Functional evaluation of primary renal cell/biomaterial neo-kidney augment prototypes for renal tissue engineering

Cell Transplantation

Volumn 20, Issue 11-12, 2011, Pages 1771-1790

  Basu, Joydeep ^a   Genheimer, Christopher W ^a   Rivera, Elias A ^a   Payne, Richard ^a   Mihalko, Kim ^b   Guthrie, Kelly ^a   Bruce, Andrew T ^a   Robbins, Neil ^a   McCoy, Darell ^a   Sangha, Namrata ^a   Ilagan, Roger ^a   Knight, Toyin ^a   Spencer, Thomas ^a   Wagner, Belinda J ^a   Jayo, Manuel J ^a   Jain, Deepak ^a   Ludlow, John W ^a   Halberstadt, Craig ^a  

^a Tengion Inc   (United States)

^b CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Biomaterials; Kidney; Neo kidney augment; Regeneration; Renal tissue engineering

Indexed keywords

BIOMATERIAL; GELATIN; HYALURONIC ACID; POLYCAPROLACTONE; POLYGLACTIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; ARTIFICIAL KIDNEY; BIOMICS; CELL POPULATION; CONFOCAL IMMUNOFLUORESCENCE; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FUNCTIONAL ASSESSMENT; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOFLUORESCENCE; IN VITRO MATURATION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; NEOKIDNEY AUGMENT; NEOVASCULARIZATION (PATHOLOGY); PHENOTYPE; PRIORITY JOURNAL; PROTEOMICS; SECRETOMICS; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TRANSCRIPTOMICS;

ANIMALS; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; DOGS; EPITHELIAL-MESENCHYMAL TRANSITION; GELATIN; GENE EXPRESSION PROFILING; HUMANS; HYDROGELS; KIDNEY; LACTIC ACID; POLYGLYCOLIC ACID; PROTEOME; RATS; RATS, INBRED LEW; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA;

MAMMALIA; RODENTIA;

EID: 80054052569     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368911X566172     Document Type: Article

References (43)

1. Aboushwareb, T.; Egydio, F.; Straker, L.; Gyabaah, K.; Atala, A.; Yoo, J. J. Erythropoietin producing cells for potential cell therapy. World J. Urol. 26(4):295-300; 2008.
2. Anand, A.; Pundir, R.; Pandian, C. S.; Saraf, S.; Gupta, H. Cefoperazone sodium impregnated polycaprolactone composite implant for osteomyelitis. Indian J. Pharm. Sci. 71(4):377-381; 2009.
3. Basu, J.; Genheimer, C.; Delo O'Reilly, D.; Sangha, N.; Guthrie, K.; Bertram, T. A.; Ludlow, J. W.; Jain, D. Distribution and analysis of stem and progenitor cell populations in large mammal and human kidneys. FASEB J. 24: LB35; 2010.
4. Basu, J.; Ludlow, J. W. Platform technologies for tubular organ regeneration. Trends Biotechnol. 28(10):526-533; 2010.
5. Bible, E.; Chau, D. Y.; Alexander, M. R.; Price, J.; Shake-sheff, K. M.; Modo, M. The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles. Biomaterials 30(16):2985-2994; 2009.
6. Bjugstad, K. B.; Redmond, D. E.; Lampe, K. J.; Kern, D. S.; Sladek, J. R.; Mahoney, M. J. Biocompatibility of PEG-based hydrogels in primate brain. Cell Transplant. 17(4):409-415; 2008.
7. Border, W. A.; Noble, N. A. Transforming growth factor beta in tissue fibrosis. N. Engl. J. Med. 331(19):1286-292; 1994.
8. Caplan, A. I. Why are MSCs therapeutic? New data: New insight. J. Pathol. 217(2):318-324; 2009.
9. Dudas, P. L.; Argentieri, R. L.; Farrell, F. X. BMP-7 fails to attenuate TGF-beta1-induced epithelial-to-mesenchy-mal transition in human proximal tubule epithelial cells. Nephrol. Dial. Transplant. 24(5):1406-1416; 2009.
10. Dwyer, R. M.; Potter-Beirne, S. M.; Harrington, K. A.; Lowery, A. J.; Hennessy, E.; Murphy, J. M.; Barry, F. P.; O'Brien, T.; Kerin, M. J. Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells. Clin. Cancer Res. 13(17): 5020-5027; 2007.
11. Guo, J. K.; Cantley, L. G. Cellular maintenance and repair of the kidney. Annu. Rev. Physiol. 72:357-376; 2010.
12. Halberstadt, C.; Austin, C.; Rowley, J.; Culberson, C.; Loebsack, A.; Wyatt, S.; Coleman, S.; Blacksten, L.; Burg, K.; Mooney, D.; Holder, W. A hydrogel material for plastic and reconstructive applications injected into the subcutaneous space of a sheep. Tissue Eng. 8(2):309-319; 2002.
13. Hills, C. E.; Al-Rasheed, N.; Willars, G. B.; Brunskill, N. J. C-peptide reverses TGF-beta1-induced changes in renal proximal tubular cells: Implications for treatment of diabetic nephropathy. Am. J. Physiol. Renal Physiol. 296(3):F614-621; 2009.
14. Hunt, N. C.; Grover, L. M. Cell encapsulation using bio-polymer gels for regenerative medicine. Biotechnol. Lett. 32(6):733-742; 2010.
15. Jayo, M. J.; Jain, D.; Ludlow, J. W.; Payne, R.; Wagner, B. J.; McLorie, G.; Bertram, T. A. Long-term durability, tissue regeneration and neo-organ growth during skeletal maturation with a neo-bladder augmentation construct. Regen. Med. 3(5):671-682; 2008.
16. Jayo, M. J.; Jain, D.; Wagner, B. J.; Bertram, T. A. Early cellular and stromal responses in the regeneration of a functional mammalian bladder. J. Urol. 180(1):392-397; 2008.
17. Kelley, R.; Werdin, E. S.; Bruce, A. T.; Choudhury, S.; Wallace, S. M.; Ilagan, R. M.; Cox, B. R.; Tatsumi-Ficht, P.; Rivera, E. A.; Spencer, T.; Rapoport, S. H.; Wagner, B. J.; Guthrie, K.; Jayo, M. J.; Bertram, T. A.; Presnell, S. C. A tubular cell-enriched subpopulation of primary renal cells improves survival and augments kidney function in a rodent model of chronic kidney disease. Am. J. Phys-iol. Renal. Physiol. 299(5):F1026-F1039; 2010.
18. Li, W. J.; Chiang, H.; Kuo, T. F.; Lee, H. S.; Jiang, C. C.; Tuan, R. S. Evaluation of articular cartilage repair using biodegradable nanofibrous scaffolds in a swine model: A pilot study. J. Tissue Eng. Regen. Med. 3(1):1-10; 2009.
19. Lim, S. M.; Lee, H. J.; Oh, S. H.; Kim, J. M.; Lee, J. H. Novel fabrication of PCL porous beads for use as an injectable cell carrier system. J. Biomed. Mater. Res. B Appl. Biomater. 90(2):521-530; 2009.
20. Lin, F.; Moran, A.; Igarashi, P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J. Clin. Invest. 115(7):1756-1764; 2005.
21. Loebsack, A.; Greene, K.; Wyatt, S.; Culberson, C.; Austin, C.; Beiler, R.; Roland, W.; Eiselt, P.; Rowley, J.; Burg, K.; Mooney, D.; Holder, W.; Halberstadt, C. In vivo characterization of a porous hydrogel material for use as a tissue bulking agent. J. Biomed. Mater. Res. 57(4):575-581; 2001.
22. Low, S. W.; Ng, Y. J.; Yeo, T. T.; Chou, N. Use of Os-teoplug polycaprolactone implants as novel burr-hole covers. Singapore Med. J. 50(8):777-780; 2009.
23. Lu, J. M.; Wang, X.; Marin-Muller, C.; Wang, H.; Lin, P. H.; Yao, Q.; Chen, C. Current advances in research and clinical applications of PLGA-based nanotechnology. Expert Rev. Mol. Diagn. 9(4):325-341; 2009.
24. Martens, T. P.; Godier, A. F. G.; Parks, J. J.; Wan, L. Q.; Koeckert, M. S.; Eng, G. M.; Hudson, B. I.; Sherman, W.; Vunjak-Novakovic, G. Percutaneous cell delivery into the heart using hydrogels polymerizing in situ. Cell Transplant. 18(3):297-304; 2009.
25. Natarajan, V.; Krithica, N.; Madhan, B.; Sehgal, P. K. Formulation and evaluation of quercetin polycaprolactone microspheres for the treatment of rheumatoid arthritis. J. Pharm. Sci. 100(1):195-205; 2011.
26. Okada, H.; Inoue, T.; Suzuki, H.; Strutz, F.; Neilson, E. G. Epithelial-mesenchymal transformation of renal tubular epithelial cells in vitro and in vivo. Nephrol. Dial. Transplant. 15(Suppl. 6):44-46; 2000.
27. Pektok, E.; Nottelet, B.; Tille, J. C.; Gurny, R.; Kalangos, A.; Moeller, M.; Walpoth, B. H. Degradation and healing characteristics of small-diameter poly(epsilon-caprolac-tone) vascular grafts in the rat systemic arterial circulation. Circulation 118(24):2563-2570; 2008.
28. Powe, N. R.; Plantinga, L.; Saran, R. Public health surveillance of CKD: Principles, steps, and challenges. Am. J. Kidney Dis. 53(3 Suppl. 3):S37-45; 2009.
29. Presnell, S. C.; Bruce, A. T.; Wallace, S. M.; Choudhury, S.; Genheimer, C. W.; Cox, B.; Guthrie, K.; Werdin, E. S.; Tatsumi-Ficht, P.; Ilagan, R. M.; Kelley, R. W.; Rivera, E. A.; Ludlow, J. W.; Wagner, B. J.; Jayo, M. J.; Bertram, T. A. Isolation, characterization and expansion methods for defined primary renal cell populations from rodent, canine and human normal and diseased kidneys. Tissue Eng. Part C Methods 17(3):261-273; 2011.
30. Prophet, E. B.; Mills, B.; Arrington, J. B.; Sobin, L. H. Armed Forces Institute of Pathology: Laboratory methods in histotechnology. Washington, DC: American Registry of Pathology; 1992.
31. Rai, B.; Lin, J. L.; Lim, Z. X.; Guldberg, R. E.; Hutmacher, D. W.; Cool, S. M. Differences between in vitro viability and differentiation and in vivo bone-forming efficacy of human mesenchymal stem cells cultured on PCL-TCP scaffolds. Biomaterials 31(31):7960-7970; 2010.
32. Rosines, E.; Schmidt, H. J.; Nigam, S. K. The effect of hyaluronic acid size and concentration on branching morphogenesis and tubule differentiation in developing kidney culture systems: Potential applications to engineering of renal tissues. Biomaterials 28(32):4806-4817; 2007.
33. Shackelford, C.; Long, G.; Wolf, J.; Okerberg, C.; Herbert, R. Qualitative and quantitative analysis of non-neoplastic lesions in toxicology studies. Toxicol. Pathol. 30(1):93-96; 2002.
34. Silva-Cunha, A.; Fialho, S. L.; Naud, M. C.; Behar-Cohen, F. Poly-epsilon-caprolactone intravitreous devices: An in vivo study. Invest. Ophthalmol. Vis. Sci. 50(5): 2312-2318; 2009.
35. Stephan, S.; Ball, S. G.; Williamson, M.; Bax, D. V.; Lomas, A.; Shuttleworth, C. A.; Kielty, C. M. Cell-matrix biology in vascular tissue engineering. J. Anat. 209(4): 495-502; 2006.
36. Suggs, L. J.; Mikos, A. G. Synthetic biodegradable polymers for medical applications. In: Mark, J. E., ed. Physical properties of polymers handbook. Melville, NY: American Institute of Physics; 1996:615-624.
37. Tate, S. S.; Meister, A. Gamma-Glutamyl transpeptidase from kidney. Methods Enzymol. 113:400-419; 1985.
38. U.S. Renal Data System. Costs of CKD and ESRD. In: U.S. renal data system. 2007 USRDS annual data report. Minneapolis, MN: U.S. Renal Data System; 2007:223-238.
39. Vidal, B. C.; Bonventre, J. V.; I-Hong Hsu, S. Towards the application of proteomics in renal disease diagnosis. Clin. Sci. (Lond.) 109(5):421-430; 2005.
40. Vize, P. D.; Woolf, A. S.; Bard, J. B. L. The kidney: From normal development to congenital disease, 1st ed. London: Academic Press; 2003.
41. Wong, D. Y.; Krebsbach, P. H.; Hollister, S. J. Brain cortex regeneration affected by scaffold architectures. J. Neu-rosurg. 109(4):715-722; 2008.
42. Xu, F.; Shi, J.; Yu, B.; Ni, W.; Wu, X.; Gu, Z. Chemo-kines mediate mesenchymal stem cell migration toward gliomas in vitro. Oncol. Rep. 23(6):1561-1567; 2010.
43. Zeisberg, M.; Maeshima, Y.; Mosterman, B.; Kalluri, R. Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am. J. Pathol. 160(6):2001-2008; 2002.