메뉴 건너뛰기




Volumn 10, Issue 5, 2014, Pages 302-310

Glucagon-like peptide 1 and the cardiovascular system

Author keywords

Cardiovascular; Glucagon like peptide 1; Incretin

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; INCRETIN; LIRAGLUTIDE; METFORMIN; SAXAGLIPTIN; SITAGLIPTIN; VILDAGLIPTIN; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; TRIACYLGLYCEROL;

EID: 84925882595     PISSN: 15733998     EISSN: 18756417     Source Type: Journal    
DOI: 10.2174/1573399810666141030125830     Document Type: Article
Times cited : (25)

References (135)
  • 2
    • 0029043139 scopus 로고
    • Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulinreleasing polypeptide
    • Fehmann HC, Göke R, Göke B. Cell and molecular biology of the incretin hormones glucagon-like peptide-I and glucose-dependent insulinreleasing polypeptide. Endocr Rev 1995; 16(3): 390-410.
    • (1995) Endocr Rev , vol.16 , Issue.3 , pp. 390-410
    • Fehmann, H.C.1    Göke, R.2    Göke, B.3
  • 3
    • 33745771673 scopus 로고    scopus 로고
    • Biologic actions and therapeutic potential of the glucagon- like peptides. Nature Clinical Practice
    • Drucker DJ. Biologic actions and therapeutic potential of the glucagon- like peptides. Nature Clinical Practice. Endocrinology and Metabolism 2005; 1: 22-31.
    • (2005) Endocrinology and Metabolism , vol.1 , pp. 22-31
    • Drucker, D.J.1
  • 5
    • 0028803336 scopus 로고
    • Both subcutaneously and intravenously administered glucagonlike peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects
    • Deacon CF, Nauck MA, Toft-Nielsen M, Pridal L, Willms B, Holst JJ. Both subcutaneously and intravenously administered glucagonlike peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects. Diabetes 1995; 44(9): 1126-31.
    • (1995) Diabetes , vol.44 , Issue.9 , pp. 1126-1131
    • Deacon, C.F.1    Nauck, M.A.2    Toft-Nielsen, M.3    Pridal, L.4    Willms, B.5    Holst, J.J.6
  • 6
    • 0037928769 scopus 로고    scopus 로고
    • The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: In vivo metabolism of pituitary adenylate cyclase activating polypeptide-(1- 38)
    • Zhu L, Tamvakopoulos C, Xie D, et al.The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: in vivo metabolism of pituitary adenylate cyclase activating polypeptide-(1- 38) J Biol Chem 2003; 278: 22418-23.
    • (2003) J Biol Chem , vol.278 , pp. 22418-22423
    • Zhu, L.1    Tamvakopoulos, C.2    Xie, D.3
  • 7
    • 33749368018 scopus 로고    scopus 로고
    • Oxyntomodulin: A novel potential treatment for obesity
    • Druce MR, Bloom SR. Oxyntomodulin: a novel potential treatment for obesity. Treatments in Endocrinology 2006; 5: 265-72.
    • (2006) Treatments in Endocrinology , vol.5 , pp. 265-272
    • Druce, M.R.1    Bloom, S.R.2
  • 8
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon- like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
    • Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon- like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993; 36(8): 741-4.
    • (1993) Diabetologia , vol.36 , Issue.8 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Orskov, C.3    Holst, J.J.4    Willms, B.5    Creutzfeldt, W.6
  • 9
    • 84865374900 scopus 로고    scopus 로고
    • The once-daily human glucagon-like peptide-1 analog, liraglutide, improves b-cell function in Japanese patients with type 2 diabetes
    • Seino Y, Rasmussen MF, Clauson P, Kaku K. The once-daily human glucagon-like peptide-1 analog, liraglutide, improves b-cell function in Japanese patients with type 2 diabetes. J Diabetes Inv 2012; 3(4): 388-95.
    • (2012) J Diabetes Inv , vol.3 , Issue.4 , pp. 388-395
    • Seino, Y.1    Rasmussen, M.F.2    Clauson, P.3    Kaku, K.4
  • 13
    • 84862945912 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 enhances glucokinase activity in pancreatic b-cells through the association of Epac2 with Rim2 and Rab3A. Glucagon-like peptide-1 enhances glucokinase activity in pancreatic b-cells through the association of Epac2 with Rim2 and Rab3A
    • Park JH, Kim SJ, Park SH, Son DG, Bae JH, Kim HK, Han J, Song DK. Glucagon-like peptide-1 enhances glucokinase activity in pancreatic b-cells through the association of Epac2 with Rim2 and Rab3A. Glucagon-like peptide-1 enhances glucokinase activity in pancreatic b-cells through the association of Epac2 with Rim2 and Rab3A. Endocrinology 2012; 153(2): 574-82.
    • (2012) Endocrinology , vol.153 , Issue.2 , pp. 574-582
    • Park, J.H.1    Kim, S.J.2    Park, S.H.3    Son, D.G.4    Bae, J.H.5    Kim, H.K.6    Han, J.7    Song, D.K.8
  • 14
    • 79955778281 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 stimulates post-translational activation of glucokinase in pancreatic beta cells
    • Ding SY, Nkobena A, Kraft CA, Markwardt ML, Rizzo MA. Glucagon-like peptide 1 stimulates post-translational activation of glucokinase in pancreatic beta cells. J Biol Chem 2011; 286(19): 16768-74.
    • (2011) J Biol Chem , vol.286 , Issue.19 , pp. 16768-16774
    • Ding, S.Y.1    Nkobena, A.2    Kraft, C.A.3    Markwardt, M.L.4    Rizzo, M.A.5
  • 15
    • 0041375468 scopus 로고    scopus 로고
    • Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells
    • Arnette D, Gibson TB, Lawrence MC, et al.Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells. J Biol Chem 2003; 278: 32517-25.
    • (2003) J Biol Chem , vol.278 , pp. 32517-32525
    • Arnette, D.1    Gibson, T.B.2    Lawrence, M.C.3
  • 16
    • 84863277601 scopus 로고    scopus 로고
    • Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1
    • Selway J, Rigatti R, Storey N, Lu J, Willars GB, Herbert TP. Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1. PLoS One 2012; 7(3): e3300.
    • (2012) Plos One , vol.7 , Issue.3 , pp. 3300
    • Selway, J.1    Rigatti, R.2    Storey, N.3    Lu, J.4    Willars, G.B.5    Herbert, T.P.6
  • 18
    • 84884378157 scopus 로고    scopus 로고
    • Differential protective effects of exenatide, an agonist of GLP-1 receptor and Piragliatin, a glucokinase activator in beta cell response to streptozotocin-induced and endoplasmic reticulum stresses
    • Kim MK, Cho JH, Lee JJ, Cheong YH, Son MH, Lee KJ. Differential protective effects of exenatide, an agonist of GLP-1 receptor and Piragliatin, a glucokinase activator in beta cell response to streptozotocin-induced and endoplasmic reticulum stresses. PLoS One 2013; 8(9): e73340.
    • (2013) Plos One , vol.8 , Issue.9
    • Kim, M.K.1    Cho, J.H.2    Lee, J.J.3    Cheong, Y.H.4    Son, M.H.5    Lee, K.J.6
  • 19
    • 84862182799 scopus 로고    scopus 로고
    • Exendin-4 reduces glycemia by increasing liver glucokinase activity: An insulin independent effect
    • Dhanesha N, Joharapurkar A, Shah G, Dhote V, Kshirsagar S, Bahekar R, Jain M. Exendin-4 reduces glycemia by increasing liver glucokinase activity: an insulin independent effect. Pharmacol Rep 2012; 64(1): 140-9.
    • (2012) Pharmacol Rep , vol.64 , Issue.1 , pp. 140-149
    • Dhanesha, N.1    Joharapurkar, A.2    Shah, G.3    Dhote, V.4    Kshirsagar, S.5    Bahekar, R.6    Jain, M.7
  • 20
    • 77956230708 scopus 로고    scopus 로고
    • Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus
    • Schwartz EA, Koska J, Mullin MP, Syoufi I, Schwenke DC, Reaven PD. Exenatide suppresses postprandial elevations in lipids and lipoproteins in individuals with impaired glucose tolerance and recent onset type 2 diabetes mellitus. Atherosclerosis 2010; 212(1): 217-22.
    • (2010) Atherosclerosis , vol.212 , Issue.1 , pp. 217-222
    • Schwartz, E.A.1    Koska, J.2    Mullin, M.P.3    Syoufi, I.4    Schwenke, D.C.5    Reaven, P.D.6
  • 22
  • 25
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller JP, Drewe J, Göke B, Schmidt H, Rohrer B, Lareida J, Beglinger C. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999; 276(5 Pt 2): R1541-4.
    • (1999) Am J Physiol , vol.276
    • Gutzwiller, J.P.1    Drewe, J.2    Göke, B.3    Schmidt, H.4    Rohrer, B.5    Lareida, J.6    Beglinger, C.7
  • 27
    • 0032005005 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
    • Flint A, Raben A, Astrup A, Holst JJ. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998; 101(3): 515-20.
    • (1998) J Clin Invest , vol.101 , Issue.3 , pp. 515-520
    • Flint, A.1    Raben, A.2    Astrup, A.3    Holst, J.J.4
  • 28
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002; 143(11): 4397-408.
    • (2002) Endocrinology , vol.143 , Issue.11 , pp. 4397-4408
    • Farilla, L.1    Hui, H.2    Bertolotto, C.3    Kang, E.4    Bulotta, A.5    Di Mario, U.6    Perfetti, R.7
  • 29
    • 23944479411 scopus 로고    scopus 로고
    • Glucagon-like peptide- 1 protects beta cells from cytokine-induced apoptosis and necrosis: Role of protein kinase B
    • Li L, El-Kholy W, Rhodes CJ, Brubaker PL. Glucagon-like peptide- 1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B. Diabetologia 2005; 48(7): 1339-49.
    • (2005) Diabetologia , vol.48 , Issue.7 , pp. 1339-1349
    • Li, L.1    El-Kholy, W.2    Rhodes, C.J.3    Brubaker, P.L.4
  • 30
    • 1842855402 scopus 로고    scopus 로고
    • Glucagonlike peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells
    • Wang Q, Li L, Xu E, Wong V, Rhodes C, Brubaker PL. Glucagonlike peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells. Diabetologia 2004; 47(3): 478-87.
    • (2004) Diabetologia , vol.47 , Issue.3 , pp. 478-487
    • Wang, Q.1    Li, L.2    Xu, E.3    Wong, V.4    Rhodes, C.5    Brubaker, P.L.6
  • 31
    • 84865224952 scopus 로고    scopus 로고
    • Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreaticb-cell line
    • Wei Q, Sun YQ, Zhang J. Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic b-cell line. Peptides 2012; 37(1): 18-24.
    • (2012) Peptides , vol.37 , Issue.1 , pp. 18-24
    • Wei, Q.1    Sun, Y.Q.2    Zhang, J.3
  • 33
    • 77955019118 scopus 로고    scopus 로고
    • Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: Potential involvement of AKT and mitochondria biogenesis
    • Fan R, Li X, Gu X, Chan JC, Xu G. Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis. Diabetes Obes Metab 2010; 12(9): 815-24.
    • (2010) Diabetes Obes Metab , vol.12 , Issue.9 , pp. 815-824
    • Fan, R.1    Li, X.2    Gu, X.3    Chan, J.C.4    Xu, G.5
  • 35
    • 79955821979 scopus 로고    scopus 로고
    • Effect of sitagliptin plus metformin onb-cell function, islet integrity and islet gene expression in Zucker diabetic fatty rats
    • Han SJ, Choi SE, Kang Y, Jung JG, Yi SA, Kim HJ, Lee KW, Kim DJ. Effect of sitagliptin plus metformin on b-cell function, islet integrity and islet gene expression in Zucker diabetic fatty rats. Diabetes Res Clin Pract 2011; 92(2): 213-22.
    • (2011) Diabetes Res Clin Pract , vol.92 , Issue.2 , pp. 213-222
    • Han, S.J.1    Choi, S.E.2    Kang, Y.3    Jung, J.G.4    Yi, S.A.5    Kim, H.J.6    Lee, K.W.7    Kim, D.J.8
  • 37
    • 84878365678 scopus 로고    scopus 로고
    • The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: Implications in type 2 diabetes and islet transplantation
    • Park YJ, Ao Z, Kieffer TJ, Chen H, Safikhan N, Thompson DM, Meloche M, Warnock GL, Marzban L. The glucagon-like peptide-1 receptor agonist exenatide restores impaired pro-islet amyloid polypeptide processing in cultured human islets: implications in type 2 diabetes and islet transplantation. Diabetologia 2013; 56(3): 508-19.
    • (2013) Diabetologia , vol.56 , Issue.3 , pp. 508-519
    • Park, Y.J.1    Ao, Z.2    Kieffer, T.J.3    Chen, H.4    Safikhan, N.5    Thompson, D.M.6    Meloche, M.7    Warnock, G.L.8    Marzban, L.9
  • 38
    • 53749089728 scopus 로고    scopus 로고
    • Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice
    • Suarez-Pinzon WL, Lakey JR, Rabinovitch A. Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice. Cell Transplant 2008; 17(6): 631-40.
    • (2008) Cell Transplant , vol.17 , Issue.6 , pp. 631-640
    • Suarez-Pinzon, W.L.1    Lakey, J.R.2    Rabinovitch, A.3
  • 39
    • 84862576179 scopus 로고    scopus 로고
    • The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3- kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways
    • Favaro E, Granata R, Miceli I, Baragli A, Settanni F, Cavallo Perin P, Ghigo E, Camussi G, Zanone MM. The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3- kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways. Diabetologia 2012; 55(4): 1058-70.
    • (2012) Diabetologia , vol.55 , Issue.4 , pp. 1058-1070
    • Favaro, E.1    Granata, R.2    Miceli, I.3    Baragli, A.4    Settanni, F.5    Cavallo Perin, P.6    Ghigo, E.7    Camussi, G.8    Zanone, M.M.9
  • 40
    • 48949088649 scopus 로고    scopus 로고
    • Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal- regulated kinase 1/2 pathway inhibition: Protective role of glucagon- like peptide -1
    • Blandino-Rosano M, Perez-Arana G, Mellado-Gil JM, Segundo C, Aguilar-Diosdado M. Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal- regulated kinase 1/2 pathway inhibition: protective role of glucagon- like peptide -1. J Mol Endocrinol 2008; 41(1): 35-44.
    • (2008) J Mol Endocrinol , vol.41 , Issue.1 , pp. 35-44
    • Blandino-Rosano, M.1    Perez-Arana, G.2    Mellado-Gil, J.M.3    Segundo, C.4    Aguilar-Diosdado, M.5
  • 41
    • 0030013475 scopus 로고    scopus 로고
    • Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor
    • Bullock, BP. Heller RS. Habener, JF. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology 1996; 137: 2968-78.
    • (1996) Endocrinology , vol.137 , pp. 2968-2978
    • Bullock, B.P.1    Heller, R.S.2    Habener, J.F.3
  • 42
    • 84897902330 scopus 로고    scopus 로고
    • Exogenous glucagon-like peptide 1 reduces contractions in human colon circular muscle
    • Amato A, Baldassano S, Liotta R, Serio R, Mulè F. Exogenous glucagon-like peptide 1 reduces contractions in human colon circular muscle. J Endocrinol 2014; 221(1): 29-37.
    • (2014) J Endocrinol , vol.221 , Issue.1 , pp. 29-37
    • Amato, A.1    Baldassano, S.2    Liotta, R.3    Serio, R.4    Mulè, F.5
  • 44
    • 77951436599 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
    • Gupta NA, Mells J, Dunham RM, Grakoui A, Handy J, Saxena NK, et al.Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology 2010; 51: 1584-92.
    • (2010) Hepatology , vol.51 , pp. 1584-1592
    • Gupta, N.A.1    Mells, J.2    Dunham, R.M.3    Grakoui, A.4    Handy, J.5    Saxena, N.K.6
  • 45
    • 8544258807 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease
    • Nyström T, Gutniak MK, Zhang Q, Zhang F, Holst JJ, Ahrén B, Sjöholm A. Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol Endocrinol Metab. 2004; 287(6): E1209-15.
    • (2004) Am J Physiol Endocrinol Metab , vol.287 , Issue.6
    • Nyström, T.1    Gutniak, M.K.2    Zhang, Q.3    Zhang, F.4    Holst, J.J.5    Ahrén, B.6    Sjöholm, A.7
  • 46
    • 43249089631 scopus 로고    scopus 로고
    • Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
    • Ban K, Noyan-Ashraf MH, Hoefer J, Bolz SS, Drucker DJ, Husain M. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008; 117(18): 2340-50.
    • (2008) Circulation , vol.117 , Issue.18 , pp. 2340-2350
    • Ban, K.1    Noyan-Ashraf, M.H.2    Hoefer, J.3    Bolz, S.S.4    Drucker, D.J.5    Husain, M.6
  • 48
    • 84866546292 scopus 로고    scopus 로고
    • Exendin-4 directly improves endothelial dysfunction in isolated aortas from obese rats through the cAMP or AMPK-eNOS pathways
    • Han L, Yu Y, Sun X, Wang B. Exendin-4 directly improves endothelial dysfunction in isolated aortas from obese rats through the cAMP or AMPK-eNOS pathways. Diabetes Res Clin Pract 2012; 97(3): 453-60.
    • (2012) Diabetes Res Clin Pract , vol.97 , Issue.3 , pp. 453-460
    • Han, L.1    Yu, Y.2    Sun, X.3    Wang, B.4
  • 49
    • 79959237560 scopus 로고    scopus 로고
    • A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model
    • Gaspari T, Liu H, Welungoda I, Hu Y, Widdop RE, Knudsen LB, Simpson RW, Dear AE. A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model. Diab Vasc Dis Res 2011; 8(2): 117-24.
    • (2011) Diab Vasc Dis Res , vol.8 , Issue.2 , pp. 117-124
    • Gaspari, T.1    Liu, H.2    Welungoda, I.3    Hu, Y.4    Widdop, R.E.5    Knudsen, L.B.6    Simpson, R.W.7    Dear, A.E.8
  • 51
    • 84855428526 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells
    • Ding L, Zhang J. Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells. Acta Pharmacol Sin 2012; 33(1): 75-81.
    • (2012) Acta Pharmacol Sin , vol.33 , Issue.1 , pp. 75-81
    • Ding, L.1    Zhang, J.2
  • 52
    • 77958052010 scopus 로고    scopus 로고
    • A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts antiinflammatory action in endothelial cells
    • Hattori Y, Jojima T, Tomizawa A, Satoh H, Hattori S, Kasai K, Hayashi T. A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts antiinflammatory action in endothelial cells. Diabetologia 2010; 53(10): 2256-63.
    • (2010) Diabetologia , vol.53 , Issue.10 , pp. 2256-2263
    • Hattori, Y.1    Jojima, T.2    Tomizawa, A.3    Satoh, H.4    Hattori, S.5    Kasai, K.6    Hayashi, T.7
  • 54
    • 77954948794 scopus 로고    scopus 로고
    • Improvement of postprandial endothelial function after a single dose of exenatide in individuals with impaired glucose tolerance and recent-onset type 2 diabetes
    • Koska J, Schwartz EA, Mullin MP, Schwenke DC, Reaven PD. Improvement of postprandial endothelial function after a single dose of exenatide in individuals with impaired glucose tolerance and recent-onset type 2 diabetes. Diabetes Care 2010; 33(5): 1028-30.
    • (2010) Diabetes Care , vol.33 , Issue.5 , pp. 1028-1030
    • Koska, J.1    Schwartz, E.A.2    Mullin, M.P.3    Schwenke, D.C.4    Reaven, P.D.5
  • 55
    • 84871825708 scopus 로고    scopus 로고
    • Exenatide improves endothelial function assessed by flow mediated dilation technique in subjects with type 2 diabetes: Results from an observational research
    • Irace C, De Luca S, Shehaj E, Carallo C, Loprete A, Scavelli F, Gnasso A. Exenatide improves endothelial function assessed by flow mediated dilation technique in subjects with type 2 diabetes: results from an observational research. Diab Vasc Dis Res 2013; 10(1): 72-7.
    • (2013) Diab Vasc Dis Res , vol.10 , Issue.1 , pp. 72-77
    • Irace, C.1    De Luca, S.2    Shehaj, E.3    Carallo, C.4    Loprete, A.5    Scavelli, F.6    Gnasso, A.7
  • 57
    • 83455230038 scopus 로고    scopus 로고
    • Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
    • van Poppel PC, Netea MG, Smits P, Tack CJ. Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care 2011; 34(9): 2072-7.
    • (2011) Diabetes Care , vol.34 , Issue.9 , pp. 2072-2077
    • Van Poppel, P.C.1    Netea, M.G.2    Smits, P.3    Tack, C.J.4
  • 58
    • 84918835984 scopus 로고    scopus 로고
    • Exendin-4 Inhibits HMGB1-Induced Inflammatory Responses in HUVECs and in Murine Polymicrobial Sepsis
    • Lee W, Ku SK, Park EJ, Na DH, Kim KM, Bae JS. Exendin-4 Inhibits HMGB1-Induced Inflammatory Responses in HUVECs and in Murine Polymicrobial Sepsis. Inflammation 2014; 37(5): 1876-88.
    • (2014) Inflammation , vol.37 , Issue.5 , pp. 1876-1888
    • Lee, W.1    Ku, S.K.2    Park, E.J.3    Na, D.H.4    Kim, K.M.5    Bae, J.S.6
  • 59
    • 84901341959 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism
    • Krasner NM, Ido Y, Ruderman NB, Cacicedo JM. Glucagon-like peptide-1 (GLP-1) analog liraglutide inhibits endothelial cell inflammation through a calcium and AMPK dependent mechanism. PLoS One 2014; 9(5): e97554.
    • (2014) Plos One , vol.9 , Issue.5
    • Krasner, N.M.1    Ido, Y.2    Ruderman, N.B.3    Cacicedo, J.M.4
  • 60
    • 84865130603 scopus 로고    scopus 로고
    • Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function
    • Forst T, Michelson G, Ratter F, Weber MM, Anders S, Mitry M, Wilhelm B, Pfützner A. Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function. Diabet Med 2012; 29(9): 1115-8.
    • (2012) Diabet Med , vol.29 , Issue.9 , pp. 1115-1118
    • Forst, T.1    Michelson, G.2    Ratter, F.3    Weber, M.M.4    Ers, S.5    Mitry, M.6    Wilhelm, B.7    Pfützner, A.8
  • 61
    • 67650057935 scopus 로고    scopus 로고
    • A long-acting glucagon- like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules
    • Liu H, Dear AE, Knudsen LB, Simpson RW. A long-acting glucagon- like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules. J Endocrinol 2009; 201(1): 59-66.
    • (2009) J Endocrinol , vol.201 , Issue.1 , pp. 59-66
    • Liu, H.1    Dear, A.E.2    Knudsen, L.B.3    Simpson, R.W.4
  • 62
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    • Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R, Watada H. Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes 2010; 59(4): 1030-7.
    • (2010) Diabetes , vol.59 , Issue.4 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3    Ebato, C.4    Goto, H.5    Nomiyama, T.6    Fujitani, Y.7    Hirose, T.8    Kawamori, R.9    Watada, H.10
  • 63
    • 84866645242 scopus 로고    scopus 로고
    • Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: Role of dipeptidyl peptidase- IV inhibition
    • Rizzo MR, Barbieri M, Marfella R, Paolisso G. Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase- IV inhibition. Diabetes Care 2012; 35(10): 2076-82.
    • (2012) Diabetes Care , vol.35 , Issue.10 , pp. 2076-2082
    • Rizzo, M.R.1    Barbieri, M.2    Marfella, R.3    Paolisso, G.4
  • 64
    • 84899467577 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation
    • Dai Y, Mehta JL, Chen M. Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation. Cardiovasc Drugs Ther 2013; 27(5): 371-80.
    • (2013) Cardiovasc Drugs Ther , vol.27 , Issue.5 , pp. 371-380
    • Dai, Y.1    Mehta, J.L.2    Chen, M.3
  • 66
    • 77953959949 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activationof protein kinase A
    • Oeseburg H, de Boer RA, Buikema H, van der Harst P, van Gilst WH, Silljé HH. Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. Arterioscler Thromb Vasc Biol 2010; 30(7): 1407-14.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.7 , pp. 1407-1414
    • Oeseburg, H.1    De Boer, R.A.2    Buikema, H.3    Van Der Harst, P.4    Van Gilst, W.H.5    Silljé, H.H.6
  • 67
    • 84874931230 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism
    • Wang D, Luo P, Wang Y, Li W, Wang C, Sun D, Zhang R, Su T, Ma X, Zeng C, Wang H, Ren J, Cao F. Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism. Diabetes 2013; 62(5): 1697-708.
    • (2013) Diabetes , vol.62 , Issue.5 , pp. 1697-1708
    • Wang, D.1    Luo, P.2    Wang, Y.3    Li, W.4    Wang, C.5    Sun, D.6    Zhang, R.7    Su, T.8    Ma, X.9    Zeng, C.10    Wang, H.11    Ren, J.12    Cao, F.13
  • 68
    • 84875348947 scopus 로고    scopus 로고
    • Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways
    • Erdogdu O, Eriksson L, Xu H, Sjöholm A, Zhang Q, Nyström T. Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways. Mol Endocrinol 2013; 50(2): 229-41.
    • (2013) Mol Endocrinol , vol.50 , Issue.2 , pp. 229-241
    • Erdogdu, O.1    Eriksson, L.2    Xu, H.3    Sjöholm, A.4    Zhang, Q.5    Nyström, T.6
  • 69
    • 84877252041 scopus 로고    scopus 로고
    • Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a
    • Younce CW, Burmeister MA, Ayala JE. Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a. Am J Physiol Cell Physiol 2013; 304(6): C508-18.
    • (2013) Am J Physiol Cell Physiol , vol.304 , Issue.6
    • Younce, C.W.1    Burmeister, M.A.2    Ayala, J.E.3
  • 70
    • 84907227368 scopus 로고    scopus 로고
    • Liraglutide ameliorates renal injury in streptozotocin-induced diabetic rats by activating endothelial nitric oxide synthase activity via the downregulation of the nuclear factor-bB pathway
    • Zhou SJ, Bai L, Lv L, Chen R, Li CJ, Liu XY, Yu DM, Yu P. Liraglutide ameliorates renal injury in streptozotocin-induced diabetic rats by activating endothelial nitric oxide synthase activity via the downregulation of the nuclear factor-bB pathway. Mol Med Rep 2014; 10(5): 2587-94.
    • (2014) Mol Med Rep , vol.10 , Issue.5 , pp. 2587-2594
    • Zhou, S.J.1    Bai, L.2    Lv, L.3    Chen, R.4    Li, C.J.5    Liu, X.Y.6    Yu, D.M.7    Yu, P.8
  • 71
    • 33947099046 scopus 로고    scopus 로고
    • Acute effects of hyperglycaemia with and without exercise on endothelial function in healthy young men
    • Zhu W, Zhong C, Yu Y, Li K. Acute effects of hyperglycaemia with and without exercise on endothelial function in healthy young men. Eur J Appl Physiol 2007; 99(6), 585-91.
    • (2007) Eur J Appl Physiol , vol.99 , Issue.6 , pp. 585-591
    • Zhu, W.1    Zhong, C.2    Yu, Y.3    Li, K.4
  • 72
    • 0036021747 scopus 로고    scopus 로고
    • Endothelial dysfunction: Its relationship with acute hyperglycaemia and hyperlipidemia
    • Lee IK, Kim HS, Bae JH. Endothelial dysfunction: its relationship with acute hyperglycaemia and hyperlipidemia. Int J Clin Pract Suppl 2002; 129: 59-64.
    • (2002) Int J Clin Pract Suppl , vol.129 , pp. 59-64
    • Lee, I.K.1    Kim, H.S.2    Bae, J.H.3
  • 74
    • 0037015288 scopus 로고    scopus 로고
    • Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: Effects of shortand long-term simvastatin treatment
    • Ceriello, A. Taboga C, Tonutti L, Quagliaro L, Piconi L, Bais B, Da Ros R, Motz E. Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of shortand long-term simvastatin treatment. Circulation 2002; 106; 1211-18.
    • (2002) Circulation , vol.106 , pp. 1211-1218
    • Ceriello, A.1    Taboga, C.2    Tonutti, L.3    Quagliaro, L.4    Piconi, L.5    Bais, B.6    Da Ros, R.7    Motz, E.8
  • 75
    • 33645745733 scopus 로고    scopus 로고
    • Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes
    • Monnier L, Mas E, Ginet C, Michel F, Villon L, Cristol JP, Colette C. Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA 2006; 295(14): 1681-7.
    • (2006) JAMA , vol.295 , Issue.14 , pp. 1681-1687
    • Monnier, L.1    Mas, E.2    Ginet, C.3    Michel, F.4    Villon, L.5    Cristol, J.P.6    Colette, C.7
  • 76
    • 3543026291 scopus 로고    scopus 로고
    • Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: Implication for the oxidative stress associated with postprandial hyperglycemia
    • Yano M, Hasegawa G, Ishii M, et al.Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: implication for the oxidative stress associated with postprandial hyperglycemia. Redox Rep 2004; 9(2): 111-6.
    • (2004) Redox Rep , vol.9 , Issue.2 , pp. 111-116
    • Yano, M.1    Hasegawa, G.2    Ishii, M.3
  • 77
    • 85056063864 scopus 로고    scopus 로고
    • Association of postprandial hyperglycemia with in vitro LDL oxidation in nonsmoking patients with type 1 diabetes--a cross-sectional study
    • de Castro SH, Castro-Faria-Neto HC, Gomes MB. Association of postprandial hyperglycemia with in vitro LDL oxidation in nonsmoking patients with type 1 diabetes--a cross-sectional study. Rev Diabet Stud 2005; 2(3): 157-64.
    • (2005) Rev Diabet Stud , vol.2 , Issue.3 , pp. 157-164
    • De Castro, S.H.1    Castro-Faria-Neto, H.C.2    Gomes, M.B.3
  • 79
    • 0036267006 scopus 로고    scopus 로고
    • Hyperglycemia-induced apoptosis in the mouse myocardium
    • Cai L, Li W, Wang G, Jiang Y, Kang YJ. Hyperglycemia-induced apoptosis in the mouse myocardium. Diabetes 2002; 51: 1938-48.
    • (2002) Diabetes , vol.51 , pp. 1938-1948
    • Cai, L.1    Li, W.2    Wang, G.3    Jiang, Y.4    Kang, Y.J.5
  • 80
    • 33645053001 scopus 로고    scopus 로고
    • Prolonged deterioration of endothelial dysfunction in response to postprandial lipaemia is attenuated by vitamin C in Type 2 diabetes
    • Anderson RA, Evans LM, Ellis GR, et al.Prolonged deterioration of endothelial dysfunction in response to postprandial lipaemia is attenuated by vitamin C in Type 2 diabetes. Diabet Med 2006; 23(3): 258-64.
    • (2006) Diabet Med , vol.23 , Issue.3 , pp. 258-264
    • Anderson, R.A.1    Evans, L.M.2    Ellis, G.R.3
  • 81
    • 33644821275 scopus 로고    scopus 로고
    • Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: A randomized crossover study
    • Shimabukuro M, Higa N, Chinen I, Yamakawa K, Takasu N. Effects of a single administration of acarbose on postprandial glucose excursion and endothelial dysfunction in type 2 diabetic patients: a randomized crossover study. J Clin Endocrinol Metab 2006; 91: 837-42.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 837-842
    • Shimabukuro, M.1    Higa, N.2    Chinen, I.3    Yamakawa, K.4    Takasu, N.5
  • 82
    • 4444302990 scopus 로고    scopus 로고
    • Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NFkappaB activation in PBMCs
    • Rudofsky G Jr, Reismann P, Schiekofer S, et al.Reduction of postprandial hyperglycemia in patients with type 2 diabetes reduces NFkappaB activation in PBMCs. Horm Metab Res 2004; 36(9): 630-8.
    • (2004) Horm Metab Res , vol.36 , Issue.9 , pp. 630-638
    • Rudofsky, G.1    Reismann, P.2    Schiekofer, S.3
  • 83
  • 84
    • 0033592101 scopus 로고    scopus 로고
    • Glucose tolerance and mortality: Comparison of WHO and American Diabetes Association diagnostic criteria. Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Europe
    • European Diabetes Epidemiology Group
    • The DECODE Study group. European Diabetes Epidemiology Group. Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Europe. Lancet 1999; 354(9179): 617-21.
    • (1999) Lancet , vol.354 , Issue.9179 , pp. 617-621
  • 85
    • 0041666333 scopus 로고    scopus 로고
    • Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases?
    • European Diabetes Epidemiology Group
    • DECODE Study Group, European Diabetes Epidemiology Group. Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases? Diabetes Care 2003; 26(3): 688-96.
    • (2003) Diabetes Care , vol.26 , Issue.3 , pp. 688-696
  • 86
    • 78649912825 scopus 로고    scopus 로고
    • Cardiovascular disease mortality in Europeans in relation to fasting and 2-h plasma glucose levels within a normoglycemic range
    • Ning F, Tuomilehto J, Pyörälä K, Onat A, Söderberg S, Qiao Q; DECODE Study Group. Cardiovascular disease mortality in Europeans in relation to fasting and 2-h plasma glucose levels within a normoglycemic range. Diabetes Care 2010; 33(10): 2211-6.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2211-2216
    • Ning, F.1    Tuomilehto, J.2    Pyörälä, K.3    Onat, A.4    Söderberg, S.5    Qiao, Q.6
  • 88
    • 0032775825 scopus 로고    scopus 로고
    • Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: The Hoorn Study
    • de Vegt F, Dekker JM, Ruhé HG, Stehouwer CD, Nijpels G, Bouter LM, Heine RJ. Hyperglycaemia is associated with all-cause and cardiovascular mortality in the Hoorn population: the Hoorn Study. Diabetologia 1999; 42: 926-31.
    • (1999) Diabetologia , vol.42 , pp. 926-931
    • De Vegt, F.1    Dekker, J.M.2    Ruhé, H.G.3    Stehouwer, C.D.4    Nijpels, G.5    Bouter, L.M.6    Heine, R.J.7
  • 89
    • 0032820409 scopus 로고    scopus 로고
    • Isolated post-challenge hyperglycaemia confirmed as a risk factor for mortality
    • Shaw JE Hodge AM, de Courten M, Chitson P, Zimmet PZ. Isolated post-challenge hyperglycaemia confirmed as a risk factor for mortality. Diabetologia 1999; 42: 1050-54.
    • (1999) Diabetologia , vol.42 , pp. 1050-1054
    • Shaw Je Hodge, A.M.1    De Courten, M.2    Chitson, P.3    Zimmet, P.Z.4
  • 90
    • 84884958712 scopus 로고    scopus 로고
    • Effect of acarbose to delay progression of carotid intima-media thickness in early diabetes
    • Patel YR, Kirkman MS, Considine RV, Hannon TS, Mather KJ. Effect of acarbose to delay progression of carotid intima-media thickness in early diabetes. Diabetes Metab Res Rev 2013; 29(7): 582-91.
    • (2013) Diabetes Metab Res Rev , vol.29 , Issue.7 , pp. 582-591
    • Patel, Y.R.1    Kirkman, M.S.2    Considine, R.V.3    Hannon, T.S.4    Mather, K.J.5
  • 91
    • 79951941643 scopus 로고    scopus 로고
    • Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes
    • Su G, Mi S, Tao H, Li Z, Yang H, Zheng H, Zhou Y, Ma C. Association of glycemic variability and the presence and severity of coronary artery disease in patients with type 2 diabetes. Cardiovasc Diabetol 2011; 10: 19.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 19
    • Su, G.1    Mi, S.2    Tao, H.3    Li, Z.4    Yang, H.5    Zheng, H.6    Zhou, Y.7    Ma, C.8
  • 93
    • 84879391645 scopus 로고    scopus 로고
    • The GLP-1 receptor agonist liraglutide inhibits progression of vascular disease via effects on atherogenesis, plaque stability and endothelial function in an ApoE(-/-) mouse model
    • Gaspari T, Welungoda I, Widdop RE, Simpson RW, Dear AE. The GLP-1 receptor agonist liraglutide inhibits progression of vascular disease via effects on atherogenesis, plaque stability and endothelial function in an ApoE(-/-) mouse model. Diab Vasc Dis Res 2013; 10(4): 353-60.
    • (2013) Diab Vasc Dis Res , vol.10 , Issue.4 , pp. 353-360
    • Gaspari, T.1    Welungoda, I.2    Widdop, R.E.3    Simpson, R.W.4    Dear, A.E.5
  • 94
    • 80051785333 scopus 로고    scopus 로고
    • DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice
    • Ta NN, Schuyler CA, Li Y, Lopes-Virella MF, Huang Y. DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 2011; 58(2): 157-66.
    • (2011) J Cardiovasc Pharmacol , vol.58 , Issue.2 , pp. 157-166
    • Ta, N.N.1    Schuyler, C.A.2    Li, Y.3    Lopes-Virella, M.F.4    Huang, Y.5
  • 97
    • 84881507403 scopus 로고    scopus 로고
    • Preventive effect of dipeptidyl peptidase-4 inhibitor on atherosclerosis is mainly attributable to incretin's actions in nondiabetic and diabetic apolipoprotein E-null mice
    • Terasaki M, Nagashima M, Nohtomi K, Kohashi K, Tomoyasu M, Sinmura K, Nogi Y, Katayama Y, Sato K, Itoh F, Watanabe T, Hirano T. Preventive effect of dipeptidyl peptidase-4 inhibitor on atherosclerosis is mainly attributable to incretin's actions in nondiabetic and diabetic apolipoprotein E-null mice PLoS One 2013; 8(8): e70933.
    • (2013) Plos One , vol.8 , Issue.8
    • Terasaki, M.1    Nagashima, M.2    Nohtomi, K.3    Kohashi, K.4    Tomoyasu, M.5    Sinmura, K.6    Nogi, Y.7    Katayama, Y.8    Sato, K.9    Itoh, F.10    Watanabe, T.11    Hirano, T.12
  • 98
    • 11844269899 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines
    • Nikolaidis LA, Doverspike A, Hentosz T, Zourelias L, Shen YT, Elahi D, Shannon RP. Glucagon-like peptide-1 limits myocardial stunning following brief coronary occlusion and reperfusion in conscious canines. J Pharmacol Exp Ther 2005; 312(1): 303-8.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.1 , pp. 303-308
    • Nikolaidis, L.A.1    Doverspike, A.2    Hentosz, T.3    Zourelias, L.4    Shen, Y.T.5    Elahi, D.6    Shannon, R.P.7
  • 100
    • 80052072913 scopus 로고    scopus 로고
    • Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: Evidence for improving cardiac metabolic efficiency
    • Bao W, Aravindhan K, Alsaid H, Chendrimada T, Szapacs M, Citerone DR, Harpel MR, Willette RN, Lepore JJ, Jucker BM. Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency. PLoS One 2011; 6(8)
    • (2011) Plos One , vol.6 , Issue.8
    • Bao, W.1    Aravindhan, K.2    Alsaid, H.3    Chendrimada, T.4    Szapacs, M.5    Citerone, D.R.6    Harpel, M.R.7    Willette, R.N.8    Lepore, J.J.9    Jucker, B.M.10
  • 101
    • 12144260853 scopus 로고    scopus 로고
    • Glucagon- like peptide 1 can directly protect the heart against ischemia/ reperfusion injury
    • Mocanu MM, Carr RD, Brand CL, Yellon DM. Glucagon- like peptide 1 can directly protect the heart against ischemia/ reperfusion injury. Diabetes 2005; 54(1): 146-51.
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 146-151
    • Mocanu, M.M.1    Carr, R.D.2    Brand, C.L.3    Yellon, D.M.4
  • 102
    • 4344605042 scopus 로고    scopus 로고
    • Recombinant glucagon- like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacinginduced dilated cardiomyopathy
    • Nikolaidis LA, Elahi D, Hentosz T, Doverspike A, Huerbin R, Zourelias L, Stolarski C, Shen YT, Shannon RP. Recombinant glucagon- like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacinginduced dilated cardiomyopathy. Circulation 2004; 110(8): 955-61.
    • (2004) Circulation , vol.110 , Issue.8 , pp. 955-961
    • Nikolaidis, L.A.1    Elahi, D.2    Hentosz, T.3    Doverspike, A.4    Huerbin, R.5    Zourelias, L.6    Stolarski, C.7    Shen, Y.T.8    Shannon, R.P.9
  • 103
    • 58949102483 scopus 로고    scopus 로고
    • Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat
    • Poornima I, Brown SB, Bhashyam S, Parikh P, Bolukoglu H, Shannon RP. Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat. Circ Heart Fail 2008; 1(3): 153-60.
    • (2008) Circ Heart Fail , vol.1 , Issue.3 , pp. 153-160
    • Poornima, I.1    Brown, S.B.2    Bhashyam, S.3    Parikh, P.4    Bolukoglu, H.5    Shannon, R.P.6
  • 105
    • 84873554686 scopus 로고    scopus 로고
    • Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: Systematic review and meta-analysis
    • Robinson LE, Holt TA, Rees K, Randeva HS, O'Hare JP. Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis. BMJ Open 2013; 24; 3(1).
    • (2013) BMJ Open , vol.3 , Issue.1
    • Robinson, L.E.1    Holt, T.A.2    Rees, K.3    Randeva, H.S.4    O'hare, J.P.5
  • 106
    • 84879800350 scopus 로고    scopus 로고
    • Blood pressure-lowering effects of GLP-1 receptor agonists exenatide and liraglutide: A meta-analysis of clinical trials
    • Wang B, Zhong J, Lin H, Zhao Z, Yan Z, He H, Ni Y, Liu D, Zhu Z. Blood pressure-lowering effects of GLP-1 receptor agonists exenatide and liraglutide: a meta-analysis of clinical trials. Diabetes Obes Metab 2013; 15(8): 737-49.
    • (2013) Diabetes Obes Metab , vol.15 , Issue.8 , pp. 737-749
    • Wang, B.1    Zhong, J.2    Lin, H.3    Zhao, Z.4    Yan, Z.5    He, H.6    Ni, Y.7    Liu, D.8    Zhu, Z.9
  • 107
    • 84890536384 scopus 로고    scopus 로고
    • Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: Results of a systematic meta-analysis and meta-regression
    • Katout M, Zhu H, Rutsky J, Shah P, Brook RD, Zhong J, Rajagopalan S. Effect of GLP-1 mimetics on blood pressure and relationship to weight loss and glycemia lowering: results of a systematic meta-analysis and meta-regression. Am J Hypertens 2014; 27(1): 130-9.
    • (2014) Am J Hypertens , vol.27 , Issue.1 , pp. 130-139
    • Katout, M.1    Zhu, H.2    Rutsky, J.3    Shah, P.4    Brook, R.D.5    Zhong, J.6    Rajagopalan, S.7
  • 108
    • 84875054251 scopus 로고    scopus 로고
    • Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors
    • Barbieri M, Rizzo MR, Marfella R, Boccardi V, Esposito A, Pansini A, Paolisso G. Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors. Atherosclerosis 2013; 227(2): 349-54.
    • (2013) Atherosclerosis , vol.227 , Issue.2 , pp. 349-354
    • Barbieri, M.1    Rizzo, M.R.2    Marfella, R.3    Boccardi, V.4    Esposito, A.5    Pansini, A.6    Paolisso, G.7
  • 109
    • 84895762544 scopus 로고    scopus 로고
    • Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study
    • Rizzo M, Chandalia M, Patti AM, Di Bartolo V, Rizvi AA, Montalto G, Abate N. Liraglutide decreases carotid intima-media thickness in patients with type 2 diabetes: 8-month prospective pilot study. Cardiovasc Diabetol 2014; 13(1): 49.
    • (2014) Cardiovasc Diabetol , vol.13 , Issue.1
    • Rizzo, M.1    Chandalia, M.2    Patti, A.M.3    Di Bartolo, V.4    Rizvi, A.A.5    Montalto, G.6    Abate, N.7
  • 110
    • 84857111888 scopus 로고    scopus 로고
    • Cardioprotection against ischaemia induced by dobutamine stress using glucagon-like peptide-1 in patients with coronary artery disease
    • Read PA, Khan FZ, Dutka DP. Cardioprotection against ischaemia induced by dobutamine stress using glucagon-like peptide-1 in patients with coronary artery disease. Heart 2012; 98(5): 408-1.
    • (2012) Heart , vol.98 , Issue.5 , pp. 408-411
    • Read, P.A.1    Khan, F.Z.2    Dutka, D.P.3
  • 111
    • 1442311383 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion
    • Nikolaidis LA, Mankad S, Sokos GG, Miske G, Shah A, Elahi D, Shannon RP. Effects of glucagon-like peptide-1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 2004; 109(8): 962-5.
    • (2004) Circulation , vol.109 , Issue.8 , pp. 962-965
    • Nikolaidis, L.A.1    Mankad, S.2    Sokos, G.G.3    Miske, G.4    Shah, A.5    Elahi, D.6    Shannon, R.P.7
  • 112
    • 84860390563 scopus 로고    scopus 로고
    • A pilot study to assess whether glucagon-like peptide-1 protects the heart from ischemic dysfunction and attenuates stunning after coronary balloon occlusion in humans
    • Read PA, Hoole SP, White PA, Khan FZ, O'Sullivan M, West NE, Dutka DP. A pilot study to assess whether glucagon-like peptide-1 protects the heart from ischemic dysfunction and attenuates stunning after coronary balloon occlusion in humans. Circ Cardiovasc Interv 2011; 4(3): 266-272.
    • (2011) Circ Cardiovasc Interv , vol.4 , Issue.3 , pp. 266-272
    • Read, P.A.1    Hoole, S.P.2    White, P.A.3    Khan, F.Z.4    O'sullivan, M.5    West, N.E.6    Dutka, D.P.7
  • 116
    • 84883295202 scopus 로고    scopus 로고
    • Cardioprotective effects of exenatide in patients with STsegment- elevation myocardial infarction undergoing primary percutaneous coronary intervention: Results of exenatide myocardial protection in revascularization study
    • Woo JS, Kim W, Ha SJ, Kim JB, Kim SJ, Kim WS, Seon HJ, Kim KS. Cardioprotective effects of exenatide in patients with STsegment- elevation myocardial infarction undergoing primary percutaneous coronary intervention: results of exenatide myocardial protection in revascularization study. Arterioscler Thromb Vasc Biol 2013; 33(9): 2252-60.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.9 , pp. 2252-2260
    • Woo, J.S.1    Kim, W.2    Ha, S.J.3    Kim, J.B.4    Kim, S.J.5    Kim, W.S.6    Seon, H.J.7    Kim, K.S.8
  • 118
    • 33845293219 scopus 로고    scopus 로고
    • Glucagon- like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure
    • Sokos GG, Nikolaidis LA, Mankad S, Elahi D, Shannon RP. Glucagon- like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J Card Fail 2006; 12(9): 694-9.
    • (2006) J Card Fail , vol.12 , Issue.9 , pp. 694-699
    • Sokos, G.G.1    Nikolaidis, L.A.2    Mankad, S.3    Elahi, D.4    Shannon, R.P.5
  • 119
    • 84862521094 scopus 로고    scopus 로고
    • Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: A double-blind, randomised controlled clinical trial of efficacy and safety
    • Nathanson D, Ullman B, Löfström U, Hedman A, Frick M, Sjöholm A, Nyström T. Effects of intravenous exenatide in type 2 diabetic patients with congestive heart failure: a double-blind, randomised controlled clinical trial of efficacy and safety. Diabetologia 2012; 55(4): 926-35.
    • (2012) Diabetologia , vol.55 , Issue.4 , pp. 926-935
    • Nathanson, D.1    Ullman, B.2    Löfström, U.3    Hedman, A.4    Frick, M.5    Sjöholm, A.6    Nyström, T.7
  • 121
    • 84878939138 scopus 로고    scopus 로고
    • Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus
    • White WB, Pratley R, Fleck P, Munsaka M, Hisada M, Wilson C, Menon V. Cardiovascular safety of the dipetidyl peptidase-4 inhibitor alogliptin in type 2 diabetes mellitus. Diabetes Obes Metab 2013; 15(7): 668-73.
    • (2013) Diabetes Obes Metab , vol.15 , Issue.7 , pp. 668-673
    • White, W.B.1    Pratley, R.2    Fleck, P.3    Munsaka, M.4    Hisada, M.5    Wilson, C.6    Menon, V.7
  • 125
    • 84893200919 scopus 로고    scopus 로고
    • Assessment of the cardiovascular safety of saxagliptin in patients with type 2 diabetes mellitus: Pooled analysis of 20 clinical trials
    • Iqbal N, Parker A, Frederich R, Donovan M, Hirshberg B. Assessment of the cardiovascular safety of saxagliptin in patients with type 2 diabetes mellitus: pooled analysis of 20 clinical trials. Cardiovasc Diabetol 2014; 13: 33.
    • (2014) Cardiovasc Diabetol , vol.13
    • Iqbal, N.1    Parker, A.2    Frederich, R.3    Donovan, M.4    Hirshberg, B.5
  • 128
    • 77950880269 scopus 로고    scopus 로고
    • Dipeptydil peptidase-4 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
    • Monami M, Iacomelli I, Marchionni N, Mannucci E. Dipeptydil peptidase-4 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis 2010; 20(4): 224-35.
    • (2010) Nutr Metab Cardiovasc Dis , vol.20 , Issue.4 , pp. 224-235
    • Monami, M.1    Iacomelli, I.2    Marchionni, N.3    Mannucci, E.4
  • 129
    • 77953182696 scopus 로고    scopus 로고
    • Assessing the cardio-cerebrovascular safety of vildagliptin: Meta-analysis of adjudicated events from a large Phase III type 2 diabetes population
    • Schweizer A, Dejager S, Foley JE, Couturier A, Ligueros-Saylan M, Kothny W. Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large Phase III type 2 diabetes population. Diabetes Obes Metab 2010; 12(6): 485-94.
    • (2010) Diabetes Obes Metab , vol.12 , Issue.6 , pp. 485-494
    • Schweizer, A.1    Dejager, S.2    Foley, J.E.3    Couturier, A.4    Ligueros-Saylan, M.5    Kothny, W.6
  • 130
    • 81855194761 scopus 로고    scopus 로고
    • Safety of dipeptidyl peptidase-4 inhibitors: A meta-analysis of randomized clinical trials
    • Monami M, Dicembrini I, Martelli D, Mannucci E. Safety of dipeptidyl peptidase-4 inhibitors: a meta-analysis of randomized clinical trials. Curr Med Res Opin 2011; 27 Suppl 3: 57-64.
    • (2011) Curr Med Res Opin , vol.27 , pp. 57-64
    • Monami, M.1    Dicembrini, I.2    Martelli, D.3    Mannucci, E.4
  • 131
    • 84865492997 scopus 로고    scopus 로고
    • Meta-analysis of effect of dipeptidyl peptidase-4 inhibitors on cardiovascular risk in type 2 diabetes mellitus
    • Patil HR, Al Badarin FJ, Al Shami HA, Bhatti SK, Lavie CJ, Bell DS, O'Keefe JH. Meta-analysis of effect of dipeptidyl peptidase-4 inhibitors on cardiovascular risk in type 2 diabetes mellitus. Am J Cardiol 2012; 110(6): 826-33.
    • (2012) Am J Cardiol , vol.110 , Issue.6 , pp. 826-833
    • Patil, H.R.1    Al Badarin, F.J.2    Al Shami, H.A.3    Bhatti, S.K.4    Lavie, C.J.5    Bell, D.S.6    O'keefe, J.H.7
  • 132
    • 84855481995 scopus 로고    scopus 로고
    • Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: A pre-specified, prospective, and adjudicated metaanalysis of a phase 3 programme
    • Johansen OE, Neubacher D, von Eynatten M, Patel S, Woerle HJ. Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: A pre-specified, prospective, and adjudicated metaanalysis of a phase 3 programme. Cardiovasc Diabetol 2012; 11: 3.
    • (2012) Cardiovasc Diabetol , vol.11
    • Johansen, O.E.1    Neubacher, D.2    Von Eynatten, M.3    Patel, S.4    Woerle, H.J.5
  • 133
    • 84904007147 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: Meta-analysis of randomized clinical trials with 55,141 participants
    • Wu S, Hopper I, Skiba M, Krum H. Dipeptidyl peptidase-4 inhibitors and cardiovascular outcomes: meta-analysis of randomized clinical trials with 55,141 participants. Cardiovasc Ther 2014; 32(4): 147-58.
    • (2014) Cardiovasc Ther , vol.32 , Issue.4 , pp. 147-158
    • Wu, S.1    Hopper, I.2    Skiba, M.3    Krum, H.4
  • 134
    • 84895467669 scopus 로고    scopus 로고
    • Head-to-head comparison of dipeptidyl peptidase-IV inhibitors and sulfonylureas - a meta-analysis from randomized clinical trials
    • Zhang Y, Hong J, Chi J, Gu W, Ning G, Wang W. Head-to-head comparison of dipeptidyl peptidase-IV inhibitors and sulfonylureas - a meta-analysis from randomized clinical trials. Diabetes Metab Res Rev 2014; 30(3): 241-56.
    • (2014) Diabetes Metab Res Rev , vol.30 , Issue.3 , pp. 241-256
    • Zhang, Y.1    Hong, J.2    Chi, J.3    Gu, W.4    Ning, G.5    Wang, W.6
  • 135
    • 84890568491 scopus 로고    scopus 로고
    • Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: A metaanalysis
    • Wu D, Li L, Liu C. Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a metaanalysis. Diabetes Obes Metab 2014; 16(1): 30-7.
    • (2014) Diabetes Obes Metab , vol.16 , Issue.1 , pp. 30-37
    • Wu, D.1    Li, L.2    Liu, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.