-
1
-
-
82555196095
-
Systemic lupus erythematosus
-
Tsokos GC. Systemic lupus erythematosus. N Engl J Med 2011;365:2110-21.
-
(2011)
N Engl J Med
, vol.365
, pp. 2110-2121
-
-
Tsokos, G.C.1
-
2
-
-
84859416933
-
Regulatory T cells: Mechanisms of differentiation and function
-
Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol 2012;30:531-64.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
3
-
-
77957801548
-
Pathogenetic aspects of systemic lupus erythematosus with an emphasis on regulatory T cells
-
Scheinecker C, Bonelli M, Smolen JS. Pathogenetic aspects of systemic lupus erythematosus with an emphasis on regulatory T cells. J Autoimmun 2010;35:269-75.
-
(2010)
J Autoimmun
, vol.35
, pp. 269-275
-
-
Scheinecker, C.1
Bonelli, M.2
Smolen, J.S.3
-
4
-
-
33846900430
-
high T regulatory cell function in patients with active systemic lupus erythematosus
-
Valencia X, Yarboro C, Illei G, et al. Deficient CD4+CD25 high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 2007;178:2579-88. (Pubitemid 46233461)
-
(2007)
Journal of Immunology
, vol.178
, Issue.4
, pp. 2579-2588
-
-
Valencia, X.1
Yarboro, C.2
Illei, G.3
Lipsky, P.E.4
-
6
-
-
42449123048
-
+ T cells of patients with systemic lupus erythematosus: A comparative phenotypic analysis
-
DOI 10.1136/ard.2007.074690
-
Bonelli M, von DK, Savitskaya A, et al. Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus: a comparative phenotypic analysis. Ann Rheum Dis 2008;67:664-71. (Pubitemid 351571931)
-
(2008)
Annals of the Rheumatic Diseases
, vol.67
, Issue.5
, pp. 664-671
-
-
Bonelli, M.1
Von Dalwigk, K.2
Savitskaya, A.3
Smolen, J.S.4
Scheinecker, C.5
-
7
-
-
0242403301
-
Quantification of regulatory T cells in patients with systemic lupus erythematosus
-
DOI 10.1016/S0896-8411(03)00121-5
-
Crispin JC, Martinez A, Alcocer-Varela J. Quantification of regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2003;21:273-6. (Pubitemid 37410115)
-
(2003)
Journal of Autoimmunity
, vol.21
, Issue.3
, pp. 273-276
-
-
Crispin, J.C.1
Martinez, A.2
Alcocer-Varela, J.3
-
8
-
-
45849145442
-
Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)
-
DOI 10.1093/intimm/dxn044
-
Bonelli M, Savitskaya A, von DK, et al. Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE). Int Immunol 2008;20:861-8. (Pubitemid 351876312)
-
(2008)
International Immunology
, vol.20
, Issue.7
, pp. 861-868
-
-
Bonelli, M.1
Savitskaya, A.2
Von Dalwigk, K.3
Steiner, C.W.4
Aletaha, D.5
Smolen, J.S.6
Scheinecker, C.7
-
9
-
-
81755184312
-
Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis
-
Chavele KM, Ehrenstein MR. Regulatory T-cells in systemic lupus erythematosus and rheumatoid arthritis. FEBS Lett 2011;585:3603-10.
-
(2011)
FEBS Lett
, vol.585
, pp. 3603-3610
-
-
Chavele, K.M.1
Ehrenstein, M.R.2
-
10
-
-
29144516273
-
Global natural regulatory T cell depletion in active systemic lupus erythematosus
-
Miyara M, Amoura Z, Parizot C, et al. Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol 2005;175:8392-400. (Pubitemid 41798406)
-
(2005)
Journal of Immunology
, vol.175
, Issue.12
, pp. 8392-8400
-
-
Miyara, M.1
Amoura, Z.2
Parizot, C.3
Badoual, C.4
Dorgham, K.5
Trad, S.6
Nochy, D.7
Debre, P.8
Piette, J.-C.9
Gorochov, G.10
-
11
-
-
33947121146
-
Transient regulatory T-cells: A state attained by all activated human T-cells
-
DOI 10.1016/j.clim.2006.10.014, PII S1521661606009405
-
Pillai V, Ortega SB, Wang CK, et al. Transient regulatory T-cells: a state attained by all activated human T-cells. Clin Immunol 2007;123:18-29. (Pubitemid 46401504)
-
(2007)
Clinical Immunology
, vol.123
, Issue.1
, pp. 18-29
-
-
Pillai, V.1
Ortega, S.B.2
Wang, C.K.3
Karandikar, N.J.4
-
12
-
-
33646240855
-
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
-
Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 2006;103:6659-64.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6659-6664
-
-
Gavin, M.A.1
Torgerson, T.R.2
Houston, E.3
-
13
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor Foxp3
-
DOI 10.1016/j.immuni.2005.01.016
-
Fontenot JD, Rasmussen JP, Williams LM, et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005;22:329-41. (Pubitemid 40387475)
-
(2005)
Immunity
, vol.22
, Issue.3
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
14
-
-
36048978911
-
Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature
-
DOI 10.1016/j.immuni.2007.09.010, PII S107476130700492X
-
Hill JA, Feuerer M, Tash K, et al. Foxp3 transcription-factor-dependent and-independent regulation of the regulatory T cell transcriptional signature. Immunity 2007;27:786-800. (Pubitemid 350110546)
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
Haxhinasto, S.4
Perez, J.5
Melamed, R.6
Mathis, D.7
Benoist, C.8
-
15
-
-
77951638740
-
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3 + T regulatory cells
-
Thornton AM, Korty PE, Tran DQ, et al. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3 + T regulatory cells. J Immunol 2010;184:3433-41.
-
(2010)
J Immunol
, vol.184
, pp. 3433-3441
-
-
Thornton, A.M.1
Korty, P.E.2
Tran, D.Q.3
-
16
-
-
78650636296
-
Comment on "expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3 + T regulatory cells"
-
Verhagen J, Wraith DC. Comment on "Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3 + T regulatory cells". J Immunol 2010;185:7129.
-
(2010)
J Immunol
, vol.185
, pp. 7129
-
-
Verhagen, J.1
Wraith, D.C.2
-
17
-
-
80052287274
-
Helios expression is a marker of T cell activation and proliferation
-
Akimova T, Beier UH, Wang L, et al. Helios expression is a marker of T cell activation and proliferation. PLoS One 2011;6:e24226.
-
(2011)
PLoS One
, vol.6
-
-
Akimova, T.1
Beier, U.H.2
Wang, L.3
-
18
-
-
84856567623
-
Expression of Helios in peripherally induced Foxp3+ regulatory T cells
-
Gottschalk RA, Corse E, Allison JP. Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J Immunol 2012;188:976-80.
-
(2012)
J Immunol
, vol.188
, pp. 976-980
-
-
Gottschalk, R.A.1
Corse, E.2
Allison, J.P.3
-
19
-
-
77950628840
-
A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells
-
Getnet D, Grosso JF, Goldberg MV, et al. A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Mol Immunol 2010;47:1595-600.
-
(2010)
Mol Immunol
, vol.47
, pp. 1595-1600
-
-
Getnet, D.1
Grosso, J.F.2
Goldberg, M.V.3
-
20
-
-
84859123340
-
Phenotypic and functional properties of helios(+) regulatory T cells
-
Zabransky DJ, Nirschl CJ, Durham NM, et al. Phenotypic and functional properties of helios(+) regulatory T cells. PLoS One 2012;7:e34547.
-
(2012)
PLoS One
, vol.7
-
-
Zabransky, D.J.1
Nirschl, C.J.2
Durham, N.M.3
-
21
-
-
84863360489
-
Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion
-
Published Online First: 31 Jan. doi: 10.1182/blood-2011-09-377895
-
Kim YC, Bhairavabhotla R, Yoon J, et al. Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion. Blood Published Online First: 31 Jan 2012. doi: 10.1182/blood-2011-09-377895
-
(2012)
Blood
-
-
Kim, Y.C.1
Bhairavabhotla, R.2
Yoon, J.3
-
22
-
-
59449092041
-
Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system
-
Alexander T, Thiel A, Rosen O, et al. Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood 2009;113:214-23.
-
(2009)
Blood
, vol.113
, pp. 214-223
-
-
Alexander, T.1
Thiel, A.2
Rosen, O.3
-
23
-
-
40549111926
-
Direct assessment of thymic reactivation after autologous stem cell transplantation
-
DOI 10.1159/000117824
-
Thiel A, Alexander T, Schmidt CA, et al. Direct assessment of thymic reactivation after autologous stem cell transplantation. Acta Haematol 2008;119:22-7. (Pubitemid 351363854)
-
(2008)
Acta Haematologica
, vol.119
, Issue.1
, pp. 22-27
-
-
Thiel, A.1
Alexander, T.2
Schmidt, C.A.3
Przybylski, G.K.4
Kimmig, S.5
Kohler, S.6
Radtke, H.7
Gromnica-Ihle, E.8
Massenkeil, G.9
Radbruch, A.10
Arnold, R.11
Hiepe, F.12
-
24
-
-
46249105330
-
Single-cell phospho-protein analysis by flow cytometry
-
doi: 10.1002/0471142735. im0817s96
-
Schulz KR, Danna EA, Krutzik PO, et al. Single-cell phospho-protein analysis by flow cytometry. Curr Protoc Immunol 2012;96:8.17.1-8.17.20. doi: 10.1002/0471142735. im0817s96
-
(2012)
Curr Protoc Immunol
, vol.96
, pp. 1-20
-
-
Schulz, K.R.1
Danna, E.A.2
Krutzik, P.O.3
-
25
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
-
26
-
-
33745817085
-
+ T reg cells
-
DOI 10.1084/jem.20060772
-
Liu W, Putnam AL, Xu-Yu Z, et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006;203:1701-11. (Pubitemid 44036276)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.7
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
De St. Groth, B.F.10
Clayberger, C.11
Soper, D.M.12
Ziegler, S.F.13
Bluestone, J.A.14
-
27
-
-
66949171924
-
Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
-
Miyara M, Yoshioka Y, Kitoh A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 2009;30:899-911.
-
(2009)
Immunity
, vol.30
, pp. 899-911
-
-
Miyara, M.1
Yoshioka, Y.2
Kitoh, A.3
-
28
-
-
69949133380
-
CXCR3, inflammation, and autoimmune diseases
-
Lacotte S, Brun S, Muller S, et al. CXCR3, inflammation, and autoimmune diseases. Ann NY Acad Sci 2009;1173:310-17.
-
(2009)
Ann NY Acad Sci
, vol.1173
, pp. 310-317
-
-
Lacotte, S.1
Brun, S.2
Muller, S.3
-
29
-
-
33947254437
-
Cutting edge: Chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4 T cells under physiological conditions
-
Campbell JJ, O'Connell DJ, Wurbel MA. Cutting Edge: chemokine receptor CCR4 is necessary for antigen-driven cutaneous accumulation of CD4T cells under physiological conditions. J Immunol 2007;178:3358-62. (Pubitemid 46417598)
-
(2007)
Journal of Immunology
, vol.178
, Issue.6
, pp. 3358-3362
-
-
Campbell, J.J.1
O'Connell, D.J.2
Wurbel, M.-A.3
-
30
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S, Freyer J, Siewert C, et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007;5:e38.
-
(2007)
PLoS Biol
, vol.5
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
-
31
-
-
0037128660
-
Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
-
DOI 10.1084/jem.20011756
-
Kimmig S, Przybylski GK, Schmidt CA, et al. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J Exp Med 2002;195:789-94. (Pubitemid 34259723)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.6
, pp. 789-794
-
-
Kimmig, S.1
Przybylski, G.K.2
Schmidt, C.A.3
Laurisch, K.4
Mowes, B.5
Radbruch, A.6
Thiel, A.7
-
32
-
-
77952754636
-
Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO
-
Booth NJ, McQuaid AJ, Sobande T, et al. Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO. J Immunol 2010;184:4317-26.
-
(2010)
J Immunol
, vol.184
, pp. 4317-4326
-
-
Booth, N.J.1
McQuaid, A.J.2
Sobande, T.3
-
33
-
-
67649876115
-
New insights into the regulation of T cells by gamma(c) family cytokines
-
Rochman Y, Spolski R, Leonard WJ. New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol 2009;9:480-90.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 480-490
-
-
Rochman, Y.1
Spolski, R.2
Leonard, W.J.3
-
34
-
-
79960657991
-
Multidimensional single cell based STAT phosphorylation profiling identifies a novel biosignature for evaluation of systemic lupus erythematosus activity
-
Huang X, Guo Y, Bao C, et al. Multidimensional single cell based STAT phosphorylation profiling identifies a novel biosignature for evaluation of systemic lupus erythematosus activity. PLoS One 2011;6:e21671.
-
(2011)
PLoS One
, vol.6
-
-
Huang, X.1
Guo, Y.2
Bao, C.3
-
35
-
-
4143066714
-
+ T cell receptors
-
DOI 10.1016/j.immuni.2004.07.009, PII S1074761304001979
-
Hsieh CS, Liang Y, Tyznik AJ, et al. Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity 2004;21:267-77. (Pubitemid 39094055)
-
(2004)
Immunity
, vol.21
, Issue.2
, pp. 267-277
-
-
Hsieh, C.-S.1
Liang, Y.2
Tyznik, A.J.3
Self, S.G.4
Liggitt, D.5
Rudensky, A.Y.6
-
36
-
-
33747099523
-
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells
-
Pacholczyk R, Ignatowicz H, Kraj P, et al. Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity 2006;25:249-59.
-
(2006)
Immunity
, vol.25
, pp. 249-259
-
-
Pacholczyk, R.1
Ignatowicz, H.2
Kraj, P.3
-
37
-
-
74049164847
-
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
-
Wing K, Sakaguchi S. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol 2010;11:7-13.
-
(2010)
Nat Immunol
, vol.11
, pp. 7-13
-
-
Wing, K.1
Sakaguchi, S.2
-
38
-
-
58249117641
-
CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients
-
Enghard P, Humrich JY, Rudolph B, et al. CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients. Arthritis Rheum 2009;60:199-206.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 199-206
-
-
Enghard, P.1
Humrich, J.Y.2
Rudolph, B.3
-
39
-
-
84865352053
-
Peripherally Circulating CD4(+) FOXP3(+) CXCR3(+) T regulatory cells correlate with renal allograft function
-
Hoerning A, Kohler S, Jun C, et al. Peripherally Circulating CD4(+) FOXP3(+) CXCR3(+) T regulatory cells correlate with renal allograft function. Scand J Immunol 2012;76:320-8.
-
(2012)
Scand J Immunol
, vol.76
, pp. 320-328
-
-
Hoerning, A.1
Kohler, S.2
Jun, C.3
-
40
-
-
80051801789
-
Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs
-
Elkord E, Sharma S, Burt DJ, et al. Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced Tregs. Clin Immunol 2011;140:218-22.
-
(2011)
Clin Immunol
, vol.140
, pp. 218-222
-
-
Elkord, E.1
Sharma, S.2
Burt, D.J.3
-
41
-
-
76249100290
-
Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus
-
Humrich JY, Morbach H, Undeutsch R, et al. Homeostatic imbalance of regulatory and effector T cells due to IL-2 deprivation amplifies murine lupus. Proc Natl Acad Sci USA 2010;107:204-9.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 204-209
-
-
Humrich, J.Y.1
Morbach, H.2
Undeutsch, R.3
-
42
-
-
78149360607
-
Autoimmunity and chronic inflammation-two clearance-related steps in the etiopathogenesis of SLE
-
Munoz LE, Janko C, Schulze C, et al. Autoimmunity and chronic inflammation-two clearance-related steps in the etiopathogenesis of SLE. Autoimmun Rev 2010;10:38-42.
-
(2010)
Autoimmun Rev
, vol.10
, pp. 38-42
-
-
Munoz, L.E.1
Janko, C.2
Schulze, C.3
-
43
-
-
63149094153
-
Phenotypic and functional analysis of CD4+
-
Bonelli M, Savitskaya A, Steiner CW, et al. Phenotypic and functional analysis of CD4+. J Immunol 2009;182:1689-95.
-
(2009)
J Immunol
, vol.182
, pp. 1689-1695
-
-
Bonelli, M.1
Savitskaya, A.2
Steiner, C.W.3
|