The role of dipeptidyl peptidase IV in the cleavage of glucagon family peptides: In vivo metabolism of pituitary adenylate cyclase-activating polypeptide-(1-38)

Journal of Biological Chemistry

Volumn 278, Issue 25, 2003, Pages 22418-22423

  Zhu, Lan ^a   Tamvakopoulos, Constantin ^a   Xie, Dan ^a   Dragovic, Jasminka ^a   Shen, Xiaolan ^a   Fenyk Melody, Judith E ^a   Schmidt, Keith ^a   Bagchi, Ansuman ^a   Griffin, Patrick R ^a,b   Thornberry, Nancy A ^a   Roy, Ranabir Sinha ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b ExSAR Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; GROWTH KINETICS; HORMONES; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY;

GROWTH REGULATORS (GR);

ENZYME KINETICS;

DIPEPTIDYL PEPTIDASE IV; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE; GROWTH HORMONE DERIVATIVE; GROWTH HORMONE[1-43]; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; OXYNTOMODULIN; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; CARBOHYDRATE METABOLISM; ENZYME ASSAY; ENZYME DEFICIENCY; ENZYME KINETICS; ENZYME SUBSTRATE; LIPID METABOLISM; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN METABOLISM; TANDEM MASS SPECTROMETRY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD26; CALIBRATION; GLUCAGON; HORMONES; KINETICS; MASS SPECTROMETRY; MICE; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 0037928769     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212355200     Document Type: Article

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