Attenuation of neuroinflammatory responses and behavioral deficits by Ligusticum officinale (Makino) Kitag in stimulated microglia and MPTP-induced mouse model of Parkinsons disease

Journal of Ethnopharmacology

Volumn 164, Issue , 2015, Pages 388-397

  Kim, Byung Wook ^a   Koppula, Sushruta ^a   Park, Shin Young ^a   Kim, Yon Suk ^a   Park, Pyo Jam ^a   Lim, Ji Hong ^a   Kim, In Su ^a   Choi, Dong Kug ^a  

^a Konkuk University   (South Korea)

Author keywords

Ferulic acid; Ligusticum officinale; Makino; Microglia; MPTP; Neuroinflammation; Parkinsons disease

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALCOHOL; ANTIINFLAMMATORY AGENT; FERULIC ACID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGUSTICUM OFFICINALE EXTRACT; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT EXTRACT; UNCLASSIFIED DRUG; CD11B ANTIGEN; CYCLOOXYGENASE 2; CYTOKINE; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NERVE PROTEIN; NEUROPROTECTIVE AGENT; NITRIC OXIDE; NOS2 PROTEIN, MOUSE; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BEHAVIOR CHANGE; BRADYKINESIA; BRAIN TISSUE; DRUG EFFECT; DRUG SYNTHESIS; HERB; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIGUSTICUM OFFICINALE; MALE; MICROGLIA; MOUSE; MPTP-INDUCED PARKINSONISM; NERVE CELL STIMULATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROPHYLAXIS; PROTEIN DEGRADATION; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CELL LINE; CELL SURVIVAL; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENETICS; LIGUSTICUM; METABOLISM; PARKINSONIAN DISORDERS; PHYTOTHERAPY;

CNIDIUM OFFICINALE; MUS;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANTI-INFLAMMATORY AGENTS; BEHAVIOR, ANIMAL; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOKINES; DISEASE MODELS, ANIMAL; LIGUSTICUM; MACROPHAGE-1 ANTIGEN; MALE; MICE, INBRED C57BL; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PARKINSONIAN DISORDERS; PHYTOTHERAPY; PLANT EXTRACTS; RNA, MESSENGER;

EID: 84925599968     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.11.004     Document Type: Article

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