Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: Role of p62/sequestosome 1 as a signaling hub

Cellular Physiology and Biochemistry

Volumn 35, Issue 5, 2015, Pages 1773-1786

  Li, Guangbi ^a   Li, Cai Xia ^a   Xia, Min ^a   Ritter, Joseph K ^a   Gehr, Todd W B ^a   Boini, Krishna ^a   Li, Pin Lan ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Glomerulosclerosis; Lysosomal enzymes; Podocyte transdifferentiation; Selective autophagy; Ubiquitin binding protein

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BAFILOMYCIN; CALVASCULIN; CYCLIN DEPENDENT KINASE 1; P CADHERIN; PROTEIN P62; PROTEIN ZO1; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SMALL INTERFERING RNA; SPAUDIN 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTIN; BAFILOMYCIN A; CADHERIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROLIDE; NFE2L2 PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN; TJP1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; LIGHT CHAIN; MITOSIS; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; HUMAN; LYSOSOME; METABOLISM;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CADHERINS; CDC2 PROTEIN KINASE; CELL DIFFERENTIATION; CELL LINE; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; LYSOSOMES; MACROLIDES; MICROSCOPY, CONFOCAL; MITOSIS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; PODOCYTES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VACUOLAR PROTON-TRANSLOCATING ATPASES; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84926229056     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000373989     Document Type: Article

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