A round robin approach to the analysis of bisphenol a (BPA) in human blood samples

Environmental Health: A Global Access Science Source

Volumn 13, Issue 1, 2014, Pages

  Vandenberg, Laura N ^a   Gerona, Roy R ^b   Kannan, Kurunthachalam ^c   Taylor, Julia A ^d   Van Breemen, Richard B ^e   Dickenson, Carrie A ^b   Liao, Chunyang ^f   Yuan, Yang ^e   Newbold, Retha R ^g   Padmanabhan, Vasantha ^h   Vom Saal, Frederick S ^d   Woodruff, Tracey J ^b  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^f WADSWORTH CENTER   (United States)

^g NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^h UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Biomonitoring; Contamination; Endocrine disruptor; Linearity; Metabolite; Toxicokinetics

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; GLUCURONIDE; BENZHYDRYL DERIVATIVE; BISPHENOL A GLUCURONIDE; PHENOL DERIVATIVE;

BIOACCUMULATION; BIOMONITORING; BLOOD; ENZYME ACTIVITY; HYDROCARBON; HYDROLYSIS; LABORATORY METHOD; METABOLITE; POLLUTION EXPOSURE; QUANTITATIVE ANALYSIS; SAMPLING;

ANALYTIC METHOD; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTAMINATION; CONTROLLED STUDY; HUMAN; HYDROLYSIS; LABORATORY; LIQUID CHROMATOGRAPHY; METABOLITE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ANIMAL; BLOOD; ENVIRONMENTAL MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; POLLUTANT; RAT;

ANIMALS; BENZHYDRYL COMPOUNDS; BLOOD SPECIMEN COLLECTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; GLUCURONIDES; HUMANS; LABORATORIES; PHENOLS; RATS; TANDEM MASS SPECTROMETRY;

EID: 84926455831     PISSN: None     EISSN: 1476069X     Source Type: Journal    
DOI: 10.1186/1476-069X-13-25     Document Type: Article

References (91)

1. Vandenberg LN, Hauser R, Marcus M, Olea N, Welshons WV: Human exposure to bisphenol A (BPA). Reprod Toxicol 2007,24(2):139-177. 10.1016/j.reprotox.2007.07.010
2. Schecter A, Malik N, Haffner D, Smith S, Harris TR, Paepke O, Birnbaum L: Bisphenol A (BPA) in U.S. food. Environ Sci Technol 2010,44(24):9425-9430. 10.1021/es102785d
3. Welshons WV, Nagel SC, Vom Saal FS: Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 2006, 147:S56-S69. 10.1210/en.2005-1159
4. Biedermann S, Tschudin P, Grob K: Transfer of bisphenol A from thermal printer paper to the skin. Anal Bioanal Chem 2010,398(1):571-576. 10.1007/s00216-010-3936-9
5. Liao C, Kannan K: Widespread occurrence of bisphenol A in paper and paper products: implications for human exposure. Environ Sci Technol 2011,45(21):9372-9379. 10.1021/es202507f
6. Mendum T, Stoler E, VanBenschoten H, Warner JC: Concentration of bisphenol A in thermal paper. Green Chem Lett Rev 2011,4(1):81-86. 10.1080/17518253.2010.502908
7. Loganathan SN, Kannan K: Occurrence of bisphenol A in indoor dust from two locations in the eastern United States and implications for human exposures. Arch Environ Contam Toxicol 2011,61(1):68-73. 10.1007/s00244-010-9634-y
8. Dodson RE, Nishioka M, Standley LJ, Perovich LJ, Brody JG, Rudel RA: Endocrine disruptors and asthma-associated chemicals in consumer products. Environ Health Perspect 2012,120(7):935-943. 10.1289/ehp.1104052
9. Geens T, Aerts D, Berthot C, Bourguignon JP, Goeyens L, Lecomte P, Maghuin-Rogister G, Pironnet AM, Pussemier L, Scippo ML, Van Loco J, Covaci A: A review of dietary and non-dietary exposure to bisphenol-A. Food Chem Toxicol 2012,50(10):3725-3740. 10.1016/j.fct.2012.07.059
10. Geens T, Goeyens L, Covaci A: Are potential sources for human exposure to bisphenol-A overlooked? Int J Hyg Environ Health 2011,214(5):339-347. 10.1016/j.ijheh.2011.04.005
11. EFSA: Draft scientific opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs - exposure assessment. In EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids. Edited by: European Food Safety Authority E. Italy: Parma; 2013.
12. Vandenberg LN, Maffini MV, Sonnenschein C, Rubin BS, Soto AM: Bisphenol-A and the great divide: a review of controversies in the field of endocrine disruption. Endocr Rev 2009,30(1):75-95. 10.1210/er.2008-0021
13. Gould JC, Leonard LS, Maness SC, Wagner BL, Conner K, Zacharewski T, Safe S, McDonnell DP, Gaido KW: Bisphenol A interacts with the estrogen receptor a in a distinct manner from estradiol. Mol Cell Endocrinol 1998, 142:203-214. 10.1016/S0303-7207(98)00084-7
14. Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, Van Der Saag PT, van der Burg B, Gustafsson JA: Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998, 139:4252-4263.
15. Bulayeva NN, Watson CS: Xenoestrogen-induced ERK-1 and ERK-2 activation via multiple membrane-initiated signaling pathways. Environ Health Perspect 2004,112(15):1481-1487. 10.1289/ehp.7175
16. Thomas P, Dong J: Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. J Steroid Biochem Mol Biol 2006, 102:175-179. 10.1016/j.jsbmb.2006.09.017
17. Matsushima A, Kakuta Y, Teramoto T, Koshiba T, Liu X, Okada H, Tokunaga T, Kawabata S, Kimura M, Shimohigashi Y: Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma. J Biochem 2007,142(4):517-524. 10.1093/jb/mvm158
18. Alonso-Magdalena P, Laribi O, Ropero AB, Fuentes E, Ripoll C, Soria B, Nadal A: Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans. Environ Health Perspect 2005, 113:969-977. 10.1289/ehp.8002
19. Watson CS, Bulayeva NN, Wozniak AL, Alyea RA: Xenoestrogens are potent activators of nongenomic estrogenic responses. Steroids 2007, 72:124-134. 10.1016/j.steroids.2006.11.002
20. Watson CS, Bulayeva NN, Wozniak AL, Finnerty CC: Signaling from the membrane via membrane estrogen receptor-alpha: estrogens, xenoestrogens, and phytoestrogens. Steroids 2005, 70:364-371. 10.1016/j.steroids.2005.03.002
21. Wozniak AL, Bulayeva NN, Watson CS: Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-alpha mediated Ca++ fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environ Health Perspect 2005, 113:431-439. 10.1289/ehp.7505
22. Reif DM, Martin MT, Tan SW, Houck KA, Judson RS, Richard AM, Knudsen TB, Dix DJ, Kavlock RJ: Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environ Health Perspect 2010,118(12):1714-1720. 10.1289/ehp.1002180
23. Richter C, Birnbaum LS, Farabollini F, Newbold RR, Rubin BS, Talsness CE, Vandenbergh JG, Walser Kuntz DR, Vom Saal FS: In vivo effects of bisphenol A in laboratory rodent studies. Reprod Toxicol 2007,24(2):199-224. 10.1016/j.reprotox.2007.06.004
24. Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs DR Jr, Lee DH, Shioda T, Soto AM, Vom Saal FS, Welshons WV, Zoeller RT, Myers JP: Hormones and endocrine disrupting chemicals: low dose effects and non-monotonic dose responses. Endocr Rev 2012,33(3):378-455. 10.1210/er.2011-1050
25. Rubin BS: Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects. J Steroid Biochem Mol Biol 2011,172(1-2):27-34.
26. Vom Saal FS, Hughes C: An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ Health Perspect 2005, 113:926-933. 10.1289/ehp.7713
27. Vandenberg LN, Ehrlich S, Belcher SM, Ben-Jonathan N, Dolinoy DC, Hugo ER, Hunt PA, Newbold RR, Rubin BS, Saili KS, Soto AM, Wang HS, Vom Saal FS: Low dose effects of Bisphenol A: An integrated review of in vitro, laboratory animal and epidemiology studies. Endocr Disruptors 2013,1(1):e25078.
28. Chapin RE, Adams J, Boekelheide K, Gray LE Jr, Hayward SW, Lees PS, McIntyre BS, Portier KM, Schnorr TM, Selevan SG, Vandenbergh JG, Woskie SR: NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A. Birth Defects Res B Dev Reprod Toxicol 2008,83(3):157-395. 10.1002/bdrb.20147
29. Vandenberg LN, Chahoud I, Heindel JJ, Padmanabhan V, Paumgartten FJR, Schoenfelder G: Urine, serum and tissue biomonitoring studies indicate widespread exposure to bisphenol A. Environ Health Perspect 2010,118(8):1055-1070. 10.1289/ehp.0901716
30. Calafat AM, Ye X, Wong LY, Reidy JA, Needham JL: Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004. Environ Health Perspect 2008,116(1):39-44.
31. Becker K, Guen T, Seiwert M, Conrad A, Pick-Fuss H, Muller J, Wittassek M, Schulz C, Kolossa-Gehring M: GerES IV: Phthalate metabolites and bisphenol A in urine of German children. Int J Hyg Environ Health 2009,212(6):685-692. 10.1016/j.ijheh.2009.08.002
32. He Y, Miao M, Herrinton LJ, Wu C, Yuan W, Zhou Z, Li DK: Bisphenol A levels in blood and urine in a Chinese population and the personal factors affecting the levels. Environ Res 2009,109(5):629-633. 10.1016/j.envres.2009.04.003
33. Bushnik T, Haines D, Levallois P, Levesque J, Van Oostdam J, Viau C: Lead and bisphenol A concentrations in the Canadian population. Stat Can Health Rep 2010,21(3):7-18.
34. Calafat AM, Kuklenyik Z, Reidy JA, Caudill SP, Ekong J, Needham LL: Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environ Health Perspect 2005,113(4):391-395.
35. Sathyanarayana S, Braun JM, Yolton K, Liddy S, Lanphear BP: Case report: high prenatal bisphenol a exposure and infant neonatal neurobehavior. Environ Health Perspect 2011,119(8):1170-1175. 10.1289/ehp.1003064
36. Matthews JB, Twomey K, Zacharewski TR: In vitro and in vivo interactions of bisphenol A and its metabolite, bisphenol A glucuronide, with estrogen receptors alpha and beta. Chem Res Toxicol 2001,14(2):149-157. 10.1021/tx0001833
37. Vinas R, Goldblum RM, Watson CS: Rapid estrogenic signaling activities of the modified (chlorinated, sulfonated, and glucuronidated) endocrine disruptor bisphenol A. Endocr Disruptors 2013,1(1):e25411.
38. Doerge DR, Twaddle NC, Vanlandingham M, Fisher JW: Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats. Toxicol Appl Pharmacol 2010,247(2):158-165. 10.1016/j.taap.2010.06.008
39. Gayrard V, Lacroix MZ, Collet SH, Viguie C, Bousquet-Melou A, Toutain PL, Picard-Hagen N: High bioavailability of bisphenol A from sublingual exposure. Environ Health Perspect 2013,121(8):951-956.
40. Yokota H, Iwano H, Endo M, Kobayashi T, Inoue H, Ikushiro S, Yuasa A: Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver. Biochem J 1999, 340:405-409. 10.1042/0264-6021:3400405
41. Volkel W, Bittner N, Dekant W: Quantitation of bisphenol A and bisphenol A glucuronide in biological samples by high performance liquid chromatography-tandem mass spectrometry. Drug Metab Dispos 2005, 33:1748-1757. 10.1124/dmd.105.005454
42. Dekant W, Volkel W: Human exposure to bisphenol A by biomonitoring: methods, results and assessment of environmental exposures. Toxicol Appl Pharmacol 2008, 228:114-134. 10.1016/j.taap.2007.12.008
43. Lakind JS, Naiman DQ: Daily intake of bisphenol A and potential sources of exposure: 2005-2006 National Health and Nutrition Examination Survey. J Expo Sci Environ Epidemiol 2011,21(3):272-279. 10.1038/jes.2010.9
44. Sriphrapradang C, Chailurkit LO, Aekplakorn W, Ongphiphadhanakul B: Association between bisphenol A and abnormal free thyroxine level in men. Endocrine 2013,44(2):441-447. 10.1007/s12020-013-9889-y
45. Caserta D, Bordi G, Ciardo F, Marci R, La Rocca C, Tait S, Bergamasco B, Stecca L, Mantovani A, Guerranti C, Fanello EL, Perra G, Borghini F, Focardi SE, Moscarini M: The influence of endocrine disruptors in a selected population of infertile women. Gynecol Endocrinol 2013,29(5):444-447. 10.3109/09513590.2012.758702
46. Ye X, Zhou X, Wong LY, Calafat AM: Concentrations of bisphenol A and seven other phenols in pooled sera from 3-11 year old children: 2001-2002 National Health and Nutrition Examination Survey. Environ Sci Technol 2012,46(22):12664-12671. 10.1021/es303109c
47. Kosarac I, Kubwabo C, Lalonde K, Foster W: A novel method for the quantitative determination of free and conjugated bisphenol A in human maternal and umbilical cord blood serum using a two-step solid phase extraction and gas chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2012, 898:90-94.
48. Liao C, Kannan K: Determination of free and conjugated forms of bisphenol A in human urine and serum by liquid chromatography-tandem mass spectrometry. Environ Sci Technol 2012,46(9):5003-5009. 10.1021/es300115a
49. Gyllenhammar I, Glynn A, Darnerud PO, Lignell S, van Delft R, Aune M: 4-Nonylphenol and bisphenol A in Swedish food and exposure in Swedish nursing women. Environ Int 2012, 43:21-28.
50. Olsen L, Lind L, Lind PM: Associations between circulating levels of bisphenol A and phthalate metabolites and coronary risk in the elderly. Ecotoxicol Environ Saf 2012, 80:179-183.
51. Unal ER, Lynn T, Neidich J, Salazar D, Goetzl L, Baatz JE, Hulsey TC, Van Dolah R, Guillette LJ Jr, Newman R: Racial disparity in maternal and fetal-cord bisphenol A concentrations. J Perinatol 2012,32(11):844-850. 10.1038/jp.2012.12
52. Hanna CW, Bloom MS, Robinson WP, Kim D, Parsons PJ, Vom Saal FS, Taylor JA, Steuerwald AJ, Fujimoto VY: DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF. Hum Reprod 2012,27(5):1401-1410. 10.1093/humrep/des038
53. Olsen L, Lampa E, Birkholz DA, Lind L, Lind PM: Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Ecotoxicol Environ Saf 2012,75(1):242-248.
54. Bloom MS, Vom Saal FS, Kim D, Taylor JA, Lamb JD, Fujimoto VY: Serum unconjugated bisphenol A concentrations in men may influence embryo quality indicators during in vitro fertilization. Environ Toxicol Pharmacol 2011,32(2):319-323. 10.1016/j.etap.2011.06.003
55. Bloom MS, Kim D, Vom Saal FS, Taylor JA, Cheng G, Lamb JD, Fujimoto VY: Bisphenol A exposure reduces the estradiol response to gonadotropin stimulation during in vitro fertilization. Fertil Steril 2011,96(3):672-677. e672 10.1016/j.fertnstert.2011.06.063
56. Teeguarden JG, Calafat AM, Ye X, Doerge DR, Churchwell MI, Gunawan R, Graham MK: Twenty-four hour human urine and serum profiles of bisphenol a during high-dietary exposure. Toxicol Sci 2011,123(1):48-57. 10.1093/toxsci/kfr160
57. Kandaraki E, Chatzigeorgiou A, Livadas S, Palioura E, Economou F, Koutsilieris M, Palimeri S, Panidis D, Diamanti-Kandarakis E: Endocrine disruptors and polycystic ovary syndrome (PCOS): elevated serum levels of bisphenol A in women with PCOS. J Clin Endocrinol Metab 2011,96(3):E480-484. 10.1210/jc.2010-1658
58. Fujimoto VY, Kim D, Vom Saal FS, Lamb JD, Taylor JA, Bloom MS: Serum unconjugated bisphenol A concentrations in women may adversely influence oocyte quality during in vitro fertilization. Fertil Steril 2011,95(5):1816-1819. 10.1016/j.fertnstert.2010.11.008
59. Wan Y, Choi K, Kim S, Ji K, Chang H, Wiseman S, Jones PD, Khim JS, Park S, Park J, Lam MH, Giesy JP: Hydroxylated polybrominated diphenyl ethers and bisphenol A in pregnant women and their matching fetuses: placental transfer and potential risks. Environ Sci Technol 2010,44(13):5233-5239. 10.1021/es1002764
60. Cobellis L, Colacurci N, Trabucco E, Carpentiero C, Grumetto L: Measurement of bisphenol A and bisphenol B levels in human blood sera from healthy and endometriotic women. Biomed Chromatogh 2009,23(11):1186-1190. 10.1002/bmc.1241
61. Gerona RR, Woodruff TJ, Dickenson CA, Pan J, Schwartz JM, Sen S, Friesen M, Fujimoto VY, Hunt PA: BPA, BPA glucuronide, and BPA sulfate in mid-gestation umbilical cord serum in a northern California cohort. Environ Sci Technol 2013,47(21):12477-12485. 10.1021/es402764d
62. Zhang T, Sun H, Kannan K: Blood and Urinary Bisphenol A Concentrations in Children, Adults, and Pregnant Women from China: Partitioning between Blood and Urine and Maternal and Fetal Cord Blood. Environ Sci Technol 2013,47(9):4686-4694. 10.1021/es303808b
63. Shaw SD, Berger ML, Harris JH, Yun SH, Wu Q, Liao C, Blum A, Stefani A, Kannan K: Persistent organic pollutants including polychlorinated and polybrominated dibenzo-p-dioxins and dibenzofurans in firefighters from Northern California. Chemosphere 2013,91(10):1386-1394. 10.1016/j.chemosphere.2012.12.070
64. Kaddar N, Bendridi N, Harthe C, Rolland De Ravel M, Bienvenu AL, Cuilleron CY, Mappus E, Pugeat M, Dechaud H: Development of a radioimmunoassay for the measurement of Bisphenol A in biological samples. Anal Chim Acta 2009, 645:1-4. 10.1016/j.aca.2009.04.036
65. Lee YJ, Ryu H-Y, Kim H-K, Min CS, Lee JH, Kim E, Nam BH, Park JH, Jung JY, Jang DD, Park EY, Lee KH, Ma JY, Won HS, Im MW, Leem JH, Hong YC, Yoon HS: Maternal and fetal exposure to bisphenol A in Korea. Reprod Toxicol 2008, 25:413-419. 10.1016/j.reprotox.2008.05.058
66. Fung EYK, Ewoldsen NO, ST Germain HA, Marx DB, Miaw CL, Siew C, Chou HN, Gruninger SE, Meyer DM: Pharmacokinetics of bisphenol A released from a dental sealant. JADA 2000, 131:51-58.
67. Ye X, Wong LY, Jia LT, Needham LL, Calafat AM: Stability of the conjugated species of environmental phenols and parabens in human serum. Environ Int 2009,35(8):1160-1163. 10.1016/j.envint.2009.07.011
68. Vandenberg LN, Chahoud I, Padmanabhan V, Paumgartten FJR, Schoenfelder G: Biomonitoring studies should be used by regulatory agencies to assess human exposure levels and safety of Bisphenol A. Environ Health Perspect 2010,118(8):1051-1054. 10.1289/ehp.0901717
69. EFSA: Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to 2,2-BIS(4-HYDROXYPHENYL)PROPANE. The EFSA J 2006, 428:1-75.
70. EFSA: Toxicokinetics of Bisphenol A: scientific opinion of the panel on food additives, flavourings, processing aids and materials in contact with food (AFC). The EFSA J 2008, 759:1-10.
71. Mielke H, Gundert-Remy U: Bisphenol A levels in blood depend on age and exposure. Toxicol Lett 2009,190(1):32-40. 10.1016/j.toxlet.2009.06.861
72. Ye X, Zhou X, Hennings R, Kramer J, Calafat AM: Potential external contamination with bisphenol A and other ubiquitous organic environmental chemicals during biomonitoring analysis: An elusive laboratory challenge. Environ Health Perspect 2013,121(3):283-286. 10.1289/ehp.1206093
73. Schoenfelder G, Wittfoht W, Hopp H, Talsness CE, Paul M, Chahoud I: Parent bisphenol A accumulation in the human maternal-fetal-placental unit. Environ Health Perspect 2002, 110:A703-A707. 10.1289/ehp.021100703
74. Padmanabhan V, Siefert K, Ransom S, Johnson T, Pinkerton J, Anderson L, Tao L, Kannao K: Maternal bisphenol-A levels at delivery: a looming problem? J Perinatol 2008, 28:258-263. 10.1038/sj.jp.7211913
75. Taylor JA, Vom Saal FS, Welshons WV, Drury B, Rottinghaus G, Hunt PA, Vandevoort CA: Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure. Environ Health Perspect 2011,119(4):422-430.
76. Twaddle NC, Churchwell MI, Vanlandingham M, Doerge DR: Quantification of deuterated bisphenol A in serum, tissues, and excreta from adult Sprague-Dawley rats using liquid chromatography with tandem mass spectrometry. Rapid Commun Mass Spectrom 2010,24(20):3011-3020. 10.1002/rcm.4733
77. Patterson TA, Twaddle NC, Roegge CS, Callicott RJ, Fisher JW, Doerge DR: Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys. Toxicol Appl Pharmacol 2012,267(1):41-48.
78. Volkel W, Colnot T, Csanady GA, Filser JG, Dekant W: Metabolism and kinetics of bisphenol a in humans at low doses following oral administration. Chem Res Toxicol 2002,15(10):1281-1287. 10.1021/tx025548t
79. Kang JH, Kondo F, Katayama Y: Human exposure to bisphenol A. Toxicology 2006,226(2-3):79-89.
80. Ouichi K, Watanabe S: Measurement of bisphenol A in human urine using liquid chromatography with multi-channel coulometric electrochemical detection. J Chromatogr B 2002, 780:365-370. 10.1016/S1570-0232(02)00547-0
81. Miyamoto K, Kotake M: Estimation of daily bisphenol A intake of Japanese individuals with emphasis on uncertainty and variability. Environ Sci 2006,13(1):15-29.
82. Kamrin MA: Bisphenol A: a scientific evaluation. MedGenMed 2004,6(3):7.
83. Teeguarden JG, Hanson Drury S, Fisher JW, Doerge DR: Are typical human serum BPA concentrations measureable and sufficient to be estrogenic in the general population? Food Chem Toxicol 2013, 62:949-963.
84. Vandenberg LN, Hunt PA, Myers JP, Vom Saal FS: Human exposures to bisphenol A: mismatches between data and assumptions. Rev Environ Health 2013,28(1):37-58.
85. Stahlhut RW, Welshons WV, Swan SH: Bisphenol A data in NHANES suggest longer than expected half-life, substantial nonfood exposure, or both. Environ Health Perspect 2009,117(5):784-789. 10.1289/ehp.0800376
86. Zalko D, Soto AM, Dolo L, Dorio C, Ratahao E, Debrauwer L, Faure R, Cravedi J-P: Biotransformations of bisphenol A in a mammalian model: answers and new questions raised by low-dose metabolic fate studies in pregnant CD1 mice. Environ Health Perspect 2003, 111:309-319.
87. Prins GS, Ye SH, Birch L, Ho SM, Kannan K: Serum bisphenol A pharmacokinetics and prostate neoplastic responses following oral and subcutaneous exposures in neonatal Sprague-Dawley rats. Reprod Toxicol 2011,31(1):1-9. 10.1016/j.reprotox.2010.09.009
88. Yang X, Doerge DR, Fisher JW: Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model. Toxicol Appl Pharmacol 2013,270(1):45-59. 10.1016/j.taap.2013.03.022
89. Calafat AM, Ye X, Silva MJ, Kuklenyik Z, Needham LL: Human exposure assessment to environmental chemicals using biomonitoring. Int J Androl 2006,29(1):166-171. discussion 181-165 10.1111/j.1365-2605.2005.00570.x
90. Needham LL, Calafat AM, Barr DB: Assessing developmental toxicant exposures via biomonitoring. Basic Clin Pharmacol Toxicol 2008, 102:100-108. 10.1111/j.1742-7843.2007.00185.x
91. Vom Saal FS, Prins GS, Welshons WV: Report of very low real-world exposure to bisphenol A is unwarranted based on a lack of data and flawed assumptions. Toxicol Sci 2012,125(1):318-320. author reply 321-315 10.1093/toxsci/kfr273