Lysophosphatidic acid rescues bone mesenchymal stem cells from hydrogen peroxide-induced apoptosis

Apoptosis

Volumn 20, Issue 3, 2015, Pages 273-284

  Wang, Xian Yun ^a   Fan, Xue Song ^a   Cai, Lin ^a   Liu, Si ^a   Cong, Xiang Feng ^a   Chen, Xi ^a  

^a FUWAI HOSPITAL   (China)

Author keywords

Apoptosis; Autophagy; Bone marrow mesenchymal stem cells (BMSCs); Hydrogen peroxide (H2< inf>O2< inf>); Lysophosphatidic acid (LPA)

Indexed keywords

CASPASE 3; HYDROGEN PEROXIDE; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; GNAI2 PROTEIN, RAT; GNAI3 PROTEIN, RAT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPROTEIN; LC3 PROTEIN, RAT; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL HYPOXIA; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CYTOLOGY; DRUG EFFECTS; GENETICS; MALE; MESENCHYMAL STROMA CELL; METABOLISM; PRIMARY CELL CULTURE; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BONE MARROW CELLS; CASPASE 3; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HYDROGEN PEROXIDE; LYSOPHOSPHOLIPIDS; MALE; MESENCHYMAL STROMAL CELLS; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; PRIMARY CELL CULTURE; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LYSOPHOSPHATIDIC ACID;

EID: 84925507378     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-1074-0     Document Type: Article

References (53)

1. Price MJ, Chou CC, Frantzen M, Miyamoto T, Kar S, Lee S, Shah PK, Martin BJ, Lill M, Forrester JS, Chen PS, Makkar RR (2006) Intravenous mesenchymal stem cell therapy early after reperfused acute myocardial infarction improves left ventricular function and alters electrophysiologic properties. Int J Cardiol 111(2):231-239. doi: 10.1016/j.ijcard.2005.07.036
2. Valina C, Pinkernell K, Song YH, Bai X, Sadat S, Campeau RJ, Le Jemtel TH, Alt E (2007) Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction. Eur Heart J 28(21):2667-2677. doi: 10.1093/eurheartj/ehm426
3. Geng YJ (2003) Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure. Ann NY Acad Sci 1010:687-697
4. Zhu W, Chen J, Cong X, Hu S, Chen X (2006) Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells. Stem Cells 24(2):416-425. doi: 10.1634/stemcells.2005-0121
5. Lu L, Quinn MT, Sun Y (2004) Oxidative stress in the infarcted heart: role of de novo angiotensin II production. Biochem Biophys Res Commun 325(3):943-951. doi: 10.1016/j.bbrc.2004.10.106
6. Vanden Hoek T, Becker LB, Shao ZH, Li CQ, Schumacker PT (2000) Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion. Circ Res 86(5):541-548
7. Wei H, Li Z, Hu S, Chen X, Cong X (2010) Apoptosis of mesenchymal stem cells induced by hydrogen peroxide concerns both endoplasmic reticulum stress and mitochondrial death pathway through regulation of caspases, p38 and JNK. J Cell Biochem 111(4):967-978. doi: 10.1002/jcb.22785
8. Contos JJ, Chun J (2000) Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA. Genomics 64(2):155-169. doi: 10.1006/geno.2000.6122
9. Contos JJ, Ishii I, Chun J (2000) Lysophosphatidic acid receptors. Mol Pharmacol 58(6):1188-1196
10. Kaestner L, Steffen P, Nguyen DB, Wang J, Wagner-Britz L, Jung A, Wagner C, Bernhardt I (2012) Lysophosphatidic acid induced red blood cell aggregation in vitro. Bioelectrochemistry 87:89-95. doi: 10.1016/j.bioelechem.2011.08.004
11. Tang N, Zhao Y, Feng R, Liu Y, Wang S, Wei W, Ding Q, An MS, Wen J, Li L (2013) Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts. J Cell Mol Med. doi: 10.1111/jcmm.12178
12. Anliker B, Chun J (2004) Lysophospholipid G protein-coupled receptors. J Biol Chem 279(20):20555-20558. doi: 10.1074/jbc.R400013200
13. Chen X, Yang XY, Wang ND, Ding C, Yang YJ, You ZJ, Su Q, Chen JH (2003) Serum lysophosphatidic acid concentrations measured by dot immunogold filtration assay in patients with acute myocardial infarction. Scand J Clin Lab Invest 63(7-8):497-503
14. Chen J, Baydoun AR, Xu R, Deng L, Liu X, Zhu W, Shi L, Cong X, Hu S, Chen X (2008) Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis. Stem Cells 26(1):135-145. doi: 10.1634/stemcells.2007-0098
15. Li Z, Wei H, Liu X, Hu S, Cong X, Chen X (2010) LPA rescues ER stress-associated apoptosis in hypoxia and serum deprivation-stimulated mesenchymal stem cells. J Cell Biochem 111(4):811-820. doi: 10.1002/jcb.22731
16. Swarthout JT, Walling HW (2000) Lysophosphatidic acid: receptors, signaling and survival. Cell Mol Life Sci 57(13-14):1978-1985
17. Ye X, Ishii I, Kingsbury MA, Chun J (2002) Lysophosphatidic acid as a novel cell survival/apoptotic factor. Biochim Biophys Acta 1585(2-3):108-113
18. Guan JL, Simon AK, Prescott M, Menendez JA, Liu F, Wang F, Wang C, Wolvetang E, Vazquez-Martin A, Zhang J (2013) Autophagy in stem cells. Autophagy 9(6):830-849. doi: 10.4161/auto.24132
19. Hamacher-Brady A, Brady NR, Gottlieb RA, Gustafsson AB (2006) Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart. Autophagy 2(4):307-309
20. Terman A, Gustafsson B, Brunk UT (2007) Autophagy, organelles and ageing. J Pathol 211(2):134-143. doi: 10.1002/path.2094
21. Takagi H, Matsui Y, Sadoshima J (2007) The role of autophagy in mediating cell survival and death during ischemia and reperfusion in the heart. Antioxid Redox Signal 9(9):1373-1381. doi: 10.1089/ars.2007.1689
22. Baehrecke EH (2005) Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 6(6):505-510. doi: 10.1038/nrm1666
23. Codogno P, Meijer AJ (2005) Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12(Suppl 2):1509-1518. doi: 10.1038/sj.cdd.4401751
24. Zhang Q, Yang YJ, Wang H, Dong QT, Wang TJ, Qian HY, Xu H (2012) Autophagy activation: a novel mechanism of atorvastatin to protect mesenchymal stem cells from hypoxia and serum deprivation via AMP-activated protein kinase/mammalian target of rapamycin pathway. Stem cell dev 21(8):1321-1332. doi: 10.1089/scd.2011.0684
25. Resnic FS, Wainstein M, Lee MK, Behrendt D, Wainstein RV, Ohno-Machado L, Kirshenbaum JM, Rogers CD, Popma JJ, Piana R (2003) No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention. Am Heart J 145(1):42-46. doi: 10.1067/mhj.2003.36
26. Tanaka A, Kawarabayashi T, Nishibori Y, Sano T, Nishida Y, Fukuda D, Shimada K, Yoshikawa J (2002) No-reflow phenomenon and lesion morphology in patients with acute myocardial infarction. Circulation 105(18):2148-2152
27. Hariharan N, Zhai P, Sadoshima J (2011) Oxidative stress stimulates autophagic flux during ischemia/reperfusion. Antioxid Redox Signal 14(11):2179-2190. doi: 10.1089/ars.2010.3488
28. Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A (2009) Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16(7):966-975. doi: 10.1038/cdd.2009.33
29. Urao N, McKinney RD, Fukai T, Ushio-Fukai M (2012) NADPH oxidase 2 regulates bone marrow microenvironment following hindlimb ischemia: role in reparative mobilization of progenitor cells. Stem Cell 30(5):923-934. doi: 10.1002/stem.1048
30. Nathan C, Ding A (2010) Snapshot: reactive oxygen intermediates (ROI). cell 140(6):951-951 e952. doi: 10.1016/j.cell.2010.03.008
31. Naka K, Muraguchi T, Hoshii T, Hirao A (2008) Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells. Antioxid Redox Signal 10(11):1883-1894. doi: 10.1089/ars.2008.2114
32. Fang Y, Moore BJ, Bai Q, Cook KM, Herrick EJ, Nicholl MB (2013) Hydrogen peroxide enhances radiation-induced apoptosis and inhibition of melanoma cell proliferation. Anticancer Res 33(5):1799-1807
33. Pan H, Cheng L, Yang H, Zou W, Cheng R, Hu T (2014) Lysophosphatidic acid rescues human dental pulp cells from ischemia-induced apoptosis. J Endod 40(2):217-222. doi: 10.1016/j.joen.2013.07.015
34. Deng W, Wang DA, Gosmanova E, Johnson LR, Tigyi G (2003) LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway. Am J Physiol Gastrointest Liver Physiol 284(5):G821-G829. doi: 10.1152/ajpgi.00406.2002
35. Sun Y, Kim NH, Ji L, Kim SH, Lee J, Rhee HJ (2013) Lysophosphatidic acid activates betacatenin/T cell factor signaling, which contributes to the suppression of apoptosis in H197 cells. Mol Med Rep 8(6):1729-1733. doi: 10.3892/mmr.2013.1743
36. Binder BY, Genetos DC, Leach JK (2014) Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis. Tissue Eng Part A. doi: 10.1089/ten.TEA.2013.0487
37. Chen J, Han Y, Zhu W, Ma R, Han B, Cong X, Hu S, Chen X (2006) Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts. FEBS Lett 580(19):4737-4745. doi: 10.1016/j.febslet.2006.07.061
38. Kato K, Yoshikawa K, Tanabe E, Kitayoshi M, Fukui R, Fukushima N, Tsujiuchi T (2012) Opposite roles of LPA1 and LPA3 on cell motile and invasive activities of pancreatic cancer cells. Tumour Biol 33(5):1739-1744. doi: 10.1007/s13277-012-0433-0
39. Chen RJ, Chen SU, Chou CH, Lin MC (2012) Lysophosphatidic acid receptor 2/3-mediated IL-8-dependent angiogenesis in cervical cancer cells. Int J Cancer J Int Du Cancer 131(4):789-802. doi: 10.1002/ijc.26476
40. Taghavi P, Verhoeven E, Jacobs JJ, Lambooij JP, Stortelers C, Tanger E, Moolenaar WH, van Lohuizen M (2008) In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation. Oncogene 27(54):6806-6816. doi: 10.1038/onc.2008.294
41. Okabe K, Hayashi M, Kato K, Okumura M, Fukui R, Honoki K, Fukushima N, Tsujiuchi T (2013) Lysophosphatidic acid receptor-3 increases tumorigenicity and aggressiveness of rat hepatoma RH7777 cells. Mol Carcinog 52(4):247-254. doi: 10.1002/mc.21851
42. Sautin YY, Crawford JM, Svetlov SI (2001) Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line. Am J Physiol Cell Physiol 281(6):C2010-C2019
43. Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441(7095):885-889. doi: 10.1038/nature04724
44. Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B, Sadoshima J (2007) Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 100(6):914-922. doi: 10.1161/01.RES.0000261924.76669.36
45. Nishida K, Kyoi S, Yamaguchi O, Sadoshima J, Otsu K (2009) The role of autophagy in the heart. Cell Death Differ 16(1):31-38. doi: 10.1038/cdd.2008.163
46. Wang ZV, Rothermel BA, Hill JA (2010) Autophagy in hypertensive heart disease. J Biol Chem 285(12):8509-8514. doi: 10.1074/jbc.R109.025023
47. Yan L, Vatner DE, Kim SJ, Ge H, Masurekar M, Massover WH, Yang G, Matsui Y, Sadoshima J, Vatner SF (2005) Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci USA 102(39):13807-13812. doi: 10.1073/pnas.0506843102
48. Deng X, Zhang F, Rui W, Long F, Wang L, Feng Z, Chen D, Ding W (2013) PM2.5-induced oxidative stress triggers autophagy in human lung epithelial A549 cells. Toxicol In Vitro 27(6):1762-1770. doi: 10.1016/j.tiv.2013.05.004
49. Morales CR, Pedrozo Z, Lavandero S, Hill JA (2013) Oxidative stress and autophagy in cardiovascular homeostasis. Antioxid Redox Signal. doi: 10.1089/ars.2013.5359
50. Luo Y, Zou P, Zou J, Wang J, Zhou D, Liu L (2011) Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKalpha dependent manner. Exp Gerontol 46(11):860-867. doi: 10.1016/j.exger.2011.07.005
51. Chang CL, Ho MC, Lee PH, Hsu CY, Huang WP, Lee H (2009) S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. Am J Physiol Cell Physiol 297(2):C451-C458. doi: 10.1152/ajpcell.00586.2008
52. Lavieu G, Scarlatti F, Sala G, Carpentier S, Levade T, Ghidoni R, Botti J, Codogno P (2006) Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation. J Biol Chem 281(13):8518-8527. doi: 10.1074/jbc.M506182200
53. Daido S, Kanzawa T, Yamamoto A, Takeuchi H, Kondo Y, Kondo S (2004) Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells. Cancer Res 64(12):4286-4293. doi: 10.1158/0008-5472.CAN-03-3084