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Volumn 26, Issue 1, 2008, Pages 135-145

Lysophosphatidic acid protects mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis

Author keywords

Apoptosis; Hypoxia serum deprivation; Lysophosphatidic acid; Mesenchymal stem cells; Survival

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; WORTMANNIN;

EID: 38349053358     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2007-0098     Document Type: Article
Times cited : (96)

References (56)
  • 1
    • 0029000896 scopus 로고
    • Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
    • Pereira RF, Halford KW, O'Hara MD et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci U S A 1995;92:4857-4861.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4857-4861
    • Pereira, R.F.1    Halford, K.W.2    O'Hara, M.D.3
  • 2
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts
    • Azizi SA, Stokes D, Augelli BJ et al. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts. Proc Natl Acad Sci U S A 1998;95:3908-3913.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3908-3913
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3
  • 3
    • 0035495740 scopus 로고    scopus 로고
    • Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent
    • Kohyama J, Abe H, Shimazaki T et al. Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation 2001;68:235-244.
    • (2001) Differentiation , vol.68 , pp. 235-244
    • Kohyama, J.1    Abe, H.2    Shimazaki, T.3
  • 4
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-1530.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 5
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cells in vitro
    • Makino S, Fukuda K, Miyoshi S et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest 1999;103:697-705.
    • (1999) J Clin Invest , vol.103 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 6
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS et al. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002;105:93-98.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3
  • 7
    • 0036266426 scopus 로고
    • Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects
    • discussion
    • Shake JG, Gruber PJ, Baumgartner WA et al. Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects. Ann Thorac Surg , 2002;73:1919-1925; discussion 1926.
    • (1926) Ann Thorac Surg , 2002 , vol.73 , pp. 1919-1925
    • Shake, J.G.1    Gruber, P.J.2    Baumgartner, W.A.3
  • 8
    • 33646789159 scopus 로고    scopus 로고
    • Stem cells as a source of regenerative cardiomyocytes
    • Fukuda K, Yuasa S. Stem cells as a source of regenerative cardiomyocytes. Circ Res 2006;98:1002-1013.
    • (2006) Circ Res , vol.98 , pp. 1002-1013
    • Fukuda, K.1    Yuasa, S.2
  • 9
    • 1342284231 scopus 로고    scopus 로고
    • Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure
    • Geng YJ. Molecular mechanisms for cardiovascular stem cell apoptosis and growth in the hearts with atherosclerotic coronary disease and ischemic heart failure. Ann N Y Acad Sci 2003;1010:687-697.
    • (2003) Ann N Y Acad Sci , vol.1010 , pp. 687-697
    • Geng, Y.J.1
  • 10
    • 0037199936 scopus 로고    scopus 로고
    • Importance of FADD signaling in serum deprivation- and hypoxia-induced cardiomyocyte apoptosis
    • Chao W, Shen Y, Li L et al. Importance of FADD signaling in serum deprivation- and hypoxia-induced cardiomyocyte apoptosis. J Biol Chem 2002;277:31639-31645.
    • (2002) J Biol Chem , vol.277 , pp. 31639-31645
    • Chao, W.1    Shen, Y.2    Li, L.3
  • 11
    • 0037432170 scopus 로고    scopus 로고
    • H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: Inhibition by PMA
    • Bonavita F, Stefanelli C, Giordano E et al. H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: Inhibition by PMA. FEBS Lett 2003;536:85-91.
    • (2003) FEBS Lett , vol.536 , pp. 85-91
    • Bonavita, F.1    Stefanelli, C.2    Giordano, E.3
  • 12
    • 33745954928 scopus 로고    scopus 로고
    • Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells
    • Zhu W, Chen J, Cong X et al. Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells. STEM CELLS 2006;24:416-425.
    • (2006) STEM CELLS , vol.24 , pp. 416-425
    • Zhu, W.1    Chen, J.2    Cong, X.3
  • 13
    • 0031982675 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces necrosis and apoptosis in hippocampal neurons
    • Holtsberg FW, Steiner MR, Keller JN et al. Lysophosphatidic acid induces necrosis and apoptosis in hippocampal neurons. J Neurochem 1998;70:66 -76.
    • (1998) J Neurochem , vol.70 , pp. 66-76
    • Holtsberg, F.W.1    Steiner, M.R.2    Keller, J.N.3
  • 14
    • 0035970777 scopus 로고    scopus 로고
    • Dual effects of lysophosphatidic acid on human airway smooth muscle cell proliferation and survival
    • Ediger TL, Toews ml. Dual effects of lysophosphatidic acid on human airway smooth muscle cell proliferation and survival. Biochim Biophys Acta 2001;1531:59-67.
    • (2001) Biochim Biophys Acta , vol.1531 , pp. 59-67
    • Ediger, T.L.1    ml, T.2
  • 15
    • 0035476386 scopus 로고    scopus 로고
    • Lysophosphatidic acid promotes phorbol-ester-induced apoptosis in TF-1 cells by interfering with adhesion
    • Lai JM, Lu CY, Yang-Yen HF et al. Lysophosphatidic acid promotes phorbol-ester-induced apoptosis in TF-1 cells by interfering with adhesion. Biochem J 2001;359:227-233.
    • (2001) Biochem J , vol.359 , pp. 227-233
    • Lai, J.M.1    Lu, C.Y.2    Yang-Yen, H.F.3
  • 16
    • 0034856123 scopus 로고    scopus 로고
    • The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes
    • Karliner JS, Honbo N, Summers K et al. The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes. J Mol Cell Cardiol 2001;33:1713-1717.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1713-1717
    • Karliner, J.S.1    Honbo, N.2    Summers, K.3
  • 17
    • 0037403718 scopus 로고    scopus 로고
    • LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway
    • Deng W, Wang DA, Gosmanova E et al. LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway. Am J Physiol Gastrointest Liver Physiol 2003;284:G821-829.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Deng, W.1    Wang, D.A.2    Gosmanova, E.3
  • 18
    • 15744389876 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) protects primary chronic lymphocytic leukemia cells from apoptosis through LPA receptor activation of the antiapoptotic protein AKT/PKB
    • Hu X, Haney N, Kropp D et al. Lysophosphatidic acid (LPA) protects primary chronic lymphocytic leukemia cells from apoptosis through LPA receptor activation of the antiapoptotic protein AKT/PKB. J Biol Chem 2005;280:9498 -9508.
    • (2005) J Biol Chem , vol.280 , pp. 9498-9508
    • Hu, X.1    Haney, N.2    Kropp, D.3
  • 19
    • 0034668925 scopus 로고    scopus 로고
    • Lysophosphatidic acid prevents apoptosis in fibroblasts via G (i)-protein-mediated activation of mitogen-activated protein kinase
    • Fang X, Yu S, LaPushin R, et al. Lysophosphatidic acid prevents apoptosis in fibroblasts via G (i)-protein-mediated activation of mitogen-activated protein kinase. Biochem J2000;352:135-143.
    • Biochem , vol.J2000 , Issue.352 , pp. 135-143
    • Fang, X.1    Yu, S.2    LaPushin, R.3
  • 20
    • 0033609118 scopus 로고    scopus 로고
    • Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid
    • Weiner JA, Chun J. Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid. Proc Natl Acad Sci U S A 1999;96:5233-5238.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5233-5238
    • Weiner, J.A.1    Chun, J.2
  • 21
    • 0030665658 scopus 로고    scopus 로고
    • Lysophosphatidic acid: A novel growth and survival factor for renal proximal tubular cells
    • Levine JS, Koh JS, Triaca V et al. Lysophosphatidic acid: a novel growth and survival factor for renal proximal tubular cells. Am J Physiol 1997;273:F575-585.
    • (1997) Am J Physiol , vol.273
    • Levine, J.S.1    Koh, J.S.2    Triaca, V.3
  • 22
    • 0032528851 scopus 로고    scopus 로고
    • Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway
    • Koh JS, Lieberthal W, Heydrick S et al. Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway. J Clin Invest 1998;102:716-727.
    • (1998) J Clin Invest , vol.102 , pp. 716-727
    • Koh, J.S.1    Lieberthal, W.2    Heydrick, S.3
  • 23
    • 24044433950 scopus 로고    scopus 로고
    • Lysophosphatidic acid mediates pleiotropic responses in skeletal muscle cells
    • Jean-Baptiste G, Yang Z, Khoury C et al. Lysophosphatidic acid mediates pleiotropic responses in skeletal muscle cells. Biochem Biophys Res Commun 2005;335:1155-1162.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1155-1162
    • Jean-Baptiste, G.1    Yang, Z.2    Khoury, C.3
  • 24
    • 0033558079 scopus 로고    scopus 로고
    • Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax
    • Goetzl EJ, Kong Y, Mei B. Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. J Immunol 1999;162:2049-2056.
    • (1999) J Immunol , vol.162 , pp. 2049-2056
    • Goetzl, E.J.1    Kong, Y.2    Mei, B.3
  • 25
    • 3242671309 scopus 로고    scopus 로고
    • Cell surface receptors in lysophospholipid signaling
    • Anliker B, Chun J. Cell surface receptors in lysophospholipid signaling. Semin Cell Dev Biol 2004;15:457-465.
    • (2004) Semin Cell Dev Biol , vol.15 , pp. 457-465
    • Anliker, B.1    Chun, J.2
  • 26
    • 0038152846 scopus 로고    scopus 로고
    • Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family
    • Noguchi K, Ishii S, Shimizu T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. J Biol Chem 2003;278:25600-25606.
    • (2003) J Biol Chem , vol.278 , pp. 25600-25606
    • Noguchi, K.1    Ishii, S.2    Shimizu, T.3
  • 27
    • 33747685338 scopus 로고    scopus 로고
    • GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5
    • Lee CW, Rivera R, Gardell S et al. GPR92 as a new G12/13- and Gq-coupled lysophosphatidic acid receptor that increases cAMP, LPA5 J Biol Chem 2006;281:23589-23597.
    • (2006) J Biol Chem , vol.281 , pp. 23589-23597
    • Lee, C.W.1    Rivera, R.2    Gardell, S.3
  • 28
    • 2442658976 scopus 로고    scopus 로고
    • Lysophospholipid G protein-coupled receptors
    • Anliker B, Chun J. Lysophospholipid G protein-coupled receptors. J Biol Chem 2004;279:20555-20558.
    • (2004) J Biol Chem , vol.279 , pp. 20555-20558
    • Anliker, B.1    Chun, J.2
  • 29
    • 0029781344 scopus 로고    scopus 로고
    • Peptide and lipid growth factors decrease cis-diamminedichloroplatinum-induced cell death in human ovarian cancer cells
    • Frankel A, Mills GB. Peptide and lipid growth factors decrease cis-diamminedichloroplatinum-induced cell death in human ovarian cancer cells. Clin Cancer Res 1996;2:1307-1313.
    • (1996) Clin Cancer Res , vol.2 , pp. 1307-1313
    • Frankel, A.1    Mills, G.B.2
  • 30
    • 0038660660 scopus 로고    scopus 로고
    • Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells
    • Li Y, Gonzalez MI, Meinkoth JL et al. Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells. J Biol Chem 2003;278:9585-9591.
    • (2003) J Biol Chem , vol.278 , pp. 9585-9591
    • Li, Y.1    Gonzalez, M.I.2    Meinkoth, J.L.3
  • 31
    • 0035658526 scopus 로고    scopus 로고
    • Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line
    • Sautin YY, Crawford JM, Svetlov SI. Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line. Am J Physiol Cell Physiol 2001;281:C2010-2019.
    • (2001) Am J Physiol Cell Physiol , Issue.C2010-2019 , pp. 281
    • Sautin, Y.Y.1    Crawford, J.M.2    Svetlov, S.I.3
  • 32
    • 33745952028 scopus 로고    scopus 로고
    • Growth inhibition of mesenchymal stem cells by aspirin: Involvement of the WNT/β-catenin signal pathway
    • Wang Y, Chen X, Zhu W et al. Growth inhibition of mesenchymal stem cells by aspirin: involvement of the WNT/β-catenin signal pathway. Clin Exp Pharmacol Physiol 2006;33:696-701.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 696-701
    • Wang, Y.1    Chen, X.2    Zhu, W.3
  • 33
    • 30944449455 scopus 로고    scopus 로고
    • Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells
    • Couvillon AD, Exton JH. Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells. Cell Signal 2006;18:715-728.
    • (2006) Cell Signal , vol.18 , pp. 715-728
    • Couvillon, A.D.1    Exton, J.H.2
  • 34
    • 1842815880 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho
    • Hilal-Dandan R, Means CK, Gustafsson AB et al. Lysophosphatidic acid induces hypertrophy of neonatal cardiac myocytes via activation of Gi and Rho. J Mol Cell Cardiol 2004;36:481-493.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 481-493
    • Hilal-Dandan, R.1    Means, C.K.2    Gustafsson, A.B.3
  • 35
    • 0029064990 scopus 로고
    • Lysophosphatidic acid-induced activation of protein Ser/Thr kinases in cultured rat 3Y1 fibroblasts. Possible involvement in rho p21-mediated signaling
    • Kumagai N, Morii N, Ishizaki T et al. Lysophosphatidic acid-induced activation of protein Ser/Thr kinases in cultured rat 3Y1 fibroblasts. Possible involvement in rho p21-mediated signaling. FEBS Lett 1995;366:11-16.
    • (1995) FEBS Lett , vol.366 , pp. 11-16
    • Kumagai, N.1    Morii, N.2    Ishizaki, T.3
  • 36
    • 0346024177 scopus 로고    scopus 로고
    • Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes
    • Yu N, Lariosa-Willingham KD, Lin FF et al. Characterization of lysophosphatidic acid and sphingosine-1-phosphate-mediated signal transduction in rat cortical oligodendrocytes. Glia 2004;45:17-27.
    • (2004) Glia , vol.45 , pp. 17-27
    • Yu, N.1    Lariosa-Willingham, K.D.2    Lin, F.F.3
  • 37
    • 33747043370 scopus 로고    scopus 로고
    • Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts
    • Chen J, Han Y, Zhu W et al. Specific receptor subtype mediation of LPA-induced dual effects in cardiac fibroblasts. FEBS Lett 2006;580:4737-4745.
    • (2006) FEBS Lett , vol.580 , pp. 4737-4745
    • Chen, J.1    Han, Y.2    Zhu, W.3
  • 38
    • 0034812654 scopus 로고    scopus 로고
    • Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors
    • Fischer DJ, Nusser N, Virag T et al. Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors. Mol Pharmacol 2001;60:776-784.
    • (2001) Mol Pharmacol , vol.60 , pp. 776-784
    • Fischer, D.J.1    Nusser, N.2    Virag, T.3
  • 39
    • 17944371854 scopus 로고    scopus 로고
    • Mobilized bone marrow cells repair the infarcted heart, improving function and survival
    • Orlic D, Kajstura J, Chimenti S et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci U S A 2001;98:10344-10349.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10344-10349
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 40
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi AA, Noiseux N, Kong D et al. Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 2003;9:1195-1201.
    • (2003) Nat Med , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3
  • 41
    • 0013116058 scopus 로고    scopus 로고
    • Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction
    • Saito T, Kuang JQ, Lin CC et al. Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction. J Thorac Cardiovasc Surg 2003;126:114-123.
    • (2003) J Thorac Cardiovasc Surg , vol.126 , pp. 114-123
    • Saito, T.1    Kuang, J.Q.2    Lin, C.C.3
  • 42
    • 0035497343 scopus 로고    scopus 로고
    • The coronary delivery of marrow stromal cells for myocardial regeneration: Pathophysiologic and therapeutic implications
    • Wang JS, Shum-Tim D, Chedrawy E et al. The coronary delivery of marrow stromal cells for myocardial regeneration: pathophysiologic and therapeutic implications. J Thorac Cardiovasc Surg 2001;122:699-705.
    • (2001) J Thorac Cardiovasc Surg , vol.122 , pp. 699-705
    • Wang, J.S.1    Shum-Tim, D.2    Chedrawy, E.3
  • 43
    • 1642512389 scopus 로고    scopus 로고
    • Serum lysophosphatidic acid concentrations measured by dot immunogold filtration assay in patients with acute myocardial infarction
    • Chen X, Yang XY, Wang ND et al. Serum lysophosphatidic acid concentrations measured by dot immunogold filtration assay in patients with acute myocardial infarction. Scand J Clin Lab Invest 2003;63:497-503.
    • (2003) Scand J Clin Lab Invest , vol.63 , pp. 497-503
    • Chen, X.1    Yang, X.Y.2    Wang, N.D.3
  • 44
    • 0141996371 scopus 로고    scopus 로고
    • Molecular mechanisms of lysophosphatidic acid action
    • Tigyi G, Parrill AL. Molecular mechanisms of lysophosphatidic acid action. Prog Lipid Res 2003;42:498-526.
    • (2003) Prog Lipid Res , vol.42 , pp. 498-526
    • Tigyi, G.1    Parrill, A.L.2
  • 46
    • 0037203315 scopus 로고    scopus 로고
    • Lysophosphatidic acid as a novel cell survival/apoptotic factor
    • Ye X, Ishii I, Kingsbury MA et al. Lysophosphatidic acid as a novel cell survival/apoptotic factor. Biochim Biophys Acta 2002;1585:108-113.
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 108-113
    • Ye, X.1    Ishii, I.2    Kingsbury, M.A.3
  • 47
    • 0037374562 scopus 로고    scopus 로고
    • The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: Validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer
    • Tanyi JL, Morris AJ, Wolf JK et al. The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. Cancer Res 2003;63:1073-1082.
    • (2003) Cancer Res , vol.63 , pp. 1073-1082
    • Tanyi, J.L.1    Morris, A.J.2    Wolf, J.K.3
  • 48
    • 0037031878 scopus 로고    scopus 로고
    • Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells
    • Xie Y, Gibbs TC, Mukhin YV et al. Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells. J Biol Chem 2002;277:32516- 32526.
    • (2002) J Biol Chem , vol.277 , pp. 32516-32526
    • Xie, Y.1    Gibbs, T.C.2    Mukhin, Y.V.3
  • 49
    • 0033049579 scopus 로고    scopus 로고
    • Abnormal serum lysophospholipids in multiple myeloma patients
    • Sasagawa T, Okita M, Murakami J et al. Abnormal serum lysophospholipids in multiple myeloma patients. Lipids 1999;34:17-21.
    • (1999) Lipids , vol.34 , pp. 17-21
    • Sasagawa, T.1    Okita, M.2    Murakami, J.3
  • 50
    • 0030788697 scopus 로고    scopus 로고
    • Lysophosphatidic acid as a phospholipid mediator: Pathways of synthesis
    • Gaits F, Fourcade O, Le Balle F et al. Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis. FEBS Lett 1997;410:54-58.
    • (1997) FEBS Lett , vol.410 , pp. 54-58
    • Gaits, F.1    Fourcade, O.2    Le Balle, F.3
  • 51
    • 0034551689 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
    • Fukushima N, Weiner JA, Chun J. Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology. Dev Biol 2000;228:6-18.
    • (2000) Dev Biol , vol.228 , pp. 6-18
    • Fukushima, N.1    Weiner, J.A.2    Chun, J.3
  • 52
    • 0035884770 scopus 로고    scopus 로고
    • Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling
    • Weiner JA, Fukushima N, Contos JJ et al. Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling. J Neurosci 2001;21:7069-7078.
    • (2001) J Neurosci , vol.21 , pp. 7069-7078
    • Weiner, J.A.1    Fukushima, N.2    Contos, J.J.3
  • 53
    • 0034700050 scopus 로고    scopus 로고
    • Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior
    • Contos JJ, Fukushima N, Weiner JA et al. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc Natl Acad Sci U S A 2000;97:13384-13389.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13384-13389
    • Contos, J.J.1    Fukushima, N.2    Weiner, J.A.3
  • 54
    • 0036172927 scopus 로고    scopus 로고
    • Phosphoinositol 3 kinase inhibitor, LY294002 increases bcl-2 protein and inhibits okadaic acid-induced apoptosis in Bcl-2 expressing renal epithelial cells
    • Carbott DE, Duan L, Davis MA. Phosphoinositol 3 kinase inhibitor, LY294002 increases bcl-2 protein and inhibits okadaic acid-induced apoptosis in Bcl-2 expressing renal epithelial cells Apoptosis 2002; 7:69-76.
    • (2002) Apoptosis , vol.7 , pp. 69-76
    • Carbott, D.E.1    Duan, L.2    Davis, M.A.3
  • 55
    • 34250683438 scopus 로고    scopus 로고
    • Pertussis toxin promotes macrophage survival through inhibition of acid sphingomyelinase and activation of the phosphoinositide 3-kinase/protein kinase B pathway
    • Wang SW, Parhar K, Chiu KJ et al. Pertussis toxin promotes macrophage survival through inhibition of acid sphingomyelinase and activation of the phosphoinositide 3-kinase/protein kinase B pathway. Cell Signal 2007;19:1772-1783.
    • (2007) Cell Signal , vol.19 , pp. 1772-1783
    • Wang, S.W.1    Parhar, K.2    Chiu, K.J.3
  • 56
    • 0032942657 scopus 로고    scopus 로고
    • Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate
    • Balboa MA, Balsinde J, Dillon DA et al. Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate. J Biol Chem 1999;274:522-526.
    • (1999) J Biol Chem , vol.274 , pp. 522-526
    • Balboa, M.A.1    Balsinde, J.2    Dillon, D.A.3


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