-
2
-
-
0001849254
-
Aqueous tear deficiency in Sjögren's syndrome: Possible causes and potential treatment
-
Pleyer U, Hartmenn C, eds. Buren, Netherlands: Aeolus Press
-
Sullivan DA, Wickham LA, Krenzer KL, Rocha EM, Toda I. Aqueous tear deficiency in Sjögren's syndrome: possible causes and potential treatment. In: Pleyer U, Hartmenn C, eds. Oculodermal Diseases. Buren, Netherlands: Aeolus Press; 1997:95-152.
-
(1997)
Oculodermal Diseases
, pp. 95-152
-
-
Sullivan, D.A.1
Wickham, L.A.2
Krenzer, K.L.3
Rocha, E.M.4
Toda, I.5
-
3
-
-
31744441241
-
Effect of inflammation on lacrimal gland function
-
DOI 10.1016/j.exer.2005.10.018, PII S0014483505003465
-
Zoukhri D. Effect of inflammation on lacrimal gland function. Exp Eye Res. 2006;82:885-898. (Pubitemid 43173444)
-
(2006)
Experimental Eye Research
, vol.82
, Issue.5
, pp. 885-898
-
-
Zoukhri, D.1
-
4
-
-
0036241336
-
Role, of proinflammatory cytokines in the impaired lacrimation associated with autoimmune xerophthalmia
-
Zoukhri D, Hodges RR, Byon D, Kublin CL. Role of proinflammatory cytokines in the impaired lacrimation associated with autoimmune xerophthalmia. Invest Ophthalmol Vis Sci. 2002;43:1429-1436. (Pubitemid 34462641)
-
(2002)
Investigative Ophthalmology and Visual Science
, vol.43
, Issue.5
, pp. 1429-1436
-
-
Zoukhri, D.1
Hodges, R.R.2
Byon, D.3
Kublin, C.L.4
-
5
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996;87:2095-2174.
-
(1996)
Blood
, vol.87
, pp. 2095-2174
-
-
Dinarello, C.A.1
-
6
-
-
0033874108
-
Proinflammatory cytokines
-
Dinarello CA. Proinflammatory cytokines. Chest. 2000;118:503-508.
-
(2000)
Chest
, vol.118
, pp. 503-508
-
-
Dinarello, C.A.1
-
7
-
-
0031973493
-
Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells
-
Schumann RR, Belka C, Reuter D, et al. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells. Blood. 1998;91:577-584. (Pubitemid 28053381)
-
(1998)
Blood
, vol.91
, Issue.2
, pp. 577-584
-
-
Schumann, R.R.1
Belka, C.2
Reuter, D.3
Lamping, N.4
Kirschning, C.J.5
Weber, J.R.6
Pfeil, D.7
-
8
-
-
0036671894
-
The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
DOI 10.1016/S1097-2765(02)00599-3
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10:417-426. (Pubitemid 35007355)
-
(2002)
Molecular Cell
, vol.10
, Issue.2
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
9
-
-
7944231451
-
ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules
-
DOI 10.1111/j.1365-2443.2004.00789.x
-
Yamamoto M, Yaginuma K, Tsutsui H, et al. ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules. Genes Cells. 2004;9:1055-1067. (Pubitemid 39467978)
-
(2004)
Genes to Cells
, vol.9
, Issue.11
, pp. 1055-1067
-
-
Yamamoto, M.1
Yaginuma, K.2
Tsutsui, H.3
Sagara, J.4
Guan, X.5
Seki, E.6
Yasuda, K.7
Yamamoto, M.8
Akira, S.9
Nakanishi, K.10
Noda, T.11
Taniguchi, S.12
-
10
-
-
0033866952
-
Leakage of aquaporin 5 in the tear of dacryoadenitis mice
-
Hirai S-I, Ishida N, Watanabe K, Mita S. Leakage of aquaporin 5 in the tear of dacryoadenitis mice. Invest Ophthalmol Vis Sci. 2000;41:2432-2437. (Pubitemid 30624366)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.9
, pp. 2432-2437
-
-
Hirai, S.-I.1
Ishida, N.2
Watanabe, K.3
Mita, S.4
-
11
-
-
0344196965
-
The interleukin 1 receptor: Ligand interactions and signal transduction
-
DOI 10.1016/S1359-6101(98)00018-5, PII S1359610198000185
-
Auron PE. The interleukin 1 receptor: ligand interactions and signal transduction. Cytokine Growth Factor Rev. 1998;9:221-237. (Pubitemid 29019708)
-
(1998)
Cytokine and Growth Factor Reviews
, vol.9
, Issue.3-4
, pp. 221-237
-
-
Auron, P.E.1
-
12
-
-
0034075754
-
The IL-1 receptor/toll-like receptor superfamily: Crucial receptors for inflammation and host defense
-
O'Neill LA, Dinarello CA. The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunol Today. 2000;21:206-209.
-
(2000)
Immunol Today
, vol.21
, pp. 206-209
-
-
O'Neill, L.A.1
Dinarello, C.A.2
-
13
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
DOI 10.1016/S0962-8924(01)02064-5, PII S0962892401020645
-
Baud V, Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 2001;11:372-377. (Pubitemid 32900529)
-
(2001)
Trends in Cell Biology
, vol.11
, Issue.9
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
14
-
-
0033231020
-
From receptors to stress-activated MAP kinases
-
Ichijo H. From receptors to stress-activated MAP kinases. Oncogene. 1999;18:6087-6093.
-
(1999)
Oncogene
, vol.18
, pp. 6087-6093
-
-
Ichijo, H.1
-
15
-
-
0030765077
-
Stress-activated protein kinases: Activation, regulation and function
-
DOI 10.1016/S0898-6568(97)00042-9, PII S0898656897000429
-
Paul A, Wilson S, Belham CM, et al. Stress-activated protein kinases: activation, regulation and function. Cell Signal. 1997;9:403-410. (Pubitemid 27417165)
-
(1997)
Cellular Signalling
, vol.9
, Issue.6
, pp. 403-410
-
-
Paul, A.1
Wilson, S.2
Belham, C.M.3
Robinson, C.J.M.4
Scott, P.H.5
Gould, G.W.6
Plevin, R.7
-
16
-
-
33644848143
-
C-Jun NH2-terminal kinase mediates interleukin-1β-induced inhibition of lacrimal gland secretion
-
Zoukhri D, Macari E, Choi SH, Kublin CL. c-Jun NH2-terminal kinase mediates interleukin-1β-induced inhibition of lacrimal gland secretion. J Neurochem. 2006;96:126-135.
-
(2006)
J Neurochem
, vol.96
, pp. 126-135
-
-
Zoukhri, D.1
Macari, E.2
Choi, S.H.3
Kublin, C.L.4
-
17
-
-
0035068208
-
Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome
-
Zoukhri D, Kublin CL. Impaired neurotransmitter release from lacrimal and salivary gland nerves of a murine model of Sjogren's syndrome. Invest Ophthalmol Vis Sci. 2001;42:925-932. (Pubitemid 32289786)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.5
, pp. 925-932
-
-
Zoukhri, D.1
Kublin, C.L.2
-
19
-
-
34247110895
-
A single injection of interleukin-1 induces reversible aqueous-tear deficiency, lacrimal gland inflammation, and acinar and ductal cell proliferation
-
Zoukhri D, Macari E, Kublin CL. A single injection of interleukin-1 induces reversible aqueous-tear deficiency, lacrimal gland inflammation, and acinar and ductal cell proliferation. Exp Eye Res. 2007;84:894-904.
-
(2007)
Exp Eye Res
, vol.84
, pp. 894-904
-
-
Zoukhri, D.1
Macari, E.2
Kublin, C.L.3
-
20
-
-
0031004174
-
Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
DOI 10.1038/386619a0
-
Ghayur T, Banerjee S, Hugunin M, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature. 1997;386:619-623. (Pubitemid 27175429)
-
(1997)
Nature
, vol.386
, Issue.6625
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
Quintal, L.7
Sekut, L.8
Talanian, R.9
Paskind, M.10
Wong, W.11
Kamen, R.12
Tracey, D.13
Allen, H.14
-
21
-
-
0036141077
-
Therapeutic application of caspase 1/interleukin-1β-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis
-
DOI 10.1097/00000658-200201000-00009
-
Paszkowski AS, Rau B, Mayer JM, Moller P, Beger HG. Therapeutic application of caspase 1/interleukin-1β-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis. Ann Surg. 2002;235:68-76. (Pubitemid 34062401)
-
(2002)
Annals of Surgery
, vol.235
, Issue.1
, pp. 68-76
-
-
Paszkowski, A.S.1
Rau, B.2
Mayer, J.M.3
Moller, P.4
Beger, H.G.5
-
22
-
-
0033238104
-
Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: Localization and role in the maturation of interleukin-1beta and interleukin-18
-
DOI 10.1002/1529-0131(199908)42:8<1577::AID-ANR3>3.0.CO;2-Z
-
Saha N, Moldovan F, Tardif G, Pelletier JP, Cloutier JM, Martel- Pelletier J. Interleukin-1beta-converting enzyme/caspase-1 in human osteoarthritic tissues: localization and role in the maturation of interleukin-1beta and interleukin-18. Arthritis Rheum. 1999;42:1577-1587. (Pubitemid 30263623)
-
(1999)
Arthritis and Rheumatism
, vol.42
, Issue.8
, pp. 1577-1587
-
-
Saha, N.1
Moldovan, F.2
Tardif, G.3
Pelletier, J.-P.4
Cloutier, J.-M.5
Martel-Pelletier, J.6
-
23
-
-
0034713932
-
Lipopolysaccharlde inhibits long term potentiation in the rat dentate gyrus by activating caspase-1
-
DOI 10.1074/jbc.M002226200
-
Vereker E, Campbell V, Roche E, McEntee E, Lynch MA. Lipopolysaccharide inhibits long term potentiation in the rat dentate gyrus by activating caspase-1. J Biol Chem. 2000;275:26252-26258. (Pubitemid 30676674)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.34
, pp. 26252-26258
-
-
Vereker, E.1
Campbell, V.2
Roche, E.3
McEntee, E.4
Lynch, M.A.5
-
24
-
-
0028984948
-
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
-
Li P, Allen H, Banerjee S, et al. Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock. Cell. 1995;80:401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
-
25
-
-
0031044777
-
Characterization of mice deficient in interleukin-1β converting enzyme
-
DOI 10.1002/(SICI)1097-4644(199701)64:1<27::AID-JCB5>3.0.CO;2-1
-
Li P, Allen H, Banerjee S, Seshadri T. Characterization of mice deficient in interleukin-1β-converting enzyme. J Cell Biochem. 1997;64:27-32. (Pubitemid 27081792)
-
(1997)
Journal of Cellular Biochemistry
, vol.64
, Issue.1
, pp. 27-32
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Seshadri, T.4
-
26
-
-
0027212297
-
Modalities for reducing interleukin 1 activity in disease
-
DOI 10.1016/0167-5699(93)90042-J
-
Dinarello CA. Modalities for reducing interleukin 1 activity in disease. Immunol Today. 1993;14:260-264. (Pubitemid 23186987)
-
(1993)
Immunology Today
, vol.14
, Issue.6
, pp. 260-264
-
-
Dinarello, C.A.1
-
27
-
-
0031044283
-
In vitro and in vivo studies of ICE inhibitors
-
Livingston DJ. In vitro and in vivo studies of ICE inhibitors. J Cell Biochem. 1997;64:19-26.
-
(1997)
J Cell Biochem
, vol.64
, pp. 19-26
-
-
Livingston, D.J.1
-
28
-
-
0034929774
-
ICE/Caspase-1 inhibitors as novel anti-inflammatory drugs
-
DOI 10.1517/13543784.10.7.1207
-
Randle JC, Harding MW, Ku G, Schonharting M, Kurrle R. ICE/ caspase-1 inhibitors as novel anti-inflammatory drugs. Expert Opin Investig Drugs. 2001;10:1207-1209. (Pubitemid 32633564)
-
(2001)
Expert Opinion on Investigational Drugs
, vol.10
, Issue.7
, pp. 1207-1209
-
-
Randle, J.C.R.1
Harding, M.W.2
Ku, G.3
Schonharting, M.4
Kurrle, R.5
-
29
-
-
23444439667
-
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
-
Stack JH, Beaumont K, Larsen PD, et al. IL-converting enzyme/ caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoin- flammatory syndrome patients. J Immunol. 2005;175:2630-2634. (Pubitemid 41113877)
-
(2005)
Journal of Immunology
, vol.175
, Issue.4
, pp. 2630-2634
-
-
Stack, J.H.1
Beaumont, K.2
Larsen, P.D.3
Straley, K.S.4
Henkel, G.W.5
Randle, J.C.R.6
Hoffman, H.M.7
-
30
-
-
34247219224
-
(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3, 3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo- Tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18
-
DOI 10.1124/jpet.106.111344
-
Wannamaker W, Davies R, Namchuk M, et al. (S)-1-((S)-2-{[1-(4- amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)- pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydrofuran- 3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent antiinflammatory activities by inhibiting the release of IL-1beta and IL-18. J Pharmacol Exp Ther. 2007;321:509-516. (Pubitemid 46624508)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 509-516
-
-
Wannamaker, W.1
Davies, R.2
Namchuk, M.3
Pollard, J.4
Ford, P.5
Ku, G.6
Decker, C.7
Charifson, P.8
Weber, P.9
Germann, U.A.10
Kuida, K.11
Randle, J.C.R.12
-
31
-
-
9444263191
-
Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface
-
DOI 10.1167/iovs.03-1145
-
Luo L, Li DQ, Doshi A, Farley W, Corrales RM, Pflugfelder SC. Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface. Invest Ophthalmol Vis Sci. 2004;45:4293-4301. (Pubitemid 39564653)
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, Issue.12
, pp. 4293-4301
-
-
Luo, L.1
Li, D.-Q.2
Doshi, A.3
Farley, W.4
Corrales, R.M.5
Pflugfelder, S.C.6
-
32
-
-
84949117022
-
Stress-activated protein kinase signaling pathways in dry eye and ocular surface disease
-
Pflugfelder SC, de Paiva CS, Tong L, Luo L, Stern ME, Li DQ. Stress-activated protein kinase signaling pathways in dry eye and ocular surface disease. Ocul Surf. 2005;3:S154-S157.
-
(2005)
Ocul Surf
, vol.3
-
-
Pflugfelder, S.C.1
De Paiva, C.S.2
Tong, L.3
Luo, L.4
Stern, M.E.5
Li, D.Q.6
-
33
-
-
31044455375
-
JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells
-
DOI 10.1016/j.exer.2005.08.019, PII S0014483505002654
-
Li DQ, Luo L, Chen Z, Kim HS, Song XJ, Pflugfelder SC. JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res. 2006;82:588-596. (Pubitemid 43122089)
-
(2006)
Experimental Eye Research
, vol.82
, Issue.4
, pp. 588-596
-
-
Li, D.-Q.1
Luo, L.2
Chen, Z.3
Kim, H.-S.4
Song, X.J.5
Pflugfelder, S.C.6
-
34
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne A, O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE. 2003;2003:re3.
-
(2003)
Sci STKE
, vol.2003
-
-
Dunne, A.1
O'Neill, L.A.2
-
35
-
-
31144438009
-
Biological complexity and drug discovery: A practical systems biology approach
-
Berg EL, Kunkel EJ, Hytopoulos E. Biological complexity and drug discovery: a practical systems biology approach. Syst Biol (Stevenage). 2005;152:201-206.
-
(2005)
Syst Biol (Stevenage)
, vol.152
, pp. 201-206
-
-
Berg, E.L.1
Kunkel, E.J.2
Hytopoulos, E.3
|