Carbon Monoxide Abrogates Ischemic Insult to Neuronal Cells via the Soluble Guanylate Cyclase-cGMP Pathway

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Schallner, Nils ^a   Romão, Carlos C ^b,d   Biermann, Julia ^a   Lagrèze, Wolf A ^a   Otterbein, Leo E ^c   Buerkle, Hartmut ^a   Loop, Torsten ^a   Goebel, Ulrich ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c HARVARD MEDICAL SCHOOL   (United States)

^d INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ALF 186; CARBON MONOXIDE; CASPASE 3; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE 1; GUANYLATE CYCLASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MOLYBDENUM COMPLEX; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; DRUG STRUCTURE; FEMALE; FLOW CYTOMETRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPROTECTION; NONHUMAN; RAT; RETINA GANGLION CELL; RETINA ISCHEMIA; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CARBON MONOXIDE; CELL LINE, TUMOR; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GUANYLATE CYCLASE; HUMANS; MALE; MOLYBDENUM; NADPH OXIDASE; NEURONS; NEUROPROTECTIVE AGENTS; ORGANOMETALLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPERFUSION INJURY; RETINAL GANGLION CELLS; ROTENONE; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84875976523     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060672     Document Type: Article

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