Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: Application to pharmacokinetic studies

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 308-316

  Marques, Marlice A Sípoli ^a,b   Soares, Alcenir de Souza ^a   Pinto, Olivia Woyames ^a   Barroso, Pedro Tupinambá Werneck ^a   Pinto, Douglas Pereira ^a   Ferreira Filho, Milton ^a   Werneck Barroso, Eduardo ^a  

^a Funda??o Oswaldo Cruz   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Liquid chromatography; Mass spectrometry; Metformin; Pharmacokinetic; Plasma

Indexed keywords

DEPROTEINIZATION; INTERNAL STANDARD; METFORMIN; METOPROLOL;

ACETONITRILE; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN);

PROTEINS;

ACETONITRILE; ATENOLOL; BUFORMIN; DIPHENHYDRAMINE; FORMIC ACID; GLIFAGE; METFORMIN; METOPROLOL; PHENFORMIN; RANITIDINE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 34249744487     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.01.030     Document Type: Article

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