A new concept: A/β 1-42 generates a hyper functional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death

Journal of Neuroscience

Volumn 32, Issue 31, 2012, Pages 10609-10617

  Pannaccione, Anna ^a   Secondo, Agnese ^a   Molinaro, Pasquale ^a   D'Avanzo, Carla ^a   Cantile, Maria ^a   Esposito, Alba ^a   Boscia, Francesca ^a   Scorziello, Antonella ^a   Sirabella, Rossana ^b   Di Renzo, Gianfranco ^a   Annunziato, Lucio ^a,b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b IRCCS SDN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN [1-42]; CALPAIN; CALPEPTIN; CASPASE 12; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; ENDOPLASMIC RETICULUM; FEMALE; GENE SILENCING; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STAINING; WESTERN BLOTTING;

AMYLOID BETA-PEPTIDES; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALPAIN; CASPASE 3; CELL DEATH; CELL DIFFERENTIATION; CELLS, CULTURED; CHELATING AGENTS; CRICETINAE; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; EMBRYO, MAMMALIAN; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FEMALE; HIPPOCAMPUS; MALE; MICE; MICE, KNOCKOUT; NERVE GROWTH FACTOR; NEURONS; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PROTEOLYSIS; RATS; RNA INTERFERENCE; SODIUM; SODIUM-CALCIUM EXCHANGER; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84864443107     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.6429-11.2012     Document Type: Article

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