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Volumn 6, Issue MAR, 2015, Pages

Transcriptional response of polycomb group genes to status epilepticus in mice is modified by prior exposure to epileptic preconditioning

Author keywords

Epileptic tolerance; Hippocampal sclerosis; Neuroprotection; Polycomb; Temporal lobe epilepsy

Indexed keywords

BMI1 PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; SIRTUIN 1; TRANSCRIPTION FACTOR YY1;

EID: 84926354715     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2015.00046     Document Type: Article
Times cited : (19)

References (65)
  • 1
    • 77958526499 scopus 로고    scopus 로고
    • Epigenetic regulation of the neural transcriptome: the meaning of the marks
    • Meaney MJ, Ferguson-Smith AC. Epigenetic regulation of the neural transcriptome: the meaning of the marks. Nat Neurosci (2010) 13:1313-8. doi:10.1038/nn1110-1313
    • (2010) Nat Neurosci , vol.13 , pp. 1313-1318
    • Meaney, M.J.1    Ferguson-Smith, A.C.2
  • 2
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron (2007) 53:857-69. doi:10.1016/j.neuron.2007.02.022
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 3
    • 84869094911 scopus 로고    scopus 로고
    • Histone regulation in the CNS: basic principles of epigenetic plasticity
    • Maze I, Noh K-M, Allis CD. Histone regulation in the CNS: basic principles of epigenetic plasticity. Neuropsychopharmacology (2013) 38:3-22. doi:10.1038/npp.2012.124
    • (2013) Neuropsychopharmacology , vol.38 , pp. 3-22
    • Maze, I.1    Noh, K.-M.2    Allis, C.D.3
  • 4
    • 70449725209 scopus 로고    scopus 로고
    • Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
    • Urdinguio RG, Sanchez-Mut JV, Esteller M. Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. Lancet Neurol (2009) 8:1056-72. doi:10.1016/S1474-4422(09)70262-5
    • (2009) Lancet Neurol , vol.8 , pp. 1056-1072
    • Urdinguio, R.G.1    Sanchez-Mut, J.V.2    Esteller, M.3
  • 5
    • 79958170373 scopus 로고    scopus 로고
    • DNA methylation in neurodegenerative disorders: a missing link between genome and environment?
    • Iraola-Guzmán S, Estivill X, Rabionet R. DNA methylation in neurodegenerative disorders: a missing link between genome and environment? Clin Genet (2011) 80:1-14. doi:10.1111/j.1399-0004.2011.01673.x
    • (2011) Clin Genet , vol.80 , pp. 1-14
    • Iraola-Guzmán, S.1    Estivill, X.2    Rabionet, R.3
  • 6
    • 79960108626 scopus 로고    scopus 로고
    • The methylation hypothesis: do epigenetic chromatin modifications play a role in epileptogenesis?
    • Kobow K, Blümcke I. The methylation hypothesis: do epigenetic chromatin modifications play a role in epileptogenesis? Epilepsia (2011) 52(Suppl 4):15-9. doi:10.1111/j.1528-1167.2011.03145.x
    • (2011) Epilepsia , vol.52 , pp. 15-19
    • Kobow, K.1    Blümcke, I.2
  • 7
    • 84866179730 scopus 로고    scopus 로고
    • Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy
    • Zhu Q, Wang L, Zhang Y, Zhao F-H, Luo J, Xiao X, et al. Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy. J Mol Neurosci (2012) 46:420-6. doi:10.1007/s12031-011-9602-7
    • (2012) J Mol Neurosci , vol.46 , pp. 420-426
    • Zhu, Q.1    Wang, L.2    Zhang, Y.3    Zhao, F.-H.4    Luo, J.5    Xiao, X.6
  • 8
    • 39749152283 scopus 로고    scopus 로고
    • DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function
    • Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, et al. DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet (2008) 17:690-709. doi:10.1093/hmg/ddm341
    • (2008) Hum Mol Genet , vol.17 , pp. 690-709
    • Jin, B.1    Tao, Q.2    Peng, J.3    Soo, H.M.4    Wu, W.5    Ying, J.6
  • 9
    • 0036812485 scopus 로고    scopus 로고
    • Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus
    • Huang Y, Doherty JJ, Dingledine R. Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J Neurosci (2002) 22:8422-8.
    • (2002) J Neurosci , vol.22 , pp. 8422-8428
    • Huang, Y.1    Doherty, J.J.2    Dingledine, R.3
  • 10
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova NM, Kumar A, Nestler EJ. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci (2004) 24:5603-10. doi:10.1523/JNEUROSCI.0589-04.2004
    • (2004) J Neurosci , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1    Kumar, A.2    Nestler, E.J.3
  • 11
    • 84904893871 scopus 로고    scopus 로고
    • Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex
    • Park HG, Yu HS, Park S, Ahn YM, Kim YS, Kim SH. Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex. Int J Neuropsychopharmacol (2014) 17:1487-500. doi:10.1017/S1461145714000248
    • (2014) Int J Neuropsychopharmacol , vol.17 , pp. 1487-1500
    • Park, H.G.1    Yu, H.S.2    Park, S.3    Ahn, Y.M.4    Kim, Y.S.5    Kim, S.H.6
  • 12
    • 83055180618 scopus 로고    scopus 로고
    • Increased expression of histone deacetylases 2 in temporal lobe epilepsy: a study of epileptic patients and rat models
    • Huang Y, Zhao F, Wang L, Yin H, Zhou C, Wang X. Increased expression of histone deacetylases 2 in temporal lobe epilepsy: a study of epileptic patients and rat models. Synapse (2012) 66:151-9. doi:10.1002/syn.20995
    • (2012) Synapse , vol.66 , pp. 151-159
    • Huang, Y.1    Zhao, F.2    Wang, L.3    Yin, H.4    Zhou, C.5    Wang, X.6
  • 13
    • 84873171161 scopus 로고    scopus 로고
    • Epigenetics and epilepsy
    • Roopra A, Dingledine R, Hsieh J. Epigenetics and epilepsy. Epilepsia (2012) 53(Suppl 9):2-10. doi:10.1111/epi.12030
    • (2012) Epilepsia , vol.53 , pp. 2-10
    • Roopra, A.1    Dingledine, R.2    Hsieh, J.3
  • 14
    • 84876665067 scopus 로고    scopus 로고
    • Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction
    • Goldberg EM, Coulter DA. Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction. Nat Rev Neurosci (2013) 14:337-49. doi:10.1038/nrn3482
    • (2013) Nat Rev Neurosci , vol.14 , pp. 337-349
    • Goldberg, E.M.1    Coulter, D.A.2
  • 15
    • 33845799903 scopus 로고    scopus 로고
    • Polycomb silencing mechanisms and the management of genomic programmes
    • Schwartz YB, Pirrotta V. Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet (2007) 8:9-22. doi:10.1038/nrg1981
    • (2007) Nat Rev Genet , vol.8 , pp. 9-22
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 16
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis EB. A gene complex controlling segmentation in Drosophila. Nature (1978) 276:565-70. doi:10.1038/276565a0
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 17
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, Tempst P, et al. Role of histone H3 lysine 27 methylation in polycomb-group silencing. Science (2002) 298:1039-43. doi:10.1126/science.1076997
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 18
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of polycomb gene silencing: knowns and unknowns
    • Simon JA, Kingston RE. Mechanisms of polycomb gene silencing: knowns and unknowns. Nat Rev Mol Cell Biol (2009) 10:697-708. doi:10.1038/nrm2763
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 19
    • 77957154350 scopus 로고    scopus 로고
    • Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins
    • Mills AA. Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat Rev Cancer (2010) 10:669-82. doi:10.1038/nrc2931
    • (2010) Nat Rev Cancer , vol.10 , pp. 669-682
    • Mills, A.A.1
  • 20
    • 77958605856 scopus 로고    scopus 로고
    • Epigenetic choreographers of neurogenesis in the adult mammalian brain
    • Ma DK, Marchetto MC, Guo JU, Ming G-L, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nat Neurosci (2010) 13:1338-44. doi:10.1038/nn.2672
    • (2010) Nat Neurosci , vol.13 , pp. 1338-1344
    • Ma, D.K.1    Marchetto, M.C.2    Guo, J.U.3    Ming, G.-L.4    Gage, F.H.5    Song, H.6
  • 21
    • 77957680712 scopus 로고    scopus 로고
    • Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
    • Pereira JD, Sansom SN, Smith J, Dobenecker M-W, Tarakhovsky A, Livesey FJ. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci U S A (2010) 107:15957-62. doi:10.1073/pnas.1002530107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15957-15962
    • Pereira, J.D.1    Sansom, S.N.2    Smith, J.3    Dobenecker, M.-W.4    Tarakhovsky, A.5    Livesey, F.J.6
  • 22
    • 84899479091 scopus 로고    scopus 로고
    • Ezh2 regulates adult hippocampal neurogenesis and memory
    • Zhang J, Ji F, Liu Y, Lei X, Li H, Ji G, et al. Ezh2 regulates adult hippocampal neurogenesis and memory. J Neurosci (2014) 34:5184-99. doi:10.1523/JNEUROSCI.4129-13.2014
    • (2014) J Neurosci , vol.34 , pp. 5184-5199
    • Zhang, J.1    Ji, F.2    Liu, Y.3    Lei, X.4    Li, H.5    Ji, G.6
  • 23
    • 84872123130 scopus 로고    scopus 로고
    • Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons
    • Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, et al. Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science (2013) 339:204-7. doi:10.1126/science.1229326
    • (2013) Science , vol.339 , pp. 204-207
    • Di Meglio, T.1    Kratochwil, C.F.2    Vilain, N.3    Loche, A.4    Vitobello, A.5    Yonehara, K.6
  • 24
    • 84897858451 scopus 로고    scopus 로고
    • Coordinated regulation of dendrite arborization by epigenetic factors CDYL and EZH2
    • Qi C, Liu S, Qin R, Zhang Y, Wang G, Shang Y, et al. Coordinated regulation of dendrite arborization by epigenetic factors CDYL and EZH2. J Neurosci (2014) 34:4494-508. doi:10.1523/JNEUROSCI.3647-13.2014
    • (2014) J Neurosci , vol.34 , pp. 4494-4508
    • Qi, C.1    Liu, S.2    Qin, R.3    Zhang, Y.4    Wang, G.5    Shang, Y.6
  • 25
    • 84907584810 scopus 로고    scopus 로고
    • Dopamine signaling leads to loss of polycomb repression and aberrant gene activation in experimental parkinsonism
    • Södersten E, Feyder M, Lerdrup M, Gomes A-L, Kryh H, Spigolon G, et al. Dopamine signaling leads to loss of polycomb repression and aberrant gene activation in experimental parkinsonism. PLoS Genet (2014) 10:e1004574. doi:10.1371/journal.pgen.1004574
    • (2014) PLoS Genet , vol.10
    • Södersten, E.1    Feyder, M.2    Lerdrup, M.3    Gomes, A.-L.4    Kryh, H.5    Spigolon, G.6
  • 26
    • 84907192030 scopus 로고    scopus 로고
    • Neuronal necrosis is regulated by a conserved chromatin-modifying cascade
    • Liu K, Ding L, Li Y, Yang H, Zhao C, Lei Y, et al. Neuronal necrosis is regulated by a conserved chromatin-modifying cascade. Proc Natl Acad Sci U S A (2014) 101:13960-5. doi:10.1073/pnas.1413644111
    • (2014) Proc Natl Acad Sci U S A , vol.101 , pp. 13960-13965
    • Liu, K.1    Ding, L.2    Li, Y.3    Yang, H.4    Zhao, C.5    Lei, Y.6
  • 27
    • 77952579908 scopus 로고    scopus 로고
    • Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance
    • Stapels M, Piper C, Yang T, Li M, Stowell C, Xiong ZG, et al. Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci Signal (2010) 3:ra15. doi:10.1126/scisignal.2000502
    • (2010) Sci Signal , vol.3 , pp. ra15
    • Stapels, M.1    Piper, C.2    Yang, T.3    Li, M.4    Stowell, C.5    Xiong, Z.G.6
  • 29
    • 56349130733 scopus 로고    scopus 로고
    • Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways
    • Jimenez-Mateos EM, Hatazaki S, Johnson MB, Bellver-Estelles C, Mouri G, Bonner C, et al. Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis (2008) 32:442-53. doi:10.1016/j.nbd.2008.08.008
    • (2008) Neurobiol Dis , vol.32 , pp. 442-453
    • Jimenez-Mateos, E.M.1    Hatazaki, S.2    Johnson, M.B.3    Bellver-Estelles, C.4    Mouri, G.5    Bonner, C.6
  • 30
    • 33745763116 scopus 로고    scopus 로고
    • Cerebral preconditioning and ischaemic tolerance
    • Gidday JM. Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci (2006) 7:437-48. doi:10.1038/nrn1927
    • (2006) Nat Rev Neurosci , vol.7 , pp. 437-448
    • Gidday, J.M.1
  • 31
    • 0035399856 scopus 로고    scopus 로고
    • Activation of the nuclear factor-kappaB is a key event in brain tolerance
    • Blondeau N, Widmann C, Lazdunski M, Heurteaux C. Activation of the nuclear factor-kappaB is a key event in brain tolerance. J Neurosci (2001) 21:4668-77.
    • (2001) J Neurosci , vol.21 , pp. 4668-4677
    • Blondeau, N.1    Widmann, C.2    Lazdunski, M.3    Heurteaux, C.4
  • 32
    • 0028026973 scopus 로고
    • Rapid and selective enhancement of DNA binding activity of the transcription factor AP1 by systemic administration of N-methyl-D-aspartate in murine hippocampus
    • Yoneda Y, Ogita K. Rapid and selective enhancement of DNA binding activity of the transcription factor AP1 by systemic administration of N-methyl-D-aspartate in murine hippocampus. Neurochem Int (1994) 25:263-71. doi:10.1016/0197-0186(94)90070-1
    • (1994) Neurochem Int , vol.25 , pp. 263-271
    • Yoneda, Y.1    Ogita, K.2
  • 33
    • 84863401564 scopus 로고    scopus 로고
    • Differential DNA methylation patterns define status epilepticus and epileptic tolerance
    • Miller-Delaney SFC, Das S, Sano T, Jimenez-Mateos EM, Bryan K, Buckley PG, et al. Differential DNA methylation patterns define status epilepticus and epileptic tolerance. J Neurosci (2012) 32:1577-88. doi:10.1523/JNEUROSCI.5180-11.2012
    • (2012) J Neurosci , vol.32 , pp. 1577-1588
    • Miller-Delaney, S.F.C.1    Das, S.2    Sano, T.3    Jimenez-Mateos, E.M.4    Bryan, K.5    Buckley, P.G.6
  • 34
    • 44449145323 scopus 로고    scopus 로고
    • Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice
    • Mouri G, Jimenez-Mateos E, Engel T, Dunleavy M, Hatazaki S, Paucard A, et al. Unilateral hippocampal CA3-predominant damage and short latency epileptogenesis after intra-amygdala microinjection of kainic acid in mice. Brain Res (2008) 1213:140-51. doi:10.1016/j.brainres.2008.03.061
    • (2008) Brain Res , vol.1213 , pp. 140-151
    • Mouri, G.1    Jimenez-Mateos, E.2    Engel, T.3    Dunleavy, M.4    Hatazaki, S.5    Paucard, A.6
  • 35
    • 1942457291 scopus 로고    scopus 로고
    • Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization
    • Lein ES, Zhao X, Gage FH. Defining a molecular atlas of the hippocampus using DNA microarrays and high-throughput in situ hybridization. J Neurosci (2004) 24:3879-89. doi:10.1523/JNEUROSCI.4710-03.2004
    • (2004) J Neurosci , vol.24 , pp. 3879-3889
    • Lein, E.S.1    Zhao, X.2    Gage, F.H.3
  • 36
    • 34248222814 scopus 로고    scopus 로고
    • Developmental regulation of Eed complex composition governs a switch in global histone modification in brain
    • Kim SY, Levenson JM, Korsmeyer S, Sweatt JD, Schumacher A. Developmental regulation of Eed complex composition governs a switch in global histone modification in brain. J Biol Chem (2007) 282:9962-72. doi:10.1074/jbc.M608722200
    • (2007) J Biol Chem , vol.282 , pp. 9962-9972
    • Kim, S.Y.1    Levenson, J.M.2    Korsmeyer, S.3    Sweatt, J.D.4    Schumacher, A.5
  • 37
    • 84857567368 scopus 로고    scopus 로고
    • Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons
    • Abdouh M, Chatoo W, El Hajjar J, David J, Ferreira J, Bernier G. Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons. PLoS One (2012) 7:e31870. doi:10.1371/journal.pone.0031870
    • (2012) PLoS One , vol.7
    • Abdouh, M.1    Chatoo, W.2    El Hajjar, J.3    David, J.4    Ferreira, J.5    Bernier, G.6
  • 38
    • 79953311668 scopus 로고    scopus 로고
    • Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells
    • Vandamme J, Völkel P, Rosnoblet C, Le Faou P, Angrand P-O. Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells. Mol Cell Proteomics (2011) 10:M110.002642. doi:10.1074/mcp.M110.002642
    • (2011) Mol Cell Proteomics , vol.10
    • Vandamme, J.1    Völkel, P.2    Rosnoblet, C.3    Le Faou, P.4    Angrand, P.-O.5
  • 39
    • 0346751061 scopus 로고    scopus 로고
    • Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy
    • Becker AJ, Chen J, Zien A, Sochivko D, Normann S, Schramm J, et al. Correlated stage- and subfield-associated hippocampal gene expression patterns in experimental and human temporal lobe epilepsy. Eur J Neurosci (2003) 18:2792-802. doi:10.1111/j.1460-9568.2003.02993.x
    • (2003) Eur J Neurosci , vol.18 , pp. 2792-2802
    • Becker, A.J.1    Chen, J.2    Zien, A.3    Sochivko, D.4    Normann, S.5    Schramm, J.6
  • 40
    • 33751099302 scopus 로고    scopus 로고
    • Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy
    • Gorter JA, van Vliet EA, Aronica E, Breit T, Rauwerda H, Lopes da Silva FH, et al. Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J Neurosci (2006) 26:11083-110. doi:10.1523/JNEUROSCI.2766-06.2006
    • (2006) J Neurosci , vol.26 , pp. 11083-11110
    • Gorter, J.A.1    van Vliet, E.A.2    Aronica, E.3    Breit, T.4    Rauwerda, H.5    Lopes da Silva, F.H.6
  • 41
    • 77956270890 scopus 로고    scopus 로고
    • Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats
    • Laurén HB, Lopez-Picon FR, Brandt AM, Rios-Rojas CJ, Holopainen IE. Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats. PLoS One (2010) 5:e10733. doi:10.1371/journal.pone.0010733
    • (2010) PLoS One , vol.5
    • Laurén, H.B.1    Lopez-Picon, F.R.2    Brandt, A.M.3    Rios-Rojas, C.J.4    Holopainen, I.E.5
  • 42
    • 0037444461 scopus 로고    scopus 로고
    • Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth
    • Elliott RC, Miles MF, Lowenstein DH. Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth. J Neurosci (2003) 23:2218-27.
    • (2003) J Neurosci , vol.23 , pp. 2218-2227
    • Elliott, R.C.1    Miles, M.F.2    Lowenstein, D.H.3
  • 43
    • 77956600971 scopus 로고    scopus 로고
    • DNA methylation and Yin Yang-1 repress adenosine A2A receptor levels in human brain
    • Buira SP, Dentesano G, Albasanz JL, Moreno J, Martín M, Ferrer I, et al. DNA methylation and Yin Yang-1 repress adenosine A2A receptor levels in human brain. J Neurochem (2010) 115:283-95. doi:10.1111/j.1471-4159.2010.06928.x
    • (2010) J Neurochem , vol.115 , pp. 283-295
    • Buira, S.P.1    Dentesano, G.2    Albasanz, J.L.3    Moreno, J.4    Martín, M.5    Ferrer, I.6
  • 44
    • 14644426499 scopus 로고    scopus 로고
    • Changes in DNA binding pattern of transcription factor YY1 in neuronal degeneration
    • Korhonen P, Kyrylenko S, Suuronen T, Salminen A. Changes in DNA binding pattern of transcription factor YY1 in neuronal degeneration. Neurosci Lett (2005) 377:121-4. doi:10.1016/j.neulet.2004.11.085
    • (2005) Neurosci Lett , vol.377 , pp. 121-124
    • Korhonen, P.1    Kyrylenko, S.2    Suuronen, T.3    Salminen, A.4
  • 45
    • 58049200139 scopus 로고    scopus 로고
    • Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons
    • Rylski M, Amborska R, Zybura K, Mioduszewska B, Michaluk P, Jaworski J, et al. Yin Yang 1 is a critical repressor of matrix metalloproteinase-9 expression in brain neurons. J Biol Chem (2008) 283:35140-53. doi:10.1074/jbc.M804540200
    • (2008) J Biol Chem , vol.283 , pp. 35140-35153
    • Rylski, M.1    Amborska, R.2    Zybura, K.3    Mioduszewska, B.4    Michaluk, P.5    Jaworski, J.6
  • 46
    • 79551476179 scopus 로고    scopus 로고
    • Sustained downregulation of YY1-associated protein-related protein gene expression in rat hippocampus induced by repeated electroconvulsive shock
    • Ohtomo T, Kanamatsu T, Fujita M, Takagi M, Yamada J. Sustained downregulation of YY1-associated protein-related protein gene expression in rat hippocampus induced by repeated electroconvulsive shock. Biol Pharm Bull (2011) 34:249-52. doi:10.1248/bpb.34.249
    • (2011) Biol Pharm Bull , vol.34 , pp. 249-252
    • Ohtomo, T.1    Kanamatsu, T.2    Fujita, M.3    Takagi, M.4    Yamada, J.5
  • 47
    • 45849121349 scopus 로고    scopus 로고
    • Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
    • Pallàs M, Pizarro JG, Gutierrez-Cuesta J, Crespo-Biel N, Alvira D, Tajes M, et al. Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience (2008) 154:1388-97. doi:10.1016/j.neuroscience.2008.04.065
    • (2008) Neuroscience , vol.154 , pp. 1388-1397
    • Pallàs, M.1    Pizarro, J.G.2    Gutierrez-Cuesta, J.3    Crespo-Biel, N.4    Alvira, D.5    Tajes, M.6
  • 48
    • 84880134465 scopus 로고    scopus 로고
    • Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus
    • Chung S, Kim HJ, Yoon IS, Kim HJ, Choi SH, Kim YS, et al. Electroconvulsive shock increases SIRT1 immunoreactivity in the mouse hippocampus and hypothalamus. J ECT (2013) 29:93-100. doi:10.1097/YCT.0b013e31827659f7
    • (2013) J ECT , vol.29 , pp. 93-100
    • Chung, S.1    Kim, H.J.2    Yoon, I.S.3    Kim, H.J.4    Choi, S.H.5    Kim, Y.S.6
  • 49
    • 84916207913 scopus 로고    scopus 로고
    • Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus
    • Wang SJ, Zhao XH, Chen W, Bo N, Wang XJ, Chi ZF, et al. Sirtuin 1 activation enhances the PGC-1α/mitochondrial antioxidant system pathway in status epilepticus. Mol Med Rep (2015) 11:521-6. doi:10.3892/mmr.2014.2724
    • (2015) Mol Med Rep , vol.11 , pp. 521-526
    • Wang, S.J.1    Zhao, X.H.2    Chen, W.3    Bo, N.4    Wang, X.J.5    Chi, Z.F.6
  • 50
    • 84881232015 scopus 로고    scopus 로고
    • Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
    • Calao M, Sekyere EO, Cui HJ, Cheung BB, Thomas WD, Keating J, et al. Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation. Oncogene (2013) 32:3616-26. doi:10.1038/onc.2012.368
    • (2013) Oncogene , vol.32 , pp. 3616-3626
    • Calao, M.1    Sekyere, E.O.2    Cui, H.J.3    Cheung, B.B.4    Thomas, W.D.5    Keating, J.6
  • 51
    • 84873120891 scopus 로고    scopus 로고
    • RNF2/Ring1b negatively regulates p53 expression in selective cancer cell types to promote tumor development
    • Su W-J, Fang J-S, Cheng F, Liu C, Zhou F, Zhang J. RNF2/Ring1b negatively regulates p53 expression in selective cancer cell types to promote tumor development. Proc Natl Acad Sci U S A (2013) 110:1720-5. doi:10.1073/pnas.1211604110
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 1720-1725
    • Su, W.-J.1    Fang, J.-S.2    Cheng, F.3    Liu, C.4    Zhou, F.5    Zhang, J.6
  • 52
    • 84899079791 scopus 로고    scopus 로고
    • Heterozygous knockout of the Bmi-1 gene causes an early onset of phenotypes associated with brain aging
    • Gu M, Shen L, Bai L, Gao J, Marshall C, Wu T, et al. Heterozygous knockout of the Bmi-1 gene causes an early onset of phenotypes associated with brain aging. Age (2014) 36:129-39. doi:10.1007/s11357-013-9552-9
    • (2014) Age , vol.36 , pp. 129-139
    • Gu, M.1    Shen, L.2    Bai, L.3    Gao, J.4    Marshall, C.5    Wu, T.6
  • 53
    • 62449117918 scopus 로고    scopus 로고
    • MiR-34 SIRT1 and p53: the feedback loop
    • Yamakuchi M, Lowenstein CJ. MiR-34, SIRT1 and p53: the feedback loop. Cell Cycle (2009) 8:712-5. doi:10.4161/cc.8.5.7753
    • (2009) Cell Cycle , vol.8 , pp. 712-715
    • Yamakuchi, M.1    Lowenstein, C.J.2
  • 54
    • 80053935847 scopus 로고    scopus 로고
    • Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage
    • Wu Z, Lee ST, Qiao Y, Li Z, Lee PL, Lee YJ, et al. Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage. Cell Death Differ (2011) 18:1771-9. doi:10.1038/cdd.2011.48
    • (2011) Cell Death Differ , vol.18 , pp. 1771-1779
    • Wu, Z.1    Lee, S.T.2    Qiao, Y.3    Li, Z.4    Lee, P.L.5    Lee, Y.J.6
  • 55
    • 84859260959 scopus 로고    scopus 로고
    • REST-mediated recruitment of polycomb repressor complexes in mammalian cells
    • Dietrich N, Lerdrup M, Landt E, Agrawal-Singh S, Bak M, Tommerup N, et al. REST-mediated recruitment of polycomb repressor complexes in mammalian cells. PLoS Genet (2012) 8:e1002494. doi:10.1371/journal.pgen.1002494
    • (2012) PLoS Genet , vol.8
    • Dietrich, N.1    Lerdrup, M.2    Landt, E.3    Agrawal-Singh, S.4    Bak, M.5    Tommerup, N.6
  • 56
    • 84871984418 scopus 로고    scopus 로고
    • Modeling of epigenome dynamics identifies transcription factors that mediate polycomb targeting
    • Arnold P, Schöler A, Pachkov M, Balwierz PJ, Jørgensen H, Stadler MB, et al. Modeling of epigenome dynamics identifies transcription factors that mediate polycomb targeting. Genome Res (2013) 23:60-73. doi:10.1101/gr.142661.112
    • (2013) Genome Res , vol.23 , pp. 60-73
    • Arnold, P.1    Schöler, A.2    Pachkov, M.3    Balwierz, P.J.4    Jørgensen, H.5    Stadler, M.B.6
  • 57
    • 84875248366 scopus 로고    scopus 로고
    • Neurogenesis and epilepsy
    • 4th ed. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Bethesda, MD: National Center for Biotechnology Information (US)
    • Parent JM, Kron MM. Neurogenesis and epilepsy. 4th ed. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. Bethesda, MD: National Center for Biotechnology Information (US) (2012). p. 506-13.
    • (2012) Jasper's Basic Mechanisms of the Epilepsies [Internet] , pp. 506-513
    • Parent, J.M.1    Kron, M.M.2
  • 58
    • 55449105221 scopus 로고    scopus 로고
    • Genome wide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
    • Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, et al. Genome wide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet (2008) 4:e1000242. doi:10.1371/journal.pgen.1000242
    • (2008) PLoS Genet , vol.4
    • Ku, M.1    Koche, R.P.2    Rheinbay, E.3    Mendenhall, E.M.4    Endoh, M.5    Mikkelsen, T.S.6
  • 59
    • 33746407708 scopus 로고    scopus 로고
    • Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
    • Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, Koseki H, et al. Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J (2006) 25:3110-22. doi:10.1038/sj.emboj.7601187
    • (2006) EMBO J , vol.25 , pp. 3110-3122
    • Schoeftner, S.1    Sengupta, A.K.2    Kubicek, S.3    Mechtler, K.4    Spahn, L.5    Koseki, H.6
  • 60
    • 79956157987 scopus 로고    scopus 로고
    • REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements
    • Ren X, Kerppola TK. REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elements. Mol Cell Biol (2011) 31:2100-10. doi:10.1128/MCB.05088-11
    • (2011) Mol Cell Biol , vol.31 , pp. 2100-2110
    • Ren, X.1    Kerppola, T.K.2
  • 62
    • 55949132133 scopus 로고    scopus 로고
    • Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms
    • Margueron R, Li G, Sarma K, Blais A, Zavadil J, Woodcock CL, et al. Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. Mol Cell (2008) 32:503-18. doi:10.1016/j.molcel.2008.11.004
    • (2008) Mol Cell , vol.32 , pp. 503-518
    • Margueron, R.1    Li, G.2    Sarma, K.3    Blais, A.4    Zavadil, J.5    Woodcock, C.L.6
  • 63
    • 55949124844 scopus 로고    scopus 로고
    • EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
    • Shen X, Liu Y, Hsu Y-J, Fujiwara Y, Kim J, Mao X, et al. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol Cell (2008) 32:491-502. doi:10.1016/j.molcel.2008.10.016
    • (2008) Mol Cell , vol.32 , pp. 491-502
    • Shen, X.1    Liu, Y.2    Hsu, Y.-J.3    Fujiwara, Y.4    Kim, J.5    Mao, X.6
  • 64
    • 79952220410 scopus 로고    scopus 로고
    • EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
    • Ezhkova E, Lien W-H, Stokes N, Pasolli HA, Silva JM, Fuchs E. EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev (2011) 25:485-98. doi:10.1101/gad.2019811
    • (2011) Genes Dev , vol.25 , pp. 485-498
    • Ezhkova, E.1    Lien, W.-H.2    Stokes, N.3    Pasolli, H.A.4    Silva, J.M.5    Fuchs, E.6
  • 65
    • 78751662908 scopus 로고    scopus 로고
    • The polycomb complex PRC2 and its mark in life
    • Margueron R, Reinberg D. The polycomb complex PRC2 and its mark in life. Nature (2011) 469:343-9. doi:10.1038/nature09784
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2


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