Intravital and whole-organ imaging reveals capture of melanoma-derived antigen by lymph node subcapsular macrophages leading to widespread deposition on follicular dendritic cells

Frontiers in Immunology

Volumn 6, Issue MAR, 2015, Pages

  Moalli, Federica ^a   Proulx, Steven T ^b   Schwendener, Reto ^c   Detmar, Michael ^b   Schlapbach, Christoph ^d   Stein, Jens V ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

Follicular dendritic cells; Intravital two photon imaging; Tumor derived antigen deposition; Tumor draining lymph node; Whole organ imaging

Indexed keywords

TUMOR ANTIGEN;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; FOLLICULAR DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE MICROSCOPY; INTRAVITAL TWO PHOTON IMAGING; LYMPH NODE METASTASIS; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; QUANTITATIVE ASSAY; TUMOR IMMUNITY; WHOLE ORGAN IMAGING;

EID: 84926674094     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00114     Document Type: Article

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