The polymerase acidic protein gene of influenza A virus contributes to pathogenicity in a mouse model

Journal of Virology

Volumn 83, Issue 23, 2009, Pages 12325-12335

  Song, Min Suk ^a   Pascua, Philippe Noriel Q ^a   Lee, Jun Han ^a   Baek, Yun Hee ^a   Lee, Ok Jun ^a   Kim, Chul Joong ^b   Kim, Hyunggee ^c   Webby, Richard J ^d   Webster, Robert G ^d   Choi, Young Ki ^a  

^a Chungbuk National University College of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

^c Korea University   (South Korea)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PROTEIN; DNA DIRECTED DNA POLYMERASE; ISOLEUCINE; POLYMERASE ACIDIC PROTEIN; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA; CHICKEN; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HOST RANGE; IMMUNOHISTOCHEMISTRY; INFLUENZA VIRUS A; INFLUENZA VIRUS A H5N2; MIGRATORY SPECIES; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRAIN DIFFERENCE; TISSUE CULTURE; VIROGENESIS; VIRUS GENE; VIRUS ISOLATION; VIRUS MUTATION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ADAPTATION, BIOLOGICAL; ANIMALS; BIRD DISEASES; BIRDS; CELL LINE; GENETIC ENGINEERING; INFLUENZA A VIRUS, H5N2 SUBTYPE; INFLUENZA IN BIRDS; KOREA; LETHAL DOSE 50; LUNG; MICE; MICE, INBRED BALB C; MUTATION, MISSENSE; ORTHOMYXOVIRIDAE INFECTIONS; RNA REPLICASE; SERIAL PASSAGE; SURVIVAL ANALYSIS; VIRAL PROTEINS; VIRULENCE FACTORS;

AVES; AVIAN INFLUENZA VIRUS; GALLUS GALLUS; INFLUENZA A VIRUS; MAMMALIA; MUS;

EID: 70450170087     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01373-09     Document Type: Article

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