Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren's syndrome

Arthritis Research and Therapy

Volumn 17, Issue 1, 2015, Pages

  Bian, Fang ^a   Barbosa, Flavia L ^a   Corrales, Rosa M ^a   Pelegrino, Flavia ^a   Volpe, Eugene A ^a   Pflugfelder, Stephen C ^a   de Paiva, Cintia S ^a  

^a CULLEN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; IL2RA PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASSAY; CELL INFILTRATION; CELL LYSATE; CONTROLLED STUDY; DACRYOCYSTITIS; ENZYME ACTIVITY; EXPERIMENTAL MODEL; FLOW CYTOMETRY; HELPER CELL; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; LACRIMAL FLUID; LACRIMAL GLAND; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; SJOEGREN SYNDROME; T LYMPHOCYTE; ANIMAL; CHEMISTRY; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETICS; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LACRIMAL APPARATUS; MALE; METABOLISM; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INTERFERON-GAMMA; INTERLEUKIN-13; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LACRIMAL APPARATUS; MALE; MICE; MICE, KNOCKOUT; SJOGREN'S SYNDROME; TEARS;

EID: 84926638946     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0582-9     Document Type: Article

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