-
1
-
-
0242551584
-
Homing and cellular traffic in lymph nodes
-
von Andrian, U.H., Mempel, T.R. Homing and cellular traffic in lymph nodes. Nat. Rev. Immunol. 3, 867-878 (2003).
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 867-878
-
-
Von Andrian, U.H.1
Mempel, T.R.2
-
2
-
-
79957686777
-
CD4+ T cells support cytotoxic T lymphocyte priming by controlling lymph node input
-
Kumamoto, Y., Mattei, L.M., Sellers, S., Payne, G.W., Iwasaki, A. CD4+ T cells support cytotoxic T lymphocyte priming by controlling lymph node input. Proc. Natl. Acad. Sci. USA 108, 8749-8754 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 8749-8754
-
-
Kumamoto, Y.1
Mattei, L.M.2
Sellers, S.3
Payne, G.W.4
Iwasaki, A.5
-
3
-
-
77952747811
-
CD11chi dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes
-
Tzeng, T.C. et al. CD11chi dendritic cells regulate the re-establishment of vascular quiescence and stabilization after immune stimulation of lymph nodes. J. Immunol. 184, 4247-4257 (2010).
-
(2010)
J. Immunol.
, vol.184
, pp. 4247-4257
-
-
Tzeng, T.C.1
-
4
-
-
82755170400
-
Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells
-
Chyou, S. et al. Coordinated regulation of lymph node vascular-stromal growth first by CD11c+ cells and then by T and B cells. J. Immunol. 187, 5558-5567 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 5558-5567
-
-
Chyou, S.1
-
5
-
-
78649510272
-
The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs
-
Turley, S.J., Fletcher, A.L., Elpek, K.G. The stromal and haematopoietic antigen-presenting cells that reside in secondary lymphoid organs. Nat. Rev. Immunol. 10, 813-825 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 813-825
-
-
Turley, S.J.1
Fletcher, A.L.2
Elpek, K.G.3
-
6
-
-
84871424854
-
Stromal and hematopoietic cells in secondary lymphoid organs: Partners in immunity
-
Malhotra, D., Fletcher, A.L., Turley, S.J. Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity. Immunol. Rev. 251, 160-176 (2013).
-
(2013)
Immunol. Rev.
, vol.251
, pp. 160-176
-
-
Malhotra, D.1
Fletcher, A.L.2
Turley, S.J.3
-
7
-
-
84859926294
-
Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks
-
Malhotra, D. et al. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nat. Immunol. 13, 499-510 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 499-510
-
-
Malhotra, D.1
-
8
-
-
35548975191
-
Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells
-
Link, A. et al. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat. Immunol. 8, 1255-1265 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1255-1265
-
-
Link, A.1
-
9
-
-
33845455093
-
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes
-
Bajénoff, M. et al. Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity 25, 989-1001 (2006).
-
(2006)
Immunity
, vol.25
, pp. 989-1001
-
-
Bajénoff, M.1
-
10
-
-
12444297666
-
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node
-
Sixt, M. et al. The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity 22, 19-29 (2005).
-
(2005)
Immunity
, vol.22
, pp. 19-29
-
-
Sixt, M.1
-
11
-
-
34548599933
-
Complement receptors CD21 and CD35 in humoral immunity
-
Roozendaal, R., Carroll, M.C. Complement receptors CD21 and CD35 in humoral immunity. Immunol. Rev. 219, 157-166 (2007).
-
(2007)
Immunol. Rev.
, vol.219
, pp. 157-166
-
-
Roozendaal, R.1
Carroll, M.C.2
-
12
-
-
84873339567
-
Podoplanin: Emerging functions in development, the immune system, and cancer
-
Astarita, J.L., Acton, S.E., Turley, S.J. Podoplanin: emerging functions in development, the immune system, and cancer. Front. Immunol. 3, 283 (2012).
-
(2012)
Front. Immunol.
, vol.3
, pp. 283
-
-
Astarita, J.L.1
Acton, S.E.2
Turley, S.J.3
-
13
-
-
0041312675
-
T1a/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema
-
Schacht, V. et al. T1a/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. EMBO J. 22, 3546-3556 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 3546-3556
-
-
Schacht, V.1
-
14
-
-
76749148097
-
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation
-
Uhrin, P. et al. Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood 115, 3997-4005 (2010).
-
(2010)
Blood
, vol.115
, pp. 3997-4005
-
-
Uhrin, P.1
-
15
-
-
33846188563
-
The potential role of podoplanin in tumour invasion
-
Wicki, A., Christofori, G. The potential role of podoplanin in tumour invasion. Br. J. Cancer 96, 1-5 (2007).
-
(2007)
Br. J. Cancer
, vol.96
, pp. 1-5
-
-
Wicki, A.1
Christofori, G.2
-
16
-
-
41649113697
-
Renal cells activate the platelet receptor CLEC-2 through podoplanin
-
Christou, C.M. et al. Renal cells activate the platelet receptor CLEC-2 through podoplanin. Biochem. J. 411, 133-140 (2008).
-
(2008)
Biochem. J.
, vol.411
, pp. 133-140
-
-
Christou, C.M.1
-
17
-
-
79960645812
-
Novel platelet activation receptor CLEC-2: From discovery to prospects
-
Suzuki-Inoue, K., Inoue, O., Ozaki, Y. Novel platelet activation receptor CLEC-2: from discovery to prospects. J. Thromb. Haemost. 9, 44-55 (2011).
-
(2011)
J. Thromb. Haemost.
, vol.9
, pp. 44-55
-
-
Suzuki-Inoue, K.1
Inoue, O.2
Ozaki, Y.3
-
18
-
-
84865401654
-
Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2
-
Acton, S.E. et al. Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2. Immunity 37, 276-289 (2012).
-
(2012)
Immunity
, vol.37
, pp. 276-289
-
-
Acton, S.E.1
-
19
-
-
84885624688
-
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2
-
Herzog, B.H. et al. Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2. Nature 502, 105-109 (2014).
-
(2014)
Nature
, vol.502
, pp. 105-109
-
-
Herzog, B.H.1
-
20
-
-
84892923313
-
Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life
-
Hess, P.R. et al. Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life. J. Clin. Invest. 124, 273-284 (2014).
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 273-284
-
-
Hess, P.R.1
-
21
-
-
84901408061
-
CLEC-2 is required for development and maintenance of lymph nodes
-
Bénézech, C. et al. CLEC-2 is required for development and maintenance of lymph nodes. Blood 123, 3200-3207 (2014).
-
(2014)
Blood
, vol.123
, pp. 3200-3207
-
-
Bénézech, C.1
-
22
-
-
0037565445
-
Dendritic cell function in vivo during the steady state: A role in peripheral tolerance
-
Steinman, R.M. et al. Dendritic cell function in vivo during the steady state: a role in peripheral tolerance. Ann. NY Acad. Sci. 987, 15-25 (2003).
-
(2003)
Ann. NY Acad. Sci.
, vol.987
, pp. 15-25
-
-
Steinman, R.M.1
-
23
-
-
33751539322
-
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition
-
Martín-Villar, E. et al. Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition. J. Cell Sci. 119, 4541-4553 (2006).
-
(2006)
J. Cell Sci.
, vol.119
, pp. 4541-4553
-
-
Martín-Villar, E.1
-
24
-
-
0038024241
-
Multifunctional kinases in cell behaviour
-
Riento, K., Ridley, A.J. Rocks: multifunctional kinases in cell behaviour. Nat. Rev. Mol. Cell Biol. 4, 446-456 (2003).
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
25
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
Calvo, F. et al. Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat. Cell Biol. 15, 637-646 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 637-646
-
-
Calvo, F.1
-
26
-
-
33645758275
-
Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
-
Wicki, A. et al. Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9, 261-272 (2006).
-
(2006)
Cancer Cell
, vol.9
, pp. 261-272
-
-
Wicki, A.1
-
27
-
-
77949826033
-
Organizing the cell cortex: The role of ERM proteins
-
Fehon, R.G., McClatchey, A.I., Bretscher, A. Organizing the cell cortex: the role of ERM proteins. Nat. Rev. Mol. Cell Biol. 11, 1-12 (2010).
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 1-12
-
-
Fehon, R.G.1
McClatchey, A.I.2
Bretscher, A.3
-
28
-
-
33748328139
-
The matrix reorganized: Extracellular matrix remodeling and integrin signaling
-
Larsen, M., Artym, V.V., Green, J.A., Yamada, K.M. The matrix reorganized: extracellular matrix remodeling and integrin signaling. Curr. Opin. Cell Biol. 18, 463-471 (2006).
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 463-471
-
-
Larsen, M.1
Artym, V.V.2
Green, J.A.3
Yamada, K.M.4
-
29
-
-
84878209722
-
Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity
-
Chai, Q. et al. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity 38, 1013-1024 (2013).
-
(2013)
Immunity
, vol.38
, pp. 1013-1024
-
-
Chai, Q.1
-
30
-
-
80054918372
-
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes
-
Lukacs-Kornek, V. et al. Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes. Nat. Immunol. 12, 1096-1104 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1096-1104
-
-
Lukacs-Kornek, V.1
-
31
-
-
81055124813
-
Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide
-
Siegert, S. et al. Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide. PLoS ONE 6, e27618 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. 27618
-
-
Siegert, S.1
-
32
-
-
81055145081
-
Regulation of T cell priming by lymphoid stroma
-
Khan, O. et al. Regulation of T cell priming by lymphoid stroma. PLoS ONE 6, e26138 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. 26138
-
-
Khan, O.1
-
33
-
-
33746924370
-
Regulation of lymph node vascular growth by dendritic cells
-
Webster, B. et al. Regulation of lymph node vascular growth by dendritic cells. J. Exp. Med. 203, 1903-1913 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1903-1913
-
-
Webster, B.1
-
34
-
-
84919848646
-
Dendritic cells control lymph node expansion via modulation of fibroblastic reticular network tension through CLEC-2/Podoplanin interactions
-
Acton, S.E. et al. Dendritic cells control lymph node expansion via modulation of fibroblastic reticular network tension through CLEC-2/Podoplanin interactions. Nature 514, 498-502 (2014).
-
(2014)
Nature
, vol.514
, pp. 498-502
-
-
Acton, S.E.1
-
35
-
-
84922014960
-
B cell homeostasis and follicle confines are governed by fibroblastic reticular cells
-
Cremasco, V. et al. B cell homeostasis and follicle confines are governed by fibroblastic reticular cells. Nat. Immunol. 15, 973-981 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 973-981
-
-
Cremasco, V.1
-
37
-
-
78650452381
-
Podoplanin associates with CD44 to promote directional cell migration
-
Martín-Villar, E. et al. Podoplanin associates with CD44 to promote directional cell migration. Mol. Biol. Cell 21, 4387-4399 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 4387-4399
-
-
Martín-Villar, E.1
-
38
-
-
67349234088
-
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions
-
Cueni, L.N., Detmar, M. Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions. Exp. Cell Res. 315, 1715-1723 (2009).
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 1715-1723
-
-
Cueni, L.N.1
Detmar, M.2
-
39
-
-
52649170765
-
Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis
-
Nakazawa, Y. et al. Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis. Blood 112, 1730-1739 (2008).
-
(2008)
Blood
, vol.112
, pp. 1730-1739
-
-
Nakazawa, Y.1
-
40
-
-
79955925370
-
The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition
-
Fernández-Munõz, B. et al. The transmembrane domain of podoplanin is required for its association with lipid rafts and the induction of epithelial-mesenchymal transition. Int. J. Biochem. Cell Biol. 43, 886-896 (2011).
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 886-896
-
-
Fernández-Munõz, B.1
-
41
-
-
84878262982
-
Transforming growth factor-b1 (TGF-b1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts
-
Midgley, A.C. et al. Transforming growth factor-b1 (TGF-b1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts. J. Biol. Chem. 288, 14824-14838 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 14824-14838
-
-
Midgley, A.C.1
-
42
-
-
84876947514
-
Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility
-
Krishnan, H. et al. Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility. J. Biol. Chem. 288, 12215-12221 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 12215-12221
-
-
Krishnan, H.1
-
43
-
-
56149111087
-
T1/podoplanin is essential for capillary morphogenesis in lymphatic endothelial cells
-
Navarro, A., Perez, R.E., Rezaiekhaligh, M., Mabry, S.M., Ekekezie, I.I. T1/podoplanin is essential for capillary morphogenesis in lymphatic endothelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 295, L543-L551 (2008).
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.295
, pp. L543-L551
-
-
Navarro, A.1
Perez, R.E.2
Rezaiekhaligh, M.3
Mabry, S.M.4
Ekekezie, I.I.5
-
44
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek, M.J. et al. Tensional homeostasis and the malignant phenotype. Cancer Cell 8, 241-254 (2005).
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
-
45
-
-
70349292059
-
Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening
-
Klein, E.A. et al. Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening. Curr. Biol. 19, 1511-1518 (2009).
-
(2009)
Curr. Biol.
, vol.19
, pp. 1511-1518
-
-
Klein, E.A.1
-
46
-
-
3543023861
-
Focal dhesion kinase Is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type i collagen matrices via a b1 integrin viability signaling pathway
-
Xia, H., Nho, R.S., Kahm, J., Kleidon, J., Henke, C.A. Focal dhesion kinase Is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a b1 integrin viability signaling pathway. J. Biol. Chem. 279, 33024-33034 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33024-33034
-
-
Xia, H.1
Nho, R.S.2
Kahm, J.3
Kleidon, J.4
Henke, C.A.5
-
47
-
-
84891940082
-
Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes
-
Yang, C.Y. et al. Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes. Proc. Natl. Acad. Sci. USA 111, E109-E118 (2014).
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E109-E118
-
-
Yang, C.Y.1
-
48
-
-
66949131422
-
Inflammation recapitulates the ontogeny of lymphoid stromal cells
-
Peduto, L. et al. Inflammation recapitulates the ontogeny of lymphoid stromal cells. J. Immunol. 182, 5789-5799 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 5789-5799
-
-
Peduto, L.1
-
49
-
-
84859859009
-
Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells
-
Fletcher, A.L. et al. Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells. Front. Immunol. 2, 35-50 (2011).
-
(2011)
Front. Immunol.
, vol.2
, pp. 35-50
-
-
Fletcher, A.L.1
-
50
-
-
33847710201
-
CellProfiler™: Free, versatile software for automated biological image analysis
-
Lamprecht, M., Sabatini, D., Carpenter, A. CellProfiler™: free, versatile software for automated biological image analysis. Biotechniques 42, 71-75 (2007).
-
(2007)
Biotechniques
, vol.42
, pp. 71-75
-
-
Lamprecht, M.1
Sabatini, D.2
Carpenter, A.3
|