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Volumn 13, Issue 1, 2015, Pages

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells

Author keywords

Cell to cell communication; Diabetes; Exosomes; MicroRNAs; Pancreatic beta cells

Indexed keywords

ARGONAUTE 2 PROTEIN; CYTOKINE; MICRORNA; UNTRANSLATED RNA;

EID: 84925441485     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/s12964-015-0097-7     Document Type: Article
Times cited : (133)

References (47)
  • 1
    • 84883488437 scopus 로고    scopus 로고
    • MicroRNAs and metabolism crosstalk in energy homeostasis
    • 1:CAS:528:DC%2BC3sXhtV2rsL%2FI 23850315
    • Dumortier O, Hinault C, Van Obberghen E. MicroRNAs and metabolism crosstalk in energy homeostasis. Cell Metab. 2013;18:312-24.
    • (2013) Cell Metab , vol.18 , pp. 312-324
    • Dumortier, O.1    Hinault, C.2    Van Obberghen, E.3
  • 2
    • 84900811419 scopus 로고    scopus 로고
    • Role of non-coding RNAs in pancreatic beta-cell development and physiology
    • 1:CAS:528:DC%2BC2cXnvF2nu70%3D
    • Eliasson L, Esguerra JL. Role of non-coding RNAs in pancreatic beta-cell development and physiology. Acta Physiol (Oxf). 2014;211:273-84.
    • (2014) Acta Physiol (Oxf) , vol.211 , pp. 273-284
    • Eliasson, L.1    Esguerra, J.L.2
  • 3
    • 84865581182 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction
    • 1:CAS:528:DC%2BC38XhsFWis7nE 22928560
    • Guay C, Jacovetti C, Nesca V, Motterle A, Tugay K, Regazzi R. Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction. Diabetes Obes Metab. 2012;14 Suppl 3:12-21.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 12-21
    • Guay, C.1    Jacovetti, C.2    Nesca, V.3    Motterle, A.4    Tugay, K.5    Regazzi, R.6
  • 4
    • 84901835072 scopus 로고    scopus 로고
    • Could microRNAs contribute to the maintenance of beta cell identity?
    • 1:CAS:528:DC%2BC2cXksFWms7o%3D 24656914
    • Kaspi H, Pasvolsky R, Hornstein E. Could microRNAs contribute to the maintenance of beta cell identity? Trends Endocrinol Metab. 2014;25:285-92.
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 285-292
    • Kaspi, H.1    Pasvolsky, R.2    Hornstein, E.3
  • 5
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • 1:CAS:528:DC%2BD1MXhs1Kiuro%3D 19167326
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136:215-33.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 6
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • 1:CAS:528:DC%2BC3MXktVCjsro%3D 21383194
    • Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci U S A. 2011;108:5003-8.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3    Ruf, I.K.4    Pritchard, C.C.5    Gibson, D.F.6
  • 7
    • 69949117622 scopus 로고    scopus 로고
    • Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
    • 1:CAS:528:DC%2BD1MXhtVKrsbnJ 19684575
    • Gibbings DJ, Ciaudo C, Erhardt M, Voinnet O. Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol. 2009;11:1143-9.
    • (2009) Nat Cell Biol , vol.11 , pp. 1143-1149
    • Gibbings, D.J.1    Ciaudo, C.2    Erhardt, M.3    Voinnet, O.4
  • 8
    • 79953301730 scopus 로고    scopus 로고
    • MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
    • 1:CAS:528:DC%2BC3MXktFWjsb4%3D 21423178
    • Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol. 2011;13:423-33.
    • (2011) Nat Cell Biol , vol.13 , pp. 423-433
    • Vickers, K.C.1    Palmisano, B.T.2    Shoucri, B.M.3    Shamburek, R.D.4    Remaley, A.T.5
  • 9
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • 1:CAS:528:DC%2BD2sXmtVSmtb8%3D 17486113
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9:654-9.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 10
    • 68849129712 scopus 로고    scopus 로고
    • Membrane vesicles as conveyors of immune responses
    • 1:CAS:528:DC%2BD1MXmvVWntr0%3D 19498381
    • Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol. 2009;9:581-93.
    • (2009) Nat Rev Immunol , vol.9 , pp. 581-593
    • Thery, C.1    Ostrowski, M.2    Segura, E.3
  • 11
    • 84863199863 scopus 로고    scopus 로고
    • Get on the exosome bus with ALIX
    • 1:CAS:528:DC%2BC38XpsVSqurs%3D 22743708
    • Hurley JH, Odorizzi G. Get on the exosome bus with ALIX. Nat Cell Biol. 2012;14:654-5.
    • (2012) Nat Cell Biol , vol.14 , pp. 654-655
    • Hurley, J.H.1    Odorizzi, G.2
  • 12
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • 1:CAS:528:DC%2BD1cXisVSksLY%3D 18309083
    • Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science. 2008;319:1244-7.
    • (2008) Science , vol.319 , pp. 1244-1247
    • Trajkovic, K.1    Hsu, C.2    Chiantia, S.3    Rajendran, L.4    Wenzel, D.5    Wieland, F.6
  • 13
    • 79953136097 scopus 로고    scopus 로고
    • Rab27a and Rab27b control different steps of the exosome secretion pathway
    • 1:CAS:528:DC%2BD1MXhsFynurrK 19966785 sup pp 11-13
    • Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, et al. Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol. 2010;12:19-30. sup pp 11-13.
    • (2010) Nat Cell Biol , vol.12 , pp. 19-30
    • Ostrowski, M.1    Carmo, N.B.2    Krumeich, S.3    Fanget, I.4    Raposo, G.5    Savina, A.6
  • 15
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • 1:CAS:528:DC%2BD1cXhsVentbfI 19011622
    • Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol. 2008;10:1470-6.
    • (2008) Nat Cell Biol , vol.10 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    Van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 16
    • 59249089695 scopus 로고    scopus 로고
    • Shedding microvesicles: Artefacts no more
    • 1:CAS:528:DC%2BD1MXhs1amt7Y%3D 19144520
    • Cocucci E, Racchetti G, Meldolesi J. Shedding microvesicles: artefacts no more. Trends Cell Biol. 2009;19:43-51.
    • (2009) Trends Cell Biol , vol.19 , pp. 43-51
    • Cocucci, E.1    Racchetti, G.2    Meldolesi, J.3
  • 17
    • 77952920881 scopus 로고    scopus 로고
    • Secretory mechanisms and intercellular transfer of microRNAs in living cells
    • 1:CAS:528:DC%2BC3cXmslSnurY%3D 20353945
    • Kosaka N, Iguchi H, Yoshioka Y, Takeshita F, Matsuki Y, Ochiya T. Secretory mechanisms and intercellular transfer of microRNAs in living cells. J Biol Chem. 2010;285:17442-52.
    • (2010) J Biol Chem , vol.285 , pp. 17442-17452
    • Kosaka, N.1    Iguchi, H.2    Yoshioka, Y.3    Takeshita, F.4    Matsuki, Y.5    Ochiya, T.6
  • 19
    • 84872932538 scopus 로고    scopus 로고
    • Intercellular transport of microRNAs
    • 1:CAS:528:DC%2BC3sXht1KksLk%3D 23325475
    • Boon RA, Vickers KC. Intercellular transport of microRNAs. Arterioscler Thromb Vasc Biol. 2013;33:186-92.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 186-192
    • Boon, R.A.1    Vickers, K.C.2
  • 21
    • 84904304045 scopus 로고    scopus 로고
    • Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets
    • Figliolini F, Cantaluppi V, De Lena M, Beltramo S, Romagnoli R, Salizzoni M, et al. Isolation, characterization and potential role in beta cell-endothelium cross-talk of extracellular vesicles released from human pancreatic islets. PLoS One. 2014;9:e102521.
    • (2014) PLoS One , vol.9 , pp. 102521
    • Figliolini, F.1    Cantaluppi, V.2    De Lena, M.3    Beltramo, S.4    Romagnoli, R.5    Salizzoni, M.6
  • 22
    • 67049098565 scopus 로고    scopus 로고
    • Characterization of vesicles secreted from insulinoma NIT-1 cells
    • 1:CAS:528:DC%2BD1MXlsF2iurc%3D 19351151
    • Lee HS, Jeong J, Lee KJ. Characterization of vesicles secreted from insulinoma NIT-1 cells. J Proteome Res. 2009;8:2851-62.
    • (2009) J Proteome Res , vol.8 , pp. 2851-2862
    • Lee, H.S.1    Jeong, J.2    Lee, K.J.3
  • 23
    • 84864817826 scopus 로고    scopus 로고
    • Characterization of membrane-shed microvesicles from cytokine-stimulated beta-cells using proteomics strategies
    • Palmisano G, Jensen SS, Le Bihan MC, Laine J, McGuire JN, Pociot F, et al. Characterization of membrane-shed microvesicles from cytokine-stimulated beta-cells using proteomics strategies. Mol Cell Proteomics. 2012;11:230-43.
    • (2012) Mol Cell Proteomics , vol.11 , pp. 230-243
    • Palmisano, G.1    Jensen, S.S.2    Le Bihan, M.C.3    Laine, J.4    McGuire, J.N.5    Pociot, F.6
  • 24
    • 80051953807 scopus 로고    scopus 로고
    • Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice
    • 1:CAS:528:DC%2BC3MXpslOrt78%3D 21734072
    • Sheng H, Hassanali S, Nugent C, Wen L, Hamilton-Williams E, Dias P, et al. Insulinoma-released exosomes or microparticles are immunostimulatory and can activate autoreactive T cells spontaneously developed in nonobese diabetic mice. J Immunol. 2011;187:1591-600.
    • (2011) J Immunol , vol.187 , pp. 1591-1600
    • Sheng, H.1    Hassanali, S.2    Nugent, C.3    Wen, L.4    Hamilton-Williams, E.5    Dias, P.6
  • 25
    • 84903635335 scopus 로고    scopus 로고
    • Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect
    • 1:CAS:528:DC%2BC2cXpvVWlt7k%3D 24798654
    • Zhu Q, Kang J, Miao H, Feng Y, Xiao L, Hu Z, et al. Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect. Febs J. 2014;281:2861-70.
    • (2014) Febs J. , vol.281 , pp. 2861-2870
    • Zhu, Q.1    Kang, J.2    Miao, H.3    Feng, Y.4    Xiao, L.5    Hu, Z.6
  • 27
    • 77951158889 scopus 로고    scopus 로고
    • Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells
    • 1:CAS:528:DC%2BC3cXltFSmt7k%3D 20086228
    • Roggli E, Britan A, Gattesco S, Lin-Marq N, Abderrahmani A, Meda P, et al. Involvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells. Diabetes. 2010;59:978-86.
    • (2010) Diabetes , vol.59 , pp. 978-986
    • Roggli, E.1    Britan, A.2    Gattesco, S.3    Lin-Marq, N.4    Abderrahmani, A.5    Meda, P.6
  • 28
    • 84863228519 scopus 로고    scopus 로고
    • Changes in microRNA expression contribute to pancreatic beta-cell dysfunction in prediabetic NOD mice
    • 1:CAS:528:DC%2BC38XhtVCrs7rM 22537941
    • Roggli E, Gattesco S, Caille D, Briet C, Boitard C, Meda P, et al. Changes in microRNA expression contribute to pancreatic beta-cell dysfunction in prediabetic NOD mice. Diabetes. 2012;61:1742-51.
    • (2012) Diabetes , vol.61 , pp. 1742-1751
    • Roggli, E.1    Gattesco, S.2    Caille, D.3    Briet, C.4    Boitard, C.5    Meda, P.6
  • 29
    • 84876912041 scopus 로고    scopus 로고
    • Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b
    • 1:CAS:528:DC%2BC3sXlvFOru78%3D 23447578
    • Goldberger N, Walker RC, Kim CH, Winter S, Hunter KW. Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b. Cancer Res. 2013;73:2671-81.
    • (2013) Cancer Res , vol.73 , pp. 2671-2681
    • Goldberger, N.1    Walker, R.C.2    Kim, C.H.3    Winter, S.4    Hunter, K.W.5
  • 30
    • 58149350340 scopus 로고    scopus 로고
    • Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction
    • 1:CAS:528:DC%2BD1MXhs1Kntrg%3D 18633110
    • Lovis P, Roggli E, Laybutt DR, Gattesco S, Yang JY, Widmann C, et al. Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes. 2008;57:2728-36.
    • (2008) Diabetes , vol.57 , pp. 2728-2736
    • Lovis, P.1    Roggli, E.2    Laybutt, D.R.3    Gattesco, S.4    Yang, J.Y.5    Widmann, C.6
  • 31
    • 84876673829 scopus 로고    scopus 로고
    • MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer
    • Christensen LL, Tobiasen H, Holm A, Schepeler T, Ostenfeld MS, Thorsen K, et al. MiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancer. Int J Cancer. 2013;133:67-78.
    • (2013) Int J Cancer , vol.133 , pp. 67-78
    • Christensen, L.L.1    Tobiasen, H.2    Holm, A.3    Schepeler, T.4    Ostenfeld, M.S.5    Thorsen, K.6
  • 32
    • 84921932058 scopus 로고    scopus 로고
    • MicroRNA-146a and MicroRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting traf6 and irak1 proteins
    • 1:CAS:528:DC%2BC2MXhvVersrg%3D 25505246
    • Park H, Huang X, Lu C, Cairo MS, Zhou X. MicroRNA-146a and MicroRNA-146b regulate human dendritic cell apoptosis and cytokine production by targeting traf6 and irak1 proteins. J Biol Chem. 2015;290:2831-41.
    • (2015) J Biol Chem , vol.290 , pp. 2831-2841
    • Park, H.1    Huang, X.2    Lu, C.3    Cairo, M.S.4    Zhou, X.5
  • 33
    • 84894482297 scopus 로고    scopus 로고
    • MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells
    • 1:CAS:528:DC%2BC3sXhtVyktb%2FP 23807224
    • Zhou Y, Jiang H, Gu J, Tang Y, Shen N, Jin Y. MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells. Cell Death Dis. 2013;4:e695.
    • (2013) Cell Death Dis , vol.4 , pp. 695
    • Zhou, Y.1    Jiang, H.2    Gu, J.3    Tang, Y.4    Shen, N.5    Jin, Y.6
  • 34
    • 84875318609 scopus 로고    scopus 로고
    • MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1
    • 1:CAS:528:DC%2BC3sXotFCmsrk%3D 23531080
    • Creevey L, Ryan J, Harvey H, Bray IM, Meehan M, Khan AR, et al. MicroRNA-497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1. Mol Cancer. 2013;12:23.
    • (2013) Mol Cancer , vol.12 , pp. 23
    • Creevey, L.1    Ryan, J.2    Harvey, H.3    Bray, I.M.4    Meehan, M.5    Khan, A.R.6
  • 35
    • 70350314114 scopus 로고    scopus 로고
    • Cell-cell interactions in the endocrine pancreas
    • 1:CAS:528:DC%2BD1MXhsVOlsb3P 19817798
    • Jain R, Lammert E. Cell-cell interactions in the endocrine pancreas. Diabetes Obes Metab. 2009;11 Suppl 4:159-67.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 159-167
    • Jain, R.1    Lammert, E.2
  • 36
    • 84921376871 scopus 로고    scopus 로고
    • Beta cell connectivity in pancreatic islets: A type 2 diabetes target?
    • 1:CAS:528:DC%2BC2cXhsl2gtrfI 25323131
    • Rutter GA, Hodson DJ. Beta cell connectivity in pancreatic islets: a type 2 diabetes target? Cell Mol Life Sci. 2015;72:453-67.
    • (2015) Cell Mol Life Sci. , vol.72 , pp. 453-467
    • Rutter, G.A.1    Hodson, D.J.2
  • 37
    • 84867546396 scopus 로고    scopus 로고
    • Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions
    • Nolte-'t Hoen EN, Buermans HP, Waasdorp M, Stoorvogel W, Wauben MH, t Hoen PA. Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions. Nucleic Acids Res. 2012;40:9272-85.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 9272-9285
    • Nolte-'T Hoen, E.N.1    Buermans, H.P.2    Waasdorp, M.3    Stoorvogel, W.4    Wauben, M.H.5    Hoen P A, T.6
  • 38
    • 84892621376 scopus 로고    scopus 로고
    • Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation
    • 1:CAS:528:DC%2BC2cXltFerurc%3D 24196440
    • Forterre A, Jalabert A, Chikh K, Pesenti S, Euthine V, Granjon A, et al. Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation. Cell Cycle. 2014;13:78-89.
    • (2014) Cell Cycle , vol.13 , pp. 78-89
    • Forterre, A.1    Jalabert, A.2    Chikh, K.3    Pesenti, S.4    Euthine, V.5    Granjon, A.6
  • 40
    • 84922527336 scopus 로고    scopus 로고
    • Endogenous RNAs modulate MicroRNA sorting to exosomes and transfer to acceptor cells
    • 1:CAS:528:DC%2BC2cXhsVarsb7L 25159140
    • Squadrito ML, Baer C, Burdet F, Maderna C, Gilfillan GD, Lyle R, et al. Endogenous RNAs modulate MicroRNA sorting to exosomes and transfer to acceptor cells. Cell Rep. 2014;8:1432-46.
    • (2014) Cell Rep , vol.8 , pp. 1432-1446
    • Squadrito, M.L.1    Baer, C.2    Burdet, F.3    Maderna, C.4    Gilfillan, G.D.5    Lyle, R.6
  • 41
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis
    • 1:CAS:528:DC%2BD3MXovFWit7s%3D 11793013
    • Eizirik DL, Mandrup-Poulsen T. A choice of death-the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia. 2001;44:2115-33.
    • (2001) Diabetologia , vol.44 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 42
    • 33750846939 scopus 로고    scopus 로고
    • Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets
    • 1:CAS:528:DC%2BD28XhtVGlsrnL 17003335
    • Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, et al. Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets. Diabetes. 2006;55:2713-22.
    • (2006) Diabetes , vol.55 , pp. 2713-2722
    • Maedler, K.1    Schumann, D.M.2    Sauter, N.3    Ellingsgaard, H.4    Bosco, D.5    Baertschiger, R.6
  • 43
    • 78049293785 scopus 로고    scopus 로고
    • INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells
    • 1:CAS:528:DC%2BC3cXhsV2nsb%2FO 20682686
    • Bonner C, Bacon S, Concannon CG, Rizvi SR, Baquie M, Farrelly AM, et al. INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells. Diabetes. 2010;59:2799-808.
    • (2010) Diabetes , vol.59 , pp. 2799-2808
    • Bonner, C.1    Bacon, S.2    Concannon, C.G.3    Rizvi, S.R.4    Baquie, M.5    Farrelly, A.M.6
  • 44
    • 0037390423 scopus 로고    scopus 로고
    • Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines
    • 1:CAS:528:DC%2BD3sXisVegsLc%3D
    • Lilla V, Webb G, Rickenbach K, Maturana A, Steiner DF, Halban PA, et al. Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines. Endocrinol. 2003;144:1368-79.
    • (2003) Endocrinol , vol.144 , pp. 1368-1379
    • Lilla, V.1    Webb, G.2    Rickenbach, K.3    Maturana, A.4    Steiner, D.F.5    Halban, P.A.6
  • 45
    • 0034006587 scopus 로고    scopus 로고
    • Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion
    • 1:CAS:528:DC%2BD3cXlsFCru7Y%3D 10868964
    • Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes. 2000;49:424-30.
    • (2000) Diabetes , vol.49 , pp. 424-430
    • Hohmeier, H.E.1    Mulder, H.2    Chen, G.3    Henkel-Rieger, R.4    Prentki, M.5    Newgard, C.B.6
  • 46
    • 0023224147 scopus 로고
    • Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection
    • 1:STN:280:DyaL2s3gslWmsQ%3D%3D
    • Gotoh M, Maki T, Satomi S, Porter J, Bonner-Weir S, O'Hara CJ, et al. Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplant. 1987;43:725-30.
    • (1987) Transplant , vol.43 , pp. 725-730
    • Gotoh, M.1    Maki, T.2    Satomi, S.3    Porter, J.4    Bonner-Weir, S.5    O'Hara, C.J.6
  • 47
    • 84857011554 scopus 로고    scopus 로고
    • Isolation and characterization of RNA-containing exosomes
    • 22257828
    • Lasser C, Eldh M, Lotvall J. Isolation and characterization of RNA-containing exosomes. J Vis Exp. 2012;59:e3037.
    • (2012) J Vis Exp , vol.59 , pp. 3037
    • Lasser, C.1    Eldh, M.2    Lotvall, J.3


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