An innate immune response of blood cells to tumors and tissue damage in Drosophila

DMM Disease Models and Mechanisms

Volumn 1, Issue 2-3, 2008, Pages 144-154

  Pastor Pareja, José Carlos ^a   Ming, Wu ^a   Tian, Xu ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GELATINASE A; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; BLOOD CELL; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; DROSOPHILA MELANOGASTER; HUMAN; IMMUNE SYSTEM; INNATE IMMUNITY; MEMBRANE DAMAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE INJURY; TUMOR IMMUNITY; VERTEBRATE; WOUND; ANIMAL; EXPERIMENTAL NEOPLASM; IMMUNOLOGY; PATHOLOGY;

ANIMALIA; DROSOPHILA MELANOGASTER; MUS; VERTEBRATA;

ANIMALS; CELL ADHESION; DROSOPHILA MELANOGASTER; HEMOCYTES; IMMUNITY, INNATE; NEOPLASMS, EXPERIMENTAL;

EID: 60649118070     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.000950     Document Type: Article

References (58)

1. Adachi-Yamada, T., Fujimura-Kamada, K., Nishida, Y. and Matsumoto, K. (1999). Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing. Nature 400, 166-169. (Pubitemid 29327545)
2. Agaisse, H., Petersen, U. M., Boutros, M., Mathey-Prevot, B. and Perrimon, N. (2003). Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev. Cell 5, 441-450. (Pubitemid 37107673)
3. Balkwill, F. and Mantovani, A. (2001). Inflammation and cancer: back to Virchow? Lancet 357, 539-545. (Pubitemid 32173595)
4. Bilder, D. and Perrimon, N. (2000). Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 403, 676-680. (Pubitemid 30104011)
5. Boon, T., Cerottini, J. C., Van den Eynde, B., van der Bruggen, P. and Van Pel, A. (1994). Tumor antigens recognized by T lymphocytes. Annu. Rev. Immunol. 12, 337-365.
6. Bosch, M., Serras, F., Martin-Blanco, E. and Baguna, J. (2005). JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs. Dev. Biol. 280, 73-86. (Pubitemid 40342743)
7. Brennan, C. A. and Anderson, K. V. (2004). Drosophila: the genetics of innate immune recognition and response. Annu. Rev. Immunol. 22, 457-483. (Pubitemid 38680430)
8. Brown, S., Hu, N. and Hombria, J. C. (2001). Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless. Curr. Biol. 11, 1700-1705. (Pubitemid 33037783)
9. Chang, H. Y., Nuyten, D. S., Sneddon, J. B., Hastie, T., Tibshirani, R., Sorlie, T., Dai, H., He, Y. D., van't Veer, L. J., Bartelink, H. et al. (2005). Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc. Natl. Acad. Sci. USA 102, 3738-3743.
10. Chao, J. L., Tsai, Y. C., Chiu, S. J. and Sun, Y. H. (2004). Localized Notch signal acts through eyg and upd to promote global growth in Drosophila eye. Development 131, 3839-3847.
11. de Visser, K. E., Eichten, A. and Coussens, L. M. (2006). Paradoxical roles of the immune system during cancer development. Nat. Rev. Cancer 6, 24-37. (Pubitemid 43053650)
12. Dunn, G. P., Bruce, A. T., Ikeda, H., Old, L. J. and Schreiber, R. D. (2002). Cancer immunoediting: from immunosurveillance to tumor escape. Nat. Immunol. 3, 991-998. (Pubitemid 35363648)
13. Dvorak, H. F. (1986). Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. Engl. J. Med. 315, 1650-1659.
14. Ekas, L. A., Baeg, G. H., Flaherty, M. S., Ayala-Camargo, A. and Bach, E. A. (2006). JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133, 4721-4729. (Pubitemid 46063084)
15. Evans, C. J., Hartenstein, V. and Banerjee, U. (2003). Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev. Cell 5, 673-690. (Pubitemid 37362212)
16. Fessler, J. H. and Fessler, L. I. (1989). Drosophila extracellular matrix. Annu. Rev. Cell Biol. 5, 309-339.
17. Garen, A., Kauvar, L. and Lepesant, J. A. (1977). Roles of ecdysone in Drosophila development. Proc. Natl. Acad. Sci. USA 74, 5099-5103.
18. Girardi, M., Oppenheim, D. E., Steele, C. R., Lewis, J. M., Glusac, E., Filler, R., Hobby, P., Sutton, B., Tigelaar, R. E. and Hayday, A. C. (2001). Regulation of cutaneous malignancy by gamma delta T cells. Science 294, 605-609. (Pubitemid 32999559)
19. Glise, B., Bourbon, H. and Noselli, S. (1995). hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement. Cell 83, 451-461.
20. Harrison, D. A., Binari, R., Nahreini, T. S., Gilman, M. and Perrimon, N. (1995). Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J. 14, 2857-2865.
21. Harshbarger, J. C. and Taylor, R. L. (1968). Neoplasms of insects. Annu. Rev. Entomol. 13, 159-190.
22. Hartenstein, V. (2006). Blood cells and blood cell development in the animal kingdom. Annu. Rev. Cell Dev. Biol. 22, 677-712. (Pubitemid 44778012)
23. Hoffmann, J. A., Kafatos, F. C., Janeway, C. A. and Ezekowitz, R. A. (1999). Phylogenetic perspectives in innate immunity. Science 284, 1313-1318.
24. Holz, A., Bossinger, B., Strasser, T., Janning, W. and Klapper, R. (2003). The two origins of hemocytes in Drosophila. Development 130, 4955-4962.
25. Hombria, J. C. and Brown, S. (2002). The fertile field of Drosophila Jak/STAT signalling. Curr. Biol. 12, R569-R575.
26. Igaki, T., Pagliarini, R. A. and Xu, T. (2006). Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. Curr. Biol. 16, 1139-1146. (Pubitemid 43815753)
27. Janeway, C. A., Jr (1989). Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54 Pt 1, 1-13.
28. Kurucz, E., Markus, R., Zsamboki, J., Folkl-Medzihradszky, K., Darula, Z., Vilmos, P., Udvardy, A., Krausz, I., Lukacsovich, T., Gateff, E. et al. (2007). Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes. Curr. Biol. 17, 649-654. (Pubitemid 46509583)
29. Lebestky, T., Chang, T., Hartenstein, V. and Banerjee, U. (2000). Specification of Drosophila hematopoietic lineage by conserved transcription factors. Science 288, 146-149. (Pubitemid 30203049)
30. Lemaitre, B. and Hoffmann, J. (2007). The host defense of Drosophila melanogaster. Annu. Rev. Immunol. 25, 697-743.
31. Llano, E., Adam, G., Pendas, A. M., Quesada, V., Sanchez, L. M., Santamaria, I., Noselli, S. and Lopez-Otin, C. (2002). Structural and enzymatic characterization of Drosophila Dm2-MMP, a membrane-bound matrix metalloproteinase with tissue-specific expression. J. Biol. Chem. 277, 23321-23329. (Pubitemid 34952162)
32. Martin-Blanco, E., Gampel, A., Ring, J., Virdee, K., Kirov, N., Tolkovsky, A. M. and Martinez-Arias, A. (1998). puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev. 12, 557-570. (Pubitemid 28101018)
33. Matzinger, P. (1994). Tolerance, Danger, and the Extended Family. Annu. Rev. Immunol. 12, 991-1045.
34. Matzinger, P. (2002). The danger model: a renewed sense of self. Science 296, 301-305.
35. Meister, M. and Lagueux, M. (2003). Drosophila blood cells. Cell Microbiol. 5, 573-580.
36. Moreno, E., Basler, K. and Morata, G. (2002). Cells compete for Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature 416, 755-759. (Pubitemid 34429153)
37. Morin, X., Daneman, R., Zavortink, M. and Chia, W. (2001). A protein trap strategy to detect GFP-tagged proteins expressed from their endogenous loci in Drosophila. Proc. Natl. Acad. Sci. USA 98, 15050-15055. (Pubitemid 34013967)
38. Mott, J. D. and Werb, Z. (2004). Regulation of matrix biology by matrix metalloproteinases. Curr. Opin. Cell Biol. 16, 558-564.
39. Ogura, Y., Sutterwala, F. S. and Flavell, R. A. (2006). The inflammasome: first line of the immune response to cell stress. Cell 126, 659-662. (Pubitemid 44233635)
40. Page-McCaw, A., Serano, J., Sante, J. M. and Rubin, G. M. (2003). Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development. Dev. Cell 4, 95-106. (Pubitemid 36105336)
41. Pagliarini, R. A. and Xu, T. (2003). A genetic screen in Drosophila for metastatic behavior. Science 302, 1227-1231.
42. Pastor-Pareja, J. C., Grawe, F., Martín-Blanco, E. and García-Bellido, A. (2004). Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade. Dev. Cell 7, 387-399. (Pubitemid 39232974)
43. Pham, L. N., Dionne, M. S., Shirasu-Hiza, M. and Schneider, D. S. (2007). A specific primed immune response in Drosophila is dependent on phagocytes. PLoS Pathog. 3, e26. (Pubitemid 46535803)
44. Ramet, M., Lanot, R., Zachary, D. and Manfruelli, P. (2002). JNK signaling pathway is required for efficient wound healing in Drosophila. Dev. Biol. 241, 145-156. (Pubitemid 34066768)
45. Rizki, R. M. and Rizki, T. M. (1980). Hemocyte responses to implanted tissues in Drosophila melanogaster larvae. Dev. Genes Evol. 189, 207-213.
46. Ryoo, H. D., Gorenc, T. and Steller, H. (2004). Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev. Cell 7, 491-501. (Pubitemid 39341835)
47. Scharrer, B. and Lochhead, M. S. (1950). Tumors in the invertebrates: a review. Cancer Res. 10, 403-419.
48. Shi, Y., Evans, J. E. and Rock, K. L. (2003). Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425, 516-521. (Pubitemid 37237047)
49. Smyth, M. J., Thia, K. Y., Street, S. E., Cretney, E., Trapani, J. A., Taniguchi, M., Kawano, T., Pelikan, S. B., Crowe, N. Y. and Godfrey, D. I. (2000). Differential tumor surveillance by natural killer (NK) and NKT cells. J. Exp. Med. 191, 661-668. (Pubitemid 30691419)
50. Srivastava, A., Pastor-Pareja, J. C., Igaki, T., Pagliarini, R. and Xu, T. (2007). Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proc. Natl. Acad. Sci. USA 104, 2721-2726. (Pubitemid 46327946)
51. Stronach, B. E. and Perrimon, N. (1999). Stress signaling in Drosophila. Oncogene 18, 6172-6182.
52. Tepass, U., Fessler, L. I., Aziz, A. and Hartenstein, V. (1994). Embryonic origin of hemocytes and their relationship to cell death in Drosophila. Development 120, 1829-1837. (Pubitemid 24209717)
53. Uhlirova, M. and Bohmann, D. (2006). JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J. 25, 5294-5304. (Pubitemid 44764139)
54. Vilmos, P., Nagy, I., Kurucz, E., Hultmark, D., Gateff, E. and Ando, I. (2004). A rapid rosetting method for separation of hemocyte sub-populations of Drosophila melanogaster. Dev. Comp. Immunol. 28, 555-563. (Pubitemid 38210281)
55. Weston, C. R. and Davis, R. J. (2007). The JNK signal transduction pathway. Curr. Opin. Cell Biol. 19, 142-149.
56. Wood, W., Faria, C. and Jacinto, A. (2006). Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. J. Cell Biol. 173, 405-416.
57. Zettervall, C. J., Anderl, I., Williams, M. J., Palmer, R., Kurucz, E., Ando, I. and Hultmark, D. (2004). A directed screen for genes involved in Drosophila blood cell activation. Proc. Natl. Acad. Sci. USA 101, 14192-14197. (Pubitemid 39305052)
58. Zhou, L., Schnitzler, A., Agapite, J., Schwartz, L. M., Steller, H. and Nambu, J. R. (1997). Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells. Proc. Natl. Acad. Sci. USA 94, 5131-5136. (Pubitemid 27214748)