Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: Protective effect of CNF1

Free Radical Biology and Medicine

Volumn 83, Issue , 2015, Pages 167-177

  De Filippis, Bianca ^a   Valenti, Daniela ^b   De Bari, Lidia ^b   De Rasmo, Domenico ^b   Musto, Mattia ^a   Fabbri, Alessia ^a   Ricceri, Laura ^a   Fiorentini, Carla ^a   Laviola, Giovanni ^a   Vacca, Rosa Anna ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b CNR   (Italy)

Author keywords

Energy metabolism; Free radicals; Mitochondrial dysfunction; Oxidative stress; Reactive oxygen species; Rett syndrome

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME C OXIDASE; CYTOTOXIC NECROTIZING FACTOR 1; FREE RADICAL; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID; UBIQUINOL CYTOCHROME C REDUCTASE; BACTERIAL TOXIN; ESCHERICHIA COLI PROTEIN; METHYL CPG BINDING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; BRAIN; BRAIN DISEASE; CELL FUNCTION; CEREBELLUM; CONTROLLED STUDY; ENERGY RESOURCE; ENZYME PHOSPHORYLATION; FEMALE; HETEROZYGOTE; MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATORY CHAIN; MITOCHONDRION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RESPIRATORY CHAIN; RETT SYNDROME; SYNTHESIS; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; ELECTRON TRANSPORT; GENETICS; HUMAN; IMMUNOBLOTTING; KNOCKOUT MOUSE; MALE; METABOLISM; MITOCHONDRIAL MEMBRANE; MUTATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); MUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; BACTERIAL TOXINS; BRAIN; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX II; ESCHERICHIA COLI PROTEINS; FEMALE; FREE RADICALS; HUMANS; IMMUNOBLOTTING; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MUTATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENOTYPE; REACTIVE OXYGEN SPECIES; RETT SYNDROME;

EID: 84927129741     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.02.014     Document Type: Article

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