Simultaneous determination of atorvastatin, metformin and glimepiride in human plasma by LC-MS/MS and its application to a human pharmacokinetic study

Journal of Pharmaceutical Analysis

Volumn 3, Issue 1, 2013, Pages 9-19

  Polagani, Srinivasa Rao ^a,b   Pilli, Nageswara Rao ^b   Gajula, Ramakrishna ^b   Gandu, Venkateswarlu ^c  

^a RAYALASEEMA UNIVERSITY   (India)

^b Wellquest Clinical Research   (India)

^c OSMANIA UNIVERSITY   (India)

Author keywords

Atorvastatin; Glimepiride; Human plasma; LC MS MS; Metformin; Pharmacokinetics

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; ATORVASTATIN; CARBAMAZEPINE; GLIMEPIRIDE; METFORMIN;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DILUTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG ISOLATION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; TANDEM MASS SPECTROMETRY;

EID: 84925835424     PISSN: 20951779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpha.2012.09.002     Document Type: Article

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