Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, P38 MAPK, and JNK pathways

Journal of Molecular Endocrinology

Volumn 50, Issue 2, 2013, Pages 229-241

  Erdogdu, Özlem ^a   Eriksson, Linnéa ^a   Xu, Hua ^b   Sjoholm, Åke ^a   Zhang, Qimin ^a   Nyström, Thomas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NINGXIA MEDICAL UNIVERSITY   (China)

Author keywords

Endothelial nitric oxide synthase; Exendin 4; GLP1; Human coronary endothelial cells; Lipoapoptosis

Indexed keywords

CASPASE 3; CELL DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTERY ENDOTHELIUM; ARTICLE; CELL PROTECTION; CELL STIMULATION; CORONARY ARTERY; CULTURE MEDIUM; DNA FRAGMENTATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPOAPOPTOSIS; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASE 3; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA FRAGMENTATION; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GLUCAGON-LIKE PEPTIDE 1; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE TYPE III; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PALMITATES; PEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; RECEPTORS, GLUCAGON; SIGNAL TRANSDUCTION; VENOMS;

EID: 84875348947     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-12-0166     Document Type: Article

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