-
1
-
-
77951776390
-
Genetics, pathogenesis and clinical interventions in type 1 diabetes
-
Bluestone J.A., Herold K., Eisenbarth G. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature 2010, 464:1293-1300.
-
(2010)
Nature
, vol.464
, pp. 1293-1300
-
-
Bluestone, J.A.1
Herold, K.2
Eisenbarth, G.3
-
2
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
van Belle T.L., Coppieters K.T., von Herrath M.G. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol. Rev. 2011, 91:79-118.
-
(2011)
Physiol. Rev.
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
3
-
-
0031871335
-
An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
-
Rabinovitch A. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes Metab. Rev. 1998, 14:129-151.
-
(1998)
Diabetes Metab. Rev.
, vol.14
, pp. 129-151
-
-
Rabinovitch, A.1
-
4
-
-
0037731769
-
What it takes to become an effector T cell: the process, the cells involved, and the mechanisms
-
Santana M.A., Rosenstein Y. What it takes to become an effector T cell: the process, the cells involved, and the mechanisms. J. Cell. Physiol. 2003, 195:392.
-
(2003)
J. Cell. Physiol.
, vol.195
, pp. 392
-
-
Santana, M.A.1
Rosenstein, Y.2
-
6
-
-
77957606887
-
Beta-cell growth and regeneration: replication is only part of the story
-
Bonner-Weir S., Li W.C., Ouziel-Yahalom L., Guo L., Weir G.C., Sharma A. Beta-cell growth and regeneration: replication is only part of the story. Diabetes 2010, 59:2340-2348.
-
(2010)
Diabetes
, vol.59
, pp. 2340-2348
-
-
Bonner-Weir, S.1
Li, W.C.2
Ouziel-Yahalom, L.3
Guo, L.4
Weir, G.C.5
Sharma, A.6
-
7
-
-
84887017618
-
Anti-cytokine therapies in T1D: concepts and strategies
-
Nepom G.T., Ehlers M., Mandrup-Poulsen T. Anti-cytokine therapies in T1D: concepts and strategies. Clin. Immunol. 2013, 149:279-285.
-
(2013)
Clin. Immunol.
, vol.149
, pp. 279-285
-
-
Nepom, G.T.1
Ehlers, M.2
Mandrup-Poulsen, T.3
-
8
-
-
84903524188
-
The regulation of pre- and post-maturational plasticity of mammalian islet cell mass
-
Mezza T., Kulkarni R.N. The regulation of pre- and post-maturational plasticity of mammalian islet cell mass. Diabetologia 2014, 57:1291-1303.
-
(2014)
Diabetologia
, vol.57
, pp. 1291-1303
-
-
Mezza, T.1
Kulkarni, R.N.2
-
9
-
-
13244291654
-
CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule
-
Motterlini R., Sawle P., Hammad J., Bains S., Alberto R., Foresti R., et al. CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule. FASEB J 2005, 19:284-286.
-
(2005)
FASEB J
, vol.19
, pp. 284-286
-
-
Motterlini, R.1
Sawle, P.2
Hammad, J.3
Bains, S.4
Alberto, R.5
Foresti, R.6
-
10
-
-
43349092136
-
Use of carbon monoxide as a therapeutic agent: promises and challenges
-
Foresti R., Bani-Hani M.G., Motterlini R. Use of carbon monoxide as a therapeutic agent: promises and challenges. Intensive Care Med. 2008, 34:649-658.
-
(2008)
Intensive Care Med.
, vol.34
, pp. 649-658
-
-
Foresti, R.1
Bani-Hani, M.G.2
Motterlini, R.3
-
11
-
-
27744492554
-
Therapeutic applications of carbon monoxide-releasing molecules (CO-RMs)
-
Motterlini R., Mann B.E., Foresti R. Therapeutic applications of carbon monoxide-releasing molecules (CO-RMs). Expert Opin. Investig. Drugs 2005, 14:1305-1318.
-
(2005)
Expert Opin. Investig. Drugs
, vol.14
, pp. 1305-1318
-
-
Motterlini, R.1
Mann, B.E.2
Foresti, R.3
-
12
-
-
36749043642
-
Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities
-
Motterlini R. Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities. Biochem. Soc. Trans. 2007, 35:1142-1146.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 1142-1146
-
-
Motterlini, R.1
-
13
-
-
79551718102
-
Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1
-
Fagone P., Mangano K., Quattrocchi C., Motterlini R., Di Marco R., Magro G., et al. Prevention of clinical and histological signs of proteolipid protein (PLP)-induced experimental allergic encephalomyelitis (EAE) in mice by the water-soluble carbon monoxide-releasing molecule (CORM)-A1. Clin. Exp. Immunol. 2011, 163:368-374.
-
(2011)
Clin. Exp. Immunol.
, vol.163
, pp. 368-374
-
-
Fagone, P.1
Mangano, K.2
Quattrocchi, C.3
Motterlini, R.4
Di Marco, R.5
Magro, G.6
-
14
-
-
84891824888
-
Chronic carbon monoxide treatment attenuates development of obesity and remodels adipocytes in mice fed a high-fat diet
-
Hosick P.A., AlAmodi A.A., Storm M.V., Gousset M.U., Pruett B.E., Gray W, et al. Chronic carbon monoxide treatment attenuates development of obesity and remodels adipocytes in mice fed a high-fat diet. Int. J. Obes. (Lond.) 2014, 38:132-139.
-
(2014)
Int. J. Obes. (Lond.)
, vol.38
, pp. 132-139
-
-
Hosick, P.A.1
AlAmodi, A.A.2
Storm, M.V.3
Gousset, M.U.4
Pruett, B.E.5
Gray, W.6
-
15
-
-
84932151498
-
Protective role of HO-1 and carbon monoxide in ethanol-induced cell death in hepatocytes and liver injury in mice
-
Bakhautdin B., Das D., Mandal P., Roychowdhury S., Danner J., Bush K., et al. Protective role of HO-1 and carbon monoxide in ethanol-induced cell death in hepatocytes and liver injury in mice. J. Hepatol. 2014, (pii: S0168-8278(14)00402-4). 10.1016/j.jhep.2014.06.007.
-
(2014)
J. Hepatol.
-
-
Bakhautdin, B.1
Das, D.2
Mandal, P.3
Roychowdhury, S.4
Danner, J.5
Bush, K.6
-
16
-
-
84898600879
-
Pharmacological application of carbon monoxide ameliorates islet-directed autoimmunity in mice via anti-inflammatory and anti-apoptotic effects
-
Nikolic I., Saksida T., Mangano K., Vujicic M., Stojanovic I., Nicoletti F., et al. Pharmacological application of carbon monoxide ameliorates islet-directed autoimmunity in mice via anti-inflammatory and anti-apoptotic effects. Diabetologia 2014, 57:980-990.
-
(2014)
Diabetologia
, vol.57
, pp. 980-990
-
-
Nikolic, I.1
Saksida, T.2
Mangano, K.3
Vujicic, M.4
Stojanovic, I.5
Nicoletti, F.6
-
17
-
-
70350749391
-
Regulatory T cells and ST2 signaling control diabetes induction with multiple low doses of streptozotocin
-
Zdravkovic N., Shahin A., Arsenijevic N., Lukic M.L., Mensah-Brown E.P. Regulatory T cells and ST2 signaling control diabetes induction with multiple low doses of streptozotocin. Mol. Immunol. 2009, 47:28-36.
-
(2009)
Mol. Immunol.
, vol.47
, pp. 28-36
-
-
Zdravkovic, N.1
Shahin, A.2
Arsenijevic, N.3
Lukic, M.L.4
Mensah-Brown, E.P.5
-
18
-
-
84872378799
-
ST2 gene-deletion reveals a role of Foxp3+ regulatory T cells in diabetes modulation in BALB/c mice
-
Zdravkovic N., Pavlovic S., Zdravkovic V., Pejnovic N., Arsenijevic N., Lukic M.L. ST2 gene-deletion reveals a role of Foxp3+ regulatory T cells in diabetes modulation in BALB/c mice. Transl. Res. 2013, 161:118-129.
-
(2013)
Transl. Res.
, vol.161
, pp. 118-129
-
-
Zdravkovic, N.1
Pavlovic, S.2
Zdravkovic, V.3
Pejnovic, N.4
Arsenijevic, N.5
Lukic, M.L.6
-
19
-
-
84879356078
-
Foxp3+ regulatory T cells in mouse models of type 1 diabetes
-
Petzold C., Riewaldt J., Watts D., Sparwasser T., Schallenberg S., Kretschmer K. Foxp3+ regulatory T cells in mouse models of type 1 diabetes. J. Diabetes Res. 2013, 2013:940710.
-
(2013)
J. Diabetes Res.
, vol.2013
, pp. 940710
-
-
Petzold, C.1
Riewaldt, J.2
Watts, D.3
Sparwasser, T.4
Schallenberg, S.5
Kretschmer, K.6
-
20
-
-
33750833099
-
Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+ Foxp3+ regulatory T cells
-
Brode S., Raine T., Zaccone P., Cooke A. Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+ Foxp3+ regulatory T cells. J. Immunol. 2006, 177:6603-6612.
-
(2006)
J. Immunol.
, vol.177
, pp. 6603-6612
-
-
Brode, S.1
Raine, T.2
Zaccone, P.3
Cooke, A.4
-
21
-
-
12344335548
-
Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression
-
Choi B.M., Pae H.O., Jeong Y.R., Kim Y.M., Chung H.T. Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression. Biochem. Biophys. Res. Commun. 2005, 327:1066-1071.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.327
, pp. 1066-1071
-
-
Choi, B.M.1
Pae, H.O.2
Jeong, Y.R.3
Kim, Y.M.4
Chung, H.T.5
-
22
-
-
17844374374
-
An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells
-
Brusko T.M., Wasserfall C.H., Agarwal A., Kapturczak M.H., Atkinson M.A. An integral role for heme oxygenase-1 and carbon monoxide in maintaining peripheral tolerance by CD4+CD25+ regulatory T cells. J. Immunol. 2005, 174:5181-5186.
-
(2005)
J. Immunol.
, vol.174
, pp. 5181-5186
-
-
Brusko, T.M.1
Wasserfall, C.H.2
Agarwal, A.3
Kapturczak, M.H.4
Atkinson, M.A.5
-
23
-
-
38449090623
-
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes
-
Tritt M., Sgouroudis E., d'Hennezel E., Albanese A., Piccirillo C.A. Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. Diabetes 2008, 57:113-123.
-
(2008)
Diabetes
, vol.57
, pp. 113-123
-
-
Tritt, M.1
Sgouroudis, E.2
d'Hennezel, E.3
Albanese, A.4
Piccirillo, C.A.5
-
24
-
-
33845944537
-
FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to nonlymphoid tissue homing receptors in secondary lymphoid tissues
-
Lee J.H., Kang S.G., Kim C.H. FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to nonlymphoid tissue homing receptors in secondary lymphoid tissues. J. Immunol. 2007, 178:301-311.
-
(2007)
J. Immunol.
, vol.178
, pp. 301-311
-
-
Lee, J.H.1
Kang, S.G.2
Kim, C.H.3
-
25
-
-
28044432292
-
Autoimmune destruction of pancreatic β cells
-
Ji-Won Y., Hee-Sook J. Autoimmune destruction of pancreatic β cells. Am. J. Ther. 2005, 12:580-591.
-
(2005)
Am. J. Ther.
, vol.12
, pp. 580-591
-
-
Ji-Won, Y.1
Hee-Sook, J.2
-
26
-
-
0029014952
-
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4 T cells
-
Macatonia S.E., Hosken N.A., Litton M., Vieira P., Hsieh C.S., Culpepper J.A., et al. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4 T cells. J. Immunol. 1995, 154:5071-5079.
-
(1995)
J. Immunol.
, vol.154
, pp. 5071-5079
-
-
Macatonia, S.E.1
Hosken, N.A.2
Litton, M.3
Vieira, P.4
Hsieh, C.S.5
Culpepper, J.A.6
-
27
-
-
0030829552
-
Role of interleukin 12 and costimulators in T cell anergy in vivo
-
Van Parijs L., Perez V.L., Biuckians A., Maki R.G., London C.A., Abbas A.K. Role of interleukin 12 and costimulators in T cell anergy in vivo. J. Exp. Med. 1997, 186:1119-1128.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1119-1128
-
-
Van Parijs, L.1
Perez, V.L.2
Biuckians, A.3
Maki, R.G.4
London, C.A.5
Abbas, A.K.6
-
28
-
-
61449255986
-
Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity
-
Remy S., Blancou P., Tesson L., Tardif V., Brion R., Royer P.J., et al. Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity. J. Immunol. 2009, 182:1877-1884.
-
(2009)
J. Immunol.
, vol.182
, pp. 1877-1884
-
-
Remy, S.1
Blancou, P.2
Tesson, L.3
Tardif, V.4
Brion, R.5
Royer, P.J.6
-
29
-
-
84872488294
-
Carbon monoxide-treated dendritic cells decrease β1-integrin induction on CD8+ T cells and protect from type 1 diabetes
-
Simon T., Pogu S., Tardif V., Rigaud K., Rémy S., Piaggio E., et al. Carbon monoxide-treated dendritic cells decrease β1-integrin induction on CD8+ T cells and protect from type 1 diabetes. Eur. J. Immunol. 2013, 43:209-218.
-
(2013)
Eur. J. Immunol.
, vol.43
, pp. 209-218
-
-
Simon, T.1
Pogu, S.2
Tardif, V.3
Rigaud, K.4
Rémy, S.5
Piaggio, E.6
-
30
-
-
1842529311
-
Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production
-
Pae H.O., Oh G.S., Choi B.M., Chae S.C., Kim Y.M., Chung K.R., et al. Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J. Immunol. 2004, 172:4744-4751.
-
(2004)
J. Immunol.
, vol.172
, pp. 4744-4751
-
-
Pae, H.O.1
Oh, G.S.2
Choi, B.M.3
Chae, S.C.4
Kim, Y.M.5
Chung, K.R.6
-
31
-
-
77955012740
-
IL-2-deprivation and TGF-β are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation
-
Wang G., Khattar M., Guo Z., Miyahara Y., Linkes S.P., Sun Z., et al. IL-2-deprivation and TGF-β are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation. Immunol. Lett. 2010, 132:61-68.
-
(2010)
Immunol. Lett.
, vol.132
, pp. 61-68
-
-
Wang, G.1
Khattar, M.2
Guo, Z.3
Miyahara, Y.4
Linkes, S.P.5
Sun, Z.6
-
32
-
-
43249097073
-
CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells
-
Perruche S., Zhang P., Liu Y., Saas P., Bluestone J.A., Chen W. CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells. Nat. Med. 2008, 14:528-535.
-
(2008)
Nat. Med.
, vol.14
, pp. 528-535
-
-
Perruche, S.1
Zhang, P.2
Liu, Y.3
Saas, P.4
Bluestone, J.A.5
Chen, W.6
-
33
-
-
0034022196
-
Expression of functional IL-2 receptor on mature splenic dendritic cells
-
Fukao T., Koyasu S. Expression of functional IL-2 receptor on mature splenic dendritic cells. Eur. J. Immunol. 2000, 30:1453-1457.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1453-1457
-
-
Fukao, T.1
Koyasu, S.2
-
34
-
-
33751512226
-
Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response
-
Sanarico N., Ciaramella A., Sacchi A., Bernasconi D., Bossu' P., Mariani F., et al. Human monocyte-derived dendritic cells differentiated in the presence of IL-2 produce proinflammatory cytokines and prime Th1 immune response. J. Leukoc. Biol. 2006, 80:555-562.
-
(2006)
J. Leukoc. Biol.
, vol.80
, pp. 555-562
-
-
Sanarico, N.1
Ciaramella, A.2
Sacchi, A.3
Bernasconi, D.4
Bossu', P.5
Mariani, F.6
-
35
-
-
30944441065
-
Transforming growth factor-β pathway: role in pancreas development and pancreatic disease
-
Rane S.G., Lee J.H., Lin H.M. Transforming growth factor-β pathway: role in pancreas development and pancreatic disease. Cytokine Growth Factor Rev. 2006, 17:107-119.
-
(2006)
Cytokine Growth Factor Rev.
, vol.17
, pp. 107-119
-
-
Rane, S.G.1
Lee, J.H.2
Lin, H.M.3
-
36
-
-
84886545834
-
A smad signaling network regulates islet cell proliferation
-
El-Gohary Y., Tulachan S., Wiersch J., Guo P., Welsh C., Prasadan K., et al. A smad signaling network regulates islet cell proliferation. Diabetes 2014, 63:224-236.
-
(2014)
Diabetes
, vol.63
, pp. 224-236
-
-
El-Gohary, Y.1
Tulachan, S.2
Wiersch, J.3
Guo, P.4
Welsh, C.5
Prasadan, K.6
-
38
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
-
Otterbein L.E., Bach F.H., Alam J., Soares M., Tao L.H., Wysk M., et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 2000, 6:422-428.
-
(2000)
Nat. Med.
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
Soares, M.4
Tao, L.H.5
Wysk, M.6
-
39
-
-
0141707960
-
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1
-
Morse D., Pischke S.E., Zhou Z., Davis R.J., Flavell R.A., Loop T., et al. Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1. J. Biol. Chem. 2003, 278:36993-36998.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36993-36998
-
-
Morse, D.1
Pischke, S.E.2
Zhou, Z.3
Davis, R.J.4
Flavell, R.A.5
Loop, T.6
-
40
-
-
84875976523
-
Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway
-
Schallner N., Romaio C.C., Biermann J., Lagre'ze W.A., Otterbein L.E., Buerkle H., et al. Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway. PLOS ONE 2013, 8:e60672.
-
(2013)
PLOS ONE
, vol.8
, pp. e60672
-
-
Schallner, N.1
Romaio, C.C.2
Biermann, J.3
Lagre'ze, W.A.4
Otterbein, L.E.5
Buerkle, H.6
-
41
-
-
41649092955
-
The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels
-
Hou S., Xu R., Heinemann S.H., Hoshi T. The RCK1 high-affinity Ca2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:4039-4043.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 4039-4043
-
-
Hou, S.1
Xu, R.2
Heinemann, S.H.3
Hoshi, T.4
|