Using case-parent trios to look for rare de novo genetic variants in adult-onset neurodegenerative diseases

Journal of Neuroscience Methods

Volumn 197, Issue 2, 2011, Pages 297-301

  Pamphlett, Roger ^a   Morahan, Julia M ^a   Yu, Bing ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Amyotrophic lateral sclerosis; Copy number; De novo mutation; Genome wide microarray; Motor neuron disease; Neurodegeneration; Trio study

Indexed keywords

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL ARTICLE; COPY NUMBER VARIATION; DNA DETERMINATION; FEMALE; GENETIC VARIABILITY; HUMAN; MALE; MICROARRAY ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGE OF ONSET; AGED; AMYOTROPHIC LATERAL SCLEROSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; MALE; MIDDLE AGED;

EID: 79954994064     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.02.028     Document Type: Article

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