The malignancy suppression role of miR-23a by targeting the BCR/ABL oncogene in chromic myeloid leukemia

Cancer Gene Therapy

Volumn 21, Issue 9, 2014, Pages 397-404

  Xishan, Z ^a   Xianjun, L ^b   Ziying, L ^a   Guangxin, C ^b   Gang, L ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b WEIFANG PEOPLE'S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BCR ABL PROTEIN; LIPOFECTAMINE; MICRORNA; MICRORNA 23A; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; AZACITIDINE; GELATINASE B; MIRN23 MICRORNA, HUMAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CHRONIC MYELOID LEUKEMIA; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; K562 CELL LINE; LEUKEMIA REMISSION; LUNG CANCER CELL LINE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; UPREGULATION; WESTERN BLOTTING; 3' UNTRANSLATED REGION; BONE MARROW; BONE MARROW CELL; CELL AGING; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; YOUNG ADULT;

3' UNTRANSLATED REGIONS; ADOLESCENT; ADULT; AGED; AZACITIDINE; BONE MARROW; BONE MARROW CELLS; CELL AGING; CELL LINE, TUMOR; FEMALE; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MATRIX METALLOPROTEINASE 9; MICRORNAS; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; YOUNG ADULT;

EID: 84926981532     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2014.44     Document Type: Article

References (41)

1. Teichler S, Illmer T, Roemhild J, Ovcharenko D, Stiewe T, Neubauer A. Micro-RNA29a regulates the expression of the nuclear oncogene Ski. Blood 2011; 118: 1899-1902.
2. Krichevsky AM, King KS, Donahue CP, Khrapko K, Kosik KS. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 2003; 9: 1274-1281.
3. Jørgensen HG, Copland M, Allan EK, Jiang X, Eaves A, Eaves C. Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocytecolony stimulating factor in vitro promotes their elimination by imatinib mesylate. Clin Cancer Res 2006; 12: 626-633.
4. Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H et al. Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (auto-)catalytic activation and resistance to inhibition by TIMP-1. Biochem J 2007; 405: 547-558.
5. Yu Q, Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-? and promotes tumor invasion and angiogenesis. Genes Dev 2000; 14: 163-176.
6. Fridman R, Toth M, Chvyrkova I, Meroueh S, Mobashery S. Cell surface association of matrix metalloproteinase-9 (gelatinase B). Cancer Metast Rev 2003; 22: 153-166.
7. Stefanidakis M, Koivunen E. Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression. Blood 2006; 108: 1441-1450.
8. Xishan Z, Xinna Z, Baoxin H, Jun R. Impaired immunomodulatory function of chronic myeloid leukemia cancer stem cells and the possible mechanism involved in it. Cancer Immunol Immunother 2013; 62: 689-703.
9. Redondo-Muñoz J, Escobar-Díaz E, Samaniego R. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood 2006; 108: 3143-3151.
10. Zhu X, Lin Z, Du J, Zhou X, Yang L, Liu G. Studies on microRNAs that are correlated with the cancer stem cells in chronic myeloid leukemia. Mol Cell Biochem 2014; 390: 75-84.
11. Janowska-Wieczorek A, Majka M, Marquez-Curtis L, Wertheim JA, Turner AR, Ratajczak MZ. Bcr-Abl-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in Matrigel implants. Leukemia 2002; 16: 1160-1166.
12. Chen Z, Chen L, Dai H, Wang P, Gao S, Wang K. MiR-301a promotes pancreatic cancer cell proliferation by directly inhibiting bim expression. J Cell Biochem 2012; 113: 3229-3235.
13. Lu Z, Li Y, Takwi A, Li B, Zhang J, Conklin DJ et al. miR-301a as an NF-kappaB activator in pancreatic cancer cells. EMBO J 2011; 30: 57-67.
14. Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clin Cancer Res 2006; 12: 1828-1838.
15. Kaneta Y, Kagami Y, Tsunoda T, Ohno R, Nakamura Y, Katagiri T. Genome-wide analysis of gene-expression profiles in chronic myeloid leukemia cells using a cDNA microarray. Int J Oncol 2003; 23: 681-691.
16. MacLellan SA, MacAulay C, Lam S, Garnis C. Pre-profiling factors influencing serum microRNA levels. BMC Clin Pathol 2014; 21: 14-27.
17. Wang X, Tian L, Wu H, Jiang X, Du L, Zhang H et al. Expression of miRNA-130a in nonsmall cell lung cancer. Am J Med Sci 2010; 340: 385-388.
18. Chen Y, Gorski DH. Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5. Blood 2008; 111: 1217-1226.
19. Suresh S, McCallum L, Lu W, Lazar N, Perbal B, Irvine AE. microRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML. J Cell Commun Signal 2011; 5: 183-191.
20. Zhou P, Jiang W, Wu L, Chang R, Wu K, Wang Z. miR-301a is a candidate oncogene that targets the homeobox gene Gax in human hepatocellular carcinoma. Dig Dis Sci 2012; 57: 1171-1180.
21. Shi W, Gerster K, Alajez NM, Tsang J, Waldron L, Pintilie M et al. MicroRNA-301 mediates proliferation and invasion in human breast cancer. Cancer Res 2011; 71: 2926-2937.
22. Kovaleva V, Mora R, Park YJ, Plass C, Chiramel AI, Bartenschlager R et al. MiRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells. Cancer Res 2012; 72: 1763-1772.
23. Patel N, Tahara SM, Malik P, Kalra VK. Involvement of miR-30c and miR-301a in immediate induction of plasminogen activator inhibitor-1 by placental growth factor in human pulmonary endothelial cells. Biochem J 2011; 434: 473-482.
24. Baskerville S, Bartel DP. Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 2005; 11: 241-247.
25. Pouladi N, Kouhsari SM, Feizi MH, Gavgani RR, Azarfam P. Overlapping region of p53/Wrap53 transcripts: mutational analysis and sequence similarity with microRNA-4732-5p. Asian Pac J Cancer Prev 2013; 14: 3503-3507.
26. Wang L, Li B, Li L, Wang T. microRNA-497 suppresses proliferation and induces apoptosis in prostate cancer cells. Asian Pac J Cancer Prev 2013; 14: 3499-3502.
27. Xing HJ, Li YJ, Ma QM, Wang AM, Wang JL, Sun M et al. Identification of micro-RNAs present in congenital heart disease associated copy number variants. Eur Rev Med Pharmacol Sci 2013; 172114-2120.
28. Li X, Zhang X, Wang T, Sun C, Jin T, Yan H et al. Regulation by bisoprolol for cardiac microRNA expression in a rat volume-overload heart failure model. J Nanosci Nanotechnol 2013; 13: 5267-5275.
29. Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 2005; 102: 13944-13949.
30. Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 2005; 33: 1290-1297.
31. Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A et al. microRNAresponsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet 2004; 36: 1079-1083.
32. Felli N, Fontana L, Pelosi E, Botta R, Bonci D, Facchiano F et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci USA 2005; 102: 18081-18086.
33. Karaayvaz M, Zhai H, Ju J. miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. Cell Death Dis 2013; 4: e659.
34. Zhang J, Zhang D, Wu GQ, Feng ZY, Zhu SM. Propofol inhibits the adhesion of hepatocellular carcinoma cells by upregulating microRNA-199a and downregulating MMP-9 expression. Hepatobiliary Pancreat Dis Int 2013; 12: 305-309.
35. Ma D, Tao X, Gao F, Fan C, Wu D. MiR-224 functions as an onco-miRNA in hepatocellular carcinoma cells by activating AKT signaling. Oncol Lett 2012; 4: 483-488.
36. Goedeke L, Vales-Lara FM, Fenstermaker M, Cirera-Salinas D, Chamorro-Jorganes A, Ramírez CM et al. A regulatory role for microRNA 33 in controlling lipid metabolism gene expression. Mol Cell Biol 2013; 332339-2352.
37. Cheng C, Li W, Zhang Z, Yoshimura S, Hao Q, Zhang C et al. MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of Alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10). J Biol Chem 2013; 288: 13748-13761.
38. Kiriakidou M, Nelson PT, Kouranov A, Fitziev P, Bouyioukos C, Mourelatos Z et al. A combined computational experimental approach predicts human microRNA targets. Genes Dev 2004; 18: 1165-1178.
39. Krek A. Combinatorial microRNA target predictions. Nature Genet 2005; 37: 495-500.
40. Grun D, Wang Y, Langenberger D, Gunsalus KC, Rajewsky N. MicroRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol 2005; 1: e13.
41. Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P et al. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol 2004; 5: R68.