Local immunotherapy via delivery of interleukin-10 and transforming growth factor β antagonist for treatment of chronic kidney disease

Journal of Controlled Release

Volumn 206, Issue , 2015, Pages 131-139

  Rodell, Christopher B ^a   Rai, Reena ^a   Faubel, Sarah ^b   Burdick, Jason A ^a   Soranno, Danielle E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Anti transforming growth factor ; Chronic kidney disease; Drug delivery; Hydrogel; Immunotherapy; Interleukin 10

Indexed keywords

CELL DEATH; DISEASE CONTROL; DRUG DELIVERY; ENZYME INHIBITION; EROSION; HYALURONIC ACID; HYDROGELS; MACROPHAGES; MOLECULES; SHEAR THINNING; TISSUE;

CHRONIC KIDNEY DISEASE; GUEST-HOST INTERACTIONS; IMMUNOTHERAPY; INTERLEUKIN-10; MACROPHAGE INFILTRATIONS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTORS; UNILATERAL URETERAL OBSTRUCTIONS;

DISEASES;

ANTIFIBROTIC AGENT; HYALURONIC ACID; INTERLEUKIN 10; TRANSFORMING GROWTH FACTOR BETA ANTAGONIST; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; DELAYED RELEASE FORMULATION; HYDROGEL; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL INFILTRATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DEGRADATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; FLUORESCENCE IMAGING; HISTOLOGY; HYDROGEL; IMMUNOTHERAPY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; URETER OBSTRUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CHEMISTRY; COMPLICATION; DELAYED RELEASE FORMULATION; FIBROSIS; HUMAN; KIDNEY; PATHOLOGY; RENAL INSUFFICIENCY, CHRONIC;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; FIBROSIS; HUMANS; HYALURONIC ACID; HYDROGELS; IMMUNOTHERAPY; INTERLEUKIN-10; KIDNEY; MICE; MICE, INBRED BALB C; RENAL INSUFFICIENCY, CHRONIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 84925725505     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.03.025     Document Type: Article

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