Regulatory T cells produce profibrotic cytokines in the skin of patients with systemic sclerosis

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 4, 2015, Pages 946-955.e9

  Macdonald, Katherine G ^a   Dawson, Nicholas A J ^a   Huang, Qing ^b   Dunne, James V ^b,c   Levings, Megan K ^a   Broady, Raewyn ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

forkhead box protein 3; human; IL 13; IL 33; IL 33 receptor fibroblasts; IL 4; Regulatory T cells; skin fibrosis; ST2; systemic sclerosis TH2 cells; T cell plasticity

Indexed keywords

CHEMOKINE RECEPTOR; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 4; TRANSCRIPTION FACTOR FOXP3; CELL SURFACE RECEPTOR; IL1RL1 PROTEIN, HUMAN;

ADULT; ARTICLE; AUTOIMMUNITY; BLOOD; CELL DIFFERENTIATION; CELL FUNCTION; CELL TRANSDIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PUNCH BIOPSY; REGULATORY T LYMPHOCYTE; SKIN BIOPSY; SKIN FIBROSIS; SYSTEMIC SCLEROSIS; TH2 CELL; DRUG EFFECTS; FIBROSIS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PATHOLOGY; SKIN; T LYMPHOCYTE SUBPOPULATION;

CYTOKINES; FIBROSIS; GENE EXPRESSION; HUMANS; INTERLEUKIN-13; LYMPHOCYTE COUNT; RECEPTORS, CELL SURFACE; RECEPTORS, CHEMOKINE; SCLERODERMA, SYSTEMIC; SKIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 84926249566     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.12.1932     Document Type: Article

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