IL-2-deprivation and TGF-β are two non-redundant suppressor mechanisms of CD4+CD25+ regulatory T cell which jointly restrain CD4+CD25- cell activation

Immunology Letters

Volumn 132, Issue 1-2, 2010, Pages 61-68

  Wang, Guohua ^a,b   Khattar, Mithun ^a   Guo, Zhiyong ^a,c   Miyahara, Yoshihiro ^a   Linkes, Sean P ^a   Sun, Zongquan ^b   He, Xiaoshun ^c   Stepkowski, Stanislaw M ^a   Chen, Wenhao ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

IL 2; Regulatory T cell; Suppressor mechanism; TGF

Indexed keywords

CALCIUM; INTERLEUKIN 2; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA; CD24 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; GENE OVEREXPRESSION; IMMUNE DEFICIENCY; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM;

ANIMALS; ANTIGENS, CD24; CELLS, CULTURED; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955012740     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2010.06.001     Document Type: Article

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