-
1
-
-
33746826011
-
JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions
-
Arbouzova N.I., Zeidler M.P. JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions. Development 2006, 133:2605-2616.
-
(2006)
Development
, vol.133
, pp. 2605-2616
-
-
Arbouzova, N.I.1
Zeidler, M.P.2
-
2
-
-
73449091872
-
Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice
-
Asp M.L., Tian M., Wendel A.A., Belury M.A. Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. Int. J. Cancer 2010, 126:756-763.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 756-763
-
-
Asp, M.L.1
Tian, M.2
Wendel, A.A.3
Belury, M.A.4
-
3
-
-
84899657374
-
IGF binding proteins in cancer: mechanistic and clinical insights
-
Baxter R.C. IGF binding proteins in cancer: mechanistic and clinical insights. Nat. Rev. Cancer 2014, 14:329-341.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 329-341
-
-
Baxter, R.C.1
-
4
-
-
80051585152
-
Animal models of the cancer anorexia-cachexia syndrome
-
Bennani-Baiti N., Walsh D. Animal models of the cancer anorexia-cachexia syndrome. Support. Care Cancer 2011, 19:1451-1463.
-
(2011)
Support. Care Cancer
, vol.19
, pp. 1451-1463
-
-
Bennani-Baiti, N.1
Walsh, D.2
-
5
-
-
4043170088
-
Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors
-
Bilder D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 2004, 18:1909-1925.
-
(2004)
Genes Dev.
, vol.18
, pp. 1909-1925
-
-
Bilder, D.1
-
6
-
-
84872094183
-
Cellular and molecular mechanisms of muscle atrophy
-
Bonaldo P., Sandri M. Cellular and molecular mechanisms of muscle atrophy. Dis. Model. Mech. 2013, 6:25-39.
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 25-39
-
-
Bonaldo, P.1
Sandri, M.2
-
7
-
-
0036484062
-
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions
-
Britton J.S., Lockwood W.K., Li L., Cohen S.M., Edgar B.A. Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev. Cell 2002, 2:239-249.
-
(2002)
Dev. Cell
, vol.2
, pp. 239-249
-
-
Britton, J.S.1
Lockwood, W.K.2
Li, L.3
Cohen, S.M.4
Edgar, B.A.5
-
8
-
-
0242641565
-
Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
-
Brumby A.M., Richardson H.E. scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 2003, 22:5769-5779.
-
(2003)
EMBO J.
, vol.22
, pp. 5769-5779
-
-
Brumby, A.M.1
Richardson, H.E.2
-
9
-
-
84925060962
-
The transcriptional response to tumorigenic polarity loss in Drosophila
-
Bunker B.D., Nellimoottil T.T., Boileau R.M., Classen A.K., Bilder D. The transcriptional response to tumorigenic polarity loss in Drosophila. eLife 2015, 4:03189.
-
(2015)
eLife
, vol.4
, pp. 03189
-
-
Bunker, B.D.1
Nellimoottil, T.T.2
Boileau, R.M.3
Classen, A.K.4
Bilder, D.5
-
10
-
-
67649878194
-
Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response
-
Charroux B., Royet J. Elimination of plasmatocytes by targeted apoptosis reveals their role in multiple aspects of the Drosophila immune response. Proc. Natl. Acad. Sci. USA 2009, 106:9797-9802.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9797-9802
-
-
Charroux, B.1
Royet, J.2
-
11
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark I.E., Dodson M.W., Jiang C., Cao J.H., Huh J.R., Seol J.H., Yoo S.J., Hay B.A., Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 2006, 441:1162-1166.
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
12
-
-
84860491077
-
Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing
-
Colombani J., Andersen D.S., Léopold P. Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing. Science 2012, 336:582-585.
-
(2012)
Science
, vol.336
, pp. 582-585
-
-
Colombani, J.1
Andersen, D.S.2
Léopold, P.3
-
13
-
-
77955966751
-
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter
-
Cordero J.B., Macagno J.P., Stefanatos R.K., Strathdee K.E., Cagan R.L., Vidal M. Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Dev. Cell 2010, 18:999-1011.
-
(2010)
Dev. Cell
, vol.18
, pp. 999-1011
-
-
Cordero, J.B.1
Macagno, J.P.2
Stefanatos, R.K.3
Strathdee, K.E.4
Cagan, R.L.5
Vidal, M.6
-
14
-
-
84861943484
-
Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
-
Dar A.C., Das T.K., Shokat K.M., Cagan R.L. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature 2012, 486:80-84.
-
(2012)
Nature
, vol.486
, pp. 80-84
-
-
Dar, A.C.1
Das, T.K.2
Shokat, K.M.3
Cagan, R.L.4
-
15
-
-
0017260831
-
Demonstration of sensory neurones in the ectopic cuticle of spineless-aristapedia, a homoeotic mutant of Drosophila
-
Deak I.I. Demonstration of sensory neurones in the ectopic cuticle of spineless-aristapedia, a homoeotic mutant of Drosophila. Nature 1976, 260:252-254.
-
(1976)
Nature
, vol.260
, pp. 252-254
-
-
Deak, I.I.1
-
16
-
-
78650918920
-
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
-
Demontis F., Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell 2010, 143:813-825.
-
(2010)
Cell
, vol.143
, pp. 813-825
-
-
Demontis, F.1
Perrimon, N.2
-
17
-
-
84888363022
-
Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models
-
Demontis F., Piccirillo R., Goldberg A.L., Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Dis. Model. Mech. 2013, 6:1339-1352.
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 1339-1352
-
-
Demontis, F.1
Piccirillo, R.2
Goldberg, A.L.3
Perrimon, N.4
-
18
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H., Dodson M.W., Huang H., Guo M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl. Acad. Sci. USA 2008, 105:14503-14508.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
19
-
-
33750023633
-
Aktand FOXO dysregulation contribute to infection-induced wasting in Drosophila
-
Dionne M.S., Pham L.N., Shirasu-Hiza M., Schneider D.S. Aktand FOXO dysregulation contribute to infection-induced wasting in Drosophila. Curr. Biol. 2006, 16:1977-1985.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1977-1985
-
-
Dionne, M.S.1
Pham, L.N.2
Shirasu-Hiza, M.3
Schneider, D.S.4
-
20
-
-
34548636132
-
Elucidation of a universal size-control mechanism in Drosophila and mammals
-
Dong J., Feldmann G., Huang J., Wu S., Zhang N., Comerford S.A., Gayyed M.F., Anders R.A., Maitra A., Pan D. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007, 130:1120-1133.
-
(2007)
Cell
, vol.130
, pp. 1120-1133
-
-
Dong, J.1
Feldmann, G.2
Huang, J.3
Wu, S.4
Zhang, N.5
Comerford, S.A.6
Gayyed, M.F.7
Anders, R.A.8
Maitra, A.9
Pan, D.10
-
21
-
-
0035281979
-
Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis
-
Drummond-Barbosa D., Spradling A.C. Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Dev. Biol. 2001, 231:265-278.
-
(2001)
Dev. Biol.
, vol.231
, pp. 265-278
-
-
Drummond-Barbosa, D.1
Spradling, A.C.2
-
22
-
-
0028674969
-
Regulation of feeding behavior in adult Drosophila melanogaster varies with feeding regime and nutritional state
-
Edgecomb R.S., Harth C.E., Schneiderman A.M. Regulation of feeding behavior in adult Drosophila melanogaster varies with feeding regime and nutritional state. J.Exp. Biol. 1994, 197:215-235.
-
(1994)
J.Exp. Biol.
, vol.197
, pp. 215-235
-
-
Edgecomb, R.S.1
Harth, C.E.2
Schneiderman, A.M.3
-
23
-
-
84871909004
-
The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man
-
Elsum I., Yates L., Humbert P.O., Richardson H.E. The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man. Essays Biochem. 2012, 53:141-168.
-
(2012)
Essays Biochem.
, vol.53
, pp. 141-168
-
-
Elsum, I.1
Yates, L.2
Humbert, P.O.3
Richardson, H.E.4
-
24
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany M.B., Bender W.W. A Drosophila model of Parkinson's disease. Nature 2000, 404:394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
25
-
-
84864646651
-
Cancer cachexia: mediators, signaling, and metabolic pathways
-
Fearon K.C.H., Glass D.J., Guttridge D.C. Cancer cachexia: mediators, signaling, and metabolic pathways. Cell Metab. 2012, 16:153-166.
-
(2012)
Cell Metab.
, vol.16
, pp. 153-166
-
-
Fearon, K.C.H.1
Glass, D.J.2
Guttridge, D.C.3
-
26
-
-
84873406669
-
Understanding the mechanisms and treatment options in cancer cachexia
-
Fearon K., Arends J., Baracos V. Understanding the mechanisms and treatment options in cancer cachexia. Nat. Rev. Clin. Oncol. 2013, 10:90-99.
-
(2013)
Nat. Rev. Clin. Oncol.
, vol.10
, pp. 90-99
-
-
Fearon, K.1
Arends, J.2
Baracos, V.3
-
27
-
-
84860487216
-
Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation
-
Garelli A., Gontijo A.M., Miguela V., Caparros E., Dominguez M. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Science 2012, 336:579-582.
-
(2012)
Science
, vol.336
, pp. 579-582
-
-
Garelli, A.1
Gontijo, A.M.2
Miguela, V.3
Caparros, E.4
Dominguez, M.5
-
28
-
-
84875412051
-
Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics
-
Gonzalez C. Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics. Nat. Rev. Cancer 2013, 13:172-183.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 172-183
-
-
Gonzalez, C.1
-
29
-
-
33846279755
-
Specialized hepatocyte-like cells regulate Drosophila lipid metabolism
-
Gutierrez E., Wiggins D., Fielding B., Gould A.P. Specialized hepatocyte-like cells regulate Drosophila lipid metabolism. Nature 2007, 445:275-280.
-
(2007)
Nature
, vol.445
, pp. 275-280
-
-
Gutierrez, E.1
Wiggins, D.2
Fielding, B.3
Gould, A.P.4
-
30
-
-
24944578683
-
Differenzierungsleistungen wiederholt fragmentierter Teilstücke männlicher Genitalscheiben von Drosophila melanogaster nach Kultur invivo [Differentiation services repeatedly fragmented pieces of male genital part of Drosophila melanogaster slices after culture invivo]
-
Hadorn E. Differenzierungsleistungen wiederholt fragmentierter Teilstücke männlicher Genitalscheiben von Drosophila melanogaster nach Kultur invivo [Differentiation services repeatedly fragmented pieces of male genital part of Drosophila melanogaster slices after culture invivo]. Dev. Biol. 1963, 7:617-629.
-
(1963)
Dev. Biol.
, vol.7
, pp. 617-629
-
-
Hadorn, E.1
-
32
-
-
42249108516
-
Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance
-
Honegger B., Galic M., Köhler K., Wittwer F., Brogiolo W., Hafen E., Stocker H. Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. J.Biol. 2008, 7:10.
-
(2008)
J.Biol.
, vol.7
, pp. 10
-
-
Honegger, B.1
Galic, M.2
Köhler, K.3
Wittwer, F.4
Brogiolo, W.5
Hafen, E.6
Stocker, H.7
-
33
-
-
84866540191
-
The role of insulin resistance in the development of muscle wasting during cancer cachexia
-
Honors M.A., Kinzig K.P. The role of insulin resistance in the development of muscle wasting during cancer cachexia. J.Cachexia Sarcopenia Muscle 2012, 3:5-11.
-
(2012)
J.Cachexia Sarcopenia Muscle
, vol.3
, pp. 5-11
-
-
Honors, M.A.1
Kinzig, K.P.2
-
34
-
-
34347207237
-
Prandiology of Drosophila and the CAFE assay
-
Ja W.W., Carvalho G.B., Mak E.M., de la Rosa N.N., Fang A.Y., Liong J.C., Brummel T., Benzer S. Prandiology of Drosophila and the CAFE assay. Proc. Natl. Acad. Sci. USA 2007, 104:8253-8256.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 8253-8256
-
-
Ja, W.W.1
Carvalho, G.B.2
Mak, E.M.3
de la Rosa, N.N.4
Fang, A.Y.5
Liong, J.C.6
Brummel, T.7
Benzer, S.8
-
35
-
-
0031964429
-
Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues
-
Karim F.D., Rubin G.M. Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development 1998, 125:1-9.
-
(1998)
Development
, vol.125
, pp. 1-9
-
-
Karim, F.D.1
Rubin, G.M.2
-
36
-
-
84926384423
-
Systemic organ wasting induced by localized expression of thesecreted insulin/IGF antagonist ImpL2
-
this issue
-
Kwon Y., Song W., Droujinine I.A., Hu Y., Asara J.M., Perrimon N. Systemic organ wasting induced by localized expression of thesecreted insulin/IGF antagonist ImpL2. Dev. Cell 2015, 33:36-46. this issue.
-
(2015)
Dev. Cell
, vol.33
, pp. 36-46
-
-
Kwon, Y.1
Song, W.2
Droujinine, I.A.3
Hu, Y.4
Asara, J.M.5
Perrimon, N.6
-
37
-
-
36049044765
-
Drosophila and the genetics of the internal milieu
-
Leopold P., Perrimon N. Drosophila and the genetics of the internal milieu. Nature 2007, 450:186-188.
-
(2007)
Nature
, vol.450
, pp. 186-188
-
-
Leopold, P.1
Perrimon, N.2
-
38
-
-
84872309064
-
A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila
-
Okamoto N., Nakamori R., Murai T., Yamauchi Y., Masuda A., Nishimura T. A secreted decoy of InR antagonizes insulin/IGF signaling to restrict body growth in Drosophila. Genes Dev. 2013, 27:87-97.
-
(2013)
Genes Dev.
, vol.27
, pp. 87-97
-
-
Okamoto, N.1
Nakamori, R.2
Murai, T.3
Yamauchi, Y.4
Masuda, A.5
Nishimura, T.6
-
39
-
-
0242666126
-
A genetic screen in Drosophila for metastatic behavior
-
Pagliarini R.A., Xu T. A genetic screen in Drosophila for metastatic behavior. Science 2003, 302:1227-1231.
-
(2003)
Science
, vol.302
, pp. 1227-1231
-
-
Pagliarini, R.A.1
Xu, T.2
-
40
-
-
77957883342
-
The hippo signaling pathway in development and cancer
-
Pan D. The hippo signaling pathway in development and cancer. Dev. Cell 2010, 19:491-505.
-
(2010)
Dev. Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
41
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J., Lee S.B., Lee S., Kim Y., Song S., Kim S., Bae E., Kim J., Shong M., Kim J.-M., Chung J. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 2006, 441:1157-1161.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.-M.10
Chung, J.11
-
42
-
-
60649118070
-
An innate immune response of blood cells to tumors and tissue damage in Drosophila
-
discussion 153
-
Pastor-Pareja J.C., Wu M., Xu T. An innate immune response of blood cells to tumors and tissue damage in Drosophila. Dis. Model. Mech. 2008, 1:144-154. discussion 153.
-
(2008)
Dis. Model. Mech.
, vol.1
, pp. 144-154
-
-
Pastor-Pareja, J.C.1
Wu, M.2
Xu, T.3
-
43
-
-
84901271886
-
Tissue design: how Drosophila tumors remodel their neighborhood
-
Patel P.H., Edgar B.A. Tissue design: how Drosophila tumors remodel their neighborhood. Semin. Cell Dev. Biol. 2014, 28:86-95.
-
(2014)
Semin. Cell Dev. Biol.
, vol.28
, pp. 86-95
-
-
Patel, P.H.1
Edgar, B.A.2
-
44
-
-
84866978180
-
Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion
-
Rajan A., Perrimon N. Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell 2012, 151:123-137.
-
(2012)
Cell
, vol.151
, pp. 123-137
-
-
Rajan, A.1
Perrimon, N.2
-
45
-
-
4344563878
-
Role and regulation of starvation-induced autophagy in the Drosophila fat body
-
Scott R.C., Schuldiner O., Neufeld T.P. Role and regulation of starvation-induced autophagy in the Drosophila fat body. Dev. Cell 2004, 7:167-178.
-
(2004)
Dev. Cell
, vol.7
, pp. 167-178
-
-
Scott, R.C.1
Schuldiner, O.2
Neufeld, T.P.3
-
46
-
-
0002031074
-
Developmental genetics of oogenesis
-
Cold Spring Harbor Press, M. Bate, A. Martinez-Arias (Eds.)
-
Spradling A.C. Developmental genetics of oogenesis. The Development of Drosophila melanogaster 1993, 1-70. Cold Spring Harbor Press. M. Bate, A. Martinez-Arias (Eds.).
-
(1993)
The Development of Drosophila melanogaster
, pp. 1-70
-
-
Spradling, A.C.1
-
47
-
-
0036830917
-
Cachexia in cancer patients
-
Tisdale M.J. Cachexia in cancer patients. Nat. Rev. Cancer 2002, 2:862-871.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 862-871
-
-
Tisdale, M.J.1
-
48
-
-
67649982995
-
Mechanisms of cancer cachexia
-
Tisdale M.J. Mechanisms of cancer cachexia. Physiol. Rev. 2009, 89:381-410.
-
(2009)
Physiol. Rev.
, vol.89
, pp. 381-410
-
-
Tisdale, M.J.1
-
49
-
-
80053321476
-
Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model
-
Willecke M., Toggweiler J., Basler K. Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene 2011, 30:4067-4074.
-
(2011)
Oncogene
, vol.30
, pp. 4067-4074
-
-
Willecke, M.1
Toggweiler, J.2
Basler, K.3
-
50
-
-
0031893101
-
Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes
-
Woodhouse E., Hersperger E., Shearn A. Growth, metastasis, and invasiveness of Drosophila tumors caused by mutations in specific tumor suppressor genes. Dev. Genes Evol. 1998, 207:542-550.
-
(1998)
Dev. Genes Evol.
, vol.207
, pp. 542-550
-
-
Woodhouse, E.1
Hersperger, E.2
Shearn, A.3
|