Impairment of F1F0-ATPase, adenine nucleotide translocator and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy

Biochemical Journal

Volumn 431, Issue 2, 2010, Pages 299-310

  Valenti, Daniela ^a   Tullo, Apollonia ^a   Caratozzolo, Mariano F ^a   Merafina, Riccardo S ^a   Scartezzini, Paolo ^b   Marra, Ersilia ^a   Vacca, Rosa A ^a  

^a CNR   (Italy)

^b Galliera Hospitals ^*  (Italy)

Author keywords

Adenine nucleotide translocator (ANT); Adenylate kinase; cAMP level; Down's syndrome; F1F 0 ATPase; Mitochondrion

Indexed keywords

ADENYLATE KINASE; CAMP LEVEL; DOWN'S SYNDROME; F1F 0-ATPASE; TRANSLOCATORS;

CELL CULTURE; CHROMOSOMES; FETAL MONITORING; FIBROBLASTS; GENE EXPRESSION; LASER TISSUE INTERACTION; METABOLISM; NUCLEOTIDES; PROTEINS;

MITOCHONDRIA;

ADENINE NUCLEOTIDE TRANSLOCASE; ADENYLATE KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP; LACTIC ACID; MITOCHONDRIAL DNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ARTICLE; CHROMOSOME 21; DOWN SYNDROME; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SKIN FIBROBLAST; TRISOMY; BIOSYNTHESIS; CELL LINE; CELL RESPIRATION; ENERGY METABOLISM; ENZYMOLOGY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLISM; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION; PATHOLOGY; SKIN;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; CELL LINE; CELL RESPIRATION; CHROMOSOMES, HUMAN, PAIR 21; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA, MITOCHONDRIAL; ENERGY METABOLISM; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KINETICS; LACTIC ACID; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; OXIDATIVE PHOSPHORYLATION; PROTON-TRANSLOCATING ATPASES; SKIN; TRISOMY;

EID: 77957897553     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100581     Document Type: Article

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