The genetic architecture of methotrexate toxicity is similar in drosophila melanogaster and humans

G3: Genes, Genomes, Genetics

Volumn 3, Issue 8, 2013, Pages 1301-1310

  Kislukhin, Galina ^a   King, Elizabeth G ^a   Walters, Kelli N ^a   Macdonald, Stuart J ^b   Long, Anthony D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF KANSAS   (United States)

Author keywords

Chemotoxicity; Drosophila; Methotrexate; Pharmacogenomics; Population; Quantitative; Resource; Synthetic; Trait loci

Indexed keywords

AMINO ACID; DROSOPHILA PROTEIN; GLUTATHIONE PEROXIDASE; METHOTREXATE;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MODEL; CENTROMERE; CHEMOTOXICITY; CHROMOSOME MAP; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DROSOPHILA SYNTHETIC POPULATION RESOURCE; DRUG EFFECT; EXON; FEMALE; FERTILITY; GENETICS; GENOTOXICITY; HUMAN; NONHUMAN; PHARMACOGENOMICS; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; RECOMBINANT INBRED STRAIN; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSPOSON;

DROSOPHILA MELANOGASTER;

CHEMOTOXICITY; DROSOPHILA SYNTHETIC POPULATION RESOURCE; METHOTREXATE; PHARMACOGENOMICS; QUANTITATIVE TRAIT LOCI;

ANIMALS; CENTROMERE; CHROMOSOME MAPPING; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; FERTILITY; GLUTATHIONE PEROXIDASE; HUMANS; METHOTREXATE; MODELS, GENETIC; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 84883614860     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.006619     Document Type: Article

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