Development of BODIPY FL Vindoline as a Novel and High-Affinity Pregnane X Receptor Fluorescent Probe

Bioconjugate Chemistry

Volumn 25, Issue 9, 2014, Pages 1664-1677

  Lin, Wenwei ^a   Liu, Jiuyu ^a   Jeffries, Cynthia ^a   Yang, Lei ^a   Lu, Yan ^a   Lee, Richard E ^a   Chen, Taosheng ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; BINDING ENERGY; DRUG INTERACTIONS; ENERGY TRANSFER; FORSTER RESONANCE ENERGY TRANSFER; LIGANDS; PROBES;

DRUG LEADS; DRUG-DRUG INTERACTIONS; DRUG-METABOLIZING ENZYMES; FLUORESCENCE RESONANCE ENERGY TRANSFER ASSAYS; FLUORESCENT PROBES; HIGH AFFINITY; NONRADIOACTIVE; TIME-RESOLVED FLUORESCENCE; VINBLASTINE; VINDOLINE;

FLUORESCENCE SPECTROSCOPY;

BODIPY FL CATHARANTHINE; BODIPY FL VINBLASTINE; BODIPY FL VINDOLINE; CATHARANTHINE; CATHARANTHINIC ACID; CLOTRIMAZOLE; DEACETYLVINBLASTINE; DEACETYLVINDOLINE; FLUORESCENT DYE; GINKGOLIDE A; GINKGOLIDE B; HYPERFORIN; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; PREGNANE X RECEPTOR; PROPIONIC ACID; PROTEIN INHIBITOR; RIFAMPICIN; SR 12813; SULFO CY5 VINDOLINE; UNCLASSIFIED DRUG; VINBLASTINE; VINDOLINE; 4,4-DIFLUORO-4-BORA-3A,4A-DIAZA-S-INDACENE; BORON DERIVATIVE; DIMETHYL SULFOXIDE; STEROID RECEPTOR;

ARTICLE; BINDING ASSAY; CHEMICAL STRUCTURE; ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; LIGAND BINDING; MITSUNOBU REACTION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; STEREOSPECIFICITY; SYNTHESIS; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG DESIGN; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE;

BORON COMPOUNDS; DIMETHYL SULFOXIDE; DRUG DESIGN; FLUORESCENT DYES; HUMANS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, STEROID; VINBLASTINE;

EID: 84927517499     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc5002856     Document Type: Article

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