NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response

Biochemistry

Volumn 53, Issue 37, 2014, Pages 5895-5906

  Rizzo, Alessandro A ^a   Salerno, Paige E ^a   Bezsonova, Irina ^a   Korzhnev, Dmitry M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CHEMICAL SHIFT; DAMAGE TOLERANCE; DNA; ENZYME ACTIVITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ZINC COMPOUNDS;

BINDING PROPERTIES; CELLULAR DNA DAMAGE; DNA DAMAGE RESPONSE; IDENTICAL STRUCTURES; MEDIATED INTERACTION; NMR CHEMICAL SHIFT PERTURBATIONS; NUCLEAR MAGNETIC RESONANCE (NMR); TRANSLESION SYNTHESIS;

MAGNETIC DOMAINS;

CELL DNA; DNA BINDING PROTEIN; HOMODIMER; RAD18 PROTEIN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME RAD16; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; DNA DIRECTED DNA POLYMERASE; RAD18 PROTEIN, HUMAN; ZINC FINGER PROTEIN;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CONJUGATION; DISSOCIATION CONSTANT; DNA BINDING; DNA DAMAGE; DNA SYNTHESIS; IONIZING RADIATION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; RING FINGER MOTIF; SEQUENCE ALIGNMENT; STATIC ELECTRICITY; UBIQUITINATION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

DNA DAMAGE; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; HUMANS; MODELS, MOLECULAR; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; UBIQUITIN; ZINC FINGERS;

EID: 84925716913     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500823h     Document Type: Article

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