메뉴 건너뛰기




Volumn 73, Issue 9, 2013, Pages 915-923

Ghrelin signaling in the ventral hippocampus stimulates learned and motivational aspects of feeding via PI3K-Akt signaling

Author keywords

Dopamine; GHSR; learning; memory; nucleus accumbens; obesity; reward

Indexed keywords

GHRELIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SUCROSE;

EID: 84876295102     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.07.002     Document Type: Article
Times cited : (158)

References (77)
  • 1
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • M. Tschop, D.L. Smiley, and M.L. Heiman Ghrelin induces adiposity in rodents Nature 407 2000 908 913
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 2
    • 79952483790 scopus 로고    scopus 로고
    • Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice
    • J.F. Davis, D.L. Choi, D.J. Clegg, and S.C. Benoit Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice Physiol Behav 103 2011 39 43
    • (2011) Physiol Behav , vol.103 , pp. 39-43
    • Davis, J.F.1    Choi, D.L.2    Clegg, D.J.3    Benoit, S.C.4
  • 6
    • 0038660489 scopus 로고    scopus 로고
    • Ghrelin in hypothalamic regulation of energy balance
    • T.L. Horvath, S. Diano, and M. Tschop Ghrelin in hypothalamic regulation of energy balance Curr Top Med Chem 3 2003 921 927
    • (2003) Curr Top Med Chem , vol.3 , pp. 921-927
    • Horvath, T.L.1    Diano, S.2    Tschop, M.3
  • 7
    • 0037456519 scopus 로고    scopus 로고
    • The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
    • M.A. Cowley, R.G. Smith, S. Diano, M. Tschop, N. Pronchuk, and K.L. Grove The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis Neuron 37 2003 649 661
    • (2003) Neuron , vol.37 , pp. 649-661
    • Cowley, M.A.1    Smith, R.G.2    Diano, S.3    Tschop, M.4    Pronchuk, N.5    Grove, K.L.6
  • 9
    • 46349086081 scopus 로고    scopus 로고
    • Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus
    • L.F. Faulconbridge, H.J. Grill, J.M. Kaplan, and D. Daniels Caudal brainstem delivery of ghrelin induces fos expression in the nucleus of the solitary tract, but not in the arcuate or paraventricular nuclei of the hypothalamus Brain Res 1218 2008 151 157
    • (2008) Brain Res , vol.1218 , pp. 151-157
    • Faulconbridge, L.F.1    Grill, H.J.2    Kaplan, J.M.3    Daniels, D.4
  • 10
    • 84255177234 scopus 로고    scopus 로고
    • Role of ghrelin in food reward: Impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression
    • K.P. Skibicka, C. Hansson, E. Egecioglu, and S.L. Dickson Role of ghrelin in food reward: Impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression Addict Biol 17 2012 95 107
    • (2012) Addict Biol , vol.17 , pp. 95-107
    • Skibicka, K.P.1    Hansson, C.2    Egecioglu, E.3    Dickson, S.L.4
  • 12
    • 33748560432 scopus 로고    scopus 로고
    • Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite
    • A. Abizaid, Z.W. Liu, Z.B. Andrews, M. Shanabrough, E. Borok, and J.D. Elsworth Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite J Clin Invest 116 2006 3229 3239
    • (2006) J Clin Invest , vol.116 , pp. 3229-3239
    • Abizaid, A.1    Liu, Z.W.2    Andrews, Z.B.3    Shanabrough, M.4    Borok, E.5    Elsworth, J.D.6
  • 13
    • 27744593324 scopus 로고    scopus 로고
    • Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens
    • A.M. Naleid, M.K. Grace, D.E. Cummings, and A.S. Levine Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens Peptides 26 2005 2274 2279
    • (2005) Peptides , vol.26 , pp. 2274-2279
    • Naleid, A.M.1    Grace, M.K.2    Cummings, D.E.3    Levine, A.S.4
  • 14
    • 0030762351 scopus 로고    scopus 로고
    • Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues
    • X. Guan, H. Yu, O. Palyha, K. McKee, S. Feighner, and D. Sirinathsinghji Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues Brain Res Mol Brain Res 48 1997 23 29
    • (1997) Brain Res Mol Brain Res , vol.48 , pp. 23-29
    • Guan, X.1    Yu, H.2    Palyha, O.3    McKee, K.4    Feighner, S.5    Sirinathsinghji, D.6
  • 17
    • 0347064001 scopus 로고    scopus 로고
    • Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin
    • V.P. Carlini, M.M. Varas, A.B. Cragnolini, H.B. Schioth, T.N. Scimonelli, and S.R. de Barioglio Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin Biochem Biophys Res Commun 313 2004 635 641
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 635-641
    • Carlini, V.P.1    Varas, M.M.2    Cragnolini, A.B.3    Schioth, H.B.4    Scimonelli, T.N.5    De Barioglio, S.R.6
  • 18
    • 5344232095 scopus 로고    scopus 로고
    • Hippocampus: Cognitive processes and neural representations that underlie declarative memory
    • H. Eichenbaum Hippocampus: Cognitive processes and neural representations that underlie declarative memory Neuron 44 2004 109 120
    • (2004) Neuron , vol.44 , pp. 109-120
    • Eichenbaum, H.1
  • 21
    • 84860471766 scopus 로고    scopus 로고
    • Cognitive and neuronal systems underlying obesity
    • S.E. Kanoski Cognitive and neuronal systems underlying obesity Physiol Behav 106 2012 337 344
    • (2012) Physiol Behav , vol.106 , pp. 337-344
    • Kanoski, S.E.1
  • 22
    • 79952483902 scopus 로고    scopus 로고
    • Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity
    • S.E. Kanoski, and T.L. Davidson Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity Physiol Behav 103 2011 59 68
    • (2011) Physiol Behav , vol.103 , pp. 59-68
    • Kanoski, S.E.1    Davidson, T.L.2
  • 23
    • 33744903965 scopus 로고    scopus 로고
    • Analysis of direct hippocampal cortical field CA1 axonal projections to diencephalon in the rat
    • L.A. Cenquizca, and L.W. Swanson Analysis of direct hippocampal cortical field CA1 axonal projections to diencephalon in the rat J Comp Neurol 497 2006 101 114
    • (2006) J Comp Neurol , vol.497 , pp. 101-114
    • Cenquizca, L.A.1    Swanson, L.W.2
  • 24
    • 62149109664 scopus 로고    scopus 로고
    • Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation
    • T.L. Davidson, K. Chan, L.E. Jarrard, S.E. Kanoski, D.J. Clegg, and S.C. Benoit Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation Hippocampus 19 2009 235 252
    • (2009) Hippocampus , vol.19 , pp. 235-252
    • Davidson, T.L.1    Chan, K.2    Jarrard, L.E.3    Kanoski, S.E.4    Clegg, D.J.5    Benoit, S.C.6
  • 26
    • 0023241467 scopus 로고
    • Organization of the projections from the subiculum to the ventral striatum in the rat A study using anterograde transport of Phaseolus vulgaris leucoagglutinin
    • H.J. Groenewegen, E. Vermeulen-Van der Zee, A. te Kortschot, and M.P. Witter Organization of the projections from the subiculum to the ventral striatum in the rat A study using anterograde transport of Phaseolus vulgaris leucoagglutinin Neuroscience 23 1987 103 120
    • (1987) Neuroscience , vol.23 , pp. 103-120
    • Groenewegen, H.J.1    Vermeulen-Van Der Zee, E.2    Te Kortschot, A.3    Witter, M.P.4
  • 27
    • 0019906110 scopus 로고
    • The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde- and retrograde-horseradish peroxidase study
    • A.E. Kelley, and V.B. Domesick The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde- and retrograde-horseradish peroxidase study Neuroscience 7 1982 2321 2335
    • (1982) Neuroscience , vol.7 , pp. 2321-2335
    • Kelley, A.E.1    Domesick, V.B.2
  • 28
    • 79955576847 scopus 로고    scopus 로고
    • Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats
    • S.E. McCallum, O.D. Taraschenko, E.R. Hathaway, M.Y. Vincent, and S.D. Glick Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats Psychopharmacology (Berl) 215 2011 247 256
    • (2011) Psychopharmacology (Berl) , vol.215 , pp. 247-256
    • McCallum, S.E.1    Taraschenko, O.D.2    Hathaway, E.R.3    Vincent, M.Y.4    Glick, S.D.5
  • 29
    • 78651424438 scopus 로고    scopus 로고
    • Local infusion of ghrelin enhanced hippocampal synaptic plasticity and spatial memory through activation of phosphoinositide 3-kinase in the dentate gyrus of adult rats
    • L. Chen, T. Xing, M. Wang, Y. Miao, M. Tang, and J. Chen Local infusion of ghrelin enhanced hippocampal synaptic plasticity and spatial memory through activation of phosphoinositide 3-kinase in the dentate gyrus of adult rats Eur J Neurosci 33 2011 266 275
    • (2011) Eur J Neurosci , vol.33 , pp. 266-275
    • Chen, L.1    Xing, T.2    Wang, M.3    Miao, Y.4    Tang, M.5    Chen, J.6
  • 30
    • 53349175016 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells
    • H. Chung, S. Seo, M. Moon, and S. Park Phosphatidylinositol-3-kinase/Akt/ glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells J Endocrinol 198 2008 511 521
    • (2008) J Endocrinol , vol.198 , pp. 511-521
    • Chung, H.1    Seo, S.2    Moon, M.3    Park, S.4
  • 31
    • 66149185377 scopus 로고    scopus 로고
    • Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance
    • M.R. Hayes, K.P. Skibicka, K.K. Bence, and H.J. Grill Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance Endocrinology 150 2009 2175 2182
    • (2009) Endocrinology , vol.150 , pp. 2175-2182
    • Hayes, M.R.1    Skibicka, K.P.2    Bence, K.K.3    Grill, H.J.4
  • 32
    • 0019794835 scopus 로고
    • Glucoreceptors controlling feeding and blood glucose: Location in the hindbrain
    • R.C. Ritter, P.G. Slusser, and S. Stone Glucoreceptors controlling feeding and blood glucose: Location in the hindbrain Science 213 1981 451 452
    • (1981) Science , vol.213 , pp. 451-452
    • Ritter, R.C.1    Slusser, P.G.2    Stone, S.3
  • 33
    • 1842484296 scopus 로고    scopus 로고
    • AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    • Y. Minokoshi, T. Alquier, N. Furukawa, Y.B. Kim, A. Lee, and B. Xue AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus Nature 428 2004 569 574
    • (2004) Nature , vol.428 , pp. 569-574
    • Minokoshi, Y.1    Alquier, T.2    Furukawa, N.3    Kim, Y.B.4    Lee, A.5    Xue, B.6
  • 34
    • 34447253015 scopus 로고    scopus 로고
    • The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat
    • S.E. Kanoski, R.L. Meisel, A.J. Mullins, and T.L. Davidson The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat Behav Brain Res 182 2007 57 66
    • (2007) Behav Brain Res , vol.182 , pp. 57-66
    • Kanoski, S.E.1    Meisel, R.L.2    Mullins, A.J.3    Davidson, T.L.4
  • 35
    • 72649103549 scopus 로고    scopus 로고
    • Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation
    • M.R. Hayes, K.P. Skibicka, T.M. Leichner, D.J. Guarnieri, R.J. DiLeone, and K.K. Bence Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation Cell Metab 11 2010 77 83
    • (2010) Cell Metab , vol.11 , pp. 77-83
    • Hayes, M.R.1    Skibicka, K.P.2    Leichner, T.M.3    Guarnieri, D.J.4    Dileone, R.J.5    Bence, K.K.6
  • 37
    • 0036854550 scopus 로고    scopus 로고
    • Central melanocortin receptor agonist reduces spontaneous and scheduled meal size but does not augment duodenal preload-induced feeding inhibition
    • A.V. Azzara, J.P. Sokolnicki, and G.J. Schwartz Central melanocortin receptor agonist reduces spontaneous and scheduled meal size but does not augment duodenal preload-induced feeding inhibition Physiol Behav 77 2002 411 416
    • (2002) Physiol Behav , vol.77 , pp. 411-416
    • Azzara, A.V.1    Sokolnicki, J.P.2    Schwartz, G.J.3
  • 39
    • 0021147642 scopus 로고
    • Meal initiation controlled by learned cues: Basic behavioral properties
    • H.P. Weingarten Meal initiation controlled by learned cues: Basic behavioral properties Appetite 5 1984 147 158
    • (1984) Appetite , vol.5 , pp. 147-158
    • Weingarten, H.P.1
  • 40
    • 0022343705 scopus 로고
    • Stimulus control of eating: Implications for a two-factor theory of hunger
    • H.P. Weingarten Stimulus control of eating: Implications for a two-factor theory of hunger Appetite 6 1985 387 401
    • (1985) Appetite , vol.6 , pp. 387-401
    • Weingarten, H.P.1
  • 41
    • 24744453295 scopus 로고    scopus 로고
    • Amygdalar and prefrontal pathways to the lateral hypothalamus are activated by a learned cue that stimulates eating
    • G.D. Petrovich, P.C. Holland, and M. Gallagher Amygdalar and prefrontal pathways to the lateral hypothalamus are activated by a learned cue that stimulates eating J Neurosci 25 2005 8295 8302
    • (2005) J Neurosci , vol.25 , pp. 8295-8302
    • Petrovich, G.D.1    Holland, P.C.2    Gallagher, M.3
  • 43
    • 0036812537 scopus 로고    scopus 로고
    • Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating
    • G.D. Petrovich, B. Setlow, P.C. Holland, and M. Gallagher Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating J Neurosci 22 2002 8748 8753
    • (2002) J Neurosci , vol.22 , pp. 8748-8753
    • Petrovich, G.D.1    Setlow, B.2    Holland, P.C.3    Gallagher, M.4
  • 44
    • 0024354678 scopus 로고
    • Mechanisms of conditioned meal initiation
    • H.P. Weingarten, and G.M. Martin Mechanisms of conditioned meal initiation Physiol Behav 45 1989 735 740
    • (1989) Physiol Behav , vol.45 , pp. 735-740
    • Weingarten, H.P.1    Martin, G.M.2
  • 45
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • A.M. Wren, C.J. Small, H.L. Ward, K.G. Murphy, C.L. Dakin, and S. Taheri The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion Endocrinology 141 2000 4325 4328
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5    Taheri, S.6
  • 46
    • 33748362868 scopus 로고    scopus 로고
    • Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: Implications for its involvement in brain reward
    • E. Jerlhag, E. Egecioglu, S.L. Dickson, M. Andersson, L. Svensson, and J.A. Engel Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: Implications for its involvement in brain reward Addict Biol 11 2006 45 54
    • (2006) Addict Biol , vol.11 , pp. 45-54
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Andersson, M.4    Svensson, L.5    Engel, J.A.6
  • 47
    • 77956450412 scopus 로고    scopus 로고
    • Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis
    • L. Yao, P. Fan, M. Arolfo, Z. Jiang, M.F. Olive, and J. Zablocki Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis Nat Med 16 2010 1024 1028
    • (2010) Nat Med , vol.16 , pp. 1024-1028
    • Yao, L.1    Fan, P.2    Arolfo, M.3    Jiang, Z.4    Olive, M.F.5    Zablocki, J.6
  • 48
    • 0035320507 scopus 로고    scopus 로고
    • Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration
    • E.F. Schmidt, M.A. Sutton, C.A. Schad, D.A. Karanian, E.S. Brodkin, and D.W. Self Extinction training regulates tyrosine hydroxylase during withdrawal from cocaine self-administration J Neurosci 21 2001 RC137
    • (2001) J Neurosci , vol.21 , pp. 137
    • Schmidt, E.F.1    Sutton, M.A.2    Schad, C.A.3    Karanian, D.A.4    Brodkin, E.S.5    Self, D.W.6
  • 49
    • 33744786237 scopus 로고    scopus 로고
    • Lateral ventricular ghrelin and fourth ventricular ghrelin induce similar increases in food intake and patterns of hypothalamic gene expression
    • K.P. Kinzig, K.A. Scott, J. Hyun, S. Bi, and T.H. Moran Lateral ventricular ghrelin and fourth ventricular ghrelin induce similar increases in food intake and patterns of hypothalamic gene expression Am J Physiol Regul Integr Comp Physiol 290 2006 R1565 R1569
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Kinzig, K.P.1    Scott, K.A.2    Hyun, J.3    Bi, S.4    Moran, T.H.5
  • 50
    • 21344451852 scopus 로고    scopus 로고
    • Distinct forebrain and caudal brainstem contributions to the neuropeptide y mediation of ghrelin hyperphagia
    • L.F. Faulconbridge, H.J. Grill, and J.M. Kaplan Distinct forebrain and caudal brainstem contributions to the neuropeptide Y mediation of ghrelin hyperphagia Diabetes 54 2005 1985 1993
    • (2005) Diabetes , vol.54 , pp. 1985-1993
    • Faulconbridge, L.F.1    Grill, H.J.2    Kaplan, J.M.3
  • 52
    • 73549123839 scopus 로고    scopus 로고
    • Are the dorsal and ventral hippocampus functionally distinct structures?
    • M.S. Fanselow, and H.W. Dong Are the dorsal and ventral hippocampus functionally distinct structures? Neuron 65 2010 7 19
    • (2010) Neuron , vol.65 , pp. 7-19
    • Fanselow, M.S.1    Dong, H.W.2
  • 53
    • 79952623083 scopus 로고    scopus 로고
    • Gastric distention induced functional magnetic resonance signal changes in the rodent brain
    • D.K. Min, U.I. Tuor, and P.K. Chelikani Gastric distention induced functional magnetic resonance signal changes in the rodent brain Neuroscience 179 2011 151 158
    • (2011) Neuroscience , vol.179 , pp. 151-158
    • Min, D.K.1    Tuor, U.I.2    Chelikani, P.K.3
  • 54
    • 80054862764 scopus 로고    scopus 로고
    • Changes in differential functional magnetic resonance signals in the rodent brain elicited by mixed-nutrient or protein-enriched meals
    • D.K. Min, U.I. Tuor, H.S. Koopmans, and P.K. Chelikani Changes in differential functional magnetic resonance signals in the rodent brain elicited by mixed-nutrient or protein-enriched meals Gastroenterology 141 2011 1832 1841
    • (2011) Gastroenterology , vol.141 , pp. 1832-1841
    • Min, D.K.1    Tuor, U.I.2    Koopmans, H.S.3    Chelikani, P.K.4
  • 55
    • 79959776254 scopus 로고    scopus 로고
    • Energy density, portion size, and eating occasions: Contributions to increased energy intake in the United States, 1977-2006
    • K.J. Duffey, and B.M. Popkin Energy density, portion size, and eating occasions: Contributions to increased energy intake in the United States, 1977-2006 PLoS Med 8 2011 e1001050
    • (2011) PLoS Med , vol.8 , pp. 1001050
    • Duffey, K.J.1    Popkin, B.M.2
  • 56
    • 0002827587 scopus 로고    scopus 로고
    • Food advertising in the United States
    • E. Frazao, United States Department of Agriculture Washington, DC
    • A.E. Gallo Food advertising in the United States E. Frazao, America's Eating Habits: Changes and Consequences 1999 United States Department of Agriculture Washington, DC 173 180
    • (1999) America's Eating Habits: Changes and Consequences , pp. 173-180
    • Gallo, A.E.1
  • 57
    • 80555131167 scopus 로고    scopus 로고
    • Motivation to obtain preferred foods is enhanced by ghrelin in the ventral tegmental area
    • S.J. King, A.M. Isaacs, E. O'Farrell, and A. Abizaid Motivation to obtain preferred foods is enhanced by ghrelin in the ventral tegmental area Horm Behav 60 2011 572 580
    • (2011) Horm Behav , vol.60 , pp. 572-580
    • King, S.J.1    Isaacs, A.M.2    O'Farrell, E.3    Abizaid, A.4
  • 58
    • 33749504710 scopus 로고    scopus 로고
    • Effects of dorsal and ventral hippocampal NMDA stimulation on nucleus accumbens core and shell dopamine release
    • D. Peleg-Raibstein, and J. Feldon Effects of dorsal and ventral hippocampal NMDA stimulation on nucleus accumbens core and shell dopamine release Neuropharmacology 51 2006 947 957
    • (2006) Neuropharmacology , vol.51 , pp. 947-957
    • Peleg-Raibstein, D.1    Feldon, J.2
  • 60
    • 33947157380 scopus 로고    scopus 로고
    • Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin
    • K.W. Davis, P.J. Wellman, and P.S. Clifford Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin Regul Pept 140 2007 148 152
    • (2007) Regul Pept , vol.140 , pp. 148-152
    • Davis, K.W.1    Wellman, P.J.2    Clifford, P.S.3
  • 61
    • 44649167592 scopus 로고    scopus 로고
    • Hippocampal regulation of contextual cue-induced reinstatement of cocaine-seeking behavior
    • A.L. Atkins, Y. Mashhoon, and K.M. Kantak Hippocampal regulation of contextual cue-induced reinstatement of cocaine-seeking behavior Pharmacol Biochem Behav 90 2008 481 491
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 481-491
    • Atkins, A.L.1    Mashhoon, Y.2    Kantak, K.M.3
  • 62
    • 78349311582 scopus 로고    scopus 로고
    • Sub-region specific contribution of the ventral hippocampus to drug context-induced reinstatement of cocaine-seeking behavior in rats
    • H.C. Lasseter, X. Xie, D.R. Ramirez, and R.A. Fuchs Sub-region specific contribution of the ventral hippocampus to drug context-induced reinstatement of cocaine-seeking behavior in rats Neuroscience 171 2010 830 839
    • (2010) Neuroscience , vol.171 , pp. 830-839
    • Lasseter, H.C.1    Xie, X.2    Ramirez, D.R.3    Fuchs, R.A.4
  • 63
    • 30044447631 scopus 로고    scopus 로고
    • Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
    • G.J. Morton, R.W. Gelling, K.D. Niswender, C.D. Morrison, C.J. Rhodes, and M.W. Schwartz Leptin regulates insulin sensitivity via phosphatidylinositol- 3-OH kinase signaling in mediobasal hypothalamic neurons Cell Metab 2 2005 411 420
    • (2005) Cell Metab , vol.2 , pp. 411-420
    • Morton, G.J.1    Gelling, R.W.2    Niswender, K.D.3    Morrison, C.D.4    Rhodes, C.J.5    Schwartz, M.W.6
  • 65
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • M. Kojima, H. Hosoda, Y. Date, M. Nakazato, H. Matsuo, and K. Kangawa Ghrelin is a growth-hormone-releasing acylated peptide from stomach Nature 402 1999 656 660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 67
    • 21644453934 scopus 로고    scopus 로고
    • Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase
    • B. Kola, E. Hubina, S.A. Tucci, T.C. Kirkham, E.A. Garcia, and S.E. Mitchell Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase J Biol Chem 280 2005 25196 25201
    • (2005) J Biol Chem , vol.280 , pp. 25196-25201
    • Kola, B.1    Hubina, E.2    Tucci, S.A.3    Kirkham, T.C.4    Garcia, E.A.5    Mitchell, S.E.6
  • 69
    • 79952444784 scopus 로고    scopus 로고
    • Ghrelin-induced activation of cAMP signal transduction and its negative regulation by endocannabinoids in the hippocampus
    • J.N. Cuellar, and M. Isokawa Ghrelin-induced activation of cAMP signal transduction and its negative regulation by endocannabinoids in the hippocampus Neuropharmacology 60 2011 842 851
    • (2011) Neuropharmacology , vol.60 , pp. 842-851
    • Cuellar, J.N.1    Isokawa, M.2
  • 70
    • 77957274035 scopus 로고    scopus 로고
    • Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons
    • D.I. Briggs, P.J. Enriori, M.B. Lemus, M.A. Cowley, and Z.B. Andrews Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons Endocrinology 151 2010 4745 4755
    • (2010) Endocrinology , vol.151 , pp. 4745-4755
    • Briggs, D.I.1    Enriori, P.J.2    Lemus, M.B.3    Cowley, M.A.4    Andrews, Z.B.5
  • 71
    • 84858442076 scopus 로고    scopus 로고
    • Diet-induced obesity blunts the behavioural effects of ghrelin: Studies in a mouse-progressive ratio task
    • B.C. Finger, T.G. Dinan, and J.F. Cryan Diet-induced obesity blunts the behavioural effects of ghrelin: Studies in a mouse-progressive ratio task Psychopharmacology (Berl) 220 2012 173 181
    • (2012) Psychopharmacology (Berl) , vol.220 , pp. 173-181
    • Finger, B.C.1    Dinan, T.G.2    Cryan, J.F.3
  • 73
    • 9244219587 scopus 로고    scopus 로고
    • Region-specific leptin resistance within the hypothalamus of diet-induced obese mice
    • H. Munzberg, J.S. Flier, and C. Bjorbaek Region-specific leptin resistance within the hypothalamus of diet-induced obese mice Endocrinology 145 2004 4880 4889
    • (2004) Endocrinology , vol.145 , pp. 4880-4889
    • Munzberg, H.1    Flier, J.S.2    Bjorbaek, C.3
  • 74
    • 33847231925 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake
    • V.P. Carlini, R.C. Gaydou, H.B. Schioth, and S.R. de Barioglio Selective serotonin reuptake inhibitor (fluoxetine) decreases the effects of ghrelin on memory retention and food intake Regul Pept 140 2007 65 73
    • (2007) Regul Pept , vol.140 , pp. 65-73
    • Carlini, V.P.1    Gaydou, R.C.2    Schioth, H.B.3    De Barioglio, S.R.4
  • 75
    • 77952104811 scopus 로고    scopus 로고
    • Ghrelin and memory: Differential effects on acquisition and retrieval
    • V.P. Carlini, M. Ghersi, H.B. Schioth, and S.R. de Barioglio Ghrelin and memory: Differential effects on acquisition and retrieval Peptides 31 2010 1190 1193
    • (2010) Peptides , vol.31 , pp. 1190-1193
    • Carlini, V.P.1    Ghersi, M.2    Schioth, H.B.3    De Barioglio, S.R.4
  • 76
    • 44149094016 scopus 로고    scopus 로고
    • Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration
    • V.P. Carlini, A.C. Martini, H.B. Schioth, R.D. Ruiz, M. Fiol de Cuneo, and S.R. de Barioglio Decreased memory for novel object recognition in chronically food-restricted mice is reversed by acute ghrelin administration Neuroscience 153 2008 929 934
    • (2008) Neuroscience , vol.153 , pp. 929-934
    • Carlini, V.P.1    Martini, A.C.2    Schioth, H.B.3    Ruiz, R.D.4    Fiol De Cuneo, M.5    De Barioglio, S.R.6
  • 77
    • 0347064001 scopus 로고    scopus 로고
    • Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin
    • V.P. Carlini, M.M. Varas, A.B. Cragnolini, H.B. Schioth, T.N. Scimonelli, and S.R. de Barioglio Differential role of the hippocampus, amygdala, and dorsal raphe nucleus in regulating feeding, memory, and anxiety-like behavioral responses to ghrelin Biochem Biophys Res Commun 313 2004 635 641
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 635-641
    • Carlini, V.P.1    Varas, M.M.2    Cragnolini, A.B.3    Schioth, H.B.4    Scimonelli, T.N.5    De Barioglio, S.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.