Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck

Nature Communications

Volumn 6, Issue , 2015, Pages

  Zaraket, Hassan ^a,b   Baranovich, Tatiana ^a   Kaplan, Bryan S ^a   Carter, Robert ^a   Song, Min Suk ^a,h   Paulson, James C ^c   Rehg, Jerold E ^a   Bahl, Justin ^d   Crumpton, Jeri C ^a   Seiler, Jon ^a   Edmonson, Michael ^a   Wu, Gang ^a   Karlsson, Erik ^a   Fabrizio, Thomas ^a   Zhu, Huachen ^e   Guan, Yi ^e   Husain, Matloob ^f   Schultz Cherry, Stacey ^a   Krauss, Scott ^a   McBride, Ryan ^c   Webster, Robert G ^a   Govorkova, Elena A ^a   Zhang, Jinghui ^a   Russell, Charles J ^a,g   Webby, Richard J ^a,g   more..

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^e Shantou University Medical College   (China)

^f UNIVERSITY OF OTAGO   (New Zealand)

^g UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

^h Chungbuk National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; AVIAN INFLUENZA; DISEASE TRANSMISSION; ENZYME ACTIVITY; EPIDEMIC; FITNESS; MAMMAL; MUTATION; POPULATION BOTTLENECK; POULTRY; PUBLIC HEALTH; RISK ASSESSMENT; VIRUS;

ADAPTATION; ADULT; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHICKEN; CONTROLLED STUDY; FERRET; GENE REPLICATION; GENETIC ANALYSIS; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLUENZA VIRUS A H7N9; MALE; MDCK CELL LINE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; RECEPTOR BINDING; RISK ASSESSMENT; SEQUENCE ANALYSIS; VIRUS INFECTIVITY; VIRUS RECOMBINANT; VIRUS SHEDDING; VIRUS TRANSMISSION; VIRUS VIRULENCE; YOUNG ADULT; ANIMAL; ASYMPTOMATIC INFECTION; AVIAN INFLUENZA; CHLOROCEBUS AETHIOPS; DOG; GENETIC VARIATION; GENETICS; HEK293 CELL LINE; INFLUENZA; INFLUENZA A VIRUS (H7N9); MULTIPLEX POLYMERASE CHAIN REACTION; MUTATION; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION; VERO CELL LINE; VIROLOGY;

AVES; GALLUS GALLUS; INFLUENZA A VIRUS; MAMMALIA; MUSTELA; ORTHOMYXOVIRIDAE;

CORE PROTEIN; INFLUENZA VIRUS POLYMERASE BASIC PROTEIN 1; NA PROTEIN, INFLUENZA A VIRUS; NP PROTEIN, INFLUENZA A VIRUS; RNA BINDING PROTEIN; SIALIDASE; VIRAL PROTEIN; VIRUS RNA;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ASYMPTOMATIC INFECTIONS; CERCOPITHECUS AETHIOPS; CHICKENS; DOGS; FERRETS; GENETIC VARIATION; HEK293 CELLS; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA IN BIRDS; INFLUENZA, HUMAN; MADIN DARBY CANINE KIDNEY CELLS; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATION; NEURAMINIDASE; ORTHOMYXOVIRIDAE INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; RNA-BINDING PROTEINS; VERO CELLS; VIRAL CORE PROTEINS; VIRAL PROTEINS;

EID: 84926647098     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7553     Document Type: Article

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