Differential modulation by IL-17A of cholangitis versus colitis in IL-2Rα deleted mice

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Yang, Wei ^a   Yao, Yuan ^a   Yang, Yan Qing ^a   Lu, Fang Ting ^a   Li, Liang ^a   Wang, Yin Hu ^a   Nakajima, Takahiko ^b   Tsuneyama, Koichi ^b   Ridgway, William M ^c   Gershwin, M Eric ^d   Lian, Zhe Xiong ^a,e  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF TOYAMA   (Japan)

^c UNIVERSITY OF CINCINNATI   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHOLANGITIS; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HETEROZYGOSITY; HISTOPATHOLOGY; IMMUNOPATHOLOGY; MOUSE; NATURAL KILLER CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN DEPLETION; QUANTITATIVE ANALYSIS; TH17 CELL; ANIMAL; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CHOLANGITIS; COLITIS; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, KNOCKOUT;

EID: 84926620808     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105351     Document Type: Article

References (32)

1. Hirschfield GM, Gershwin ME (2013) The immunobiology and pathophysiology of primary biliary cirrhosis. Annu Rev Pathol 8: 303-330.
2. Wakabayashi K, Lian ZX, Moritoki Y, Lan RY, Tsuneyama K, et al. (2006) IL-2 receptor alpha(-/-) mice and the development of primary biliary cirrhosis. Hepatology 44: 1240-1249. (Pubitemid 44748374)
3. Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, et al. (1995) Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3: 521-530.
4. Hsu W, Zhang W, Tsuneyama K, Moritoki Y, Ridgway WM, et al. (2009) Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) mice. Hepatology 49: 133-140.
5. Zhang J (2007) Yin and yang interplay of IFN-gamma in inflammation and autoimmune disease. J Clin Invest 117: 871-873.
6. Stark MA, Huo Y, Burcin TL, Morris MA, Olson TS, et al. (2005) Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22: 285-294. (Pubitemid 40387471)
7. Shin HC, Benbernou N, Fekkar H, Esnault S, Guenounou M (1998) Regulation of IL-17, IFN-gamma and IL-10 in human CD8(+) T cells by cyclic AMP-dependent signal transduction pathway. Cytokine 10: 841-850. (Pubitemid 29002736)
8. He D, Wu L, Kim HK, Li H, Elmets CA, et al. (2006) CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 177: 6852-6858. (Pubitemid 44715050)
9. Cupedo T, Crellin NK, Papazian N, Rombouts EJ, Weijer K, et al. (2009) Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells. Nat Immunol 10: 66-74.
10. Langrish CL, McKenzie BS, Wilson NJ, de Waal Malefyt R, Kastelein RA, et al. (2004) IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol Rev 202: 96-105. (Pubitemid 39576907)
11. O'Connor W Jr, Zenewicz LA, Flavell RA (2010) The dual nature of T(H)17 cells: shifting the focus to function. Nat Immunol 11: 471-476.
12. Lee KA, Kang MH, Lee YS, Kim YJ, Kim DH, et al. (2008) A distinct subset of natural killer T cells produces IL-17, contributing to airway infiltration of neutrophils but not to airway hyperreactivity. Cell Immunol 251: 50-55.
13. Elson CO, Cong Y, Weaver CT, Schoeb TR, McClanahan TK, et al. (2007) Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice. Gastroenterology 132: 2359-2370. (Pubitemid 46890867)
14. Lafdil F, Miller AM, Ki SH, Gao B (2010) Th17 cells and their associated cytokines in liver diseases. Cell Mol Immunol 7: 250-254.
15. Lian ZX, Okada T, He XS, Kita H, Liu YJ, et al. (2003) Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations. J Immunol 170: 2323-2330. (Pubitemid 36245618)
16. Ando Y, Yang GX, Tsuda M, Kawata K, Zhang W, et al. (2012) The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II mice. Hepatology 56: 1418-1426.
17. Zhou R, Wei H, Sun R, Tian Z (2007) Recognition of double-stranded RNA by TLR3 induces severe small intestinal injury in mice. J Immunol 178: 4548-4556. (Pubitemid 46492407)
18. Gaffen SL (2009) Structure and signalling in the IL-17 receptor family. Nat Rev Immunol 9: 556-567.
19. Gaffen SL (2009) The role of interleukin-17 in the pathogenesis of rheumatoid arthritis. Curr Rheumatol Rep 11: 365-370.
20. van den Berg WB, Miossec P (2009) IL-17 as a future therapeutic target for rheumatoid arthritis. Nat Rev Rheumatol 5: 549-553.
21. Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, et al. (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201: 233-240. (Pubitemid 40189432)
22. Yi T, Zhao D, Lin CL, Zhang C, Chen Y, et al. (2008) Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease. Blood 112: 2101-2110.
23. Lafdil F, Wang H, Park O, Zhang W, Moritoki Y, et al. (2009) Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production. Gastroenterology 137: 2125-2135 e2121-2122.
24. Lemmers A, Moreno C, Gustot T, Marechal R, Degre D, et al. (2009) The interleukin-17 pathway is involved in human alcoholic liver disease. Hepatology 49: 646-657.
25. Harada K, Shimoda S, Sato Y, Isse K, Ikeda H, et al. (2009) Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis. Clin Exp Immunol 157: 261-270.
26. Zhang JY, Zhang Z, Lin F, Zou ZS, Xu RN, et al. (2010) Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology 51: 81-91.
27. Ge J, Wang K, Meng QH, Qi ZX, Meng FL, et al. (2010) Implication of Th17 and Th1 cells in patients with chronic active hepatitis B. J Clin Immunol 30: 60-67.
28. Lan RY, Salunga TL, Tsuneyama K, Lian ZX, Yang GX, et al. (2009) Hepatic IL-17 responses in human and murine primary biliary cirrhosis. J Autoimmun 32: 43-51.
29. Zhang Z, Zheng M, Bindas J, Schwarzenberger P, Kolls JK (2006) Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis 12: 382-388.
30. Ogawa A, Andoh A, Araki Y, Bamba T, Fujiyama Y (2004) Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice. Clin Immunol 110: 55-62. (Pubitemid 38177420)
31. O'Connor W Jr, Kamanaka M, Booth CJ, Town T, Nakae S, et al. (2009) A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol 10: 603-609.
32. Kamanaka M, Huber S, Zenewicz LA, Gagliani N, Rathinam C, et al. (2011) Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology. J Exp Med 208: 1027-1040.