메뉴 건너뛰기




Volumn 71, Issue 7, 2012, Pages 1227-1234

Activated and resting regulatory T cell exhaustion concurs with high levels of interleukin-22 expression in systemic sclerosis lesions

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 22; TRANSCRIPTION FACTOR FOXP3;

EID: 84862565756     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-200709     Document Type: Article
Times cited : (91)

References (45)
  • 1
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: A prototypic multisystem fibrotic disorder
    • DOI 10.1172/JCI31139
    • Varga J, Abraham D. Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 2007;117:557-67. (Pubitemid 46348510)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 3
    • 33745277147 scopus 로고    scopus 로고
    • Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis
    • Baroni SS, Santillo M, Bevilacqua F, et al. Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. N Engl J Med 2006;354:2667-76.
    • (2006) N Engl J Med , vol.354 , pp. 2667-2676
    • Baroni, S.S.1    Santillo, M.2    Bevilacqua, F.3
  • 4
    • 0025173841 scopus 로고
    • Increase in activated T cells and reduction in suppressor inducer T cells in systemic sclerosis
    • Gustafsson R, Tötterman TH, Klareskog L, et al. Increase in activated T cells and reduction in suppressor inducer T cells in systemic sclerosis. Ann Rheum Dis 1990;49:40-5.
    • (1990) Ann Rheum Dis , vol.49 , pp. 40-45
    • Gustafsson, R.1    Tötterman, T.H.2    Klareskog, L.3
  • 7
    • 0021154318 scopus 로고
    • Lymphocytes in the skin of patients with progressive systemic sclerosis: Quantification, subtyping, and clinical correlations
    • Roumm AD, Whiteside TL, Medsger TA Jr, et al. Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations. Arthritis Rheum 1984;27:645-53. (Pubitemid 14089474)
    • (1984) Arthritis and Rheumatism , vol.27 , Issue.6 , pp. 645-653
    • Roumm, A.D.1    Whiteside, T.L.2    Medsger Jr., T.A.3    Rodnan, G.P.4
  • 8
    • 72949097179 scopus 로고    scopus 로고
    • Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis
    • Meloni F, Solari N, Cavagna L, et al. Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis. Clin Exp Rheumatol 2009;27:765-72.
    • (2009) Clin Exp Rheumatol , vol.27 , pp. 765-772
    • Meloni, F.1    Solari, N.2    Cavagna, L.3
  • 9
    • 0033000530 scopus 로고    scopus 로고
    • Production of type 2, cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis
    • DOI 10.1002/1529-0131(199906)42:6<1168::AID-ANR13>3.0.CO;2-L
    • Atamas SP, Yurovsky VV, Wise R, et al. Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis. Arthritis Rheum 1999;42:1168-78. (Pubitemid 29268953)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.6 , pp. 1168-1178
    • Atamas, S.P.1    Yurovsky, V.V.2    Wise, R.3    Wigley, F.M.4    Goter, R.C.J.5    Henry, P.6    Alms, W.J.7    White, B.8
  • 11
    • 33646240855 scopus 로고    scopus 로고
    • Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
    • Gavin MA, Torgerson TR, Houston E, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 2006;103:6659-64.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6659-6664
    • Gavin, M.A.1    Torgerson, T.R.2    Houston, E.3
  • 12
    • 35448930435 scopus 로고    scopus 로고
    • - T cells by T-cell receptor stimulation is transforming growth factor-beta-dependent but does not confer a regulatory phenotype
    • DOI 10.1182/blood-2007-06-094656
    • Tran DQ, Ramsey H, Shevach EM. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 2007;110:2983-90. (Pubitemid 350006952)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 14
    • 66949171924 scopus 로고    scopus 로고
    • Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
    • Miyara M, Yoshioka Y, Kitoh A, et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 2009;30:899-911.
    • (2009) Immunity , vol.30 , pp. 899-911
    • Miyara, M.1    Yoshioka, Y.2    Kitoh, A.3
  • 16
    • 12444279957 scopus 로고    scopus 로고
    • Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}
    • Rao PE, Petrone AL, Ponath PD. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. J Immunol 2005;174:1446-55.
    • (2005) J Immunol , vol.174 , pp. 1446-1455
    • Rao, P.E.1    Petrone, A.L.2    Ponath, P.D.3
  • 18
    • 36549048990 scopus 로고    scopus 로고
    • H17 in the pathogenesis of systemic scleroderma
    • DOI 10.1038/ncprheum0618, PII NCPRHEUM0618
    • Deleuran B, Abraham DJ. Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma. Nat Clin Pract Rheumatol 2007;3:682-3. (Pubitemid 350187010)
    • (2007) Nature Clinical Practice Rheumatology , vol.3 , Issue.12 , pp. 682-683
    • Deleuran, B.1    Abraham, D.J.2
  • 19
    • 79959798607 scopus 로고    scopus 로고
    • Reduction of regulatory T cells in skin lesions but not in peripheral blood of patients with systemic scleroderma
    • Klein S, Kretz CC, Ruland V, et al. Reduction of regulatory T cells in skin lesions but not in peripheral blood of patients with systemic scleroderma. Ann Rheum Dis 2011;70:1475-81.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1475-1481
    • Klein, S.1    Kretz, C.C.2    Ruland, V.3
  • 20
    • 67650128154 scopus 로고    scopus 로고
    • Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression
    • Radstake TR, van Bon L, Broen J, et al. Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression. PLoS ONE 2009;4:e5981.
    • (2009) PLoS ONE , vol.4
    • Radstake, T.R.1    Van Bon, L.2    Broen, J.3
  • 21
    • 77649178968 scopus 로고    scopus 로고
    • Regulatory T cells (CD4(+)CD25(bright) FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity
    • Slobodin G, Ahmad MS, Rosner I, et al. Regulatory T cells (CD4(+)CD25(bright) FoxP3(+)) expansion in systemic sclerosis correlates with disease activity and severity. Cell Immunol 2010;261:77-80.
    • (2010) Cell Immunol , vol.261 , pp. 77-80
    • Slobodin, G.1    Ahmad, M.S.2    Rosner, I.3
  • 22
    • 77956619921 scopus 로고    scopus 로고
    • Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis. Correlations with disease severity and phenotypes
    • Giovannetti A, Rosato E, Renzi C, et al. Analyses of T cell phenotype and function reveal an altered T cell homeostasis in systemic sclerosis. Correlations with disease severity and phenotypes. Clin Immunol 2010;137:122-33.
    • (2010) Clin Immunol , vol.137 , pp. 122-133
    • Giovannetti, A.1    Rosato, E.2    Renzi, C.3
  • 23
    • 0033758344 scopus 로고    scopus 로고
    • Increased interleukin-17 production in patients with systemic sclerosis
    • Kurasawa K, Hirose K, Sano H, et al. Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum 2000;43:2455-63.
    • (2000) Arthritis Rheum , vol.43 , pp. 2455-2463
    • Kurasawa, K.1    Hirose, K.2    Sano, H.3
  • 24
    • 42649134787 scopus 로고    scopus 로고
    • Clinical association of serum interleukin-17 levels in systemic sclerosis: Is systemic sclerosis a Th17 disease?
    • Murata M, Fujimoto M, Matsushita T, et al. Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease? J Dermatol Sci 2008;50:240-2.
    • (2008) J Dermatol Sci , vol.50 , pp. 240-242
    • Murata, M.1    Fujimoto, M.2    Matsushita, T.3
  • 25
    • 67650114978 scopus 로고    scopus 로고
    • The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes
    • Radstake TR, van Bon L, Broen J, et al. The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenotypes. PLoS ONE 2009;4:e5903.
    • (2009) PLoS ONE , vol.4
    • Radstake, T.R.1    Van Bon, L.2    Broen, J.3
  • 26
    • 80053911955 scopus 로고    scopus 로고
    • Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: Association with interstitial lung disease
    • Truchetet ME, Brembilla NC, Montanari E, et al. Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease. Arthritis Res Ther 2011;13:R166.
    • (2011) Arthritis Res Ther , vol.13
    • Truchetet, M.E.1    Brembilla, N.C.2    Montanari, E.3
  • 28
    • 0029048089 scopus 로고
    • Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis
    • Clements P, Lachenbruch P, Siebold J, et al. Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis. J Rheumatol 1995;22:1281-5.
    • (1995) J Rheumatol , vol.22 , pp. 1281-1285
    • Clements, P.1    Lachenbruch, P.2    Siebold, J.3
  • 30
    • 0033767899 scopus 로고    scopus 로고
    • Severe organ involvement in systemic sclerosis with diffuse scleroderma
    • Steen VD, Medsger TA Jr. Severe organ involvement in systemic sclerosis with diffuse scleroderma. Arthritis Rheum 2000;43:2437-44.
    • (2000) Arthritis Rheum , vol.43 , pp. 2437-2444
    • Steen, V.D.1    Medsger Jr., T.A.2
  • 33
    • 79955618079 scopus 로고    scopus 로고
    • Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis
    • Papp G, Horvath IF, Barath S, et al. Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis. Scand J Rheumatol 2011;40:205-10.
    • (2011) Scand J Rheumatol , vol.40 , pp. 205-210
    • Papp, G.1    Horvath, I.F.2    Barath, S.3
  • 34
    • 79955974107 scopus 로고    scopus 로고
    • Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis
    • Fenoglio D, Battaglia F, Parodi A, et al. Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis. Clin Immunol 2011;139:249-57.
    • (2011) Clin Immunol , vol.139 , pp. 249-257
    • Fenoglio, D.1    Battaglia, F.2    Parodi, A.3
  • 39
    • 79952584368 scopus 로고    scopus 로고
    • Recent advances in IL-22 biology
    • Zenewicz LA, Flavell RA. Recent advances in IL-22 biology. Int Immunol 2011;23:159-63.
    • (2011) Int Immunol , vol.23 , pp. 159-163
    • Zenewicz, L.A.1    Flavell, R.A.2
  • 40
    • 67349195975 scopus 로고    scopus 로고
    • IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not
    • Wolk K, Haugen HS, Xu W, et al. IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not. J Mol Med 2009;87:523-36.
    • (2009) J Mol Med , vol.87 , pp. 523-536
    • Wolk, K.1    Haugen, H.S.2    Xu, W.3
  • 41
    • 56649111439 scopus 로고    scopus 로고
    • Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer
    • Aden N, Shiwen X, Aden D, et al. Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer. Rheumatology (Oxford) 2008;47:1754-60.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 1754-1760
    • Aden, N.1    Shiwen, X.2    Aden, D.3
  • 42
    • 79953329144 scopus 로고    scopus 로고
    • Histopathological cutaneous alterations in systemic sclerosis: A clinicopathological study
    • Van Praet JT, Smith V, Haspeslagh M, et al. Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study. Arthritis Res Ther 2011;13:R35.
    • (2011) Arthritis Res Ther , vol.13
    • Van Praet, J.T.1    Smith, V.2    Haspeslagh, M.3
  • 43
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • Trifari S, Kaplan CD, Tran EH, et al. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol 2009;10:864-71.
    • (2009) Nat Immunol , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3
  • 44
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen T, Geiger R, Jarrossay D, et al. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol 2009;10:857-63.
    • (2009) Nat Immunol , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.