HER2-family signalling mechanisms, clinical implications and targeting in breast cancer

Breast Cancer Research and Treatment

Volumn 149, Issue 1, 2015, Pages 5-15

  Elster, N ^a   Collins, D M ^b   Toomey, S ^a   Crown, J ^b,c   Eustace, A J ^a   Hennessy, B T ^a,d  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b DUBLIN CITY UNIVERSITY   (Ireland)

^c ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^d BEAUMONT HOSPITAL   (Ireland)

Author keywords

Breast cancer; HER2; PI3 K; Trastuzumab

Indexed keywords

AFATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EVEROLIMUS; LAPATINIB; PERTUZUMAB; PHOSPHATIDYLINOSITOL 3 KINASE; TRASTUZUMAB; TRASTUZUMAB EMTANSINE; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

ADAPTIVE IMMUNITY; BREAST CANCER; BREAST CARCINOGENESIS; CANCER PROGNOSIS; CANCER RESISTANCE; CLINICAL EFFECTIVENESS; DISEASE ACTIVITY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG RESPONSE; HUMAN; IMMUNE RESPONSE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; BREAST NEOPLASMS; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; GENETICS;

ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84925462746     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3250-x     Document Type: Review

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