Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation

Cell Death and Disease

Volumn 5, Issue 10, 2014, Pages

  Francis, R J ^a   Butler, R E ^a   Stewart, G R ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALPAIN; DNA; EARLY SECRETORY ANTIGENIC TARGET 6; LEUKOCIDIN; MYELOPEROXIDASE; PHOSPHATIDYLSERINE; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CALCIUM; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS;

AGED; ANTIGEN FUNCTION; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL SECRETION SYSTEM; BACTERIAL TRANSMISSION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL MEMBRANE; CELL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; ENZYME LOCALIZATION; EXTRACELLULAR TRAP; FLOW CYTOMETRY; GRANULOMA; HUMAN; HUMAN CELL; INFLAMMATION; MYCOBACTERIUM TUBERCULOSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS; TYPE VII SECRETION SYSTEM; ENZYME ACTIVATION; EXOCYTOSIS; METABOLISM; NECROSIS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CALCIUM; CALPAIN; ENZYME ACTIVATION; EXOCYTOSIS; EXTRACELLULAR TRAPS; HUMANS; LEUKOCIDINS; MYCOBACTERIUM TUBERCULOSIS; NECROSIS; NEUTROPHILS; PHOSPHATIDYLSERINES;

EID: 84926390459     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.394     Document Type: Article

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