Osteocyte density changes in aging and osteoporosis

Bone

Volumn 18, Issue 2, 1996, Pages 109-113

  Mullender, M G ^a   Van Der Meer, D D ^a   Huiskes, R ^a   Lips, P ^b  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Osteocyte; Osteocyte lacunar number; Osteocyte lacunar size; Osteoporosis; Trabecular bone

Indexed keywords

ADULT; AGED; AGING; ARTICLE; BONE DENSITY; BONE REMODELING; CELL DEATH; CONTROLLED STUDY; FEMALE; FRACTURE; HUMAN; HUMAN TISSUE; ILIAC CREST; MAJOR CLINICAL STUDY; MALE; OSTEOBLAST; OSTEOCYTE; OSTEOPOROSIS; TRABECULAR BONE;

EID: 0029881459     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/8756-3282(95)00444-0     Document Type: Article

References (34)

1. Aarden, E. M., Burger, E. H., and Nijweide, P. J. Function of osteocytes in bone. J Cell Biochem 55:287-299; 1994.
2. Baud, C. A. and Auil, E. Osteocyte differential count in normal human alveolar bone. Acta Anat 78:321-327; 1971.
3. Cowin, S. C., Moss-Salentijn, L., and Moss, M. L. Candidates for the mechanosensory system in bone. J Biomech Eng 113:191-197; 1991.
4. Darby, A. J. and Meunier, P. J. Mean wall thickness and formation periods of trabecular bone packets in idiopathic osteoporosis. Calcif Tissue Int 33:199-204; 1981.
5. Dunstan, C. R., Somers, N. M., and Evans, R. A. Osteocyte death and hip fracture. Calcif Tissue Int 53(suppl. 1):S113-S117; 1993.
6. Eriksen, E. F., Hodgson, S. F., Eastell, R., Cedel, S. L., O'Fallon, W. M., and Riggs, B. L. Cancellous bone remodeling in type I (postmenopausal) osteoporosis: quantitative assessment of rates of formation, resorption, and bone loss at tissue and cellular levels. J Bone Miner Res 5:311; 1990.
7. Eriksen, E. F. and Kassem, M. The cellular basis of bone remodeling. Triangle, Sandoz Journal of Medical Science 31:45-57; 1992.
8. Eriksen, E. F., Langdahl, B., and Kassem, M. The cellular basis of osteoporosis. Spine State of the Art Reviews 8:23-62; 1994.
9. Frost, H. M. In vivo osteocyte death. J Bone Jt Surg 2442-A:138-143; 1960.
10. Frost, H. M. Vital biomechanics: proposed general concepts for skeletal adaptations to mechanical usage. Calcif Tissue Int 42:145-156; 1988.
11. Gundersen, H. J. G. Steriology of arbitrary particles. J Microsc 143:3-45; 1986.
12. Hobdell, M. H., and Howe, C. E. Variation in bone matrix volume associated with osteocyte lacunae in mammalian and reptilian bone. Israel J Med Sci 7:492-493; 1971.
13. Kenzora, J. E., Steele, R. E., Yosipovitch, Z. H., and Glimcher, M. J. Experimental osteonecrosis of the femoral head in adult rabbits. Clin Orthop 130:8; 1978.
14. Klein-Nulend, J., Van der Plas, A., Semeins, C. M., Ajubi, N. E., Frangos, J. A., Nijweide, P. J., and Burger, E. H. Sensitivity of osteocytes to biomechanical stress in vitro. FASEB J 9:441-445; 1995.
15. Lanyon, L. E. Osteocytes, strain detection, bone modeling and remodeling. Calcif Tissue Int 53(suppl. 1):S102-S106; 1993.
16. Lips, P., Coupron, P., and Meunier, P. J. Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age. Calcif Tissue Res 26:13-17; 1978.
17. Marotti, G., Cané, V., Palazzini, S., and Palumbo, C. Structure-function relationships in the osteocyte. Ital J Miner Electrolyte Metab 4:93-106; 1990.
18. Marotti, G., Ferretti, M., Muglia, M. A., Palumbo, C., and Palazzini, S. A quantitative evaluation of osteoblast-osteocyte relationships on growing endosteal surface of rabbit tibiae. Bone 13:363-368; 1992.
19. Mullender, M. G. and Huiskes, R. A proposal for the regulatory mechanism of Wolff's law. J Orthop Res 13:503-512; 1995.
20. Mullender, M. G., Huiskes, R., and Weinans, H. A physiological approach to the simulation of bone remodeling as a self-organizational control process [technical note] J Biomech 27:1389-1394; 1994.
21. Nefussi, J. R., Sautier, J. M., Nicolas, V., and Forest, N. How osteoblasts become osteocytes: A decreasing matrix forming process. J Biol Buccale 19:75-82; 1991.
22. Palumbo, C., Palazzini, S., and Marotti, G. Morphological study of intercellular junctions during osteocyte differentiation. Bone 11:401-406; 1990.
23. Palumbo, C., Palazzini, S., Zaffe, D., and Marotti, G. Osteocyte differentiation in the tibia of newborn rabbit: an ultrastructural study of the formation of cytoplasmic processes. Acta Anal 137:350-358; 1990.
24. Parfitt, A. M., Mathews, C. H. E., Villanueva, A. R., and Kleerekoper, M. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and osteoporosis. J Clin Invest 72:1396-1409; 1983.
25. Rodan, G. A. Mechanical loading, estrogen deficiency, and the coupling of bone formation to bone resorption. J Bone Miner Res 6:527-530; 1991.
26. Shih, M. S., Cook, M. A., Spence, C. A., Palnitkar, S., McElroy, H., and Parfitt, A. M. Relationship between bone formation rate and osteoblast surface on different subdivisions of the endosteal envelope in aging and osteoporosis. Bone 14:519-521; 1993.
27. Sissons, H. A. and O'Connor, P. Quantitative histology of osteocyte lacunae in time normal human cortical bone. Calcif Tissue Res 22(suppl. 1):530-533; 1977.
28. Sissons, H. A., Kelman, G. J., Ling, L., Marotti, G., Canè, V., and Muglia, M. A. A light and scanning electron microscopic study of osteocyte activity in calcium-deficient rats. Calcif Tissue Int 46:33-37; 1990.
29. Sissons, H. A., Kelman, G. J., and Marotti, G. Mechanisms of bone resorption in calcium-deficient rats. Calcif Tissue Int 36:711-721; 1984.
30. Sterio, D. C. The unbiased estimator of number and sizes of arbitrary particles using the disector. J Microsc 134:127-136; 1984.
31. Uitewaal, P. J. M., Lips, P., and Netelenbos, J. C. An analysis of bone structure in patients with hip fracture. Bone Miner 3:63-73; 1987.
32. Wong, S. Y. P., Kariks, J., Evans, R. A., Dunstan, C. R., and Hills, E. The effect of age on bone composition and viability in the femoral head. J Bone Jt Surg 67A:274-283; 1985.
33. Wong, S. Y. P., Evans, R. A., Needs, C., Dunstan, C. R., Hills, E., and Garvan, J. The pathogenesis of osteoarthritis of the hip. Clin Orthop Rel Res 214:305-312; 1987.
34. Wright, P. H., Jowsey, J. O., and Robb, R. A. Osteocyte lacunar area in normal bone, hyperparathyroidism, renal disease, and osteoporosis. Surg Forum 29:558-559; 1978.