메뉴 건너뛰기




Volumn 2015, Issue , 2015, Pages

Loss of AMP-activated protein kinase induces mitochondrial dysfunction and proinflammatory response in unstimulated Abcd1-knockout mice mixed glial cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOCHONDRIAL COMPLEX V; MITOCHONDRIAL PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCD1 PROTEIN, MOUSE; AMPK ALPHA1 SUBUNIT, MOUSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE;

EID: 84925607535     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/176983     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 84864042465 scopus 로고    scopus 로고
    • X-linked adrenoleukodystrophy: Clinical, metabolic, genetic and pathophysiological aspects
    • S. Kemp, J. Berger, and P. Aubourg, "X-linked adrenoleukodystrophy: clinical, metabolic, genetic and pathophysiological aspects," Biochimica et BiophysicaActa, vol. 1822, no. 9, pp. 1465-1474, 2012.
    • (2012) Biochimica et BiophysicaActa , vol.1822 , Issue.9 , pp. 1465-1474
    • Kemp, S.1    Berger, J.2    Aubourg, P.3
  • 2
    • 0028175513 scopus 로고
    • The protein coded by the X-adenoleukodystrophy gene is a peroxisomal integralmembrane protein
    • M. Contreras, J. Mosser, J. L. Mandel, P. Aubourg, and I. Singh, "The protein coded by the X-adenoleukodystrophy gene is a peroxisomal integralmembrane protein," FEBS Letters, vol. 344, no. 2-3, pp. 211-215, 1994.
    • (1994) FEBS Letters , vol.344 , Issue.2-3 , pp. 211-215
    • Contreras, M.1    Mosser, J.2    Mandel, J.L.3    Aubourg, P.4    Singh, I.5
  • 3
    • 84864816455 scopus 로고    scopus 로고
    • X-linked adrenoleukodystrophy (X-ALD): Clinical presentation and guidelines for diagnosis, follow-up andmanagement
    • M. Engelen, S. Kemp, M. de Visser et al., "X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up andmanagement," Orphanet Journal of Rare Diseases, vol. 7, no. 1, article 51, 2012.
    • (2012) Orphanet Journal of Rare Diseases , vol.7 , Issue.1
    • Engelen, M.1    Kemp, S.2    De Visser, M.3
  • 4
    • 77953191945 scopus 로고    scopus 로고
    • Pathomechanisms underlying Xadrenoleukodystrophy: A three-hit hypothesis
    • I. Singh and A. Pujol, "Pathomechanisms underlying Xadrenoleukodystrophy: a three-hit hypothesis," Brain Pathology, vol. 20, no. 4, pp. 838-844, 2010.
    • (2010) Brain Pathology , vol.20 , Issue.4 , pp. 838-844
    • Singh, I.1    Pujol, A.2
  • 6
    • 0031587790 scopus 로고    scopus 로고
    • Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism
    • T. Kobayashi, N. Shinnoh, A. Kondo, and T. Yamada, "Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism," Biochemical and Biophysical Research Communications, vol. 232, no. 3, pp. 631-636, 1997.
    • (1997) Biochemical and Biophysical Research Communications , vol.232 , Issue.3 , pp. 631-636
    • Kobayashi, T.1    Shinnoh, N.2    Kondo, A.3    Yamada, T.4
  • 7
    • 0030689779 scopus 로고    scopus 로고
    • Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice
    • S. Forss-Petter, H. Werner, J. Berger et al., "Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice," Journal of Neuroscience Research, vol. 50, no. 5, pp. 829-843, 1997.
    • (1997) Journal of Neuroscience Research , vol.50 , Issue.5 , pp. 829-843
    • Forss-Petter, S.1    Werner, H.2    Berger, J.3
  • 8
    • 0036501313 scopus 로고    scopus 로고
    • Late onset neurological phenotype of the X-ALD gene inactivation in mice: A mouse model for adrenomyeloneuropathy
    • A. Pujol, C. Hindelang, N. Callizot, U. Bartsch, M. Schachner, and J. L. Mandel, "Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy," HumanMolecular Genetics, vol. 11, no. 5, pp. 499-505, 2002.
    • (2002) HumanMolecular Genetics , vol.11 , Issue.5 , pp. 499-505
    • Pujol, A.1    Hindelang, C.2    Callizot, N.3    Bartsch, U.4    Schachner, M.5    Mandel, J.L.6
  • 9
    • 84896698571 scopus 로고    scopus 로고
    • Loss of AMP-activated protein kinase in X-linked adrenoleukodystrophy patient-derived fibroblasts and lymphocytes
    • J. Singh and S. Giri, "Loss of AMP-activated protein kinase in X-linked adrenoleukodystrophy patient-derived fibroblasts and lymphocytes," Biochemical and Biophysical Research Communications, vol. 445, no. 1, pp. 126-131, 2014.
    • (2014) Biochemical and Biophysical Research Communications , vol.445 , Issue.1 , pp. 126-131
    • Singh, J.1    Giri, S.2
  • 10
    • 84888794082 scopus 로고    scopus 로고
    • AMPKalpha1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling
    • K. C. Carroll, B. Viollet, and J. Suttles, "AMPKalpha1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling," Journal of Leukocyte Biology, vol. 94, no. 6, pp. 1113-1121, 2013.
    • (2013) Journal of Leukocyte Biology , vol.94 , Issue.6 , pp. 1113-1121
    • Carroll, K.C.1    Viollet, B.2    Suttles, J.3
  • 11
    • 67649229607 scopus 로고    scopus 로고
    • Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity
    • N. Nath, M. Khan, R. Rattan et al., "Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity," Biochemical and Biophysical Research Communications, vol. 386, no. 1, pp. 16-20, 2009.
    • (2009) Biochemical and Biophysical Research Communications , vol.386 , Issue.1 , pp. 16-20
    • Nath, N.1    Khan, M.2    Rattan, R.3
  • 12
    • 84872576236 scopus 로고    scopus 로고
    • Metabolism of inflammation limited by AMPK and pseudo-starvation
    • L. A. J. O'Neill and D. Grahame Hardie, "Metabolism of inflammation limited by AMPK and pseudo-starvation," Nature, vol. 493, no. 7432, pp. 346-355, 2013.
    • (2013) Nature , vol.493 , Issue.7432 , pp. 346-355
    • O'Neill, L.A.J.1    Grahame Hardie, D.2
  • 13
    • 67649196932 scopus 로고    scopus 로고
    • Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis
    • N. Nath, M. Khan, M. K. Paintlia, I. Singh, M. N. Hoda, and S. Giri, "Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis," The Journal of Immunology, vol. 182, pp. 8005-8014, 2009.
    • (2009) The Journal of Immunology , vol.182 , pp. 8005-8014
    • Nath, N.1    Khan, M.2    Paintlia, M.K.3    Singh, I.4    Hoda, M.N.5    Giri, S.6
  • 14
    • 21244437079 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide ribonucleoside: A novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis
    • N. Nath, S. Giri, R. Prasad, M. L. Salem, A. K. Singh, and I. Singh, "5-Aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis,"The Journal of Immunology, vol. 175, no. 1, pp. 566-574, 2005.
    • (2005) The Journal of Immunology , vol.175 , Issue.1 , pp. 566-574
    • Nath, N.1    Giri, S.2    Prasad, R.3    Salem, M.L.4    Singh, A.K.5    Singh, I.6
  • 15
    • 80053163909 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise
    • H. M. O'Neill, S. J. Maarbjerg, J. D. Crane et al., "AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise," Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 38, pp. 16092-16097, 2011.
    • (2011) Proceedings of the National Academy of Sciences of the United States of America , vol.108 , Issue.38 , pp. 16092-16097
    • O'Neill, H.M.1    Maarbjerg, S.J.2    Crane, J.D.3
  • 16
    • 63449100325 scopus 로고    scopus 로고
    • Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: Implication for Xadrenoleukodystrophy
    • J. Singh, M. Khan, and I. Singh, "Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for Xadrenoleukodystrophy," Journal of Lipid Research, vol. 50, no. 1, pp. 135-147, 2009.
    • (2009) Journal of Lipid Research , vol.50 , Issue.1 , pp. 135-147
    • Singh, J.1    Khan, M.2    Singh, I.3
  • 17
    • 67649229607 scopus 로고    scopus 로고
    • Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity
    • N. Nath, M. Khan, R. Rattan et al., "Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity," Biochemical and Biophysical Research Communications, vol. 386, no. 1, pp. 16-20, 2009.
    • (2009) Biochemical and Biophysical Research Communications , vol.386 , Issue.1 , pp. 16-20
    • Nath, N.1    Khan, M.2    Rattan, R.3
  • 18
    • 84055190798 scopus 로고    scopus 로고
    • Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity
    • S. Galic, M. D. Fullerton, J. D. Schertzer et al., "Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity," Journal of Clinical Investigation, vol. 121, no. 12, pp. 4903-4915, 2011.
    • (2011) Journal of Clinical Investigation , vol.121 , Issue.12 , pp. 4903-4915
    • Galic, S.1    Fullerton, M.D.2    Schertzer, J.D.3
  • 19
    • 84881356321 scopus 로고    scopus 로고
    • AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration
    • R. Mounier, M. Théret, L. Arnold et al., "AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration," Cell Metabolism, vol. 18, no. 2, pp. 251-264, 2013.
    • (2013) Cell Metabolism , vol.18 , Issue.2 , pp. 251-264
    • Mounier, R.1    Théret, M.2    Arnold, L.3
  • 20
    • 84880795860 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells
    • J. Singh, M. Khan, A. Pujol, M. Baarine, and I. Singh, "Histone deacetylase inhibitor upregulates peroxisomal fatty acid oxidation and inhibits apoptotic cell death in abcd1-deficient glial cells," PLoS ONE, vol. 8, no. 7, Article ID e70712, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.7
    • Singh, J.1    Khan, M.2    Pujol, A.3    Baarine, M.4    Singh, I.5
  • 21
    • 84895106927 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative damage cooperatively fuel axonal degeneration in X-linked adrenoleukodystrophy
    • S. Fourcade, J. López-Erauskin, M. Ruiz, I. Ferrer, and A. Pujol, "Mitochondrial dysfunction and oxidative damage cooperatively fuel axonal degeneration in X-linked adrenoleukodystrophy," Biochimie, vol. 98, no. 1, pp. 143-149, 2014.
    • (2014) Biochimie , vol.98 , Issue.1 , pp. 143-149
    • Fourcade, S.1    López-Erauskin, J.2    Ruiz, M.3    Ferrer, I.4    Pujol, A.5
  • 22
    • 84895152385 scopus 로고    scopus 로고
    • Pathophysiology of X-linked adrenoleukodystrophy
    • J. Berger, S. Forss-Petter, and F. S. Eichler, "Pathophysiology of X-linked adrenoleukodystrophy," Biochimie, vol. 98, no. 1, pp. 135-142, 2014.
    • (2014) Biochimie , vol.98 , Issue.1 , pp. 135-142
    • Berger, J.1    Forss-Petter, S.2    Eichler, F.S.3
  • 23
    • 1242269834 scopus 로고    scopus 로고
    • Respiratory chain complex v deficiency due to a mutation in the assembly gene ATP12
    • L. De Meirleir, S. Seneca, W. Lissens et al., "Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12," Journal of Medical Genetics, vol. 41, no. 2, pp. 120-124, 2004.
    • (2004) Journal of Medical Genetics , vol.41 , Issue.2 , pp. 120-124
    • De Meirleir, L.1    Seneca, S.2    Lissens, W.3
  • 24
    • 65249092667 scopus 로고    scopus 로고
    • Pathogenicmutations of nuclear genes associated with mitochondrial disorders
    • X. Zhu, X. Peng, M. X. Guan, and Q. Yan, "Pathogenicmutations of nuclear genes associated with mitochondrial disorders," Acta Biochimica et Biophysica Sinica, vol. 41, no. 3, pp. 179-187, 2009.
    • (2009) Acta Biochimica et Biophysica Sinica , vol.41 , Issue.3 , pp. 179-187
    • Zhu, X.1    Peng, X.2    Guan, M.X.3    Yan, Q.4
  • 25
    • 0033050180 scopus 로고    scopus 로고
    • Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex i
    • R. H. Triepels, L. P. van den Heuvel, J. L. C. M. Loeffen et al., "Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I," Annals of Neurology, vol. 45, no. 6, pp. 787-790, 1999.
    • (1999) Annals of Neurology , vol.45 , Issue.6 , pp. 787-790
    • Triepels, R.H.1    Heuvel Den Van, L.P.2    Loeffen, J.L.C.M.3
  • 26
    • 0033358590 scopus 로고    scopus 로고
    • Human mitochondrial complex i in health and disease
    • J. Smeitink and L. van den Heuvel, "Human mitochondrial complex I in health and disease," The American Journal of Human Genetics, vol. 64, no. 6, pp. 1505-1510, 1999.
    • (1999) The American Journal of Human Genetics , vol.64 , Issue.6 , pp. 1505-1510
    • Smeitink, J.1    Heuvel Den L.Van2
  • 27
    • 0034988212 scopus 로고    scopus 로고
    • Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes inmitochondrial complex i deficiency
    • P. Bénit, D. Chretien, N. Kadhom et al., "Large-scale deletion and point mutations of the nuclear NDUFV1 and NDUFS1 genes inmitochondrial complex I deficiency," American Journal of Human Genetics, vol. 68, no. 6, pp. 1344-1352, 2001.
    • (2001) American Journal of Human Genetics , vol.68 , Issue.6 , pp. 1344-1352
    • Bénit, P.1    Chretien, D.2    Kadhom, N.3
  • 28
    • 0029159804 scopus 로고
    • Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency
    • T. Bourgeron, P. Rustin, D. Chretien et al., "Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency," Nature Genetics, vol. 11, no. 2, pp. 144-149, 1995.
    • (1995) Nature Genetics , vol.11 , Issue.2 , pp. 144-149
    • Bourgeron, T.1    Rustin, P.2    Chretien, D.3
  • 29
    • 84877308260 scopus 로고    scopus 로고
    • A complex v ATP5A1 defect causes fatal neonatal mitochondrial encephalopathy
    • A. I. Jonckheere, G. Herma Renkema, M. Bras et al., "A complex v ATP5A1 defect causes fatal neonatal mitochondrial encephalopathy," Brain, vol. 136, no. 5, pp. 1544-1554, 2013.
    • (2013) Brain , vol.136 , Issue.5 , pp. 1544-1554
    • Jonckheere, A.I.1    Herma Renkema, G.2    Bras, M.3
  • 30
    • 79953210362 scopus 로고    scopus 로고
    • Regulation of PGC- 1alpha, a nodal regulator of mitochondrial biogenesis
    • P. J. Fernandez-Marcos and J. Auwerx, "Regulation of PGC- 1alpha, a nodal regulator of mitochondrial biogenesis," The American Journal of Clinical Nutrition, vol. 93, no. 4, pp. 884S- 890S, 2011.
    • (2011) The American Journal of Clinical Nutrition , vol.93 , Issue.4 , pp. 884S-890S
    • Fernandez-Marcos, P.J.1    Auwerx, J.2
  • 31
    • 79957960940 scopus 로고    scopus 로고
    • Metabolic control ofmitochondrial biogenesis through the PGC-1 family regulatory network
    • R. C. Scarpulla, "Metabolic control ofmitochondrial biogenesis through the PGC-1 family regulatory network," Biochimica et Biophysica Acta, vol. 1813, no. 7, pp. 1269-1278, 2011.
    • (2011) Biochimica et Biophysica Acta , vol.1813 , Issue.7 , pp. 1269-1278
    • Scarpulla, R.C.1
  • 32
    • 84908500033 scopus 로고    scopus 로고
    • Bioenergetic analysis of intact mammalian cells using the seahorse XF24 extracellular flux analyzer and a luciferase ATP assay
    • Humana Press
    • M. B. de Moura and B. van Houten, "Bioenergetic analysis of intact mammalian cells using the seahorse XF24 extracellular flux analyzer and a luciferase ATP assay," in Molecular Toxicology Protocols, vol. 1105 ofMethods inMolecular Biology, pp. 589-602, Humana Press, 2014.
    • (2014) Molecular Toxicology Protocols, Vol. 1105 OfMethods InMolecular Biology , pp. 589-602
    • De Moura, M.B.1    Van Houten, B.2
  • 34
    • 79951558626 scopus 로고    scopus 로고
    • Identification of novel SNPs of ABCD1, ABCD2, ABCD3, and ABCD4 genes in patients with X-linked adrenoleukodystrophy (ALD) based on comprehensive resequencing and association studies with ALD phenotypes
    • T. Matsukawa, M. Asheuer, Y. Takahashi et al., "Identification of novel SNPs of ABCD1, ABCD2, ABCD3, and ABCD4 genes in patients with X-linked adrenoleukodystrophy (ALD) based on comprehensive resequencing and association studies with ALD phenotypes," Neurogenetics, vol. 12, no. 1, pp. 41-50, 2011.
    • (2011) Neurogenetics , vol.12 , Issue.1 , pp. 41-50
    • Matsukawa, T.1    Asheuer, M.2    Takahashi, Y.3
  • 35
    • 63849301000 scopus 로고    scopus 로고
    • AMPK: Lessons from transgenic and knockout animals
    • (Landmark Ed)
    • B. Viollet, Y. Athea, R. Mounier et al., "AMPK: lessons from transgenic and knockout animals," Frontiers in Bioscience (Landmark Ed), vol. 14, no. 1, pp. 19-44, 2009.
    • (2009) Frontiers in Bioscience , vol.14 , Issue.1 , pp. 19-44
    • Viollet, B.1    Athea, Y.2    Mounier, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.