메뉴 건너뛰기




Volumn 11, Issue 101, 2014, Pages

Cell morphology and focal adhesion location alters internal cell stress

Author keywords

Extracellular mechanical environment; Finite element; Focal adhesion; Osteoblast; Osteocyte; Single cell force microscopy

Indexed keywords

ADHESION; ATOMIC FORCE MICROSCOPY; CYTOLOGY; ENZYME ACTIVITY; FINITE ELEMENT METHOD; MOBILE SECURITY; MORPHOLOGY; OSTEOBLASTS; STIFFNESS; STRESSES; SUBSTRATES;

EID: 84927142616     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2014.0885     Document Type: Article
Times cited : (46)

References (89)
  • 1
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • Pelham RJ, Wang Y-L. 1997 Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl Acad. Sci. USA 94, 13 661-13 665. (doi:10.1073/pnas.94.25.13661)
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13661-13665
    • Pelham, R.J.1    Wang, Y.-L.2
  • 2
    • 34347204139 scopus 로고    scopus 로고
    • Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates
    • Saez A, Ghibaudo M, Buguin A, Silberzan P, Ladoux B. 2007 Rigidity-driven growth and migration of epithelial cells on microstructured anisotropic substrates. Proc. Natl Acad. Sci. USA 104, 8281-8286. (doi:10.1073/pnas.0702259104)
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8281-8286
    • Saez, A.1    Ghibaudo, M.2    Buguin, A.3    Silberzan, P.4    Ladoux, B.5
  • 3
    • 84868207601 scopus 로고    scopus 로고
    • The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy
    • Bian L, Hou C, Tous E, Rai R, Mauck RL, Burdick JA. 2013 The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials 34, 413-421. (doi:10.1016/j.biomaterials.2012.09.052)
    • (2013) Biomaterials , vol.34 , pp. 413-421
    • Bian, L.1    Hou, C.2    Tous, E.3    Rai, R.4    Mauck, R.L.5    Burdick, J.A.6
  • 4
    • 0037345529 scopus 로고    scopus 로고
    • Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways
    • Kapur S, Baylink DJ, Lau WKH. 2003 Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. Bone 32, 241-251. (doi:10.1016/S8756- 3282(02)00979-1)
    • (2003) Bone , vol.32 , pp. 241-251
    • Kapur, S.1    Baylink, D.J.2    Lau, W.K.H.3
  • 6
    • 0031671026 scopus 로고    scopus 로고
    • Forces on adhesive contacts affect cell function
    • Galbraith CG, Sheetz MP. 1998 Forces on adhesive contacts affect cell function. Curr. Opin. Cell Biol. 10, 566-571. (doi:10.1016/S0955-0674(98)80030-6)
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 566-571
    • Galbraith, C.G.1    Sheetz, M.P.2
  • 7
    • 33744826245 scopus 로고    scopus 로고
    • Intrinsic mechanical properties of the extracellular matrix affect the behavior of pre-osteoblastic MC3T3-E1 cells
    • Khatiwala CB, Peyton SR, Putnam AJ. 2006 Intrinsic mechanical properties of the extracellular matrix affect the behavior of pre-osteoblastic MC3T3-E1 cells. Am. J. Physiol. Cell Physiol. 290, C1640-C1650. (doi:10.1152/ajpcell.00455.2005)
    • (2006) Am. J. Physiol. Cell Physiol. , vol.290 , pp. C1640-C1650
    • Khatiwala, C.B.1    Peyton, S.R.2    Putnam, A.J.3
  • 8
    • 77950649084 scopus 로고    scopus 로고
    • Dynamics of the transition from osteoblast to osteocyte
    • Dallas SL, Bonewald LF. 2010 Dynamics of the transition from osteoblast to osteocyte. Ann. NY Acad. Sci. 1192, 437-443. (doi:10.1111/j.1749-6632.2009.05246.x)
    • (2010) Ann. NY Acad. Sci. , vol.1192 , pp. 437-443
    • Dallas, S.L.1    Bonewald, L.F.2
  • 9
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • Engler AJ, Sen S, Sweeney HL, Discher DE. 2006 Matrix elasticity directs stem cell lineage specification. Cell 126, 677-689. (doi:10.1016/j.cell.2006.06.044)
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 11
    • 84883206752 scopus 로고    scopus 로고
    • Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation
    • Mullen CA, Haugh MG, Schaffler MB, Majeska RJ, McNamara LM. 2013 Osteocyte differentiation is regulated by extracellular matrix stiffness and intercellular separation. J. Mech. Behav. Biomed. Mater. 28, 183-194. (doi:10.1016/j.jmbbm.2013.06.013)
    • (2013) J. Mech. Behav. Biomed. Mater. , vol.28 , pp. 183-194
    • Mullen, C.A.1    Haugh, M.G.2    Schaffler, M.B.3    Majeska, R.J.4    McNamara, L.M.5
  • 12
    • 1842426730 scopus 로고    scopus 로고
    • Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
    • McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. 2004 Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell 6, 483-495. (doi:10.1016/S1534-5807(04)00075-9)
    • (2004) Dev. Cell , vol.6 , pp. 483-495
    • McBeath, R.1    Pirone, D.M.2    Nelson, C.M.3    Bhadriraju, K.4    Chen, C.S.5
  • 14
    • 84867030972 scopus 로고    scopus 로고
    • Influence of cell spreading and contractility on stiffness measurements using AFM
    • Vichare S, Inamdar MM, Sen S. 2012 Influence of cell spreading and contractility on stiffness measurements using AFM. Soft Matter 8, 10 464-10 471. (doi:10.1039/C2SM26348C)
    • (2012) Soft Matter , vol.8 , pp. 10464-10471
    • Vichare, S.1    Inamdar, M.M.2    Sen, S.3
  • 15
    • 37349005914 scopus 로고    scopus 로고
    • Fibroblast adaptation and stiffness matching to soft elastic substrates
    • Solon J, Levental I, Sengupta K, Georges PC, Janmey PA. 2007 Fibroblast adaptation and stiffness matching to soft elastic substrates. Biophys J. 93, 4453-4461. (doi:10.1529/biophysj.106.101386)
    • (2007) Biophys J. , vol.93 , pp. 4453-4461
    • Solon, J.1    Levental, I.2    Sengupta, K.3    Georges, P.C.4    Janmey, P.A.5
  • 17
    • 1442335302 scopus 로고    scopus 로고
    • Kinetic study on the elastic change of vascular endothelial cells on collagen matrices by atomic force microscopy
    • Sato H, Kataoka N, Kajiya F, Katano M, Takigawa T, Masuda T. 2004 Kinetic study on the elastic change of vascular endothelial cells on collagen matrices by atomic force microscopy. Colloids Surf. B Biointerfaces 34, 141-146. (doi:10.1016/j.colsurfb.2003.12.013)
    • (2004) Colloids Surf. B Biointerfaces , vol.34 , pp. 141-146
    • Sato, H.1    Kataoka, N.2    Kajiya, F.3    Katano, M.4    Takigawa, T.5    Masuda, T.6
  • 18
    • 27744526762 scopus 로고    scopus 로고
    • Indentation and adhesive probing of a cell membrane with AFM: Theoretical model and experiments
    • Sen S, Subramanian S, Discher DE. 2005 Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments. Biophys. J. 89, 3203-3213. (doi:10.1529/biophysj.105.063826)
    • (2005) Biophys. J. , vol.89 , pp. 3203-3213
    • Sen, S.1    Subramanian, S.2    Discher, D.E.3
  • 19
    • 84901613331 scopus 로고    scopus 로고
    • Mechanical stiffness as an improved single-cell indicator of osteoblastic human mesenchymal stem cell differentiation
    • Bongiorno T et al. 2013 Mechanical stiffness as an improved single-cell indicator of osteoblastic human mesenchymal stem cell differentiation. J. Biomech. 47, 2197-2204. (doi:10.1016/j.jbiomech.2013.11.017)
    • (2013) J. Biomech. , vol.47 , pp. 2197-2204
    • Bongiorno, T.1
  • 20
    • 0031969588 scopus 로고    scopus 로고
    • Tensional homeostasis in dermal fibroblasts: Mechanical responses to mechanical loading in three-dimensional substrates
    • Brown RA, Prajapati R, McGrouther DA, Yannas IV, Eastwood M. 1998 Tensional homeostasis in dermal fibroblasts: mechanical responses to mechanical loading in three-dimensional substrates. J. Cell. Physiol. 175, 323-332. (doi:10.1002/(SICI)1097-4652(199806)175:3〈323::AID-JCP10〉3.0.CO;2-6)
    • (1998) J. Cell. Physiol. , vol.175 , pp. 323-332
    • Brown, R.A.1    Prajapati, R.2    McGrouther, D.A.3    Yannas, I.V.4    Eastwood, M.5
  • 21
    • 10944259814 scopus 로고    scopus 로고
    • Cellular stiffness response to external deformation: Tensional homeostasis in a single fibroblast
    • Mizutani T, Haga H, Kawabata K. 2004 Cellular stiffness response to external deformation: tensional homeostasis in a single fibroblast. Cell Motil. Cytoskeleton 59, 242-248. (doi:10.1002/cm.20037)
    • (2004) Cell Motil. Cytoskeleton , vol.59 , pp. 242-248
    • Mizutani, T.1    Haga, H.2    Kawabata, K.3
  • 22
    • 79960334368 scopus 로고    scopus 로고
    • High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells
    • Berginski ME, Vitriol EA, Hahn KM, Gomez SM. 2011 High-resolution quantification of focal adhesion spatiotemporal dynamics in living cells. PLoS ONE 6, e22025. (doi:10.1371/journal.pone.0022025)
    • (2011) PLoS ONE , vol.6 , pp. e22025
    • Berginski, M.E.1    Vitriol, E.A.2    Hahn, K.M.3    Gomez, S.M.4
  • 23
    • 0026778133 scopus 로고
    • The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
    • Ridley AJ, Hall A. 1992 The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399. (doi:10.1016/0092-8674(92)90163-7)
    • (1992) Cell , vol.70 , pp. 389-399
    • Ridley, A.J.1    Hall, A.2
  • 24
    • 0028961293 scopus 로고
    • Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A. 1995 Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62. (doi:10.1016/0092-8674(95)90370-4)
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 25
    • 80053561012 scopus 로고    scopus 로고
    • Altered osteogenic commitment of human mesenchymal stem cells by ERM protein-dependent modulation of cellular biomechanics
    • Titushkin I, Cho M. 2011 Altered osteogenic commitment of human mesenchymal stem cells by ERM protein-dependent modulation of cellular biomechanics. J. Biomech. 44, 2692-2698. (doi:10.1016/j.jbiomech.2011.07.024)
    • (2011) J. Biomech. , vol.44 , pp. 2692-2698
    • Titushkin, I.1    Cho, M.2
  • 26
    • 84869014728 scopus 로고    scopus 로고
    • Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and chondrogenic pathways
    • Mathieu PS, Loboa EG. 2012 Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and chondrogenic pathways. Tissue Eng. Part B 18, 436-444. (doi:10.1089/ten.teb.2012.0014)
    • (2012) Tissue Eng. Part B , vol.18 , pp. 436-444
    • Mathieu, P.S.1    Loboa, E.G.2
  • 27
    • 14644436314 scopus 로고    scopus 로고
    • A comparison of strain and fluid shear stress in stimulating bone cell responses - A computational and experimental study
    • McGarry JG, Klein-Nulend J, Mullender MG, Prendergast PJ. 2005 A comparison of strain and fluid shear stress in stimulating bone cell responses - a computational and experimental study. FASEB J. 19, 482-484.
    • (2005) FASEB J. , vol.19 , pp. 482-484
    • McGarry, J.G.1    Klein-Nulend, J.2    Mullender, M.G.3    Prendergast, P.J.4
  • 28
    • 84875723647 scopus 로고    scopus 로고
    • A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems
    • Vaughan TJ, Haugh MG, McNamara LM. 2013 A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems. J. R. Soc. Interface 10, 20120900. (doi:10.1098/rsif.2012.0900)
    • (2013) J. R. Soc. Interface , vol.10 , pp. 20120900
    • Vaughan, T.J.1    Haugh, M.G.2    McNamara, L.M.3
  • 29
    • 58149188069 scopus 로고    scopus 로고
    • A finite element prediction of strain on cells in a highly porous collagen-glycosaminoglycan scaffold
    • Stops AJ, McMahon LA, O'Mahoney D, Prendergast PJ, McHugh PE. 2008 A finite element prediction of strain on cells in a highly porous collagen-glycosaminoglycan scaffold. J. Biomech. Eng. 130, 061001. (doi:10.1115/1.2979873)
    • (2008) J. Biomech. Eng. , vol.130 , pp. 061001
    • Stops, A.J.1    McMahon, L.A.2    O'Mahoney, D.3    Prendergast, P.J.4    McHugh, P.E.5
  • 30
    • 84859368204 scopus 로고    scopus 로고
    • Transduction of strain to cells seeded onto scaffolds exposed to uniaxial stretching: A three dimensional finite element study
    • Stern AR, Stern MM, Van Dyke M. 2012 Transduction of strain to cells seeded onto scaffolds exposed to uniaxial stretching: a three dimensional finite element study. J. Mech. Med. Biol. 12, 1250022. (doi:10.1142/S0219519412004491)
    • (2012) J. Mech. Med. Biol. , vol.12 , pp. 1250022
    • Stern, A.R.1    Stern, M.M.2    Van Dyke, M.3
  • 33
    • 0005759897 scopus 로고    scopus 로고
    • Strain concentrations surrounding an ellipsoid model of lacunae and osteocytes
    • McCreadie BRSJH. 1997 Strain concentrations surrounding an ellipsoid model of lacunae and osteocytes. Comput. Methods Biomech. Biomed. Eng. 1, 61-68. (doi:10.1080/01495739708936695)
    • (1997) Comput. Methods Biomech. Biomed. Eng. , vol.1 , pp. 61-68
    • McCreadie, B.R.S.J.H.1
  • 34
    • 0035997021 scopus 로고    scopus 로고
    • Determination of cellular strains by combined atomic force microscopy and finite element modeling
    • Charras GT, Horton MA. 2002 Determination of cellular strains by combined atomic force microscopy and finite element modeling. Biophys. J. 83, 858-879. (doi:10.1016/S0006-3495(02)75214-4)
    • (2002) Biophys. J. , vol.83 , pp. 858-879
    • Charras, G.T.1    Horton, M.A.2
  • 35
    • 0036137722 scopus 로고    scopus 로고
    • Contribution of the nucleus to the mechanical properties of endothelial cells
    • Caille N, Thoumine O, Tardy Y, Meister J-J. 2002 Contribution of the nucleus to the mechanical properties of endothelial cells. J. Biomech. 35, 177-187. (doi:10.1016/S0021-9290(01)00201-9)
    • (2002) J. Biomech. , vol.35 , pp. 177-187
    • Caille, N.1    Thoumine, O.2    Tardy, Y.3    Meister, J.-J.4
  • 36
    • 0242322436 scopus 로고    scopus 로고
    • A three-dimensional viscoelastic model for cell deformation with experimental verification
    • Karcher H, Lammerding J, Huang HD, Lee RT, Kamm RD, Kaazempur-Mofrad MR. 2003 A three-dimensional viscoelastic model for cell deformation with experimental verification. Biophys. J. 85, 3336-3349. (doi:10.1016/S0006-3495(03)74753-5)
    • (2003) Biophys. J. , vol.85 , pp. 3336-3349
    • Karcher, H.1    Lammerding, J.2    Huang, H.D.3    Lee, R.T.4    Kamm, R.D.5    Kaazempur-Mofrad, M.R.6
  • 37
    • 27744502570 scopus 로고    scopus 로고
    • Determination of the Poisson's ratio of the cell: Recovery properties of chondrocytes after release from complete micropipette aspiration
    • Trickey WR, Baaijens FPT, Laursen TA, Alexopoulos LG, Guilak F. 2006 Determination of the Poisson's ratio of the cell: recovery properties of chondrocytes after release from complete micropipette aspiration. J. Biomech. 39, 78-87. (doi:10.1016/j.jbiomech.2004.11.006)
    • (2006) J. Biomech. , vol.39 , pp. 78-87
    • Trickey, W.R.1    Baaijens, F.P.T.2    Laursen, T.A.3    Alexopoulos, L.G.4    Guilak, F.5
  • 38
    • 84887582497 scopus 로고    scopus 로고
    • Experimental and computational investigation of the role of stress fiber contractility in the resistance of osteoblasts to compression
    • Weafer PP, Ronan W, Jarvis SP, McGarry JP. 2013 Experimental and computational investigation of the role of stress fiber contractility in the resistance of osteoblasts to compression. Bull. Math. Biol. 1, 1-20.
    • (2013) Bull. Math. Biol. , vol.1 , pp. 1-20
    • Weafer, P.P.1    Ronan, W.2    Jarvis, S.P.3    McGarry, J.P.4
  • 39
    • 84866667477 scopus 로고    scopus 로고
    • Numerical investigation of the active role of the actin cytoskeleton in the compression resistance of cells
    • Ronan W, Deshpande VS, McMeeking RM, McGarry JP. 2012 Numerical investigation of the active role of the actin cytoskeleton in the compression resistance of cells. J. Mech. Behav. Biomed. Mater. 14, 143-157. (doi:10.1016/j.jmbbm.2012.05.016)
    • (2012) J. Mech. Behav. Biomed. Mater. , vol.14 , pp. 143-157
    • Ronan, W.1    Deshpande, V.S.2    McMeeking, R.M.3    McGarry, J.P.4
  • 41
    • 58649124748 scopus 로고    scopus 로고
    • Image-based finite element modeling of alveolar epithelial cell injury during airway reopening
    • Dailey HL, Ricles LM, Yalcin HC, Ghadiali SN. 2009 Image-based finite element modeling of alveolar epithelial cell injury during airway reopening. J. Appl. Physiol. 106, 221-232. (doi:10.1152/japplphysiol.90688.2008)
    • (2009) J. Appl. Physiol. , vol.106 , pp. 221-232
    • Dailey, H.L.1    Ricles, L.M.2    Yalcin, H.C.3    Ghadiali, S.N.4
  • 42
    • 84866253248 scopus 로고    scopus 로고
    • Strain amplification in bone mechanobiology: A computational investigation of the in vivo mechanics of osteocytes
    • Verbruggen SWTJ, VaL MM. 2012 Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes. J. R. Soc. Interface 9, 2735-2744. (doi:10.1098/rsif.2012.0286)
    • (2012) J. R. Soc. Interface , vol.9 , pp. 2735-2744
    • Verbruggen, S.W.T.J.1    VaL, M.M.2
  • 43
    • 79955016325 scopus 로고    scopus 로고
    • Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds
    • Haugh MG, Murphy CM, McKiernan RC, Altenbuchner C, O'Brien FJ. 2011 Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds. Tissue Eng. A 17, 1201-1208. (doi:10.1089/ten.tea.2010.0590)
    • (2011) Tissue Eng. A , vol.17 , pp. 1201-1208
    • Haugh, M.G.1    Murphy, C.M.2    McKiernan, R.C.3    Altenbuchner, C.4    O'Brien, F.J.5
  • 44
    • 0020678843 scopus 로고
    • In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
    • Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. 1983 In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J. Cell Biol. 96, 191-198. (doi:10.1083/jcb.96.1.191)
    • (1983) J. Cell Biol. , vol.96 , pp. 191-198
    • Sudo, H.1    Kodama, H.A.2    Amagai, Y.3    Yamamoto, S.4    Kasai, S.5
  • 45
    • 0026690364 scopus 로고
    • Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: An in vitro model of osteoblast development
    • Quarles LD, Yohay DA, Lever LW, Caton R, Wenstrup RJ. 1992 Distinct proliferative and differentiated stages of murine MC3T3-E1 cells in culture: an in vitro model of osteoblast development. J. Bone Miner. Res. 7, 683-692. (doi:10.1002/jbmr.5650070613)
    • (1992) J. Bone Miner. Res. , vol.7 , pp. 683-692
    • Quarles, L.D.1    Yohay, D.A.2    Lever, L.W.3    Caton, R.4    Wenstrup, R.J.5
  • 46
    • 0034805319 scopus 로고    scopus 로고
    • Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells
    • Maeda T, Matsunuma A, Kawane T, Horiuchi N. 2001 Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells. Biochem. Biophys. Res. Commun. 280, 874-877. (doi:10.1006/bbrc.2000.4232)
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 874-877
    • Maeda, T.1    Matsunuma, A.2    Kawane, T.3    Horiuchi, N.4
  • 47
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. 1997 Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89, 747-754. (doi:10.1016/S0092-8674(00)80257-3)
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 48
    • 84904553831 scopus 로고    scopus 로고
    • Estrogen withdrawal from osteoblasts and osteocytes causes increased mineralization and apoptosis
    • Brennan MÁ, Haugh MG, O'Brien FJ, McNamara LM. 2000 Estrogen withdrawal from osteoblasts and osteocytes causes increased mineralization and apoptosis. Horm. Metab. Res. 46, 537-545. (doi:10.1055/s-0033-1363265)
    • (2000) Horm. Metab. Res. , vol.46 , pp. 537-545
    • Brennan, M.Á.1    Haugh, M.G.2    O'Brien, F.J.3    McNamara, L.M.4
  • 49
    • 0026875935 scopus 로고
    • An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments
    • Oliver WC, Pharr GM. 1992 An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments. J. Mater. Res. 7, 1564-1583. (doi:10.1557/JMR.1992.1564)
    • (1992) J. Mater. Res. , vol.7 , pp. 1564-1583
    • Oliver, W.C.1    Pharr, G.M.2
  • 51
    • 0033402884 scopus 로고    scopus 로고
    • Cytoindentation for obtaining cell biomechanical properties
    • Shin D, Athanasiou K. 1999 Cytoindentation for obtaining cell biomechanical properties. J. Orthop. Res. 17, 880-890. (doi:10.1002/jor.1100170613)
    • (1999) J. Orthop. Res. , vol.17 , pp. 880-890
    • Shin, D.1    Athanasiou, K.2
  • 52
    • 7744230624 scopus 로고    scopus 로고
    • Analysis of nonlinear responses of adherent epithelial cells probed by magnetic bead twisting: A finite element model based on a homogenization approach
    • Ohayon J, Tracqui P, Fodil R, Féréol S, Laurent VM, Planus E, Isabey D. 2004 Analysis of nonlinear responses of adherent epithelial cells probed by magnetic bead twisting: a finite element model based on a homogenization approach. J. Biomech. Eng. 126, 685-698. (doi:10.1115/1.1824136)
    • (2004) J. Biomech. Eng. , vol.126 , pp. 685-698
    • Ohayon, J.1    Tracqui, P.2    Fodil, R.3    Féréol, S.4    Laurent, V.M.5    Planus, E.6    Isabey, D.7
  • 53
    • 0035997133 scopus 로고    scopus 로고
    • Buckling of actin stress fibers: A new wrinkle in the cytoskeletal tapestry
    • Costa KD, Hucker WJ, Yin FCP. 2002 Buckling of actin stress fibers: a new wrinkle in the cytoskeletal tapestry. Cell Motil. Cytoskeleton 52, 266-274. (doi:10.1002/cm.10056)
    • (2002) Cell Motil. Cytoskeleton , vol.52 , pp. 266-274
    • Costa, K.D.1    Hucker, W.J.2    Yin, F.C.P.3
  • 54
    • 19944428596 scopus 로고    scopus 로고
    • Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
    • Yeung T et al. 2005 Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton 60, 24-34. (doi:10.1002/cm.20041)
    • (2005) Cell Motil. Cytoskeleton , vol.60 , pp. 24-34
    • Yeung, T.1
  • 55
    • 84862777456 scopus 로고    scopus 로고
    • Reliable measurement of elastic modulus of cells by nanoindentation in an atomic force microscope
    • Zhou ZL, Ngan AHW, Tang B, Wang AX. 2012 Reliable measurement of elastic modulus of cells by nanoindentation in an atomic force microscope. J. Mech. Behav. Biomed. Mater. 8, 134-142. (doi:10.1016/j.jmbbm.2011.11.010)
    • (2012) J. Mech. Behav. Biomed. Mater. , vol.8 , pp. 134-142
    • Zhou, Z.L.1    Ngan, A.H.W.2    Tang, B.3    Wang, A.X.4
  • 57
    • 0034736609 scopus 로고    scopus 로고
    • Substrate dependent differences in morphology and elasticity of living osteoblasts investigated by atomic force microscopy
    • Domke J, Dannöhl S, Parak WJ, Müller O, Aicher WK, Radmacher M. 2000 Substrate dependent differences in morphology and elasticity of living osteoblasts investigated by atomic force microscopy. Colloids Surf. B Biointerfaces 19, 367-379. (doi:10.1016/S0927-7765(00)00145-4)
    • (2000) Colloids Surf. B Biointerfaces , vol.19 , pp. 367-379
    • Domke, J.1    Dannöhl, S.2    Parak, W.J.3    Müller, O.4    Aicher, W.K.5    Radmacher, M.6
  • 58
    • 79953861194 scopus 로고    scopus 로고
    • Cell shape and substrate rigidity both regulate cell stiffness
    • Tee S-Y, Fu J, Chen Christopher S, Janmey Paul A. 2011 Cell shape and substrate rigidity both regulate cell stiffness. Biophys. J. 100, L25-L27. (doi:10.1016/j.bpj.2010.12.3744)
    • (2011) Biophys. J. , vol.100 , pp. L25-L27
    • Tee, S.-Y.1    Fu, J.2    Chen Christopher, S.3    Janmey Paul, A.4
  • 59
    • 0025062973 scopus 로고
    • Osteocyte differentiation in the tibia of newborn rabbit: An ultrastructural study of the formation of cytoplasmic processes
    • Palumbo C, Palazzini S, Zaffe D, Marotti G. 1990 Osteocyte differentiation in the tibia of newborn rabbit: an ultrastructural study of the formation of cytoplasmic processes. Cells Tissues Organs 137, 350-358. (doi:10.1159/000146907)
    • (1990) Cells Tissues Organs , vol.137 , pp. 350-358
    • Palumbo, C.1    Palazzini, S.2    Zaffe, D.3    Marotti, G.4
  • 60
    • 0030967875 scopus 로고    scopus 로고
    • Dexamethasone enhances differentiation of human osteoblastic cells in vitro
    • Yamanouchi K, Gotoh Y, Nagayama M. 1997 Dexamethasone enhances differentiation of human osteoblastic cells in vitro. J. Bone Miner. Metab. 15, 23-29. (doi:10.1007/BF02439451)
    • (1997) J. Bone Miner. Metab. , vol.15 , pp. 23-29
    • Yamanouchi, K.1    Gotoh, Y.2    Nagayama, M.3
  • 61
    • 0029881459 scopus 로고    scopus 로고
    • Osteocyte density changes in aging and osteoporosis
    • Mullender MG, van der Meer DD, Huiskes R, Lips P. 1996 Osteocyte density changes in aging and osteoporosis. Bone 18, 109-113. (doi:10.1016/8756-3282(95)00444-0)
    • (1996) Bone , vol.18 , pp. 109-113
    • Mullender, M.G.1    Van Der Meer, D.D.2    Huiskes, R.3    Lips, P.4
  • 62
    • 18144374198 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of chick calvarial osteocytes and their cell processes using confocal microscopy
    • Sugawara Y, Kamioka H, Honjo T, Tezuka K-i, Takano-Yamamoto T. 2005 Three-dimensional reconstruction of chick calvarial osteocytes and their cell processes using confocal microscopy. Bone 36, 877-883. (doi:10.1016/j.bone.2004.10.008)
    • (2005) Bone , vol.36 , pp. 877-883
    • Sugawara, Y.1    Kamioka, H.2    Honjo, T.3    Tezuka, K.-I.4    Takano-Yamamoto, T.5
  • 63
    • 0031668242 scopus 로고    scopus 로고
    • Osteocyte shape is dependent on actin filaments and osteocyte processes are unique actin-rich projections
    • Tanaka Kamioka K, Kamioka H, Ris H, Lim S-S. 1998 Osteocyte shape is dependent on actin filaments and osteocyte processes are unique actin-rich projections. J. Bone Miner. Res. 13, 1555-1568. (doi:10.1359/jbmr.1998.13.10.1555)
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 1555-1568
    • Tanaka Kamioka, K.1    Kamioka, H.2    Ris, H.3    Lim, S.-S.4
  • 64
    • 78049426449 scopus 로고    scopus 로고
    • Mechano-topographic modulation of stem cell nuclear shape on nanofibrous scaffolds
    • Nathan AS, Baker BM, Nerurkar NL, Mauck RL. 2011 Mechano-topographic modulation of stem cell nuclear shape on nanofibrous scaffolds. Acta Biomater. 7, 57-66. (doi:10.1016/j.actbio.2010.08.007)
    • (2011) Acta Biomater. , vol.7 , pp. 57-66
    • Nathan, A.S.1    Baker, B.M.2    Nerurkar, N.L.3    Mauck, R.L.4
  • 65
    • 0037133313 scopus 로고    scopus 로고
    • Engineering gene expression and protein synthesis by modulation of nuclear shape
    • Thomas HC, Collier JH, Sfeir CS, Healy KE. 2002 Engineering gene expression and protein synthesis by modulation of nuclear shape. Proc. Natl Acad. Sci. USA 99, 1972-1977. (doi:10.1073/pnas.032668799)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 1972-1977
    • Thomas, H.C.1    Collier, J.H.2    Sfeir, C.S.3    Healy, K.E.4
  • 66
    • 84865373665 scopus 로고    scopus 로고
    • Decoupling substrate stiffness, spread area, and micropost density: A close spatial relationship between traction forces and focal adhesions
    • Han Sangyoon J, Bielawski Kevin S, Ting Lucas H, Rodriguez Marita L, Sniadecki Nathan J. 2012 Decoupling substrate stiffness, spread area, and micropost density: a close spatial relationship between traction forces and focal adhesions. Biophys. J. 103, 640-648. (doi:10.1016/j.bpj.2012.07.023)
    • (2012) Biophys. J. , vol.103 , pp. 640-648
    • Han Sangyoon, J.1    Bielawski Kevin, S.2    Ting Lucas, H.3    Rodriguez Marita, L.4    Sniadecki Nathan, J.5
  • 67
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher DE, Janmey P, Wang Y-l. 2005 Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139-1143. (doi:10.1126/science.1116995)
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.-L.3
  • 68
    • 3042558631 scopus 로고    scopus 로고
    • Formation of focal adhesions on fibronectin promotes fluid shear stress induction of COX-2 and PGE2 release in MC3T3-E1 osteoblasts
    • Ponik SM, Pavalko FM. 2004 Formation of focal adhesions on fibronectin promotes fluid shear stress induction of COX-2 and PGE2 release in MC3T3-E1 osteoblasts. J. Appl. Physiol. 97, 135-142. (doi:10.1152/japplphysiol.01260.2003)
    • (2004) J. Appl. Physiol. , vol.97 , pp. 135-142
    • Ponik, S.M.1    Pavalko, F.M.2
  • 69
    • 33846455438 scopus 로고    scopus 로고
    • The regulation of integrin-mediated osteoblast focal adhesion and focal adhesion kinase expression by nanoscale topography
    • Lim JY, Dreiss AD, Zhou Z, Hansen JC, Siedlecki CA, Hengstebeck RW, Cheng J, Winograd N, Donahue HJ. 2007 The regulation of integrin-mediated osteoblast focal adhesion and focal adhesion kinase expression by nanoscale topography. Biomaterials 28, 1787-1797. (doi:10.1016/j.biomaterials.2006.12.020)
    • (2007) Biomaterials , vol.28 , pp. 1787-1797
    • Lim, J.Y.1    Dreiss, A.D.2    Zhou, Z.3    Hansen, J.C.4    Siedlecki, C.A.5    Hengstebeck, R.W.6    Cheng, J.7    Winograd, N.8    Donahue, H.J.9
  • 70
    • 3142755633 scopus 로고    scopus 로고
    • Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation
    • Boutahar N, Guignandon A, Vico L, Lafage-Proust M-H. 2004 Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation. J. Biol. Chem. 279, 30 588-30 599. (doi:10.1074/jbc.M313244200)
    • (2004) J. Biol. Chem. , vol.279 , pp. 30588-30599
    • Boutahar, N.1    Guignandon, A.2    Vico, L.3    Lafage-Proust, M.-H.4
  • 71
    • 84878379005 scopus 로고    scopus 로고
    • Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal stem cell adhesion
    • Milan JL et al. 2013 Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal stem cell adhesion. Eur. Cells Mater. 25, 97-113.
    • (2013) Eur. Cells Mater. , vol.25 , pp. 97-113
    • Milan, J.L.1
  • 72
    • 59349100031 scopus 로고    scopus 로고
    • Measurement and finite element modeling of the force balance in the vertical section of adhering vascular endothelial cells
    • Deguchi S, Fukamachi H, Hashimoto K, Iio K, Tsujioka K. 2009 Measurement and finite element modeling of the force balance in the vertical section of adhering vascular endothelial cells. J. Mech. Behav. Biomed. Mater. 2, 173-185. (doi:10.1016/j.jmbbm.2008.07.003)
    • (2009) J. Mech. Behav. Biomed. Mater. , vol.2 , pp. 173-185
    • Deguchi, S.1    Fukamachi, H.2    Hashimoto, K.3    Iio, K.4    Tsujioka, K.5
  • 74
    • 84883201360 scopus 로고    scopus 로고
    • Finite-element modeling of viscoelastic cells during high-frequency cyclic strain
    • Milner JS, Grol MW, Beaucage KL, Dixon SJ, Holdsworth DW. 2012 Finite-element modeling of viscoelastic cells during high-frequency cyclic strain. J. Funct. Biomater. 3, 209-224. (doi:10.3390/jfb3010209)
    • (2012) J. Funct. Biomater. , vol.3 , pp. 209-224
    • Milner, J.S.1    Grol, M.W.2    Beaucage, K.L.3    Dixon, S.J.4    Holdsworth, D.W.5
  • 75
    • 84881229322 scopus 로고    scopus 로고
    • Cell cytoskeletal changes effected by static compressive stress lead to changes in the contractile properties of tissue regenerative collagen membranes
    • Gellynck K, Shah R, Deng D, Parkar M, Liu W, Knowles JC, Buxton P. 2013 Cell cytoskeletal changes effected by static compressive stress lead to changes in the contractile properties of tissue regenerative collagen membranes. Eur. Cell Mater. 25, 317-325.
    • (2013) Eur. Cell Mater. , vol.25 , pp. 317-325
    • Gellynck, K.1    Shah, R.2    Deng, D.3    Parkar, M.4    Liu, W.5    Knowles, J.C.6    Buxton, P.7
  • 77
    • 84872198744 scopus 로고    scopus 로고
    • Membrane tension homeostasis of epithelial cells through surface area regulation in response to osmotic stress
    • Pietuch A, Brückner BR, Janshoff A. 2013 Membrane tension homeostasis of epithelial cells through surface area regulation in response to osmotic stress. Biochim. Biophys. Acta Mol. Cell Res. 1833, 712-722. (doi:10.1016/j.bbamcr.2012.11.006)
    • (2013) Biochim. Biophys. Acta Mol. Cell Res. , vol.1833 , pp. 712-722
    • Pietuch, A.1    Brückner, B.R.2    Janshoff, A.3
  • 78
    • 45849114072 scopus 로고    scopus 로고
    • Loss of homeostatic tension induces apoptosis in tendon cells: An in vitro study
    • Egerbacher M, Arnoczky S, Caballero O, Lavagnino M, Gardner K. 2008 Loss of homeostatic tension induces apoptosis in tendon cells: an in vitro study. Clin. Orthop. Relat. Res. 466, 1562-1568. (doi:10.1007/s11999-008-0274-8)
    • (2008) Clin. Orthop. Relat. Res. , vol.466 , pp. 1562-1568
    • Egerbacher, M.1    Arnoczky, S.2    Caballero, O.3    Lavagnino, M.4    Gardner, K.5
  • 79
    • 33847767113 scopus 로고    scopus 로고
    • Mechanotransduction and endothelial cell homeostasis: The wisdom of the cell
    • Chien S. 2007 Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell. Am. J. Physiol. Heart Circ. Physiol. 292, H1209-H1224. (doi:10.1152/ajpheart.01047.2006)
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.292 , pp. H1209-H1224
    • Chien, S.1
  • 81
    • 0031012936 scopus 로고    scopus 로고
    • Bone mass homeostasis and bisphosphonate action
    • Rodan GA. 1997 Bone mass homeostasis and bisphosphonate action. Bone 20, 1-4. (doi:10.1016/S8756-3282(96)00318-3)
    • (1997) Bone , vol.20 , pp. 1-4
    • Rodan, G.A.1
  • 82
    • 34247495109 scopus 로고    scopus 로고
    • Mechanosensation and transduction in osteocytes
    • Bonewald LF. 2006 Mechanosensation and transduction in osteocytes. Bonekey Rep. 3, 7-15.
    • (2006) Bonekey Rep. , vol.3 , pp. 7-15
    • Bonewald, L.F.1
  • 84
    • 33645773666 scopus 로고    scopus 로고
    • Local force and geometry sensing regulate cell functions
    • Vogel V, Sheetz M. 2006 Local force and geometry sensing regulate cell functions. Nat. Rev. Mol. Cell Biol. 7, 265-275. (doi:10.1038/nrm1890)
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 265-275
    • Vogel, V.1    Sheetz, M.2
  • 85
    • 58049220350 scopus 로고    scopus 로고
    • Mechanotransduction in development: A growing role for contractility
    • Wozniak MA, Chen CS. 2009 Mechanotransduction in development: a growing role for contractility. Nat. Rev. Mol. Cell Biol. 10, 34-43. (doi:10.1038/nrm2592)
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 34-43
    • Wozniak, M.A.1    Chen, C.S.2
  • 86
    • 77956064817 scopus 로고    scopus 로고
    • Cell adhesion: Integrating cytoskeletal dynamics and cellular tension
    • Parsons JT, Horwitz AR, Schwartz MA. 2010 Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat. Rev. Mol. Cell Biol. 11, 633-643. (doi:10.1038/nrm2957)
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 633-643
    • Parsons, J.T.1    Horwitz, A.R.2    Schwartz, M.A.3
  • 87
    • 0037113916 scopus 로고    scopus 로고
    • The RhoA-binding protein, Rhophilin-2, regulates actin cytoskeleton organization
    • Peck JW, Oberst M, Bouker KB, Bowden E, Burbelo PD. 2002 The RhoA-binding protein, Rhophilin-2, regulates actin cytoskeleton organization. J. Biol. Chem. 277, 43 924-43 932. (doi:10.1074/jbc.M203569200)
    • (2002) J. Biol. Chem. , vol.277 , pp. 43924-43932
    • Peck, J.W.1    Oberst, M.2    Bouker, K.B.3    Bowden, E.4    Burbelo, P.D.5
  • 88
    • 79952779502 scopus 로고    scopus 로고
    • Rho GTPases and their role in organizing the actin cytoskeleton
    • Sit ST, Manser E. 2011 Rho GTPases and their role in organizing the actin cytoskeleton. J. Cell Sci. 124, 679-683. (doi:10.1242/jcs.064964)
    • (2011) J. Cell Sci. , vol.124 , pp. 679-683
    • Sit, S.T.1    Manser, E.2
  • 89
    • 3242789407 scopus 로고    scopus 로고
    • Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: Evidence for two forms of spine motility
    • Tashiro A, Yuste R. 2004 Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: evidence for two forms of spine motility. Mol. Cell. Neurosci. 26, 429-440. (doi:10.1016/j.mcn.2004.04.001)
    • (2004) Mol. Cell. Neurosci. , vol.26 , pp. 429-440
    • Tashiro, A.1    Yuste, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.