MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits

Molecular Therapy

Volumn 22, Issue 10, 2014, Pages 1829-1838

  Vinciguerra, Antonio ^a   Formisano, Luigi ^a,b   Cerullo, Pierpaolo ^a   Guida, Natascia ^a   Cuomo, Ornella ^a   Esposito, Alba ^a   Di Renzo, Gianfranco ^a   Annunziato, Lucio ^a,c   Pignataro, Giuseppe ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

^c IRCCS SDN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI MICRORNA 103 1; MESSENGER RNA; MICRORNA; MICRORNA 103 1; NEUROPROTECTIVE AGENT; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM CALCIUM EXCHANGER 1; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ANTISENSE OLIGONUCLEOTIDE; MIRN103 MICRORNA, HUMAN; SODIUM-CALCIUM EXCHANGER 1;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BHK CELL LINE; BRAIN CELL; BRAIN CORTEX; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; EMBRYO; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PC12 CELL LINE; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; BINDING SITE; BRAIN; CELL LINE; CEREBROVASCULAR ACCIDENT; CHEMISTRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; NERVE CELL; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY; RNA INTERFERENCE;

RATTUS;

3' UNTRANSLATED REGIONS; ANIMALS; BASE SEQUENCE; BINDING SITES; BRAIN; BRAIN ISCHEMIA; CELL LINE; CEREBRAL CORTEX; CORPUS STRIATUM; CRICETINAE; DOWN-REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; MALE; MICRORNAS; NEURONS; OLIGORIBONUCLEOTIDES, ANTISENSE; RATS; RNA INTERFERENCE; SODIUM-CALCIUM EXCHANGER; STROKE; TRANSFECTION;

EID: 84926227278     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2014.113     Document Type: Article

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