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Volumn 9, Issue 15, 2010, Pages 3035-3044

Deciphering the chromatin landscape induced around DNA double strand breaks

Author keywords

AsiSI; ChIP chip; ChIP seq; Chromatin; DSB repair; H2AX

Indexed keywords

4 HYDROXYTAMOXIFEN; DOUBLE STRANDED DNA; ESTROGEN RECEPTOR; HISTONE GAMMA H2AX; HISTONE H2AX; UNCLASSIFIED DRUG;

EID: 77956803702     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.15.12412     Document Type: Review
Times cited : (48)

References (44)
  • 1
    • 85011938840 scopus 로고    scopus 로고
    • High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome
    • Iacovoni JS, Caron P, Lassadi I, Nicolas E, Massip L, Trouche D, et al. High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome. EMBO J.
    • EMBO J
    • Iacovoni, J.S.1    Caron, P.2    Lassadi, I.3    Nicolas, E.4    Massip, L.5    Trouche, D.6
  • 2
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 1999; 146:905-16.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 3
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998; 273:5858-68.
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 4
    • 33646106590 scopus 로고    scopus 로고
    • gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
    • (Amst)
    • Stucki M, Jackson SP. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair (Amst) 2006; 5:534-43.
    • (2006) DNA Repair , vol.5 , pp. 534-543
    • Stucki, M.1    Jackson, S.P.2
  • 6
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward IM, Minn K, Jorda KG, Chen J. Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J Biol Chem 2003; 278:19579-82.
    • (2003) J Biol Chem , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 10
    • 63249124451 scopus 로고    scopus 로고
    • Chromatin remodeling finds its place in the DNA double-strand break response
    • Pandita TK, Richardson C. Chromatin remodeling finds its place in the DNA double-strand break response. Nucleic Acids Res 2009; 37:1363-77.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1363-1377
    • Pandita, T.K.1    Richardson, C.2
  • 11
    • 65149084552 scopus 로고    scopus 로고
    • Crosstalk between histone modifications during the DNA damage response
    • van Attikum H, Gasser SM. Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol 2009; 19:207-17.
    • (2009) Trends Cell Biol , vol.19 , pp. 207-217
    • Van Attikum, H.1    Gasser, S.M.2
  • 12
    • 44449136965 scopus 로고    scopus 로고
    • HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response
    • Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR. HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. Nature 2008; 453:682-6.
    • (2008) Nature , vol.453 , pp. 682-686
    • Ayoub, N.1    Jeyasekharan, A.D.2    Bernal, J.A.3    Venkitaraman, A.R.4
  • 13
    • 47349107760 scopus 로고    scopus 로고
    • ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
    • Goodarzi AA, Noon AT, Deckbar D, Ziv Y, Shiloh Y, Lobrich M, et al. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol Cell 2008; 31:167-77.
    • (2008) Mol Cell , vol.31 , pp. 167-177
    • Goodarzi, A.A.1    Noon, A.T.2    Deckbar, D.3    Ziv, Y.4    Shiloh, Y.5    Lobrich, M.6
  • 14
    • 33646269070 scopus 로고    scopus 로고
    • Recruitment of the type B histone acetyltransferase Hat1p to chromatin is linked to DNA double-strand breaks
    • Qin S, Parthun MR. Recruitment of the type B histone acetyltransferase Hat1p to chromatin is linked to DNA double-strand breaks. Mol Cell Biol 2006; 26:3649-58.
    • (2006) Mol Cell Biol , vol.26 , pp. 3649-3658
    • Qin, S.1    Parthun, M.R.2
  • 15
    • 20344364883 scopus 로고    scopus 로고
    • Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair
    • Tamburini BA, Tyler JK. Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair. Mol Cell Biol 2005; 25:4903-13.
    • (2005) Mol Cell Biol , vol.25 , pp. 4903-4913
    • Tamburini, B.A.1    Tyler, J.K.2
  • 16
    • 10944267160 scopus 로고    scopus 로고
    • Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites
    • Downs JA, Allard S, Jobin-Robitaille O, Javaheri A, Auger A, Bouchard N, et al. Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol Cell 2004; 16:979-90.
    • (2004) Mol Cell , vol.16 , pp. 979-990
    • Downs, J.A.1    Allard, S.2    Jobin-Robitaille, O.3    Javaheri, A.4    Auger, A.5    Bouchard, N.6
  • 17
    • 85011940595 scopus 로고    scopus 로고
    • A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair
    • Lee HS, Park JH, Kim SJ, Kwon SJ, Kwon J. A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repair. EMBO J.
    • EMBO J
    • Lee, H.S.1    Park, J.H.2    Kim, S.J.3    Kwon, S.J.4    Kwon, J.5
  • 18
    • 70449518412 scopus 로고    scopus 로고
    • Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
    • Sun Y, Jiang X, Xu Y, Ayrapetov MK, Moreau LA, Whetstine JR, et al. Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. Nat Cell Biol 2009; 11:1376-82.
    • (2009) Nat Cell Biol , vol.11 , pp. 1376-1382
    • Sun, Y.1    Jiang, X.2    Xu, Y.3    Ayrapetov, M.K.4    Moreau, L.A.5    Whetstine, J.R.6
  • 19
    • 27844607415 scopus 로고    scopus 로고
    • Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae
    • Tsukuda T, Fleming AB, Nickoloff JA, Osley MA. Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae. Nature 2005; 438:379-83.
    • (2005) Nature , vol.438 , pp. 379-383
    • Tsukuda, T.1    Fleming, A.B.2    Nickoloff, J.A.3    Osley, M.A.4
  • 20
    • 10944233962 scopus 로고    scopus 로고
    • Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
    • van Attikum H, Fritsch O, Hohn B, Gasser SM. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell 2004; 119:777-88.
    • (2004) Cell , vol.119 , pp. 777-788
    • Van Attikum, H.1    Fritsch, O.2    Hohn, B.3    Gasser, S.M.4
  • 21
    • 15444373985 scopus 로고    scopus 로고
    • The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1
    • Giannattasio M, Lazzaro F, Plevani P, Muzi-Falconi M. The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J Biol Chem 2005; 280:9879-86.
    • (2005) J Biol Chem , vol.280 , pp. 9879-9886
    • Giannattasio, M.1    Lazzaro, F.2    Plevani, P.3    Muzi-Falconi, M.4
  • 22
    • 36248966246 scopus 로고    scopus 로고
    • RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
    • Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, Lukas C, et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007; 131:887-900.
    • (2007) Cell , vol.131 , pp. 887-900
    • Mailand, N.1    Bekker-Jensen, S.2    Faustrup, H.3    Melander, F.4    Bartek, J.5    Lukas, C.6
  • 23
    • 59049103900 scopus 로고    scopus 로고
    • The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
    • Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, et al. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009; 136:420-34.
    • (2009) Cell , vol.136 , pp. 420-434
    • Stewart, G.S.1    Panier, S.2    Townsend, K.3    Al-Hakim, A.K.4    Kolas, N.K.5    Miller, E.S.6
  • 24
    • 72449175818 scopus 로고    scopus 로고
    • Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
    • Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 2009; 462:935-9.
    • (2009) Nature , vol.462 , pp. 935-939
    • Galanty, Y.1    Belotserkovskaya, R.2    Coates, J.3    Polo, S.4    Miller, K.M.5    Jackson, S.P.6
  • 25
    • 36249031962 scopus 로고    scopus 로고
    • RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
    • Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, et al. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007; 131:901-14.
    • (2007) Cell , vol.131 , pp. 901-914
    • Huen, M.S.1    Grant, R.2    Manke, I.3    Minn, K.4    Yu, X.5    Yaffe, M.B.6
  • 28
    • 75549087964 scopus 로고    scopus 로고
    • The ubiquitin landscape at DNA double-strand breaks
    • Messick TE, Greenberg RA. The ubiquitin landscape at DNA double-strand breaks. J Cell Biol 2009; 187:319-26.
    • (2009) J Cell Biol , vol.187 , pp. 319-326
    • Messick, T.E.1    Greenberg, R.A.2
  • 29
    • 63049101044 scopus 로고    scopus 로고
    • Regulatory ubiquitylation in response to DNA double-strand breaks
    • (Amst)
    • Panier S, Durocher D. Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst) 2009; 8:436-43.
    • (2009) DNA Repair , vol.8 , pp. 436-443
    • Panier, S.1    Durocher, D.2
  • 30
    • 34447551681 scopus 로고    scopus 로고
    • Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
    • Berkovich E, Monnat RJ Jr, Kastan MB. Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol 2007; 9:683-90.
    • (2007) Nat Cell Biol , vol.9 , pp. 683-690
    • Berkovich, E.1    Monnat Jr., R.J.2    Kastan, M.B.3
  • 31
    • 0028237305 scopus 로고    scopus 로고
    • Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
    • Rouet P, Smih F, Jasin M. Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc Natl Acad Sci USA 1994; 91:6064-8.
    • Proc Natl Acad Sci USA 1994 , vol.91 , pp. 6064-6068
    • Rouet, P.1    Smih, F.2    Jasin, M.3
  • 32
    • 0028013486 scopus 로고
    • Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events
    • Kramer KM, Brock JA, Bloom K, Moore JK, Haber JE. Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination events. Mol Cell Biol 1994; 14:1293-301.
    • (1994) Mol Cell Biol , vol.14 , pp. 1293-1301
    • Kramer, K.M.1    Brock, J.A.2    Bloom, K.3    Moore, J.K.4    Haber, J.E.5
  • 33
    • 0042626553 scopus 로고    scopus 로고
    • Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast
    • Wolner B, van Komen S, Sung P, Peterson CL. Recruitment of the recombinational repair machinery to a DNA double-strand break in yeast. Mol Cell 2003; 12:221-32.
    • (2003) Mol Cell , vol.12 , pp. 221-232
    • Wolner, B.1    Van Komen, S.2    Sung, P.3    Peterson, C.L.4
  • 34
    • 0033612287 scopus 로고    scopus 로고
    • Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
    • Martin SG, Laroche T, Suka N, Grunstein M, Gasser SM. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 1999; 97:621-33.
    • (1999) Cell , vol.97 , pp. 621-633
    • Martin, S.G.1    Laroche, T.2    Suka, N.3    Grunstein, M.4    Gasser, S.M.5
  • 35
    • 34447532525 scopus 로고    scopus 로고
    • Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals
    • Kim JA, Kruhlak M, Dotiwala F, Nussenzweig A, Haber JE. Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals. J Cell Biol 2007; 178:209-18.
    • (2007) J Cell Biol , vol.178 , pp. 209-218
    • Kim, J.A.1    Kruhlak, M.2    Dotiwala, F.3    Nussenzweig, A.4    Haber, J.E.5
  • 36
    • 1542609299 scopus 로고    scopus 로고
    • Analysis of recombinational repair of DNA double-strand breaks in mammalian cells with I-SceI nuclease
    • Nickoloff JA, Brenneman MA. Analysis of recombinational repair of DNA double-strand breaks in mammalian cells with I-SceI nuclease. Methods Mol Biol 2004; 262:35-52.
    • (2004) Methods Mol Biol , vol.262 , pp. 35-52
    • Nickoloff, J.A.1    Brenneman, M.A.2
  • 37
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 38
    • 30344444484 scopus 로고    scopus 로고
    • Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
    • Murr R, Loizou JI, Yang YG, Cuenin C, Li H, Wang ZQ, et al. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat Cell Biol 2006; 8:91-9.
    • (2006) Nat Cell Biol , vol.8 , pp. 91-99
    • Murr, R.1    Loizou, J.I.2    Yang, Y.G.3    Cuenin, C.4    Li, H.5    Wang, Z.Q.6
  • 40
    • 0348149148 scopus 로고    scopus 로고
    • Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint
    • Kuhne C, Tjornhammar ML, Pongor S, Banks L, Simoncsits A. Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint. Nucleic Acids Res 2003; 31:7227-37.
    • (2003) Nucleic Acids Res , vol.31 , pp. 7227-7237
    • Kuhne, C.1    Tjornhammar, M.L.2    Pongor, S.3    Banks, L.4    Simoncsits, A.5
  • 41
    • 17644384427 scopus 로고    scopus 로고
    • Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
    • Chen BP, Chan DW, Kobayashi J, Burma S, Asaithamby A, Morotomi-Yano K, et al. Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem 2005; 280:14709-15.
    • (2005) J Biol Chem , vol.280 , pp. 14709-14715
    • Chen, B.P.1    Chan, D.W.2    Kobayashi, J.3    Burma, S.4    Asaithamby, A.5    Morotomi-Yano, K.6
  • 42
    • 0036153467 scopus 로고    scopus 로고
    • Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: Colocalization with proteins involved in DNA repair
    • Jakob B, Scholz M, Taucher-Scholz G. Characterization of CDKN1A (p21) binding to sites of heavy-ion-induced damage: colocalization with proteins involved in DNA repair. Int J Radiat Biol 2002; 78:75-88.
    • (2002) Int J Radiat Biol , vol.78 , pp. 75-88
    • Jakob, B.1    Scholz, M.2    Taucher-Scholz, G.3
  • 43
    • 4544281398 scopus 로고    scopus 로고
    • Choreography of the DNA damage response: Spatio-temporal relationships among checkpoint and repair proteins
    • Lisby M, Barlow JH, Burgess RC, Rothstein R. Choreography of the DNA damage response: spatio-temporal relationships among checkpoint and repair proteins. Cell 2004; 118:699-713.
    • (2004) Cell , vol.118 , pp. 699-713
    • Lisby, M.1    Barlow, J.H.2    Burgess, R.C.3    Rothstein, R.4
  • 44
    • 0034980594 scopus 로고    scopus 로고
    • Determination of 8-oxoguanine in individual cell nucleus of gamma-irradiated mammalian cells
    • Chen SK, Tsai MH, Hwang JJ, Chang WP. Determination of 8-oxoguanine in individual cell nucleus of gamma-irradiated mammalian cells. Radiat Res 2001; 155:832-6.
    • (2001) Radiat Res , vol.155 , pp. 832-836
    • Chen, S.K.1    Tsai, M.H.2    Hwang, J.J.3    Chang, W.P.4


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