Protective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in mice

Journal of Hepatology

Volumn 61, Issue 5, 2014, Pages 1029-1037

  Bakhautdin, Bakytzhan ^a,c   Das, Dola ^a   Mandal, Palash ^a,d   Roychowdhury, Sanjoy ^a   Danner, Jazmine ^a   Bush, Katelyn ^a   Pollard, Katherine ^a   Kaspar, James W ^a   Li, Wei ^b   Salomon, Robert G ^b   McMullen, Megan R ^a   Nagy, Laura E ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c FATIH UNIVERSITY   (Turkey)

^d BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Alcoholic liver disease; Apoptosis; Heme oxygenase 1; Hepatocytes; Necroptosis

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; BILIVERDIN; CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE; CYTOCHROME P450 2E1; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEME OXYGENASE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LIVER PROTECTIVE AGENT; MESSENGER RNA; PROTOPORPHYRIN COBALT; SODIUM BORANOCARBONATE; SODIUM CHLORIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BORANE DERIVATIVE; CARBONIC ACID DERIVATIVE; CYTOKINE; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTOPORPHYRIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY ASSAY; ENZYME ACTIVITY; ENZYME INDUCTION; IMMUNE RESPONSE; INFLAMMATION; LIVER CELL; LIVER CELL CULTURE; LIVER CELL DAMAGE; LIVER FUNCTION; LIVER PROTECTION; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEATOSIS; TREATMENT OUTCOME; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; FEMALE; GENE EXPRESSION; GENETICS; MALE; METABOLISM; PATHOLOGY; RAT; TOXIC HEPATITIS; WISTAR RAT;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BORANES; CARBON MONOXIDE; CARBONATES; CELL DEATH; CELLS, CULTURED; CYTOKINES; DRUG-INDUCED LIVER INJURY; ENZYME INDUCTION; ETHANOL; FEMALE; GENE EXPRESSION; HEME OXYGENASE-1; HEPATOCYTES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PROTOPORPHYRINS; RATS; RATS, WISTAR; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84932151498     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.06.007     Document Type: Article

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