메뉴 건너뛰기




Volumn 402, Issue 1-2, 2015, Pages 213-223

Crucial roles of canonical Runx2-dependent pathway on Wnt1-induced osteoblastic differentiation of human periodontal ligament fibroblasts

Author keywords

Human periodontal fibroblasts; Osteoblastogenesis; Runx2; Signal transduction pathway; Wnt1

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; CALCIUM; COLLAGEN TYPE 1; DICKKOPF 1 PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN SYNTHASE KINASE 3BETA; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN; OSTERIX 2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR 7; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; WNT1 PROTEIN; CTNNB1 PROTEIN, HUMAN; DKK1 PROTEIN, HUMAN; RUNX2 PROTEIN, HUMAN; SIGNAL PEPTIDE; WNT1 PROTEIN, HUMAN;

EID: 84925517804     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2329-y     Document Type: Article
Times cited : (26)

References (38)
  • 1
    • 0026163220 scopus 로고
    • Role of fibroblast subpopulations in periodontal physiology and pathology
    • COI: 1:STN:280:DyaK3MzhvVCisg%3D%3D, PID: 1830616
    • McCulloch CA, Bordin S (1991) Role of fibroblast subpopulations in periodontal physiology and pathology. J Periodontal Res 26:144–154
    • (1991) J Periodontal Res , vol.26 , pp. 144-154
    • McCulloch, C.A.1    Bordin, S.2
  • 2
    • 0020403222 scopus 로고
    • Nuclear size as a cell-kinetic marker for osteoblast differentiation
    • COI: 1:STN:280:DyaL3s7itlyhsQ%3D%3D, PID: 7158610
    • Roberts WE, Mozsary PG, Klingler E (1982) Nuclear size as a cell-kinetic marker for osteoblast differentiation. Am J Anat 165:373–384
    • (1982) Am J Anat , vol.165 , pp. 373-384
    • Roberts, W.E.1    Mozsary, P.G.2    Klingler, E.3
  • 3
    • 66149153412 scopus 로고    scopus 로고
    • Mechanical force induces type I collagen expression in human periodontal ligament fibroblasts through activation of ERK/JNK and AP-1
    • COI: 1:CAS:528:DC%2BD1MXkslCktLc%3D, PID: 19206162
    • Kook SH, Hwang JM, Park JS, Kim EM, Heo JS, Jeon YM, Lee JC (2009) Mechanical force induces type I collagen expression in human periodontal ligament fibroblasts through activation of ERK/JNK and AP-1. J Cell Biochem 106:1060–1067
    • (2009) J Cell Biochem , vol.106 , pp. 1060-1067
    • Kook, S.H.1    Hwang, J.M.2    Park, J.S.3    Kim, E.M.4    Heo, J.S.5    Jeon, Y.M.6    Lee, J.C.7
  • 4
    • 36549008617 scopus 로고    scopus 로고
    • Skeletal development-Wnts are in control
    • COI: 1:CAS:528:DC%2BD2sXht12jtLnM, PID: 17978569
    • Hartmann C (2007) Skeletal development-Wnts are in control. Mol Cells 24:177–184
    • (2007) Mol Cells , vol.24 , pp. 177-184
    • Hartmann, C.1
  • 5
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • COI: 1:CAS:528:DC%2BD2cXot1yjsbc%3D, PID: 15474285
    • Westendorf JJ, Kahler RA, Schroeder TM (2004) Wnt signaling in osteoblasts and bone diseases. Gene 341:19–39
    • (2004) Gene , vol.341 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 6
    • 33646433058 scopus 로고    scopus 로고
    • Regulation of bone mass by Wnt signaling
    • COI: 1:CAS:528:DC%2BD28XksVWgu7s%3D, PID: 16670761
    • Krishnan V, Bryant HU, Macdougald OA (2006) Regulation of bone mass by Wnt signaling. J Clin Investig 116:1202–1209
    • (2006) J Clin Investig , vol.116 , pp. 1202-1209
    • Krishnan, V.1    Bryant, H.U.2    Macdougald, O.A.3
  • 7
    • 42449109564 scopus 로고    scopus 로고
    • Wnt signaling and skeletal development
    • COI: 1:CAS:528:DC%2BD1cXlsF2rtbY%3D, PID: 18164181
    • Liu F, Kohlmeier S, Wang CY (2008) Wnt signaling and skeletal development. Cell Signal 20:999–1009
    • (2008) Cell Signal , vol.20 , pp. 999-1009
    • Liu, F.1    Kohlmeier, S.2    Wang, C.Y.3
  • 8
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: arrows point the way
    • COI: 1:CAS:528:DC%2BD2cXjvVaqtbc%3D, PID: 15084453
    • He X, Semenov M, Tamai K, Zeng X (2004) LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: arrows point the way. Development 131:1663–1677
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 9
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • COI: 1:CAS:528:DC%2BD2MXkslGisb0%3D, PID: 15686623
    • Nusse R (2005) Wnt signaling in disease and in development. Cell Res 15:28–32
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 10
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors
    • COI: 1:CAS:528:DC%2BD28XnvVSquro%3D, PID: 16793760
    • Gordon MD, Nusse R (2006) Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 281:22429–22433
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 11
    • 0036467369 scopus 로고    scopus 로고
    • The JNK signal transduction pathway
    • COI: 1:CAS:528:DC%2BD38XktFGmtg%3D%3D, PID: 11790549
    • Weston CR, Davis RJ (2002) The JNK signal transduction pathway. Curr Opin Genet Dev 12:14–21
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 14-21
    • Weston, C.R.1    Davis, R.J.2
  • 12
    • 33845981499 scopus 로고    scopus 로고
    • Wnt signaling and osteoblastogenesis
    • COI: 1:CAS:528:DC%2BD2sXht12mtQ%3D%3D
    • Bodine PV, Komm BS (2006) Wnt signaling and osteoblastogenesis. Rev Endocr Metabol Disord 7:33–39
    • (2006) Rev Endocr Metabol Disord , vol.7 , pp. 33-39
    • Bodine, P.V.1    Komm, B.S.2
  • 13
    • 22644447278 scopus 로고    scopus 로고
    • Regulation of skeletal development by the Runx family of transcription factors
    • COI: 1:CAS:528:DC%2BD2MXkslOnsrc%3D, PID: 15786491
    • Komori T (2005) Regulation of skeletal development by the Runx family of transcription factors. J Cell Biochem 95:445–453
    • (2005) J Cell Biochem , vol.95 , pp. 445-453
    • Komori, T.1
  • 14
    • 0028038329 scopus 로고
    • Alterations of the growth characteristics of the fibroblast cell line C3H 10T1/2 by members of the Wnt gene family
    • COI: 1:CAS:528:DyaK2cXlsFCnurg%3D, PID: 8058323
    • Bradbury JM, Niemeyer CC, Dale TC, Edwards PA (1994) Alterations of the growth characteristics of the fibroblast cell line C3H 10T1/2 by members of the Wnt gene family. Oncogene 9:2597–2603
    • (1994) Oncogene , vol.9 , pp. 2597-2603
    • Bradbury, J.M.1    Niemeyer, C.C.2    Dale, T.C.3    Edwards, P.A.4
  • 16
    • 33744919534 scopus 로고    scopus 로고
    • Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor
    • COI: 1:CAS:528:DC%2BD28XmtVagtb8%3D, PID: 16575901
    • Dong YF, Soung do Y, Schwarz EM, O’Keefe RJ, Drissi H (2006) Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. J Cell Physiol 208:77–86
    • (2006) J Cell Physiol , vol.208 , pp. 77-86
    • Dong, Y.F.1    Soung do, Y.2    Schwarz, E.M.3    O’Keefe, R.J.4    Drissi, H.5
  • 20
    • 78650516444 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling enhances osteoblastogenic differentiation from human periodontal ligament fibroblasts
    • COI: 1:CAS:528:DC%2BC3cXhsVyhur%2FM, PID: 20848229
    • Heo JS, Lee SY, Lee JC (2010) Wnt/β-catenin signaling enhances osteoblastogenic differentiation from human periodontal ligament fibroblasts. Mol Cells 30:449–454
    • (2010) Mol Cells , vol.30 , pp. 449-454
    • Heo, J.S.1    Lee, S.Y.2    Lee, J.C.3
  • 21
    • 84909956992 scopus 로고    scopus 로고
    • Wnt signaling regulates homeostasis of the periodontal ligament
    • COI: 1:CAS:528:DC%2BC2cXhvVyls7fI, PID: 24410666
    • Lim WH, Liu B, Cheng D, Williams BO, Mah SJ, Helms JA (2014) Wnt signaling regulates homeostasis of the periodontal ligament. J Periodontal Res 49:751–759
    • (2014) J Periodontal Res , vol.49 , pp. 751-759
    • Lim, W.H.1    Liu, B.2    Cheng, D.3    Williams, B.O.4    Mah, S.J.5    Helms, J.A.6
  • 22
    • 77956449955 scopus 로고    scopus 로고
    • Periapical follicle stem cell: a promising candidate for cementum/periodontal ligament regeneration and bio-root engineering
    • COI: 1:CAS:528:DC%2BC3cXhtFWqsbbM, PID: 19995154
    • Han C, Yang Z, Zhou W, Jin F, Song Y, Wang Y, Huo N, Chen L, Qian H, Hou R, Duan Y, Jin Y (2010) Periapical follicle stem cell: a promising candidate for cementum/periodontal ligament regeneration and bio-root engineering. Stem Cells Dev 19:1405–1415
    • (2010) Stem Cells Dev , vol.19 , pp. 1405-1415
    • Han, C.1    Yang, Z.2    Zhou, W.3    Jin, F.4    Song, Y.5    Wang, Y.6    Huo, N.7    Chen, L.8    Qian, H.9    Hou, R.10    Duan, Y.11    Jin, Y.12
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • COI: 1:CAS:528:DyaE28XksVehtrY%3D, PID: 942051
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 24
    • 40149102166 scopus 로고    scopus 로고
    • Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling
    • PID: 18292354
    • ten Dijke P, Krause C, de Gorter DJ, Lowik CW, van Bezooijen RL (2008) Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling. J Bone Joint Surg Am 90:31–35
    • (2008) J Bone Joint Surg Am , vol.90 , pp. 31-35
    • ten Dijke, P.1    Krause, C.2    de Gorter, D.J.3    Lowik, C.W.4    van Bezooijen, R.L.5
  • 25
    • 84874048317 scopus 로고    scopus 로고
    • β-catenin is required in odontoblasts for tooth root formation
    • COI: 1:CAS:528:DC%2BC2cXhs1OlsLbO, PID: 23345535
    • Kim TH, Bae CH, Lee JC, Ko SO, Yang X, Jiang R, Cho ES (2013) β-catenin is required in odontoblasts for tooth root formation. J Dent Res 92:215–221
    • (2013) J Dent Res , vol.92 , pp. 215-221
    • Kim, T.H.1    Bae, C.H.2    Lee, J.C.3    Ko, S.O.4    Yang, X.5    Jiang, R.6    Cho, E.S.7
  • 26
    • 63449121771 scopus 로고    scopus 로고
    • Wnt signaling inhibits cementoblast differentiation and promotes proliferation
    • COI: 1:CAS:528:DC%2BD1MXktFagsLo%3D, PID: 19442631
    • Nemoto E, Koshikawa Y, Kanaya S, Tsuchiya M, Tamura M, Somerman M, Shimauchi H (2009) Wnt signaling inhibits cementoblast differentiation and promotes proliferation. Bone 44:805–812
    • (2009) Bone , vol.44 , pp. 805-812
    • Nemoto, E.1    Koshikawa, Y.2    Kanaya, S.3    Tsuchiya, M.4    Tamura, M.5    Somerman, M.6    Shimauchi, H.7
  • 27
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • COI: 1:CAS:528:DC%2BD38XosF2hsg%3D%3D, PID: 11792318
    • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B (2002) The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108:17–29
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    de Crombrugghe, B.7
  • 29
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • COI: 1:CAS:528:DC%2BD2MXkslentbc%3D, PID: 15866164
    • Day TF, Guo X, Garrett-Beal L, Yang Y (2005) Wnt/β-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 8:739–750
    • (2005) Dev Cell , vol.8 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 32
    • 37249028142 scopus 로고    scopus 로고
    • Transcriptional regulation of osteoblasts
    • COI: 1:CAS:528:DC%2BD1cXitVGqtQ%3D%3D, PID: 18083928
    • Franceschi RT, Ge C, Xiao G, Roca H, Jiang D (2007) Transcriptional regulation of osteoblasts. Ann NY Acad Sci 1116:196–207
    • (2007) Ann NY Acad Sci , vol.1116 , pp. 196-207
    • Franceschi, R.T.1    Ge, C.2    Xiao, G.3    Roca, H.4    Jiang, D.5
  • 33
    • 54849424320 scopus 로고    scopus 로고
    • Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling
    • COI: 1:CAS:528:DC%2BD1cXht1elu7vE, PID: 18613030
    • Amantea CM, Kim WK, Meliton V, Tetradis S, Parhami F (2008) Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling. J Cell Biochem 105:424–436
    • (2008) J Cell Biochem , vol.105 , pp. 424-436
    • Amantea, C.M.1    Kim, W.K.2    Meliton, V.3    Tetradis, S.4    Parhami, F.5
  • 34
    • 40849083276 scopus 로고    scopus 로고
    • Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma
    • COI: 1:CAS:528:DC%2BD1cXjs1Whurk%3D, PID: 18294945
    • Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr (2008) Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma. Bone 42:669–680
    • (2008) Bone , vol.42 , pp. 669-680
    • Qiang, Y.W.1    Barlogie, B.2    Rudikoff, S.3    Shaughnessy, J.D.4
  • 36
    • 33947535118 scopus 로고    scopus 로고
    • Direct interactions of Runx2 and canonical Wnt signaling induce FGF18
    • COI: 1:CAS:528:DC%2BD2sXht1Kqsb4%3D, PID: 17158875
    • Reinhold MI, Naski MC (2007) Direct interactions of Runx2 and canonical Wnt signaling induce FGF18. J Biol Chem 282:3653–3663
    • (2007) J Biol Chem , vol.282 , pp. 3653-3663
    • Reinhold, M.I.1    Naski, M.C.2
  • 37
    • 59149102022 scopus 로고    scopus 로고
    • Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a
    • COI: 1:CAS:528:DC%2BD1MXhs1eis7s%3D, PID: 19109969
    • Zhang Z, Deb A, Pachori A, He W, Guo J, Pratt R, Dzau VJ (2009) Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a. J Mol Cell Cardiol 46:370–377
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 370-377
    • Zhang, Z.1    Deb, A.2    Pachori, A.3    He, W.4    Guo, J.5    Pratt, R.6    Dzau, V.J.7
  • 38
    • 84875338998 scopus 로고    scopus 로고
    • Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells
    • COI: 1:CAS:528:DC%2BC3sXlsVOntLo%3D, PID: 23533594
    • Liu J, Wang Y, Du W, Liu W, Liu F, Zhang L, Zhang M, Hou M, Liu K, Zhang S, Yu B (2013) Wnt1 inhibits hydrogen peroxide-induced apoptosis in mouse cardiac stem cells. PLoS One 8:e58883
    • (2013) PLoS One , vol.8 , pp. e58883
    • Liu, J.1    Wang, Y.2    Du, W.3    Liu, W.4    Liu, F.5    Zhang, L.6    Zhang, M.7    Hou, M.8    Liu, K.9    Zhang, S.10    Yu, B.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.