Male-specific alteration in excitatory post-synaptic development and social interaction in pre-natal valproic acid exposure model of autism spectrum disorder. " J Neurochem 124(6): 832-843.
    • (2013) J Neurochem , vol.124 , Issue.6 , pp. 832-843
    • Kim, K.C.1    Kim, P.2    Go, H.S.3    Choi, C.S.4    Park, J.H.5    Kim, H.J.6    Jeon, S.J.7    dela Pena, I.C.8    Han, S.H.9    Cheong, J.H.10    Ryu, J.H.11    Shin, C.Y.12
  • 44
    • 79651474341 scopus 로고    scopus 로고
    • The critical period of valproate exposure to induce autistic symptoms in sprague-dawley rats
    • Kim, K. C., Kim, P., Go, H. S., Choi, C. S., Yang, S. I., Cheong, J. H., Shin, C. Y. and Ko, K. H. (2011). "The critical period of valproate exposure to induce autistic symptoms in sprague-dawley rats. " Toxicol Lett 201(2): 137-142.
    • (2011) Toxicol Lett , vol.201 , Issue.2 , pp. 137-142
    • Kim, K.C.1    Kim, P.2    Go, H.S.3    Choi, C.S.4    Yang, S.I.5    Cheong, J.H.6    Shin, C.Y.7    Ko, K.H.8
  • 45
    • 33845735209 scopus 로고    scopus 로고
    • Fetal valproate syndrome: A review
    • Kini, U. (2006). "Fetal valproate syndrome: A review. " Paediatric and Perinatal Drug Therapy 7(3): 123-130.
    • (2006) Paediatric and Perinatal Drug Therapy , vol.7 , Issue.3 , pp. 123-130
    • Kini, U.1
  • 46
    • 76249121818 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice
    • Kolozsi, E., Mackenzie, R. N., Roullet, F. I., deCatanzaro, D. and Foster, J. A. (2009). "Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice. " Neuroscience 163(4): 1201-1210.
    • (2009) Neuroscience , vol.163 , Issue.4 , pp. 1201-1210
    • Kolozsi, E.1    McKenzie, R.N.2    Roullet, F.I.3    deCatanzaro, D.4    Foster, J.A.5
  • 47
    • 0035863662 scopus 로고    scopus 로고
    • Valproic acid embryopathy: Report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature
    • Kozma, C. (2001). "Valproic acid embryopathy: Report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature. " Am J Med Genet 98(2): 168-175.
    • (2001) Am J Med Genet , vol.98 , Issue.2 , pp. 168-175
    • Kozma, C.1
  • 49
    • 84863007530 scopus 로고    scopus 로고
    • Reelin and its complex involvement in brain development and function
    • Lakatosova, S. and Ostatnikova, D. (2012). "Reelin and its complex involvement in brain development and function. " Int J Biochem Cell Biol 44(9): 1501-1504.
    • (2012) Int J Biochem Cell Biol , vol.44 , Issue.9 , pp. 1501-1504
    • Lakatosova, S.1    Ostatnikova, D.2
  • 50
    • 0037742375 scopus 로고    scopus 로고
    • Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action
    • Loscher, W. (1999). "Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action. " Prog Neurobiol 58(1): 31-59.
    • (1999) Prog Neurobiol , vol.58 , Issue.1 , pp. 31-59
    • Loscher, W.1
  • 51
    • 0036402177 scopus 로고    scopus 로고
    • Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy
    • Loscher, W. (2002). "Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy. " CNS Drugs 16(10): 669-694.
    • (2002) CNS Drugs , vol.16 , Issue.10 , pp. 669-694
    • Loscher, W.1
  • 52
    • 56449091791 scopus 로고    scopus 로고
    • Anxiety in children and adolescents with autism spectrum disorders
    • MacNeil, B. M., Lopes, V. A. and Minnes, P. M. (2009). "Anxiety in children and adolescents with autism spectrum disorders. " Research in Autism Spectrum Disorders 3(1): 1-21.
    • (2009) Research in Autism Spectrum Disorders , vol.3 , Issue.1 , pp. 1-21
    • McNeil, B.M.1    Lopes, V.A.2    Minnes, P.M.3
  • 53
    • 67149107463 scopus 로고    scopus 로고
    • The intense world syndrome-an alternative hypothesis for autism
    • Markram, H., Rinaldi, T. and Markram, K. (2007). "The intense world syndrome-an alternative hypothesis for autism. " Front Neurosci 1(1): 77-96.
    • (2007) Front Neurosci , vol.1 , Issue.1 , pp. 77-96
    • Markram, H.1    Rinaldi, T.2    Markram, K.3
  • 54
    • 79953020632 scopus 로고    scopus 로고
    • The intense world theory-a unifying theory of the neurobiology of autism
    • Markram, K. and Markram, H. (2010). "The intense world theory-a unifying theory of the neurobiology of autism. " Front Hum Neurosci 4: 224.
    • (2010) Front Hum Neurosci , vol.4 , pp. 224
    • Markram, K.1    Markram, H.2
  • 55
    • 39149089652 scopus 로고    scopus 로고
    • Abnormal fear conditioning and amygdala processing in an animal model of autism
    • Markram, K., Rinaldi, T., La Mendola, D., Sandi, C. and Markram, H. (2008). "Abnormal fear conditioning and amygdala processing in an animal model of autism. " Neuropsychopharmacology 33(4): 901-912.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.4 , pp. 901-912
    • Markram, K.1    Rinaldi, T.2    la Mendola, D.3    Sandi, C.4    Markram, H.5
  • 58
    • 80053929841 scopus 로고    scopus 로고
    • Mglur5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the vpa model of autism
    • Mehta, M. V., Gandal, M. J. and Siegel, S. J. (2011). "Mglur5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the vpa model of autism. " PLoS One 6(10): e26077.
    • (2011) PLoS One , vol.6 , Issue.10
    • Mehta, M.V.1    Gandal, M.J.2    Siegel, S.J.3
  • 59
    • 0034709291 scopus 로고    scopus 로고
    • Value of a clinical morphology examination in autism
    • Miles, J. H. and Hillman, R. E. (2000). "Value of a clinical morphology examination in autism. " Am J Med Genet 91(4): 245-253.
    • (2000) Am J Med Genet , vol.91 , Issue.4 , pp. 245-253
    • Miles, J.H.1    Hillman, R.E.2
  • 60
    • 84858674139 scopus 로고    scopus 로고
    • The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies
    • Modi, M. E. and Young, L. J. (2012). "The oxytocin system in drug discovery for autism: Animal models and novel therapeutic strategies. " Horm Behav 61(3): 340-350.
    • (2012) Horm Behav , vol.61 , Issue.3 , pp. 340-350
    • Modi, M.E.1    Young, L.J.2
  • 62
    • 70349591892 scopus 로고    scopus 로고
    • D-aspartate affects secretory activity in rat harderian gland: Molecular mechanism and functional significance
    • Monteforte, R., Santillo, A., Di Giovanni, M., D'Aniello, A., Di Maro, A. and Chieffi Baccari, G. (2009). "D-aspartate affects secretory activity in rat harderian gland: Molecular mechanism and functional significance. " Amino acids 37(4): 653-664.
    • (2009) Amino acids , vol.37 , Issue.4 , pp. 653-664
    • Monteforte, R.1    Santillo, A.2    Di Giovanni, M.3    D'Aniello, A.4    Di Maro, A.5    Chieffi Baccari, G.6
  • 64
    • 0031829430 scopus 로고    scopus 로고
    • Comorbid anxiety symptoms in children with pervasive developmental disorders
    • Muris, P., Steerneman, P., Merckelbach, H., Holdrinet, I. and Meesters, C. (1998). "Comorbid anxiety symptoms in children with pervasive developmental disorders. " J Anxiety Disord 12(4): 387-393.
    • (1998) J Anxiety Disord , vol.12 , Issue.4 , pp. 387-393
    • Muris, P.1    Steerneman, P.2    Merckelbach, H.3    Holdrinet, I.4    Meesters, C.5
  • 65
    • 84864824600 scopus 로고    scopus 로고
    • Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy
    • Mychasiuk, R., Richards, S., Nakahashi, A., Kolb, B. and Gibb, R. (2012). "Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy. " Dev Neurosci 34(2-3): 268-276.
    • (2012) Dev Neurosci , vol.34 , Issue.2-3 , pp. 268-276
    • Mychasiuk, R.1    Richards, S.2    Nakahashi, A.3    Kolb, B.4    Gibb, R.5
  • 66
    • 0026689132 scopus 로고
    • Autism in fetal alcohol syndrome: A report of six cases
    • Nanson, J. L. (1992). "Autism in fetal alcohol syndrome: A report of six cases. " Alcohol Clin Exp Res 16(3): 558-565.
    • (1992) Alcohol Clin Exp Res , vol.16 , Issue.3 , pp. 558-565
    • Nanson, J.L.1
  • 67
    • 73249133910 scopus 로고    scopus 로고
    • Nonexploratory movement and behavioral alterations in a thalidomide or valproic acid-induced autism model rat
    • Narita, M., Oyabu, A., Imura, Y., Kamada, N., Yokoyama, T., Tano, K., Uchida, A. and Narita, N. (2010). "Nonexploratory movement and behavioral alterations in a thalidomide or valproic acid-induced autism model rat. " Neurosci Res 66(1): 2-6.
    • (2010) Neurosci Res , vol.66 , Issue.1 , pp. 2-6
    • Narita, M.1    Oyabu, A.2    Imura, Y.3    Kamada, N.4    Yokoyama, T.5    Tano, K.6    Uchida, A.7    Narita, N.8
  • 68
    • 0020401577 scopus 로고
    • Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics
    • Nau, H., Kuhnz, W., Egger, H. J., Rating, D. and Helge, H. (1982). "Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics. " Clin Pharmacokinet 7(6): 508-543.
    • (1982) Clin Pharmacokinet , vol.7 , Issue.6 , pp. 508-543
    • Nau, H.1    Kuhnz, W.2    Egger, H.J.3    Rating, D.4    Helge, H.5
  • 69
    • 67349218856 scopus 로고    scopus 로고
    • Valproic acid in pregnancy: How much are we endangering the embryo and fetus?
    • Ornoy, A. (2009). "Valproic acid in pregnancy: How much are we endangering the embryo and fetus?" Reprod Toxicol 28(1): 1-10.
    • (2009) Reprod Toxicol , vol.28 , Issue.1 , pp. 1-10
    • Ornoy, A.1
  • 70
    • 33846578187 scopus 로고    scopus 로고
    • Sensorimotor gating deficits in adults with autism
    • Perry, W., Minassian, A., Lopez, B., Maron, L. and Lincoln, A. (2007). "Sensorimotor gating deficits in adults with autism. " Biol Psychiatry 61(4): 482-486.
    • (2007) Biol Psychiatry , vol.61 , Issue.4 , pp. 482-486
    • Perry, W.1    Minassian, A.2    Lopez, B.3    Maron, L.4    Lincoln, A.5
  • 72
    • 34548085412 scopus 로고    scopus 로고
    • Elevated nmda receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid
    • Rinaldi, T., Kulangara, K., Antoniello, K. and Markram, H. (2007). "Elevated nmda receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid. " Proceedings of the National Academy of Sciences 104(33): 13501-13506.
    • (2007) Proceedings of the National Academy of Sciences , vol.104 , Issue.33 , pp. 13501-13506
    • Rinaldi, T.1    Kulangara, K.2    Antoniello, K.3    Markram, H.4
  • 73
    • 70349461649 scopus 로고    scopus 로고
    • Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic acid animal model of autism
    • Rinaldi, T., Perrodin, C. and Markram, H. (2008a). "Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic acid animal model of autism. " Frontiers in Neural Circuits 2.
    • (2008) Frontiers in Neural Circuits , pp. 2
    • Rinaldi, T.1    Perrodin, C.2    Markram, H.3
  • 74
    • 40849139253 scopus 로고    scopus 로고
    • Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid
    • Rinaldi, T., Silberberg, G. and Markram, H. (2008b). "Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid. " Cereb Cortex 18(4): 763-770.
    • (2008) Cereb Cortex , vol.18 , Issue.4 , pp. 763-770
    • Rinaldi, T.1    Silberberg, G.2    Markram, H.3
  • 75
    • 0036616665 scopus 로고    scopus 로고
    • Converging evidence for brain stem injury in autism
    • Rodier, P. M. (2002). "Converging evidence for brain stem injury in autism. " Dev Psychopathol 14(3): 537-557.
    • (2002) Dev Psychopathol , vol.14 , Issue.3 , pp. 537-557
    • Rodier, P.M.1
  • 76
    • 1042301324 scopus 로고    scopus 로고
    • 2003 warkany lecture: Autism as a birth defect
    • Rodier, P. M. (2004). "2003 warkany lecture: Autism as a birth defect. " Birth Defects Res A Clin Mol Teratol 70(1): 1-6.
    • (2004) Birth Defects Res A Clin Mol Teratol , vol.70 , Issue.1 , pp. 1-6
    • Rodier, P.M.1
  • 77
    • 0031104734 scopus 로고    scopus 로고
    • Linking etiologies in humans and animal models: Studies of autism
    • Rodier, P. M., Ingram, J. L., Tisdale, B. and Croog, V. J. (1997). "Linking etiologies in humans and animal models: Studies of autism. " Reprod Toxicol 11(2-3): 417-422.
    • (1997) Reprod Toxicol , vol.11 , Issue.2-3 , pp. 417-422
    • Rodier, P.M.1    Ingram, J.L.2    Tisdale, B.3    Croog, V.J.4
  • 78
    • 0029990539 scopus 로고    scopus 로고
    • Embryological origin for autism: Developmental anomalies of the cranial nerve motor nuclei
    • Rodier, P. M., Ingram, J. L., Tisdale, B., Nelson, S. and Romano, J. (1996). "Embryological origin for autism: Developmental anomalies of the cranial nerve motor nuclei. " J Comp Neurol 370(2): 247-261.
    • (1996) J Comp Neurol , vol.370 , Issue.2 , pp. 247-261
    • Rodier, P.M.1    Ingram, J.L.2    Tisdale, B.3    Nelson, S.4    Romano, J.5
  • 79
    • 81955161403 scopus 로고    scopus 로고
    • Mouse models of autism: Testing hypotheses about molecular mechanisms
    • Roullet, F. I. and Crawley, J. N. (2011). "Mouse models of autism: Testing hypotheses about molecular mechanisms. " Curr Top Behav Neurosci 7: 187-212.
    • (2011) Curr Top Behav Neurosci , vol.7 , pp. 187-212
    • Roullet, F.I.1    Crawley, J.N.2
  • 80
    • 84875666213 scopus 로고    scopus 로고
    • In utero exposure to valproic acid and autism--a current review of clinical and animal studies
    • Roullet, F. I., Lai, J. K. and Foster, J. A. (2013). "In utero exposure to valproic acid and autism--a current review of clinical and animal studies. " Neurotoxicol Teratol 36: 47-56.
    • (2013) Neurotoxicol Teratol , vol.36 , pp. 47-56
    • Roullet, F.I.1    Lai, J.K.2    Foster, J.A.3
  • 81
    • 77956184210 scopus 로고    scopus 로고
    • Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid
    • Roullet, F. I., Wollaston, L., Decatanzaro, D. and Foster, J. A. (2010). "Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid. " Neuroscience 170(2): 514-522.
    • (2010) Neuroscience , vol.170 , Issue.2 , pp. 514-522
    • Roullet, F.I.1    Wollaston, L.2    Decatanzaro, D.3    Foster, J.A.4
  • 82
    • 70349564808 scopus 로고    scopus 로고
    • The co-occurrence of autism and birth defects: Prevalence and risk in a population-based cohort
    • Schendel, D. E., Autry, A., Wines, R. and Moore, C. (2009). "The co-occurrence of autism and birth defects: Prevalence and risk in a population-based cohort. " Dev Med Child Neurol 51(10): 779-786.
    • (2009) Dev Med Child Neurol , vol.51 , Issue.10 , pp. 779-786
    • Schendel, D.E.1    Autry, A.2    Wines, R.3    Moore, C.4
  • 83
    • 0035215022 scopus 로고    scopus 로고
    • Nociceptive changes in rats after prenatal exposure to valproic acid
    • Schneider, T., Labuz, D. and Przewlocki, R. (2001). "Nociceptive changes in rats after prenatal exposure to valproic acid. " Pol J Pharmacol 53(5): 531-534.
    • (2001) Pol J Pharmacol , vol.53 , Issue.5 , pp. 531-534
    • Schneider, T.1    Labuz, D.2    Przewlocki, R.3
  • 84
    • 11144259318 scopus 로고    scopus 로고
    • Behavioral alterations in rats prenatally exposed to valproic acid: Animal model of autism
    • Schneider, T. and Przewlocki, R. (2005). "Behavioral alterations in rats prenatally exposed to valproic acid: Animal model of autism. " Neuropsychopharmacology 30(1): 80-89.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.1 , pp. 80-89
    • Schneider, T.1    Przewlocki, R.2
  • 85
    • 32844457426 scopus 로고    scopus 로고
    • Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: Issues for a therapeutic approach in autism
    • Schneider, T., Turczak, J. and Przewlocki, R. (2006). "Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: Issues for a therapeutic approach in autism. " Neuropsychopharmacology 31(1): 36-46.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.1 , pp. 36-46
    • Schneider, T.1    Turczak, J.2    Przewlocki, R.3
  • 86
    • 34447626496 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism
    • Schneider, T., Ziolkowska, B., Gieryk, A., Tyminska, A. and Przewlocki, R. (2007). "Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism. " Psychopharmacology (Berl) 193(4): 547-555.
    • (2007) Psychopharmacology (Berl) , vol.193 , Issue.4 , pp. 547-555
    • Schneider, T.1    Ziolkowska, B.2    Gieryk, A.3    Tyminska, A.4    Przewlocki, R.5
  • 87
    • 84858251298 scopus 로고    scopus 로고
    • Characteristics and anxiety symptom presentation associated with autism spectrum traits in youth with anxiety disorders
    • Settipani, C. A., Puleo, C. M., Conner, B. T. and Kendall, P. C. (2012). "Characteristics and anxiety symptom presentation associated with autism spectrum traits in youth with anxiety disorders. " J Anxiety Disord 26(3): 459-467.
    • (2012) J Anxiety Disord , vol.26 , Issue.3 , pp. 459-467
    • Settipani, C.A.1    Puleo, C.M.2    Conner, B.T.3    Kendall, P.C.4
  • 89
    • 33845284211 scopus 로고    scopus 로고
    • Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism
    • Stanton, M. E., Peloso, E., Brown, K. L. and Rodier, P. (2007). "Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism. " Behav Brain Res 176(1): 133-140.
    • (2007) Behav Brain Res , vol.176 , Issue.1 , pp. 133-140
    • Stanton, M.E.1    Peloso, E.2    Brown, K.L.3    Rodier, P.4
  • 91
    • 84862810515 scopus 로고    scopus 로고
    • Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories
    • Sui, L. and Chen, M. (2012). "Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories. " Brain Res Bull 87(6): 556-563.
    • (2012) Brain Res Bull , vol.87 , Issue.6 , pp. 556-563
    • Sui, L.1    Chen, M.2
  • 92
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • Sullivan, P. F., Daly, M. J. and O'Donovan, M. (2012). "Genetic architectures of psychiatric disorders: The emerging picture and its implications. " Nat Rev Genet 13(8): 537-551.
    • (2012) Nat Rev Genet , vol.13 , Issue.8 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 93
    • 79955758367 scopus 로고    scopus 로고
    • Morphological abnormalities of embryonic cranial nerves after in utero exposure to valproic acid: Implications for the pathogenesis of autism with multiple developmental anomalies
    • Tashiro, Y., Oyabu, A., Imura, Y., Uchida, A., Narita, N. and Narita, M. (2011). "Morphological abnormalities of embryonic cranial nerves after in utero exposure to valproic acid: Implications for the pathogenesis of autism with multiple developmental anomalies. " Int J Dev Neurosci 29(4): 359-364.
    • (2011) Int J Dev Neurosci , vol.29 , Issue.4 , pp. 359-364
    • Tashiro, Y.1    Oyabu, A.2    Imura, Y.3    Uchida, A.4    Narita, N.5    Narita, M.6
  • 94
    • 80052044947 scopus 로고    scopus 로고
    • Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis
    • van Steensel, F. J., Bogels, S. M. and Perrin, S. (2011). "Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. " Clin Child Fam Psychol Rev 14(3): 302-317.
    • (2011) Clin Child Fam Psychol Rev , vol.14 , Issue.3 , pp. 302-317
    • van Steensel, F.J.1    Bogels, S.M.2    Perrin, S.3
  • 95
    • 0023257580 scopus 로고
    • Behavioral teratogenicity of valproic acid: Selective effects on behavior after prenatal exposure to rats
    • Vorhees, C. V. (1987). "Behavioral teratogenicity of valproic acid: Selective effects on behavior after prenatal exposure to rats. " Psychopharmacology (Berl) 92(2): 173-179.
    • (1987) Psychopharmacology (Berl) , vol.92 , Issue.2 , pp. 173-179
    • Vorhees, C.V.1
  • 96
    • 33747850275 scopus 로고    scopus 로고
    • A new neurobehavioral model of autism in mice: Pre-and postnatal exposure to sodium valproate
    • Wagner, G. C., Reuhl, K. R., Cheh, M., McRae, P. and Halladay, A. K. (2006). "A new neurobehavioral model of autism in mice: Pre-and postnatal exposure to sodium valproate. " J Autism Dev Disord 36(6): 779-793.
    • (2006) J Autism Dev Disord , vol.36 , Issue.6 , pp. 779-793
    • Wagner, G.C.1    Reuhl, K.R.2    Cheh, M.3    McRae, P.4    Halladay, A.K.5
  • 97
    • 80455177363 scopus 로고    scopus 로고
    • The prevalence puzzle: Autism counts
    • Weintraub, K. (2011). "The prevalence puzzle: Autism counts. " Nature 479(7371): 22-24.
    • (2011) Nature , vol.479 , Issue.7371 , pp. 22-24
    • Weintraub, K.1
  • 98
    • 80051648792 scopus 로고    scopus 로고
    • Above genetics: Lessons from cerebral development in autism
    • Williams, E. L. and Casanova, M. F. (2011). "Above genetics: Lessons from cerebral development in autism. " Transl Neurosci 2(2): 106-120.
    • (2011) Transl Neurosci , vol.2 , Issue.2 , pp. 106-120
    • Williams, E.L.1    Casanova, M.F.2
  • 99
    • 84879714373 scopus 로고    scopus 로고
    • A review on the current neuroligin mouse models
    • Xu, J. Y., Xia, Q. Q. and Xia, J. (2012). "A review on the current neuroligin mouse models. " Sheng Li Xue Bao 64(5): 550-562.
    • (2012) Sheng Li Xue Bao , vol.64 , Issue.5 , pp. 550-562
    • Xu, J.Y.1    Xia, Q.Q.2    Xia, J.3
  • 100
    • 79954590474 scopus 로고    scopus 로고
    • Epigenetic impacts on neurodevelopment: Pathophysiological mechanisms and genetic modes of action
    • Zahir, F. R. and Brown, C. J. (2011). "Epigenetic impacts on neurodevelopment: Pathophysiological mechanisms and genetic modes of action. " Pediatr Res 69(5 Pt 2): 92R-100R.
    • (2011) Pediatr Res , vol.69 , Issue.5 PART 2
    • Zahir, F.R.1    Brown, C.J.2
  • 101
    • 84862866769 scopus 로고    scopus 로고
    • Downregulating the canonical wnt/beta-catenin signaling pathway attenuates the susceptibility to autism-like phenotypes by decreasing oxidative stress
    • Zhang, Y., Sun, Y., Wang, F., Wang, Z., Peng, Y. and Li, R. (2012). "Downregulating the canonical wnt/beta-catenin signaling pathway attenuates the susceptibility to autism-like phenotypes by decreasing oxidative stress. " Neurochem Res 37(7): 1409-1419.
    • (2012) Neurochem Res , vol.37 , Issue.7 , pp. 1409-1419
    • Zhang, Y.1    Sun, Y.2    Wang, F.3    Wang, Z.4    Peng, Y.5    Li, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.