Simultaneous estimation of atorvastatin and its two metabolites from human plasma by ESI-LC-MS/MS

Drug Testing and Analysis

Volumn 3, Issue 6, 2011, Pages 352-362

  Ghosh, Chinmoy ^a   Jain, Ina ^a   Gaur, Shashank ^a   Patel, Niraj ^a   Upadhyay, Anita ^a   Chakraborty, Bhaswat S ^a  

^a Cadila Pharmaceuticals Limited   (India)

Author keywords

Atorvastatin; Matrix effects; O hydroxy atorvastatin; P hydroxy atorvastatin; Positional isomer; Solid phase extraction

Indexed keywords

EXTRACTION; MASS SPECTROMETRY; PHASE SEPARATION; PLASMA (HUMAN);

ATORVASTATIN; HUMAN PLASMAS; MATRICES EFFECT; O-HYDROXY; O-HYDROXY ATORVASTATIN; P-HYDROXY ATORVASTATIN; POSITIONAL ISOMERS; SOLID-PHASE EXTRACTION;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ATORVASTATIN; DRUG METABOLITE;

ARTICLE; BIOEQUIVALENCE; CALIBRATION; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIMIT OF QUANTITATION; PLASMA; PRIORITY JOURNAL; REPRODUCIBILITY; SEPARATION TECHNIQUE; SINGLE DRUG DOSE; SOLID PHASE EXTRACTION; STANDARD; TABLET;

EID: 79959536892     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.228     Document Type: Article

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